Clinical trials: Diabetes Mellitus, Type 1, Type 2
Kidney Failure, Chronic, Diabetes Mellitus, Type 1
Vascular Reactivity in Kidney Disease Patients
Dialysis patients suffer from many problems with blood vessels and this is even more so for patients with the added complication of diabetes.
- Conditions
- Kidney Failure, Chronic, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00226902
- Testing
- Changing hemoglobin concentration
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Melbourne Health
Type I Diabetes Mellitus With Ulcer, Type II Diabetes Mellitus With Ulcer
Safety Study of Stem Cells Treatment in Diabetic Foot Ulcers
Diabetes Mellitus (DM) can be regarded as one of the "epidemics" of the western world. DM contributes to severe morbidity and mortality due to damage in the target organs (neuropathy, vasculopathy, nephropathy, retinopathy).
- Trial name
- NCT01686139
- Testing
- ABMD-MSC
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Sheba Medical Center
Type 2 Diabetes Mellitus
Safety and Efficacy of Sitagliptin Compared With Glimepiride in Elderly Participants With Type 2 Diabetes Mellitus (MK-0431-251)
The primary objectives of this study are to determine if sitagliptin treatment is not inferior to that of glimepiride as measured by the change in baseline hemoglobin A1C (HbA1C) after 30 weeks of treatment, and if sitagliptin…
- Trial name
- NCT01189890
- Testing
- sitagliptin phosphate, Glimepiride
- Volunteers
- 480 people
- Sponsor
- Merck Sharp & Dohme LLC
Type 1 Diabetes
PK/PD Study of Intranasal Insulin in Type I Diabetes
This study is designed to compare the safety and tolerability of two different doses of intranasally administered regular human insulin with those of a single dose of the rapid-acting insulin analog lispro Humalog® after…
- Trial name
- NCT01201278
- Testing
- Insulin, Insulin LISPRO
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hompesch, Marcus, M.D.
Type 1 Diabetes Mellitus
Evaluation of Virtual Versus Traditional Study Conducted in a Group Pilot Study in Adult Patients With Type 1 Diabetes Mellitus (eStudy)
Primary Objective: To evaluate the effect of virtual approach via novel technologies versus traditional study conduct on glycemic control in terms of glycated hemoglobin (HbA1c).
- Trial name
- NCT03260868
- Testing
- Insulin glargine, 300 units per milliliter (U/mL), Background therapy: Rapid Acting meal time insulin analogs (Humalog, Novolog or Apidra)
- Where
- 6 sites in United States, Canada
- Volunteers
- 15 people
- Sponsor
- Sanofi
IgA Nephropathy, CKD Associated With Type 1 Diabetes
A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX
This multi-center, open-label Phase 2 trial will study the safety, tolerability, and efficacy of bardoxolone methyl in qualified patients with the following rare chronic kidney diseases (CKD): CKD associated with type 1 diabetes…
- Conditions
- IgA Nephropathy, CKD Associated With Type 1 Diabetes, Focal Segmental Glomerulosclerosis, Autosomal Dominant Polycystic Kidney
- Trial name
- PHOENIX (NCT03366337)
- Testing
- Bardoxolone methyl capsules
- Where
- 30 sites in United States
- Volunteers
- 103 people
- Sponsor
- Biogen
Diabetes Mellitus Type 2, Diabetes Mellitus Type 1, NAFLD - Nonalcoholic Fatty Liver Disease
Kuwait Adult Diabetes Epidemiological Multidisciplinary (KADEM) Program
Kuwait and the Gulf Region lack large longitudinal studies that identify risk factors dictating the onset of prediabetes and the progression to diabetes.
- Conditions
- Diabetes Mellitus Type 2, Diabetes Mellitus Type 1, NAFLD - Nonalcoholic Fatty Liver Disease, PreDiabetes
- Trial name
- KADEM (NCT06115876)
- Where
- Kuwait
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Dasman Diabetes Institute
Primary Disease: 1. Type 2 Diabetes
Culinary Medicine vs. Nutrition Education in Diabetes
This pragmatic trial compares the effectiveness of virtual culinary medicine classes vs. standard of care medical nutrition visits to improve glycemic control in patients with uncontrolled type 2 diabetes .
- Trial name
- NCT05019274
- Testing
- Culinary Medicine Intervention, Standard of Care Nutrition Visits
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Gestational Diabetes, Diabetes Mellitus, Type 2
Decrease Type II Diabetes in Gestational Diabetes Population
The goal of the study is to examine the impact of an educational video on the rate of breastfeeding in mothers who had gestational diabetes mellitus, and the rate of type-II diabetes mellitus diagnosed postpartum.
- Conditions
- Gestational Diabetes, Diabetes Mellitus, Type 2, Breastfeeding, Diabetes Mellitus, Type 1
- Trial name
- NCT05202002
- Testing
- Video clip, No video clip
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Diabetes Mellitus, Type 2, Food Insecurity
Food Insecurity Reduction & Strategy Team
This study seeks to address the multifaceted challenges posed by food disparities and their negative consequences on health outcomes, via a comprehensive community health intervention program. Study objectives include: 1.
- Conditions
- Diabetes Mellitus, Type 2, Food Insecurity, Diabetes Mellitus, Type 1
- Trial name
- FIRST (NCT06329375)
- Testing
- Nutrition program
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Stanford University
Diabete Type 1, Diabete Type 2
VOIES-D-ql - Qualitative Study on Experiences of Diabetes Care Delivery and Planning
Population aging and the increase in incidence and prevalence of potentially disabling chronic conditions make health care more and more complex and costly.
- Trial name
- VOIES-D-ql (NCT04217902)
- Testing
- Description of patients' experiences of diabetes care delivery and planning, Description of health care professionals needs and experiences in diabetes care delivery and planning
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Hospices Civils de Lyon
Diabetes Mellitus, Type 2
Phenotypic and Genetic Correlates of Diabetes (Non-Type 1) in Young Non-Obese Asian Indians in North India and A Study to Evaluate the Efficacy of Sitagliptin (DPP-4 Inhibitor) in a Sub-group of the Study Population
This is a phase IV study of 3.5 years duration to evaluate the phenotypic and genetic correlates of diabetes (non-Type 1 in young non-obese Asian Indians in North India and pilot case control study to evaluate the efficacy of…
- Trial name
- NCT00964184
- Testing
- Metformin, Lifestyle modification
- Where
- India
- Volunteers
- 133 people
- Sponsor
- Diabetes Foundation, India
Type 1 Diabetes (T1D), Type 2 Diabetes
Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery
The goal of this randomized controlled trial is to compare the efficacy and safety of the iLet Bionic Pancreas (BP) System in adults with insulin-treated diabetes (type 1 diabetes or type 2 diabetes) compared to standard of care…
- Conditions
- Type 1 Diabetes (T1D), Type 2 Diabetes, Diabetes, Autoimmune, Diabetes Mellitus
- Trial name
- PREPARE 4 AID (NCT07011147)
- Testing
- Bionic Pancreas, Routine Care
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- University of Colorado, Denver
Diabetes, Diabete Type 2
Use of a Smart-phone Based Medication Adherence Platform to Improve Outcomes in Uncontrolled Non-insulin Dependent Diabetes Among Veterans
The purpose of this study is to determine if a novel smartphone-based medication adherence platform accompanied by directed pharmacist intervention can improve A1c control and medication compliance in non-insulin dependent…
- Trial name
- NCT05789706
- Testing
- Dayamed Arthur a novel intelligent medication adherence platform
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Sierra Nevada Health Care System
Type 2 Diabetes Mellitus
Absolute Bioavailability Study With Bexagliflozin
The purpose of this study is to determine the absolute bioavailability of bexagliflozin following a single oral dose co-administered with an intravenous dose.
- Trial name
- NCT03417076
- Testing
- Bexagliflozin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Theracos
Type 2 Diabetes, Type 1 Diabetes
Dark Chocolate and Glucose Levels in Diabetes
Diabetes is a growing concern in the world with an estimated 9.3% of adults, ages 20-79, with it in 2019, type 2 diabetes accounting for 90% of this total.
- Trial name
- NCT04847999
- Testing
- Dark chocolate
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of British Columbia
Type 2 Diabetes Mellitus
Vascular Function and Biomarker Assessments in Healthy Volunteers and in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the vascular function and biomarkers in healthy volunteers and type 2 diabetic patients.
- Trial name
- NCT04744636
- Testing
- Other
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institut de Recherches Internationales Servier
Type 2 Diabetes Mellitus
Study Evaluating Rimonabant Efficacy in Insulin-Treated Diabetic Patients(ARPEGGIO)
Primary: Effect on HbA1c over 48 weeks in insulin-treated patients with type 2 diabetes Secondary: Effect on glucose, total daily insulin dose, body weight, waist circumference, HDL-cholesterol, triglycerides - Safety…
- Trial name
- NCT00288236
- Testing
- Rimonabant (SR141716)
- Where
- 12 sites in United States, Argentina and 10 more
- Volunteers
- 368 people
- Sponsor
- Sanofi
Diabetes, Diabetes Mellitus, Type 1
Impact of Two Medtronic Infusion Sets on Lipohypertrophy in Type 1 Diabetes (T1DM) Patients Thought to Have LH
This is an observational study using ultrasound (US) and palpation to assess the impact of infusion sets on lipohypertrophy (LH) in an infusion set crossover study.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Lipohypertrophy
- Trial name
- NCT06074965
- Testing
- Medtronic Extended Infusion Set
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Azienda Ospedaliera San Camillo Forlanini
Patients
Drug Interaction Study Between Dorzagliatin and Empagliflozin
This is a Phase 1, open-label, sequential, multiple-dose, drug interaction study of glucokinase activator dorzagliatin and empagliflozin in subjects with T2DM.
- Trial name
- NCT03790787
- Testing
- Empagliflozin, Dorzagliatin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Hua Medicine Limited
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