Clinical trials: Diabetes Management, active
Diabetes Type 2
Connected Care for Type 2 Diabetes Self-Management
The primary objective of this Randomized Clinical Trial is to improve the self-management (SM) competencies of patients affected by Type 2 Diabetes Mellitus (T2DM) living in the Marche region (Italy) through the support of a…
- Trial name
- RCT_SM (NCT07149610)
- Testing
- M-health solution classified as Class I Medical Devices, equipped with a CE certificate. The m-health solution will be integrated with the EPR currently used by the CADs of the Marche region
- Where
- 11 sites in Italy
- Volunteers
- 388 people
- Sponsor
- Marche Region Regional Health Agency
Diabetic Foot, DFU
Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers
The purpose of this study is to evaluate the efficacy of human placental membrane products and standard of care versus standard of care alone in the management of nonhealing diabetic foot ulcers and venous leg ulcers.
- Conditions
- Diabetic Foot, DFU, Diabetic Foot Ulcer, Foot Ulcer, Diabetic
- Trial name
- BIOCAMP (NCT07089602)
- Testing
- Standard of Care DFU, Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- BioLab Holdings
Diabetes Mellitus, BCG Vaccination Reaction
Diabetes Diagnosis, Management, Prevention and Education in Guinea-Bissau
Type 2 diabetes (T2D) will affect ~650 million adults worldwide by 2040 and about as many will have pre-diabetes. Chronic hyperinsulinemia/insulin resistance precedes T2D development.
- Trial name
- BCGTODM (NCT05591339)
- Testing
- BCG vaccine (two doses, 4 weeks apart)
- Where
- Guinea-Bissau
- Volunteers
- 200 people
- Sponsor
- Bandim Health Project
Type 2 Diabetes
Digital Health Literacy and Diabetes Management in Type 2 Diabetes
This study aims to examine the relationships between digital health literacy, diabetes distress, diabetes self-management, and glycated hemoglobin (HbA1c) levels in individuals with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT07888972
- Where
- Turkey (Türkiye)
- Volunteers
- 348 people
- Sponsor
- Abant Izzet Baysal University
Diabetes Mellitus, Type 2
Lifestyle Management App for Adults With Diabetes Type
This study will evaluate whether the 12-week health coaching mobile application (LIVEN) will succeed in enhancing lifestyle behaviors in adults with Type 2 Diabetes compared to typical treatment.
- Trial name
- LIVEN (NCT05630508)
- Testing
- interactive Mhealth Lifestyle behavior intervention
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Type 2 Diabetes
Effect of Switching From Intermittently Scanned to Real-time Continuous Glucose Monitoring on Diabetes Management in Adults With Type 2 Diabetes (Switch CGM T2D)
The goal of this prospective study is to evaluate diabetes outcomes and patient experience following a switch from second generation intermittently scanned continuous glucose monitor (isCGM) to real-time continuous glucose…
- Trial name
- Switch CGM T2D (NCT06805786)
- Testing
- real-time continuous glucose monitor
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Obesity and Obesity-related Medical Conditions
Efficacy and Safety of Tirzepatide for Weight Management
The goal of this study is to learn if tirzepatide helps people manage their weight safely. It will include adults in Bangladesh who are overweight or obese, with or without type 2 diabetes.
- Trial name
- NCT06918405
- Testing
- Tirzepatide
- Where
- Bangladesh
- Volunteers
- 440 people
- Sponsor
- Chittagong Medical College
Pre Diabetes, Diabetes (DM)
Preventing Diabetes: Impact of an EMR-Based Intervention for Enhanced Pre-Diabetes Management in Primary Care
The goal of this study is to find out if adding electronic medical record (EMR) prompts helps prevent people with pre-diabetes from developing diabetes. It will also look at how these prompts affect doctor and patient behaviors.
- Trial name
- NCT07252700
- Testing
- Electronic Medical Record-Based Clinical Decision Support
- Where
- Singapore
- Volunteers
- 6,000 people
- Sponsor
- Lynette Goh
Type 2 Diabetes Mellitus (T2DM), Pregnancy
CGM for Management of Type 2 Diabetes in Pregnancy
The goal of this clinical trial is to learn if continuous glucose monitoring works better than self-monitoring of blood glucose (fingersticks) to treat type 2 diabetes in pregnancy.
- Trial name
- CGM2 (NCT06628453)
- Testing
- CGM
- Where
- 7 sites in United States
- Volunteers
- 564 people
- Sponsor
- University of Alabama at Birmingham
Hypertension (Without Type 2 Diabetes Mellitus)
Digital Reinforcement of Motivational Interviewing Micro-Skills Among Primary Care Healthcare Professionals
The goal of this clinical trial is to improve hypertensive patients' systolic blood pressure (SBP) through increased application of MI micro-skills by mitigating known implementation barriers through a structured reinforcement…
- Trial name
- NCT07922837
- Testing
- Digital Nudges for Motivational Interviewing (MI) Micro-Skills Reinforcement
- Where
- Singapore
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National University Polyclinics, Singapore
Type 1 Diabetes Mellitus, Diabetes Self-Management Education
DiaBuddy: AI-Enabled Digital Self-Management for Youth With Type 1 Diabetes
The goal of this clinical trial is to learn whether DiaBuddy, a digital self-management app, can help children and adolescents with Type 1 diabetes better manage their condition and reduce the burden experienced by their…
- Conditions
- Type 1 Diabetes Mellitus, Diabetes Self-Management Education, Caregiver Burden
- Trial name
- DiaBuddy (NCT07861373)
- Testing
- DiaBuddy: AI-Enabled Digital Self-Management Intervention, Usual Diabetes Care
- Volunteers
- 140 people
- Sponsor
- Dr. Juwayria Omar
Cardio Vascular Disease, Diabetes (DM)
Holistic CRM Care vs Standard of Care in a Primary Care Setting
Cardiovascular disease, high blood pressure, chronic kidney disease, and type 2 diabetes, collectively referred to as Cardio-Renal-Metabolic (CRM) conditions, are among the most common chronic diseases in society.
- Conditions
- Cardio Vascular Disease, Diabetes (DM), Chronic Kidney Disease
- Trial name
- HOPE-CRM (NCT07819383)
- Testing
- CRM care
- Volunteers
- 6,000 people
- Sponsor
- Danderyd Hospital
Type 2 Diabetes Mellitus (T2DM)
Diabetes Management Using Continuous Glucose Monitors and Remote Patient Monitoring in Underserved Populations
The goal of this 52 week prospective study is to learn whether a Diabetes Care Management Program using a continuous glucose monitor (CGM) and remotely monitoring (RPM) glucose readings can help improve glucose levels and…
- Trial name
- DCMP (NCT06939413)
- Testing
- Continuous glucose monitor (CGM)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Diabetes Solutions International
Diabetes Mellitus, Type 2
Safety, Tolerability, and Effectiveness of Duodenal Mucosal RF Vapor Ablation for Insulin Elimination in Type-2 Diabetes
The purpose of this study is to determine whether RFVA of the duodenal mucosa with or without the combination of Semaglutide is a safe and effective treatment to remove the need for insulin therapy among patients with T2D who are…
- Trial name
- STEAM-IE (NCT06655740)
- Testing
- RF Vapor Ablation
- Where
- Chile
- Volunteers
- 16 people
- Sponsor
- Aqua Medical, Inc.
Type 2 Diabetes
Multimodal Glucose Prediction in Type 2 Diabetes
The primary objective of this research, funded by Samsung Strategic Alliance for Research and Technology, is to develop multi-modal foundation models that integrate Continuous Glucose Monitoring (CGM) data with patient behavior…
- Trial name
- NCT07633171
- Testing
- Digital Health Data Collection System
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johns Hopkins University
Type 2 Diabetes (T2DM)
Clinical Evaluation of Salivary 1,5-Anhydroglucitol in Diabetes
The goal of this observational study is to evaluate the clinical value of salivary 1,5-anhydroglucitol (1,5-AG) and assess a novel noninvasive detection approach in individuals with and without type 2 diabetes.
- Trial name
- NCT07781683
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Shanghai 6th People's Hospital
Healthy Participants
A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
The purpose of this study is to measure the pharmacokinetics (PK-how the body processes the study drug) of elecoglipron in healthy participants when taken by mouth as different formulations.
- Trial name
- NCT07723833
- Testing
- Elecoglipron Reference Formulation Dose A, Elecoglipron Test formulation 1 Dose A, Elecoglipron Reference Formulation Dose B
- Where
- 2 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Diabetes Mellitus Type 2, Diabetes Mellitus Complications
Mobile Health and Wearable Devices for Diabetes Complication Management
The value of intelligent lifestyle intervention for T2D and its complications has been initially explored, but evidence-based support for the effectiveness of related AI risk prediction models and intervention models remains to…
- Trial name
- NCT07129148
- Testing
- Device: No specific devices, Device: CGM,CGM management platform, Device: "Professor Tang" WeChat Mini-program
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Second Xiangya Hospital of Central South University
Type 1 Diabetes
Precision Administration of Anti-thymocyte Globulin With or Without Verapamil
T cell directed therapy, anti-thymocyte globulin (ATG), in low doses, has been shown to lower HbA1c and preserve endogenous insulin production (measured by C-peptide) in individuals with recently diagnosed type 1 diabetes (T1D).
- Trial name
- NCT06455319
- Testing
- Anti-thymocyte globulin (ATG), verapamil extended release capsule
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM)
Population Health Management for KPNC Members With Newly Diagnosed Diabetes: A Randomized Trial of a Proactive and Augmented Initial Care Strategy
This study is a 2-arm randomized trial of Augmented Initial Type 2 Diabetes (T2D) Care vs. Usual Initial T2D Care among adults (18-74 years) with newly diagnosed T2D who have risk factors (defined by age and diagnosis HbA1c…
- Conditions
- Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes (T2D)
- Trial name
- NCT06906653
- Testing
- Augmented Initial Type 2 Diabetes Care
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Kaiser Permanente