Clinical trials: Diabetes During Pregnancy
Diabetes, Gestational
Text-message Reminders to Increase Rates of Postpartum Diabetes Screening in Women With Gestational Diabetes
Purpose: The purpose of this study is to see whether a text-message reminder system will increase the number of women who complete their diabetes screening after delivery.
- Trial name
- NCT02013557
- Testing
- Text-message reminder
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of South Florida
Diabetes Mellitus, Diabetes, Gestational
Recent GDM Lifestyle Intervention
Women with a history of gestational diabetes (GDM) have a substantially increased risk of developing type 2 diabetes. In fact, 50-70% of these women will go on to develop type 2 diabetes within the 20 years following their…
- Trial name
- LIFe (NCT01910805)
- Testing
- Lifestyle and Risk Assessment class
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Diabetes, Gestational
Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes
This clinical trial aims to test whether glibenclamide is non-inferior to insulin for the treatment of gestational diabetes.
- Trial name
- INDAO (NCT01731431)
- Testing
- Insulin, Glyburide
- Where
- France
- Volunteers
- 914 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fetal Macrosomia, Obesity Complicating Childbirth
Investigating the Relationship Between Triglycerides and Fetal Overgrowth in Gestational Diabetes
This is a prospective, observational study which examines the association between maternal triglycerides in the antepartum period and fetal overgrowth in pregnancies complicated by gestational diabetes.
- Conditions
- Fetal Macrosomia, Obesity Complicating Childbirth, Gestational Diabetes
- Trial name
- NCT06067685
- Testing
- Observation
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Polycystic Ovary Syndrome, Pregnancy Complications
A Prospective Cohort Study on the Serum Kisspeptin Levels Throughout Pregnancy in PCOS
The current study aims to investigate the dynamic serum kisspeptin levels throughout pregnancy and to explore its predictive value for GDM in PCOS.
- Trial name
- NCT06545994
- Testing
- Observation
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fudan University
Gestational Diabetes
Intensive Management for Gestational Diabetes
This is a randomized clinical pilot trial designed to assess the feasibility of randomizing obese women with GDM to lower glycemic thresholds compared to standard care.
- Trial name
- GDM-MOMS (NCT02530866)
- Testing
- Lower glycemic targets
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Gestational Diabetes Mellitus, Pregnancy
Trial of Remote Evaluation and Treatment of Gestational Diabetes Mellitus
Diabetes in pregnancy (gestational diabetes) is becoming more common. It can lead to problems for both mothers-to-be and their babies such as causing a large baby and difficult birth.
- Trial name
- TREAT-GDM (NCT01916694)
- Testing
- Blue tooth enabled glucose meter with smart phone application, Self home blood glucose monitoring
- Where
- United Kingdom
- Volunteers
- 203 people
- Sponsor
- University of Oxford
Hyperemesis; Gravidarum, With Dehydration, Gestational Diabetes
Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance Test
Hyperemesis gravidarum (HEG) is not only nausea and vomiting of pregnancy, but it is also a clinical syndrome including endocrine and metabolic complications.
- Trial name
- NCT02963753
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Clinic to Community Connections - Broader Distribution
This study addresses education needs in gestational diabetes care and followup at the staff and patient levels. In the initial phase, nurses and community health workers will complete specific training modules on gestational…
- Trial name
- NCT04474795
- Testing
- Staff -Educational training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Gestational Diabetes, Obesity
Randomizing Two Gestational Diabetes Screening Methods in a Diverse HMO
This project randomizes two different screening strategies for diabetes in pregnancy, among a study population of over 17,500 pregnant women and their babies (over 35,000 total) in a large diverse health maintenance organization…
- Conditions
- Gestational Diabetes, Obesity, Pregnancy
- Trial name
- NCT02266758
- Testing
- GDM Screening Methods
- Volunteers
- 23,792 people
- Sponsor
- Kaiser Permanente
Diabetes Mellitus Gestational Previous Pregnancy
Healthy Eating and Active Living for Diabetes - Gestational Diabetes Mellitus
To examine the effectiveness of a group-based lifestyle modification program followed by peer-led telephone counselling for type 2 diabetes (T2D) and cardiovascular disease risk reduction.
- Trial name
- HEALD-GDM (NCT02483949)
- Testing
- Healthy Eating and Active Living for Diabetes - Gestational Diabetes Mellitus
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Athabasca University
Gestational Diabetes, Inflammation
Effect of Very Low Carbohydrate Diet on Glycemic, Metabolic, Glycated and Inflammatory Markers in Gestational Diabetes Mellitus
Uncontrolled Gestational Diabetes Mellitus may leads to maternal and fetal complications. These complications can be avoided by adopting the dietary modifications along with medications.
- Conditions
- Gestational Diabetes, Inflammation, Metabolic Syndrome, Glucose Intolerance During Pregnancy
- Trial name
- NCT05305352
- Testing
- Very low carbohydrate dietary intervention
- Where
- Pakistan
- Sponsor
- Khyber Medical University Peshawar
Gestational Diabetes
Effect of Conventional vs Intensive Management on Gestational Diabetes and Maternal Fetal Outcomes
This study involved two management protocols to manage diabetes in pregnancy. Sixty patients having GDM will be recruited on the basis of the OGTT and randomly allocated to two management groups.
- Trial name
- NCT07336914
- Testing
- Dietary intervention + Physical Activity + Monitoring, Usual care
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Medical University Peshawar
Pregnancy Related, Gestational Diabetes
The Hoosier Moms Cohort
The Hoosier Moms Cohort (HMC) study's goal is to better understand the pathophysiology underlying the development of gestational diabetes mellitus (GDM) in pregnant women and its transition to Type 2 diabetes mellitus in mothers…
- Trial name
- NCT03696368
- Where
- 6 sites in United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Indiana University
Maturity-Onset Diabetes of the Young
Impact on Birth Weight of Two Therapeutic Strategies (Insulin Therapy From the Beginning of Pregnancy vs. Insulin Therapy Initiated According to Fetal Growth Evaluated by Ultrasonography Measurements) in Pregnant Women With Monogenic Diabetes
Maturity-onset diabetes of youth (MODY) are the most frequent monogenic diabetes with autosomic dominant inheritance (2% of diabetes).
- Trial name
- MODY2 (NCT02556840)
- Testing
- insulin therapy
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gestational Diabetes Mellitus in Pregnancy
D-chiro Inositol in Prevention of Gestational Diabetes Mellitus in China
Inositol is a type of food additives, which plays an important role in insulin signal pathway and is related to insulin sensitivity.
- Trial name
- NCT04801485
- Testing
- D-chiro inositol
- Where
- China
- Volunteers
- 291 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Gestational Diabetes
Continuous Glucose Monitoring for Screening for Diabetes in Pregnancy
The purpose of this study is to evaluate whether Continuous glucose monitoring (CGM) for diagnosis of gestational diabetes mellitus (GDM) improves maternal and neonatal outcomes related to GDM and to evaluate whether CGM for GDM…
- Trial name
- NCT05430204
- Testing
- Group 1: one-hour GCT, Group 2: CGM placement
- Where
- United States
- Volunteers
- 1,628 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gestational Diabetes Mellitus
Correlation Between Environmental Pollution and Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) refers to the abnormal glucose metabolism index of pregnant women during pregnancy. At present, about 15% of pregnant women will develop GDM in the second and third trimester, which seriously…
- Trial name
- NCT05388721
- Testing
- Clinical data and specimen collection
- Where
- China
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Gestational Diabetes Mellitus in Pregnancy
First Trimester Prediction of Gestational Diabetes Mellitus by Continuous Glucose Monitoring.
Gestational diabetes mellitus (GDM) is the most common complication of pregnancy, with an incidence rate of 10-15% [1]. Common risk factors for GDM are increased maternal age and weight and as a consequence of women delaying…
- Trial name
- GLUCO-GCM (NCT06874907)
- Testing
- Glucose monitoring
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Gestational Diabetes
Early Prediction of Gestational Diabetes in High-risk Women Based on Breath Metabolomics
This study aim to develope novel breath markers of gestational diabetes through a prospective high-risk population cohort study and achieve early prediction of gestational diabetes based on an interpretable machine learning model.
- Trial name
- NCT06753734
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Tianjin Central Hospital of Gynecology Obstetrics