Clinical trials: Diabete Type 1
Diabetes Mellitus, Type 1
The Impact of Two Different Insulin Dose Calculation on Postprandial Glycemia After Mixed Meal.
The aim of the study is to compare the impact of two different insulin dose calculation on postprandial glycemia after mixed meal in children with type 1 diabetes mellitus.
- Trial name
- NCT04124302
- Testing
- Insulin Glulisine, Insulin Aspart, Insulin Lispro
- Where
- Poland
- Volunteers
- 76 people
- Sponsor
- Medical University of Warsaw
Diabetes (DM), Diabete Mellitus
Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups
Mental conditions and disorders (e.g. distress, depressive, anxiety, and eating disorders) are more prevalent in people with diabetes (PWD) and associated with reduced quality of life and impaired glycaemic outcomes.
- Conditions
- Diabetes (DM), Diabete Mellitus, Diabete Type 1, Diabete Type 2
- Trial name
- TwinPeaks (NCT07212075)
- Where
- 3 sites in Germany
- Volunteers
- 1,809 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Diabetes, Diabetes Mellitus, Type 1
Safety and Efficacy of NovoLog vs. Humalog in Insulin Pumps in Children and Adolescents
This trial is conducted in the United States of America (USA). It is demonstrated that intensive insulin therapy resulting in good glycaemic control can reduce or delay the incidence of complications secondary to Type 1 Diabetes.
- Trial name
- NCT00097071
- Testing
- insulin lispro, insulin aspart
- Where
- 52 sites in United States
- Volunteers
- 299 people
- Sponsor
- Novo Nordisk A/S
Diabetes Type 1
Diabetes Intervention Involving Person-centred Nutritional Education
The overall objective for this project is to evaluate the effects of a person-centred education intervention to promote a healthy, sustainable Nordic diet compared with the current practice of providing short dietary information…
- Trial name
- DINE (NCT07258758)
- Testing
- Dietary intervention
- Where
- Sweden
- Volunteers
- 54 people
- Sponsor
- Umeå University
Hypertension, Diabetes Mellitus, Type 1
Improving Blood Pressure Management in Patients With Diabetes
About 22% of Canadians have high blood pressure, or hypertension. However, studies have shown that only 1 out of 5 people with hypertension have their blood pressure controlled.
- Conditions
- Hypertension, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- SCRIP-HTN (NCT00374270)
- Testing
- Lifestyle Counselling; Opinion Leader Influence Statements
- Where
- Canada
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Diabetes, Type I
Efficacy & Safety of Inhaled Insulin in Type 1 Diabetes
To determine the safety and efficacy of inhaled insulin in the treatment of type 1 diabetes
- Trial name
- NCT00308308
- Testing
- Technosphere Insulin, Active comparator
- Where
- 129 sites in United States, Argentina and 8 more
- Volunteers
- 589 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Diabetes, Diabetes Care
Changing Outpatient Diabetes Care With Remote-Patient-Monitoring: A Real World Evidence Study With Pre-Post Comparison
The goal of this observational pre-post study is to evaluate a remote-patient-monitoring-system (RPM-system) integrated within an electronic health record (EHR) system in a real world cohort of approximately 12.000 people with…
- Conditions
- Diabetes, Diabetes Care, Diabetes Type 1, Diabetes Type 2
- Trial name
- NCT07617519
- Testing
- Remote-Patient-Monitoring (RPM)
- Where
- Denmark
- Volunteers
- 12,000 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetes Type 1
Comparison of Insulin's Injection Before or After the Meal in Type 1 Diabetic Patients Treated With Insulin Pump
The current study focuses on terms of use of Insulin Aspart, fast analogue of human insulin and commonly used in the treatment of type 1 diabetes, where it obtained the marketing authorization for this indication.
- Trial name
- BOLUS (NCT02546401)
- Testing
- Insulin Aspart
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Brest
Painful Diabetic Peripheral Neuropathy (PDPN)
Efficacy and Safety of the N0750 Compared to Monotherapies in the Treatment of Painful Diabetic Peripheral Neuropathy
A phase 3, prospective, adaptive, randomized, multicenter, double-blind, triple-masked, parallel clinical trial to evaluate the efficacy and safety of N0750 in relieving pain associated with painful diabetic peripheral neuropathy…
- Trial name
- ENFORCE (NCT06715462)
- Testing
- N0750, Cymbalta®, Lyrica®
- Where
- Brazil
- Sponsor
- Eurofarma Laboratorios S.A.
Diabetes Type 1, Diabetes Type 2 on Insulin
EkiYou-Study-2 : A National Multicentric Trial of the EkiYou Application for Insulin Bolus Calculation
EkiYou-Study-2 is an interventional multicenter randomised controlled clinical investigation according to EU 2017/745. It is conducted in 154 adults with diabetes and treated by multiple daily insulin injections that will be…
- Conditions
- Diabetes Type 1, Diabetes Type 2 on Insulin, Pancreatogenous Diabetes
- Trial name
- NCT06738849
- Testing
- EkiYou V2
- Where
- 16 sites in France
- Volunteers
- 154 people
- Sponsor
- DiappyMed
Diabete Mellitus, Type 1 Diabetes Mellitus
Choices and Experiences Around Closed-loop Therapy in Type 1 Diabetes
Type 1 diabetes requires a lot of work to try to keep glucose levels in the target range. Hybrid closed- loop, also known as artificial pancreas, takes glucose readings from a sensor (continuous glucose monitor) and uses an…
- Trial name
- SELECT HCL (NCT07177404)
- Where
- United Kingdom
- Volunteers
- 166 people
- Sponsor
- University of Nottingham
Diabetes Type 2
"Effect of Dipeptidyl Peptidase IV After Diets in näive Type 2 Diabetic Patients"
The purpose of this study is to demonstrate the secretion of glucose, insulin, glucagon, C-peptide and lipid profile after isocaloric diets with different nutritional compounds (fat, protein and carbohydrate food) in drug näive…
- Trial name
- NCT00881543
- Testing
- Dipeptidyl Peptidase IV inhibitors
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo General Hospital
Diabetes Type 1, Diabetes Mellitus, Type 2
Antenatal Hand Milking for Pregnant Women With Diabetes'
The project is a descriptive cohort study with a retrospective and a prospective group where pregnancy and childbirth data will be studied.
- Conditions
- Diabetes Type 1, Diabetes Mellitus, Type 2, GDM
- Trial name
- NCT04794283
- Testing
- Breast milk
- Where
- Sweden
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Diabetes Mellitus
Diabetes Type 1 and Fitness.
The Diab1Fit Study project aims to a multidirectional assessment of physical activity and its impact in people with type 1 diabetes (DM1).
- Trial name
- Diab1Fit (NCT04968171)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Diabetes Mellitus, Type 1
Clinical Study to Evaluate the Bio-Psychosocial Impact of Mobile App for Diabetes Type 1 ("SOCIAL DIABETES")
Based on international recommendations, the current clinical research project considers the effectiveness of a free diabetes app with a CE (Conformité Européenne) mark, "Social Diabetes", which incorporates the addition of a…
- Trial name
- NCT03455816
- Testing
- Social Diabetes App, Usual clinical monitoring group (Control group)
- Where
- Spain
- Volunteers
- 148 people
- Sponsor
- Soledad Ruiz de Adana
Diabetes Type 1
Home and School Visits Intervention for Children With DM TYPE 1
Home and school visits by multidisciplinary team will improve metabolic control in kids having insulin dependent diabetes mellitus
- Trial name
- NCT02137174
- Testing
- Home and school visits
- Where
- Israel
- Volunteers
- 92 people
- Sponsor
- Ben-Gurion University of the Negev
Diabetes Type 1
Development of Artificial Intelligence Tools for the Detection of Stress Markers and Consideration of Stress States in the Monitoring of Subjects With Type 1 Diabetes
Stress refers to all the reactions of an organism subjected to exogenous or endogenous stress. In the context of diabetes, stress plays a critical role.
- Trial name
- SMART-T1D (NCT06985862)
- Testing
- Voice recording 4 times a day
- Where
- 5 sites in France
- Volunteers
- 35 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Type 1 Diabetes (T1D)
Lactobacillus Johnsonii Supplementation in Adults With T1D
While genetics demonstrated a major risk factor for the development of type 1 diabetes (T1D), microbiota dysbiosis has been suggested as an elicitor in immunological tolerance and of beta cell autoimmunity.
- Trial name
- NCT03961347
- Testing
- L. johnsonii Probiotic
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Diabetes Type 1
Transition of T1DM Patients Aged Over 65 Years Into AHCL (780G) Insulin Pump
Older people with diabetes have a higher risk for cognitive impairment and for physical disability whether this may be effected by an improvement in glucose indices is unknown.
- Trial name
- 780G65+ (NCT06207838)
- Testing
- MiniMed 780G system
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Jagiellonian University
Diabetes Type 1
The MIND Study - Microangiopathy IN Diabetes
This clinical investigation will evaluate two contactless optical devices based on spatial frequency domain and laser speckle technology for quantification of the skin micro-circulation in patients with diabetes mellitus type 1.
- Trial name
- NCT06989190
- Where
- Sweden
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- HJN Sverige AB/Neko Health