Clinical trials: Diabetes During Pregnancy
Health Problems in Pregnancy, Pregnancy Outcomes
Peking University Birth Cohort in Tongzhou
The PKUBC-T is a prospective cohort study carried out in Tongzhou district of Beijing, China. The primary aim of this study is to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal…
- Conditions
- Health Problems in Pregnancy, Pregnancy Outcomes, Gestational Diabetes, Gestational Hypertension
- Trial name
- PKUBC-T (NCT03814395)
- Testing
- No intervention
- Where
- China
- Volunteers
- 5,426 people, healthy volunteers welcome
- Sponsor
- Peking University
Gestational Diabetes Mellitus in Pregnancy
Can Albumin/C-reactive Protein Ratio be Utilized for Predicting Gestational Diabetes Diagnosis or the Adverse Outcomes
This study provides a comprehensive evaluation of the potential utility of the albumin/high-sensitivity C-reactive protein (hsCRP) ratio in diagnosing gestational diabetes mellitus (GDM) and predicting adverse pregnancy outcomes.
- Trial name
- Alb/hsCRP (NCT06761053)
- Testing
- Intervention/Exposure for the GDM Group (Experimental Arm), Intervention/Exposure for the Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemalpasa Government Hospital
Gestational Diabetes, Sleep Apnea
Sleep Apnea and Gestational Diabetes
The investigators hypothesize that pregnant women with gestational diabetes will have a high incidence of sleep apnea, and that the treatment of sleep apnea will lead to improved glucose control in these women.
- Trial name
- NCT02108197
- Testing
- Continuous positive airway pressure (S9, ResMed)
- Where
- Thailand
- Volunteers
- 82 people
- Sponsor
- Ramathibodi Hospital
Anxiety, Life Style
The Laughter, Pregnancy, Anxiety and Llife Quality
Gestational Diabetes is one of the most common medical complications during pregnancy. It is seen between the 24th and 28th weeks of pregnancy with the increase in insulin resistance in the second trimester and ends with the end…
- Conditions
- Anxiety, Life Style, Gestational Diabetes, Pregnancy Related
- Trial name
- NCT06556927
- Testing
- Laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Diabetes, Gestational
Insulin Sensitivity and Secretion During Pregnancy and Post Partum in Women With Gestational Diabetes.
Aim of the study: To define insulin requirement during pregnancy and to identify the rapid changes in insulin sensitivity around parturition and the first 6 months post partum.
- Trial name
- NCT02770079
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
GDM, Blood Glucose
the Effect of Mobile Medical Used for the Standardized Management of Gestational Diabetes
A multicenter, randomized controlled trial was conducted to investigate whether health education and life style management through WeChat group chat was more effective in controlling blood glucose (BG) than standard clinic…
- Conditions
- GDM, Blood Glucose, Compliance, Patient, Diet Habit
- Trial name
- NCT04424238
- Testing
- m-health management
- Volunteers
- 400 people
- Sponsor
- Peking Union Medical College Hospital
Gestational Diabetes Mellitus, Pregnancy, High Risk
Continuous Glucose Monitoring (CGM) Substudy of the DECIDE RCT
This is a nested multicenter prospective cohort conducted concurrently and in conjunction with the DECIDE two-arm, pragmatic non-inferiority comparative effectiveness Randomized Controlled Trial (RCT) (NCT06445946) of metformin…
- Trial name
- DECIDE CGM (NCT06490874)
- Testing
- CGM device - Metformin group, CGM device - Insulin group
- Where
- 4 sites in United States
- Sponsor
- Ohio State University
GDM
Efficacy of Lactobacillus Rhamnosus LRa05 in Gestational Diabetes
This study aims to comprehensively evaluate the multifaceted impacts of Lactobacillus rhamnosus LRa05 on patients with gestational diabetes.
- Trial name
- NCT06901791
- Testing
- Conventional treatment and Probiotic
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Gestational Diabetes
Gestational Diabetes - PrEvention of PostPartum Diabetes Study
Gestational diabetes is the most common metabolic abnormality during pregnancy. In a Swedish population 2-10% of all pregnant women are diagnosed with gestational diabetes mellitus (GDM).
- Trial name
- PEPP (NCT05112588)
- Testing
- Intervention
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Diabetes Mellitus in Pregnancy, Diabetes, Gestational
Diabetes in Pregnancy and Pregnancy Outcomes
To compare the clinical, glycemic profile and therapy as well as pregnancy complications and infant mortality among diabetic mothers in Indonesia.
- Trial name
- NCT03602846
- Testing
- Medical Nutrition Therapy, Insulin, Oral Antidiabetics
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Diabetes, Gestational
Effect of Carbohydrate Distribution on Blood Glucose in Women With Gestational Diabetes Mellitus (GDM)
This study aims to investigate whether high-morning carbohydrate intake (HMK) compared with low-morning carbohydrate intake (LMK) affects glycemic variability in GDM patients based on Continuous glucose monitoring (CGM).
- Trial name
- NCT03835208
- Testing
- High/low carbohydrate distribution
- Where
- 2 sites in Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Birth Defects, Type 2 Diabetes
Exenatide Pregnancy Registry - Type 2 Diabetes in Pregnancy
This is an observational, prospective cohort study describing pregnancy outcomes in women with pre-existing (prior to pregnancy) type 2 diabetes who have been exposed to any formulation of exenatide during pregnancy.
- Conditions
- Birth Defects, Type 2 Diabetes, Preterm Birth
- Trial name
- Exenatide (NCT00579150)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- AstraZeneca
Diabetes
Community Approach to Reduce the Risks of Diabetes After Gestational Diabetes Mellitus
Objective: The current study examined the effectiveness of a culturally-appropriate adaptation of the diabetes prevention program (DPP) curriculum in reducing type 2 diabetes risk in Latinas with a history of gestational diabetes…
- Trial name
- NCT01613937
- Testing
- Dulce Mother lifestyle training program
- Volunteers
- 67 people
- Sponsor
- Scripps Whittier Diabetes Institute
Gestational Diabetes, Diabetes
The DNA Methylation of ARHGEF11 in Macrosomia
Background Macrosomia at birth is associated with subsequent susceptibility to obesity, abnormal glucose metabolism, hypertension and dyslipidaemia.
- Conditions
- Gestational Diabetes, Diabetes, Macrosomia, Fetal
- Trial name
- NCT03165643
- Testing
- OGTT
- Volunteers
- 239 people
- Sponsor
- Peking University First Hospital
Pregnancy, Complications, Gestational Diabetes
Glucose Empowerment Through Monitoring and Social Support in Pregnancy
The purpose of the research is to learn whether wearing a continuous glucose monitor that shows blood glucose levels in real time on a smart phone app and participating in a group chat with other research participants will help…
- Trial name
- GEMS-P (NCT07009704)
- Testing
- Mobile-based social support, Real-time continuous glucose monitoring
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Tufts Medical Center
Pregnant Patients at Risk of Gestational Diabetes
A Randomized Controlled Trial of Prepared vs. Unprepared Food
The goal of this study is to assess the feasibility of different food interventions, delivered through insurance providers, for addressing food insecurity in patients at risk of gestational diabetes (diabetes in pregnancy).
- Trial name
- NCT07800182
- Testing
- Prepared meals, Unprepared Pantry/Produce box
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Diabetes, Gestational, Perinatal Disorder
MeDiGes Study: Metformine Use in Gestational Diabetes
Women with gestational diabete (GD) who do not meet glycemic control objectives with diet will be assigned to two treatment groups randomly.
- Conditions
- Diabetes, Gestational, Perinatal Disorder, Puerperal Disorder
- Trial name
- FIMMET201501 (NCT04222348)
- Testing
- Metformin, Insulin Detemir
- Volunteers
- 200 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
A diagnosis of gestational diabetes mellitus (GDM)has significant implications for the future health of the mother. GDM is often the culmination of years of unrecognized and unmodified diabetes risk factors that lead to overt and…
- Conditions
- Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus, Metabolic Syndrome, Impaired Glucose Tolerance
- Trial name
- NCT01234649
- Testing
- Metformin XR plus liraglutide
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Woman's
GDM
Effect of a Continuous Glucose Monitoring on Maternal and Neonatal Outcomes in Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance first diagnosed during pregnancy [1]. It is associated with adverse pregnancy outcome for the mother, and the fetus with consequences regarding future…
- Trial name
- NCT02838147
- Testing
- FreeStyle sensors., Glucometer
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Gestational Diabetes, Prediabetes; Complicating Pregnancy
Predicting Dysglycemia in Individuals With Gestational Diabetes Immediately Postpartum Using Continuous Glucose Monitoring
Gestational diabetes is one of the most common medical disorders in pregnancy and is a major risk factor for the postpartum development of dysglycemia.
- Conditions
- Gestational Diabetes, Prediabetes; Complicating Pregnancy, Type 2 Diabetes, Pregnancy Related
- Trial name
- PREDISPOSE (NCT04972955)
- Testing
- Freestyle Libre 2
- Where
- 4 sites in Canada
- Volunteers
- 240 people
- Sponsor
- University of Manitoba