Clinical trials: Diabetes During Pregnancy
Obesity, Gestational Diabetes
Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics
The primary objective of the STRIVE study is to compare two implementation strategies for Diabetes Prevention Program delivery: an in-person health coach strategy (standard 24 in-person sessions at WIC clinics) vs.
- Conditions
- Obesity, Gestational Diabetes, Lifestyle, Healthy, Glucose Intolerance During Pregnancy
- Trial name
- STRIVE (NCT06116149)
- Testing
- In-person health coach delivery of the GLB, Technology-assisted health coach delivery of the GLB
- Where
- United States
- Volunteers
- 722 people, healthy volunteers welcome
- Sponsor
- Tulane University
Maternal Cardiometabolic Health, Molecular Impact of Psychological Stress and Socioeconomic Adversity
Conscious Pregnancy: Supporting Maternal Cardiometabolic Health With Mindfulness
A pilot randomized control trial (RCT) to examine the efficacy of a culturally tailored mindfulness intervention upon fasting cardiometabolic factors (including markers of glycemic control) and inflammatory gene expression in…
- Conditions
- Maternal Cardiometabolic Health, Molecular Impact of Psychological Stress and Socioeconomic Adversity, Maternal Inflammatory Markers, Maternal Diabetes
- Trial name
- NCT06898658
- Testing
- Mindfulness Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Fetal Macrosomia, Obesity Complicating Childbirth
Investigating the Relationship Between Triglycerides and Fetal Overgrowth in Gestational Diabetes
This is a prospective, observational study which examines the association between maternal triglycerides in the antepartum period and fetal overgrowth in pregnancies complicated by gestational diabetes.
- Conditions
- Fetal Macrosomia, Obesity Complicating Childbirth, Gestational Diabetes
- Trial name
- NCT06067685
- Testing
- Observation
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Gestational Diabetes, Pregnancy
Integrating the Use of Calibration-Free Continuous Monitoring for Pregnancy Glucose Profiling: I-Profile Study
This study aims to test the following hypotheses in a longitudinal, observational study in pregnant women who will be randomized to received either a Blinded or Unblinded CGM sensor and followed-up 6-12 weeks after delivery: 1.
- Trial name
- I-Profile (NCT05123248)
- Testing
- Blinded Group, Unblinded group
- Where
- Singapore
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Gestational Diabetes
Late Metabolic Effects of Metformin Therapy in Gestational Diabetes
Metformin in widely used as the treatment of gestational diabetes. However, it is not known whether exposure to metformin in utero has late metabolic effects on the child.
- Trial name
- DIARA2 (NCT02417090)
- Testing
- Insulin, Metformin
- Volunteers
- 173 people
- Sponsor
- Turku University Hospital
Anemia of Pregnancy, Gestational Diabetes
SMART Health Pregnancy 2 - Intervention to Reduce Anaemia and Cardiometabolic Risk During Pregnancy and in the First Year Following Birth
The goal of this clinical trial is to determine if a complex intervention called SMARThealth Pregnancy can improve the detection and management of high-risk conditions during pregnancy and in the first year after birth in women…
- Conditions
- Anemia of Pregnancy, Gestational Diabetes, Gestational Hypertension, Pre-Eclampsia
- Trial name
- NCT05752955
- Testing
- SMARThealth Pregnancy
- Where
- India
- Volunteers
- 3,446 people
- Sponsor
- The George Institute
Diabetes Mellitus, Type 2, Chronic Kidney Diseases
REGROUP: Renohemodynamic Effects empaGliflozin in vaRiOUs Populations
Worldwide, diabetic kidney disease (DKD) is the most common cause of chronic and end stage kidney disease. Large-sized prospective randomized clinical trials indicate that intensified glucose and blood pressure control, the…
- Trial name
- REGROUP (NCT04243850)
- Testing
- Empagliflozin 10 MG, Caffeine
- Sponsor
- Amsterdam UMC, location VUmc
Gestational Diabetes
Glucose Testing in GDM: Adherence to One- Versus Two-hour Postprandial Glucose Monitoring in Gestational Diabetics
The purpose of this study is to evaluate if in patients with gestational diabetes (GDM), adherence to postprandial glucose monitoring differs when performed 1-hour versus 2-hours after eating.
- Trial name
- NCT05062460
- Testing
- 1 hour Blood glucose monitoring, 2 hour blood glucose monitoring
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Weill Medical College of Cornell University
Gestational Diabetes
Impact of Blood Glucose at the First Trimester of Pregnant Women With Gestational Diabetes on Maternal and Fetal Outcomes and Metabolic Disorders: a Multi-central Prospective Cohort Study
The study is to investigate the impact of blood glucose management at the first trimester of pregnant women with gestational diabetes on the maternal and fetal outcomes and metabolic disorder.
- Trial name
- NCT01833559
- Testing
- Dietary control, Insulin
- Where
- China
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Gestational Diabetes, PreDiabetes
mHealth Smartphone App and Postpartum Glucose Intolerance for Patients With GDM
Without intervention, approximately 70% of women diagnosed with GDM will develop type 2 diabetes mellitus in their lifetime. Abnormal results of a 2 hour oral glucose tolerance test (OGTT) performed as early as 2 days postpartum…
- Conditions
- Gestational Diabetes, PreDiabetes, Pregnancy Related, Pregnancy, High Risk
- Trial name
- NCT05597943
- Testing
- Malama App
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tufts Medical Center
Gestational Diabetes Mellitus (GDM), Glucose Intolerance During Pregnancy
Early Screening for Gestational Diabetes Mellitus in a Low Risk Population
This new feasibility pilot study aims to refine the design and protocols for a larger trial that will investigate the potential benefits of early oral glucose tolerance test (OGTT) screening in a population traditionally defined…
- Trial name
- EaGeR (NCT06704035)
- Testing
- Early OGTT Results Revealed
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Weight Reduction
Avoiding Diabetes After Pregnancy Trial
The Avoiding Diabetes After Pregnancy Trial (ADAPT) study was designed to test the effectiveness of interventions that potentially increase the adoption of Diabetes Prevention Program (DPP) elements by women who had a pregnancy…
- Trial name
- ADAPT (NCT01923350)
- Testing
- Weight Reduction Intervention, Weight Reduction Control Arm, Tested for diabetes
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Social & Scientific Systems Inc.
Intrahepatic Cholestasis of Pregnancy, Gestational Diabetes Mellitus
The Metabolic Profile in Intrahepatic Cholestasis of Pregnancy and Diabetes Mellitus
ICP is known to cause abnormal bile acid homeostasis and to be associated with an increased risk of diseases of the biliary system in later life. There have been small studies (Dann et al. 2006; Wójcicka-Jagodzińska et al.
- Trial name
- NCT01499524
- Where
- 2 sites in United Kingdom
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Gestational Diabetes
Remote Monitoring of Diabetes in Pregnancy: a Feasibility Study
When women with diabetes become pregnant it is particularly important to control blood sugar levels to prevent complications. Women are advised to test their blood glucose levels seven times a day and to attend antenatal and…
- Trial name
- Tele-Mum (NCT01630759)
- Testing
- Telemonitoring, Control
- Where
- 2 sites in Ireland, United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Ulster
Diabetes, Gestational, PreDiabetes
A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes
This study is testing whether daily metformin for 1 year postpartum can reduce risk of diabetes in patients who had gestational diabetes.
- Conditions
- Diabetes, Gestational, PreDiabetes, Diabetes Mellitus, Type 2
- Trial name
- NCT05280496
- Testing
- Metformin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Tufts Medical Center
Gestational Diabetes Mellitus
Randomized Translational Study to Examine the Effects of Shared Care in Management of Gestational Diabetes
Research question (s)/hypothesis: 1. . The effectiveness of the shared care management of gestational diabetes mellitus; 2. . The cost-effectiveness of the shared care management; 3. . Its sustainability
- Trial name
- NCT01565564
- Testing
- Shared glycaemic control care within the local three-tier's antenatal care network
- Where
- China
- Volunteers
- 948 people
- Sponsor
- Tianjin Women and Children's Health Center
Pre-Gestational Diabetes
IRELAnD: Investigating the Role of Early Low-dose Aspirin in Diabetes
To investigate the effect of aspirin therapy initiated in the first trimester of pregnancy in women with pregestational type I or type II diabetes on a composite clinical measure of placental dysfunction (preeclampsia, preterm…
- Trial name
- IRELAnD (NCT03574909)
- Testing
- Aspirin
- Where
- Ireland
- Volunteers
- 137 people
- Sponsor
- Royal College of Surgeons, Ireland
Diabetes Mellitus in Pregnancy, Diabetes, Gestational
Diabetes in Pregnancy and Pregnancy Outcomes
To compare the clinical, glycemic profile and therapy as well as pregnancy complications and infant mortality among diabetic mothers in Indonesia.
- Trial name
- NCT03602846
- Testing
- Medical Nutrition Therapy, Insulin, Oral Antidiabetics
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Type 2 Diabetes, Gestational Diabetes Mellitus
The Next Generation Longitudinal Birth Cohort Diabetes Study
The overall aim of this project is to understand the independent roles of maternal factors, intrauterine exposures, genetic factors, and postnatal environment on the development of obesity and youth-onset type 2 diabetes (T2D) in…
- Trial name
- NextGen (NCT04621396)
- Testing
- Observational screening study
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Gestational Diabetes Mellitus
Insulin Dependent Gestational Diabetes Mellitus: Randomized Trial of Induction of Labour at 38 and 40 Weeks of Gestation
To evaluate the impact of induction of labour at 38 weeks with the induction of labour at 40 weeks in women with insulin dependent gestational diabetes mellitus on maternal and fetal outcome.
- Trial name
- NCT01256892
- Testing
- induction of labour
- Sponsor
- Medical University of Vienna