Clinical trials: Diabetes During Pregnancy
Gestational Diabetes
Effects of Probiotics on Gut Microbiota Composition and Metabolic Outcomes in Post- Gestational Diabetes Women
Risk of developing diabetes at a younger age among women with a previous history of gestational diabetes mellitus (post-GDM) has increased by 10-fold compared to the healthy women.
- Trial name
- NCT05273073
- Testing
- Probiotics
- Where
- Malaysia
- Volunteers
- 166 people
- Sponsor
- National University of Malaysia
Pregnancy, Gestational Diabetes Mellitus (GDM)
Study of Betatrophin Levels in Patients With Type 2 Diabetes and Gestational Diabetes and Healthy Subjects
Betatrophin is a newly identified hormone that promotes pancreatic beta cell proliferation, improves glucose tolerance and regulates lipids metabolism.
- Conditions
- Pregnancy, Gestational Diabetes Mellitus (GDM), Type 2 Diabetes
- Trial name
- NCT02025673
- Volunteers
- 200 people
- Sponsor
- Qingdao University
Gestational Diabetes Mellitus in Pregnancy, Anxiety
Effects of Rhythm-Based Music on Pregnancies With Gestational Diabetes
This study is for people who have gestational diabetes, a type of diabetes that happens during pregnancy. People with gestational diabetes may feel more anxious than others during pregnancy.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Anxiety, Blood Sugar; High
- Trial name
- NCT06970886
- Testing
- Rhythm-Based Music Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Esin Ceber Turfan, Professor
Gestational Diabetes, Hypertensive Disorder of Pregnancy
Mobile-based Obstetric Monitoring for Pregnancies Complicated by Hypertension and/or Diabetes (MOM-HD)
Hypertensive disorders during pregnancy (HDP) and gestational diabetes (GDM) are among the leading complications in pregnancy, significantly contributing to global maternal and fetal morbidity and mortality.
- Trial name
- MOM-HD (NCT07243886)
- Testing
- MOM-HD, Standard Care
- Where
- 3 sites in Nepal
- Volunteers
- 864 people
- Sponsor
- Rutgers, The State University of New Jersey
Pregnancy Complications, Gestational Diabetes
Early Versus Late Monitoring Among Pregnant Women With a History of Gestational Diabetes
The goal of this study investigate if pregnant women with a history of gestational diabetes (GDM) have better pregnancy outcomes if they test their blood glucose four times a day early in the pregnancy versus having an oral…
- Trial name
- NCT06545227
- Testing
- continuous blood glucose monitoring in a subset of women (n=25) in the early monitoring group., Collection of urine, maternal blood at baseline and 28 weeks in a subset of women (n=25), Collection of umbilical cord blood, placental samples and cord tissue in a subset of women (n=25)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
Gestational Diabetes Mellitus, Pregnancy Complications
Gestational Diabetes Mellitus (GDM) in Pregnant Women
The purpose of the trial is to discover and predict the development of GDM of pregnant women in their first trimester.
- Trial name
- NCT05265741
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Long Island University
Diabetes Mellitus, Type 2, Diabetic Kidney Disease
Renohemodynamic Effects of Combined empagliflOzin and LosARtan
Worldwide, diabetic kidney disease (DKD) is the most common cause of chronic and end stage kidney disease. In parallel with the ever-increasing rates of obesity and type 2 diabetes (T2D), the incidence of DKD is expected to…
- Trial name
- RECOLAR (NCT04238702)
- Testing
- Empagliflozin 10 MG, Losartan 50Mg Tab
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Amsterdam UMC, location VUmc
Gestational Diabetes, Weight Loss
Smartphone App to Restore Optimal Weight in Women With Recent Gestational Diabetes
Gestational diabetes (GDM) complicates about 20% of pregnancies in Singapore. These women are at high risk of developing type 2 diabetes years after pregnancy; seven times more likely than normal.
- Conditions
- Gestational Diabetes, Weight Loss, Diet Habit
- Trial name
- SPAROW (NCT03324737)
- Testing
- Interactive Smartphone App
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University Hospital, Singapore
Diabetes Mellitus, Type 2, Congestive Heart Failure
Improving Patient Prioritization During Hospital-homecare Transition
This research work is focused on building and evaluating one of the first evidence-based clinical decision support tools for homecare in the United States.
- Conditions
- Diabetes Mellitus, Type 2, Congestive Heart Failure, Obstructive Pulmonary Disease, Dyspnea
- Trial name
- PREVENT (NCT04136951)
- Testing
- PREVENT clinical decision support
- Where
- 2 sites in United States
- Volunteers
- 1,915 people
- Sponsor
- Columbia University
Gestational Diabetes
Mobile Health App to Reduce Diabetes in Latina Women
The proposed project sought to develop a culturally- and individually-tailored, plain-language Spanish/English mobile phone intervention for Latinas with prior gestational diabetes (GDM).
- Trial name
- NCT04149054
- Testing
- Mobile health app called "Hola Bebe"
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Environment and Health Group, Inc.
Gestational Diabetes
Education Nutritional Video for Gestational Diabetics
The purpose of this research study is to find out if watching an educational video about nutrition helps participants learn about how different foods affect their blood sugar and how Gestational Diabetes affects pregnancy.
- Trial name
- NCT03859193
- Testing
- Nutritional Video
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Virginia Commonwealth University
Gestational Diabetes, Oxidative Stress
Role of NADPH Oxidase in Microvascular Dysfunction Following GDM
The purpose of this investigation is to examine NADPH oxidase as a source of reactive oxygen species contributing to aberrant microvascular function in otherwise healthy women with a history of GDM.
- Conditions
- Gestational Diabetes, Oxidative Stress, Vascular Endothelial Function
- Trial name
- NCT05946798
- Testing
- Acetylcholine, Insulin aspart
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Clinic to Community Connections - Broader Distribution
This study addresses education needs in gestational diabetes care and followup at the staff and patient levels. In the initial phase, nurses and community health workers will complete specific training modules on gestational…
- Trial name
- NCT04474795
- Testing
- Staff -Educational training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Gestational Diabetes
Therapeutic Synergy of Probiotic Augmented Conventional Antidiabetic Pharmacotherapy in Gestational Diabetes Mellitus
1. To compare the effects of metformin, insulin, and their combination with multistrain probiotics on glycemic control and insulin resistance in women with gestational diabetes mellitus (GDM), assessed by FPG, HbA1c, fasting…
- Trial name
- NCT07645001
- Testing
- GRP 1 Tab metformin, GRP 2 Inj insulin, GRP 3 Tab metformin + HI flora sachet
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Riphah International University
Gestational Diabetes Mellitus
Humalog® Mix50/50(tm) as a Treatment for Gestational Diabetes
Evaluation of the Safety and Efficacy of Humalog® Mix50/50TM administered as 3 injections daily to Humalog® plus Humulin N® insulin administered as 6 separate injections daily in terms of glucose control for women with…
- Trial name
- NCT01613807
- Testing
- Insulin LISPRO, Insulin, Long-Acting and Insulin
- Volunteers
- 40 people
- Sponsor
- Sansum Diabetes Research Institute
Gestational Diabetes Mellitus
The Impact of Vitamin D Supplementation on Pregnant Women With the Risk of GDM
A clinical trial will be conducted in Chemical pathology department in collaboration with Gyne \&Obs department of PRH, IIMC over a period of 02 years w.e.f. December 15, 2023.
- Trial name
- NCT06139133
- Testing
- Vitamin D supplementation
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- IIMC, Riphah International University, Pakistan
Gestational Diabetes
Pre-meal Consumption of Whey in Gestational Diabetes Mellitus From Diagnosis to Delivery
The main objective of the study is to investigate the metabolic effects of whey protein (whey protein isolate, WPI, (Lacprodan® ISO.Water.
- Trial name
- NCT04856800
- Testing
- Whey
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- University of Aarhus
Gestational Diabetes
Early Prediction of Gestational Diabetes in High-risk Women Based on Breath Metabolomics
This study aim to develope novel breath markers of gestational diabetes through a prospective high-risk population cohort study and achieve early prediction of gestational diabetes based on an interpretable machine learning model.
- Trial name
- NCT06753734
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Tianjin Central Hospital of Gynecology Obstetrics
Pregnancy Diabetic
Pregnancy Remote Monitoring of Women at Risk for Gestational Diabetes
Background: Remote monitoring (RM) is a new screenings- and or diagnostic tool in healthcare. In 2015, the PREMOM study (Pregnancy Remote Monitoring), in which patients with gestational hypertensive diseases did received a RM…
- Trial name
- NCT03491436
- Testing
- iHealth Align
- Where
- Belgium
- Sponsor
- Hasselt University
Pregnancy, Gestational Diabetes Mellitus (GDM)
Polyphenol Intake, Mediterranean Diet Adherence, and Oxidative Stress in Pregnancy
This study is a randomized controlled clinical trial designed to evaluate the effect of a polyphenol-rich dietary intervention during pregnancy on endothelial function, oxidative stress biomarkers, and maternal and neonatal…
- Conditions
- Pregnancy, Gestational Diabetes Mellitus (GDM), Preeclampsia, Hypertension, Pregnancy-Induced
- Trial name
- PREGPOLY (NCT07656532)
- Testing
- Natural Non-Alkalized Cocoa, Polyphenol-Rich Dietary Counseling
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salamanca