Clinical trials: Diabetes Mellitus, Gestational
Pregnant Women, Gestational Diabetes
Education of Pregnant Women at Risk of Gestational Diabetes
There are studies in the literature showing that there is a decrease in the number of pregnant women diagnosed with gestational diabetes and improvements in parameters related to maternal and infant health, with the education to…
- Trial name
- NCT05568277
- Testing
- Education on preventive health behaviors based on Pender's Health Promotion Model
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Pregnancy Complications, Obesity
Acute Exercise Effects in Obese Pregnancy
Obesity before and during pregnancy is associated with a higher risk for a number of obstetric and metabolic complications in women and their offspring.
- Conditions
- Pregnancy Complications, Obesity, Pre-Eclampsia, Gestational Diabetes
- Trial name
- NCT03750695
- Testing
- Resistance exercise, Aerobic Exercise, Rest
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Gestational Diabetes
Autonomic Nervous Activity in Women With Gestational Diabetes
Through complex hormonal pathways, insulin resistance can lead to the activation of the sympathetic nervous system, and vice versa. Schobel et al.
- Trial name
- NCT00867022
- Where
- Finland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Gestational Diabetes Mellitus
Gestational Diabetes: Insulin or Oral Hypoglycemic Agents?
Gestational diabetes mellitus takes place in 2 steps. First, it is the consequence of insulin resistance due to the modifications of the pregnancy hormonal environment, and second, of the deficiency of the beta cells of the…
- Trial name
- DG5 (NCT01215331)
- Testing
- Insulin, Metformin, glyburide and insulin
- Where
- Canada
- Volunteers
- 73 people
- Sponsor
- Université de Sherbrooke
Metabolic Syndrome, Impaired Glucose Tolerance
Evaluation of Low Source of Signal in SCOUT DS
The overall objective of this study is to increase the number of dark skin tone individuals in the data set and evaluate if this increase in dark skin tone data has an impact on the accuracy of the SCOUT DS Diabetes Risk Score…
- Conditions
- Metabolic Syndrome, Impaired Glucose Tolerance, Gestational Diabetes
- Trial name
- LSS (NCT01339637)
- Where
- 5 sites in United States
- Volunteers
- 196 people
- Sponsor
- VeraLight, Inc.
Gestational Diabetes, Pregnancy Related
Studying Phenotypes of Gestational Diabetes Mellitus in an Asian Pregnant Cohort
Gestational diabetes mellitus (GDM) is a transient hyperglycemic condition identified during pregnancy in women without a history of chronic diabetes.
- Conditions
- Gestational Diabetes, Pregnancy Related, Pregnancy Complications, Birth Weight
- Trial name
- GDM-CARE (NCT06542718)
- Where
- Singapore
- Volunteers
- 800 people
- Sponsor
- National University Health System, Singapore
Obesity, Pregnancy
Maternal Obesity, Breast Milk Composition, and Infant Growth
Today the majority of pregnant women in the United States are either overweight or obese at conception with their offspring having greater adiposity at birth, a 2-fold greater risk of later obesity, and neonatal insulin…
- Conditions
- Obesity, Pregnancy, Breastmilk Collection, Infant Overnutrition
- Trial name
- (MILK) (NCT03301753)
- Where
- 2 sites in United States
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Gestational Diabetes Mellitus (GDM)
Lifestyle Intervention to Prevent the Recurrence of Gestational Diabetes Mellitus
Gestational diabetes mellitus(GDM) is a commom complication during pregnancy and associated with various adverse pregnancy outcomes for both the mother and her offspring.
- Trial name
- NCT03062475
- Testing
- lifestyle intervention with dietary and exercise recommendation
- Where
- China
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Gestational Diabetes, Glucose Intolerance
Postpartum Glucose Tolerance With Levonorgesterel IUD Use in Women With Recent Gestational Diabetes
The study is being done in order to gain information on the most suitable types of birth control in women who recently had gestational diabetes, or diabetes diagnosed during pregnancy.
- Conditions
- Gestational Diabetes, Glucose Intolerance, Type 2 Diabetes, Intrauterine Contraception
- Trial name
- NCT01022645
- Testing
- Mirena (Levonorgestrel IUD), Paragard (Copper IUD ) or Tubal Ligation
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Northwestern University
Gestational Diabetes
Frequency of Blood Glucose Monitoring in Patients With Gestational Diabetes
The incidence of gestational diabetes mellitus (GDM) is increasing. GDM requires patients to test their blood glucose at least four times daily.
- Trial name
- GLIMPSE (NCT01818557)
- Testing
- Blood glucose testing
- Where
- 3 sites in United States
- Volunteers
- 293 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gestational Diabetes
The Effect of Steroids on Maternal Glucose Levels
This study will look at blood sugar levels in pregnant women who have been given a glucocorticoid (steroid) medication to enhance fetal lung maturity.
- Trial name
- NCT03021837
- Testing
- antenatal corticosteroid
- Volunteers
- 200 people
- Sponsor
- St. Louis University
Gestational Diabetes Mellitus (GDM)
Preventive Effect of Probiotics in GDM
Gut microbiota is instrumental in the microbial and metabolic network of pregnant women, and is potentially related with gestational diabetes.
- Trial name
- NCT06938464
- Testing
- Probiotics
- Where
- China
- Volunteers
- 334 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Gestational Diabetes Mellitus (GDM)
SFEE Diet Management for Gestational Diabetes Mellitus
This study aims to evaluate the impact of the Self-Family-Environment Empowerment (SFEE) diet management intervention on glycemic control, maternal outcomes, and dietary adherence in pregnant women with gestational diabetes…
- Trial name
- SFEE (NCT06707064)
- Testing
- SFEE Diet Management Intervention, Standard Dietary Advice
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Ji Jing
Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy
Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes
The effects of consuming non-nutritive sweeteners (NNS) during pregnancy and lactation on infant obesity and cardiometabolic disease risk are not well understood.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy, Non-nutritive Sweeteners Consumption in Pregnancy and/or Lactation
- Trial name
- NCT06548828
- Testing
- NNS Restriction Intervention, Control Intervention
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- George Washington University
GDM
Efficacy of Lactobacillus Rhamnosus LRa05 in Gestational Diabetes
This study aims to comprehensively evaluate the multifaceted impacts of Lactobacillus rhamnosus LRa05 on patients with gestational diabetes.
- Trial name
- NCT06901791
- Testing
- Conventional treatment and Probiotic
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Gestational Diabetes Mellitus
A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus
Rationale Gestational diabetes mellitus (GDM) complicates 5-7% of pregnancies. Major hazards include macrosomia, polyhydramnios, labor trauma and neonatal hypoglycemia.
- Trial name
- NCT01563120
- Testing
- metformin, glybenclamide
- Where
- Israel
- Volunteers
- 108 people
- Sponsor
- HaEmek Medical Center, Israel
Gestational Diabetes, Insulin Resistance
Pregnancy Outcomes: Effects of Metformin Study (POEM Study)
One approach to prevent the rising burden of diabetes is to address the issue of gestational diabetes mellitus (GDM). GDM has a growing prevalence up to 5-10% (and even higher in specific subgroups), with a pregnant population…
- Trial name
- POEM (NCT02947503)
- Testing
- Metformin TEVA 850 mg
- Where
- 4 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Bethesda Diabetes Research Center
Gestational Diabetes Mellitus (GDM)
Insulin Resistance in Gestational Diabetes Mellitus
This prospective cohort study investigates glycaemic variability, assessed by continuous glucose monitoring (CGM), in pregnant women with gestational diabetes mellitus (GDM) and its association with fetal growth and related…
- Trial name
- IRIS (NCT07231341)
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Gestational Diabetes
Visualizing Beta Cells in Patients With a History of Gestational Diabetes
In order to evaluate the difference in beta cell mass in women with and without a history of gestational diabetes mellitus (GDM), investigators aim to compare quantitative PET imaging of the pancreas between these groups.
- Trial name
- NCT03182296
- Testing
- 68Ga-NODAGA-exendin-4 PET/CT
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Gestational Diabetes
Oral Antidiabetic Agents in Pregnancy
The aim of this study is to determine the efficacy of oral treatment with glyburide and metformin controlling excessive fetal growth in women with gestational diabetes, using insulin as a ransom on no response to oral treatment .
- Trial name
- NCT02091336
- Testing
- Metformin, Glyburide
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre