Clinical trials: Diabetes During Pregnancy
Gestational Diabetes, Diabetes, Gestational
Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus
Gestational diabetes (GDM) is a significant clinical and public health burden, affecting over 400,000 pregnant women in the United States each year.
- Conditions
- Gestational Diabetes, Diabetes, Gestational, Pregnancy in Diabetes
- Trial name
- MATCh-GDM (NCT03029702)
- Testing
- Insulin, Glyburide, Metformin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Maisa N. Feghali, MD
Gestational Diabetes Mellitus, Pregnancy Complications
Gestational Diabetes Mellitus (GDM) in Pregnant Women
The purpose of the trial is to discover and predict the development of GDM of pregnant women in their first trimester.
- Trial name
- NCT05265741
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Long Island University
Gestational Diabetes, Metformin
Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women
Gestational diabetes (GD) is defined by a hyperglycemia discovered during pregnancy, leading to fetal and maternal complications which may be prevented by reaching very strict glycaemia targets.
- Conditions
- Gestational Diabetes, Metformin, Treatment, Oxidative Stress
- Trial name
- NCT01756105
- Testing
- Metformin, Rapid acting analog insulin Intermediate acting NPH Insulin
- Where
- 5 sites in France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Strasbourg, France
Gestational Diabetes
The Acute Effect of Physical Activity on Postprandial Blood Glucose in Pregnant Women
The aim of the project is to investigate the acute effect of exercise on blood glucose after food consumption. Thereby the investigators wish to achieve knowledge that can improve prevention and treatment of gestational…
- Trial name
- NCT03641170
- Testing
- Physical activity, Inactivity, Fixed diet.
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pregnant Women, Gestational Diabetes
Education of Pregnant Women at Risk of Gestational Diabetes
There are studies in the literature showing that there is a decrease in the number of pregnant women diagnosed with gestational diabetes and improvements in parameters related to maternal and infant health, with the education to…
- Trial name
- NCT05568277
- Testing
- Education on preventive health behaviors based on Pender's Health Promotion Model
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Type 1 Diabetes, Pregnancy in Diabetic
Telemedicine in Pregnant Women With Type 1 Diabetes Mellitus
Hypothesize that co-managing pregnant type 1 diabetics with telemedicine will have at least equivalent outcomes to those managed with standard care.
- Trial name
- NCT04278664
- Volunteers
- 5 people
- Sponsor
- Ana Braescu
Pre-Eclampsia, Obesity
Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women
The purpose of this study is to conduct a pilot randomized controlled trial of a food is medicine community health worker intervention called the Women's Health Delaware Food Farmacy compared to the usual standard of care among…
- Conditions
- Pre-Eclampsia, Obesity, Gestational Diabetes, Gestational Hypertension
- Trial name
- NCT06180811
- Testing
- Women's Health Delaware Food Farmacy, Usual Standard of Care
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Christiana Care Health Services
Portal Blood Pressure, Liver Surgery
Optimization of Hepatic Hemodynamics During Liver Surgery
The purpose of this study is to determine if vasopressin and nitroglycerin in combination will affect hepatic hemodynamics, in the setting of liver surgery.
- Conditions
- Portal Blood Pressure, Liver Surgery, Hepatic Hemodynamics
- Trial name
- NCT02993640
- Testing
- vasopressin + nitro
- Volunteers
- 13 people
- Sponsor
- Sahlgrenska University Hospital
Diabetic Nephropathies
This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Tolerated
The primary objective of this current trial is to investigate the safety and tolerability of 3 oral doses of BI 690517 over 28 days in female and male patients with diabetic nephropathy as add-on-therapy to Angiotensin Converting…
- Trial name
- NCT03165240
- Testing
- BI 690517, Eplerenone
- Where
- 40 sites in Denmark, France and 8 more
- Volunteers
- 62 people
- Sponsor
- Boehringer Ingelheim
Gestational Diabetes
Glucose Testing in GDM: Adherence to One- Versus Two-hour Postprandial Glucose Monitoring in Gestational Diabetics
The purpose of this study is to evaluate if in patients with gestational diabetes (GDM), adherence to postprandial glucose monitoring differs when performed 1-hour versus 2-hours after eating.
- Trial name
- NCT05062460
- Testing
- 1 hour Blood glucose monitoring, 2 hour blood glucose monitoring
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Weill Medical College of Cornell University
Gestational Diabetes Mellitus in Childbirth, Neurodevelopmental Disorders
Early Biomarkers of Neurodevelopment in Offspring of Diabetic Mothers
The prospective multicenter study GD-Brain provides a better knowledge on the basis of neurological impairment in children born to mothers with gestational diabetes (GDM).
- Trial name
- GD-BRAIN (NCT03032991)
- Where
- Spain
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Gestational Diabetes, Glucose Tolerance Impaired in Pregnancy
Food Product for Management of Gestational Diabetes
The goal of this pilot open pre-post clinical trial is to test effects of a wholegrain product in patients with newly diagnosed gestational diabetes.
- Conditions
- Gestational Diabetes, Glucose Tolerance Impaired in Pregnancy, Glucose Tolerance Impaired, Pregnancy Related
- Trial name
- NCT05917808
- Testing
- Ready-to-eat wholegrain porridge
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Stoffwechselzentrum Rhein - Pfalz
Diabetes
A Behavioral Intervention to Prevent Impaired Glucose Tolerance Diabetes Mellitus (DIGITAL-I)
The national epidemiological survey showed that the prevalence rate of pre-diabetes was up to 35.7% in China. Previous study indicated that lifestyle intervention in people with impaired glucose tolerance could delay the onset of…
- Trial name
- NCT03987438
- Testing
- Lifestyle intervention with APP
- Where
- China
- Volunteers
- 1,336 people
- Sponsor
- Peking University Third Hospital
Gestational Diabetes
Patterns and Glycaemic Endpoints for Diagnosing Gestational Diabetes
Gestational diabetes (GDM) develops during pregnancy and is becoming increasingly common. The condition is associated with adverse outcomes for mother and baby during both the pregnancy and delivery period.
- Trial name
- PAGED-GDM (NCT05981547)
- Testing
- Libre 3 continuous glucose monitoring sensor
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Gestational Diabetes, Telemonitoring
Telemonitoring of Pregnancies Complicated With Gestational Diabetes Mellitus.
This interventional study examines the addition of telemonitoring (TM) in prenatal care for gestational diabetes mellitus (GDM).
- Trial name
- TEGEDIM (NCT06251466)
- Testing
- iHealth Gluco-Smart application
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Hasselt University
Gestational Diabetes
A Pragmatic Approach to Lowering the Risk of Diabetes Mellitus After A Diagnosis of Gestational Diabetes Mellitus
A Pilot of Metformin Postpartum
- Trial name
- NCT04615351
- Testing
- Metformin
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Pregnancy Complications
Health Belief Model Based Education for Pregnant Women With Gestational Diabetes
Gestational diabetes (GDM) is a type of diabetes that occurs as a result of intolerance of carbohydrate metabolism during pregnancy in an individual whose blood glucose concentration is within normal limits before pregnancy.
- Trial name
- NCT06740695
- Testing
- Education group
- Volunteers
- 80 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Gestational Diabetes, Diabetes, Gestational
Gestational Diabetes: a Cohort Study
Gestational diabetes (GDM) is the most common hormonal complication during pregnancy. Its occurrence implies an increased risk of maternal and fetal complications and, therefore, its diagnosis and treatment are extremely…
- Conditions
- Gestational Diabetes, Diabetes, Gestational, Diabetes Mellitus in Pregnancy, Diabetes Mellitus, Type 2
- Trial name
- NCT03307486
- Where
- Brazil
- Volunteers
- 1,400 people
- Sponsor
- University of Sao Paulo General Hospital
Gestational Diabetes, Pregestational Diabetes
Permissive Intrapartum Glucose Control
The purpose of this study is to assess whether permissive intrapartum glycemic control compared to usual care would lead to similar rate of neonatal hypoglycemia among people with diabetes.
- Trial name
- NCT05553275
- Testing
- Usual Care, Permissive intrapartum glucose control
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gestational Diabetes Mellitus
The Early Diagnosis of Gestational Diabetes Mellitus Study
The main purpose of the study is to evaluate an OGTT at 18 to 20 gestational weeks as an early diagnosis method of GDM in low risk pregnant women.
- Trial name
- EDoGDM (NCT02740283)
- Testing
- glycemic monitoring, dietary guide
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University