Clinical trials: Diabetes Mellitus, Gestational
Type II Diabetes Mellitus, Gestational Diabetes Mellitus
Intrapartum Glycemic Control With Insulin Infusion Versus Rotating Fluids
This study will determine whether rotating intravenous (IV) fluid is better than receiving insulin to control a baby's blood sugar after delivery in laboring women with diabetes.
- Trial name
- NCT03912363
- Testing
- Rotating fluids protocol, Insulin infusion protocol
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Type 2 Diabetes, Gestational Diabetes, Pre-diabetes
Toronto Gestational Glucose Tolerance Cohort
In this prospective observational cohort study, women representing the full spectrum of gestational glucose tolerance status are undergoing longitudinal cardiometabolic characterization at regular intervals in the years after the…
- Trial name
- NCT02583061
- Testing
- There is no intervention. An exposure of interest is glucose tolerance status in pregnancy
- Where
- Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Gestational Diabetes
Late Metabolic Effects of Metformin Therapy in Gestational Diabetes
Metformin in widely used as the treatment of gestational diabetes. However, it is not known whether exposure to metformin in utero has late metabolic effects on the child.
- Trial name
- DIARA2 (NCT02417090)
- Testing
- Insulin, Metformin
- Volunteers
- 173 people
- Sponsor
- Turku University Hospital
Diabetes, Gestational
Continuous Glucose Monitoring for Women With Diabetes Mellitus in the Intrapartum and Postpartum Inpatient Care
Diabetes mellitus affects roughly 8% of pregnancies and is associated with significant perinatal and maternal morbidity. Increasing numbers of women are either entering pregnancy with a continuous glucose monitor (CGM) or are…
- Trial name
- NCT05492890
- Testing
- Dexcom G6
- Volunteers
- 40 people
- Sponsor
- Ohio State University
Inflammation
Effect of Glucose Load on Expression of Advanced Glycation End Products in Women Screened for Gestational Diabetes
The investigator's main objective is to analyze the effects of a routine prenatal care screening tool (glucola test for gestational diabetes) on maternal inflammation through assessment of maternal circulatory biomarkers and…
- Trial name
- NCT03029546
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Long Acting Insulin in Control of Gestational Diabetes Mellitus
Long Acting Insulin Versus Multiple Dose Regimen for Control of Gestational Diabetes Mellitus
multiple dose regimen as a standard treatment for gestational diabetes will be compared to long acting insulin
- Trial name
- NCT04674332
- Testing
- Long acting insulin, multiple dose regimen
- Where
- Egypt
- Volunteers
- 148 people
- Sponsor
- Ain Shams University
Pregnancy, Gestational Diabetes Mellitus, Class A2
Intrapartum Glycemic Control in GDMA2
This is a randomized, parallel, controlled, non-inferiority trial to assess the impact of a tight versus a more liberalized intrapartum glycemic control in gestational diabetic mothers on neonatal glycemia.
- Conditions
- Pregnancy, Gestational Diabetes Mellitus, Class A2, Neonatal Hypoglycemia
- Trial name
- NCT05647798
- Testing
- Blood sugar check every 2 hours, Blood sugar check every 4 hours
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Obesity, Maternal, Gestational Diabetes
Nutrition Optimization and Community Upliftment for Postpartum Recovery
The goal of this clinical trial is to better understand how different strategies, timing, and enhancements to medically tailored food delivery will address structural inequities in the food environment, empower communities to…
- Trial name
- NOURISH-GDM (NCT06445530)
- Testing
- MFeast ENHANCED, MFeast Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Gestational Diabetes, Gestational Hypertension
sFlt-1:PlGF Ratio in Gestational Diabetes: PREDICTION (PREeclampsia in DIabetiC gestaTION) Study
The ratio of soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF) is elevated in pregnant women before the clinical onset of preeclampsia and can be used to predict the preeclampsia.
- Conditions
- Gestational Diabetes, Gestational Hypertension, Pre-Eclampsia
- Trial name
- PREDICTION (NCT04877119)
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Gestational Diabetes
Active Patient GDM
Among women with GDM, the investigators will determine if a strategy of (1) a website-based information and motivational resource bank; (2) biosensor/ePlatform-based physical activity and GWG tracking; and/or (3) a health coach…
- Trial name
- NCT03802877
- Testing
- Resource bank, ePlatform, Health coach
- Where
- 6 sites in Canada
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Gestational Diabetes Mellitus
Home-Ultrasound in Routine High-Risk Care of Patients With Gestational Diabetes Mellitus (GDM)
This study evaluates the impact of incorporating home-ultrasound (home-US) devices into telemedicine care for patients with gestational diabetes mellitus (GDM).
- Trial name
- NCT07158970
- Testing
- Use of the Pulsenmore home ultrasound device for fetal assessment, guided remotely by a physician.
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Wolfson Medical Center
Gestational Diabetes Mellitus
The Effect of Continuous Glucose Monitoring on Glycemic Control in Insulin-requiring Gestational Diabetes Mellitus
The purpose of this study is to determine if professional Continuous glucose monitoring improves glycemic control with less hypoglycaemia in insulin-requiring Gestational Diabetes Mellitus
- Trial name
- NCT02204657
- Testing
- Continuous Glucose Monitoring System
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- University of Malaya
IUGR, Gestational Diabetes
PED NEONAT 20-000599 Fetal Body Composition
Obesity is an ongoing public health problem that is difficult to treat. There is evidence that obesity has fetal origins. Body composition, including visceral, subcutaneous, brown, and hepatic fat have been found to be important…
- Conditions
- IUGR, Gestational Diabetes, Pregnancy Related
- Trial name
- NCT04508751
- Testing
- 3T "Free-Breathing" Fetal Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gestational Diabetes Mellitus
A Mobile Smartphone Application to Promote a Healthy Diet and Physical Activity Among Pregnant Women With GDM - RCT
In this study, the investigators will test a new way to communicate advice on diet and lifestyle to women with gestational diabetes mellitus by app downloaded on women's smartphone.
- Trial name
- NCT02588729
- Testing
- Pregnant+ app for smartphone
- Where
- Norway
- Volunteers
- 238 people
- Sponsor
- Oslo Metropolitan University
Gestational Diabetes Mellitus With Baby Delivered
The MoMMii Study. Diabetes Prevention Intervention on Families With Past Gestational Diabetes
Women with gestational diabetes (GDM) have increased risk of developing type 2 diabetes; their children show more insulin resistance and diabetes compared to offspring of mother without diabetes in pregnancy.
- Trial name
- MoMMii (NCT02343354)
- Testing
- Nutrition/physical activity intervention
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Gestational Diabetes Mellitus (GDM)
STRONG: SMART Trial
Gestational diabetes is a type of diabetes that develops during pregnancy and can increase the risk of health problems for both mothers and babies.
- Trial name
- NCT07920588
- Testing
- STRONG Group Prenatal Care, Usual Prenatal Care, Group-Based Gestational Diabetes Education
- Where
- American Samoa
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Yale University
Gestational Diabetes
Associations of Plasma Fatty Acid Patterns With Gestational Diabetes Mellitus
Background: Limited studies have explored the difference of fatty acid profile between women with and without gestational diabetes mellitus (GDM), and the results were inconsistent.
- Trial name
- NCT05146401
- Testing
- Plasma fatty acid concentration
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- Liegang Liu
Pregnancy, Pregnancy Complications
PregSource: Crowdsourcing to Understand Pregnancy
PregSource uses a crowd-sourcing approach, asking pregnant women to enter information regularly and directly about their pregnancies throughout gestation and the early infancy of their babies into online surveys and trackers via…
- Conditions
- Pregnancy, Pregnancy Complications, Morning Sickness, Diabetes, Gestational
- Trial name
- PregSource (NCT02577536)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 2,359 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Impaired Glucose Tolerance, Fetal Macrosomia
Treatment of Impaired Glucose Tolerance in Pregnancy
The purpose of this study is to evaluate if treatment (insulin or diet) of pregnant women with impaired glucose tolerance (75-g OGTT with a fasting P-gluc <7.0 mmol/l and 2 h P-gluc >10.0 and <12.2 mmol/l) close to normoglycemia…
- Trial name
- TIP (NCT00625781)
- Testing
- Insulin aspart and Insulin human (isophane)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Diabetes Mellitus, Type 2, Gestational Diabetes
Community Health Worker-Led Postpartum Diabetes Screening
Women who experience gestational diabetes are at high risk of developing type 2 diabetes mellitus in the postpartum period-especially in low- and middle-income countries like India where the burden of diabetes is high and…
- Trial name
- NCT06209411
- Testing
- Home Based Testing, Clinic Based Screening, Food order nutritional intervention before meals
- Where
- India
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University