Clinical trials: Diabetes Mellitus, Type I
Type 1 Diabetes
An 8-Day Initiation of Advanced Hybrid Closed Loop System In Children and Adolescents
One of the available Hybrid closed loop system is MiniMed 670G (Medtronic Diabetes, Northridge, CA, USA), which is indicated for children above 7 years old, adolescents and adults with Type 1 Diabetes.
- Trial name
- NCT04509362
- Testing
- Advanced Hybrid Closed Loop System
- Where
- Qatar
- Volunteers
- 34 people
- Sponsor
- Sidra Medicine
Type 1 Diabetes Mellitus, Fear of Hypoglycemia
Fear of Hypoglycemia in Children and Adolecents With Type 1 Diabetes
Acute symptoms of hypoglycemia influence all aspects of every day life and reduce quality of life of children and adolescents with type 1 diabetes and their parents.
- Trial name
- NCT04454827
- Where
- Slovenia
- Volunteers
- 316 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
Continuous Glucose Monitoring, Type 1 Diabetes
Inter-Arm Differences in Continuous Glucose Monitor Readings in Adults With Diabetes
This is a clinical trial looking at differences in continuous glucose monitor (CGM) glucose readings between the left and right arms in adults with type 1 or type 2 diabetes.
- Conditions
- Continuous Glucose Monitoring, Type 1 Diabetes, Type 2 Diabetes
- Trial name
- NCT07920341
- Testing
- FreeStyle Libre 3 Plus Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of the Pacific
Type1 Diabetes Mellitus
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study)
Type 1 diabetes (T1D) results from destruction of insulin-producing beta cells in the pancreas by the body's own immune system (autoimmunity).
- Trial name
- EXE-T1D (NCT03369821)
- Testing
- Beta Cell Loss and Immune Function, Immune Function with RNAseq
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 300 people
- Sponsor
- University of Exeter
Type 1 Diabetes
BABYDIET-Study - Primary Prevention of Type 1 Diabetes in Relatives at Increased Genetic Risk
The major goals of this project are to determine whether primary intervention through delayed introduction of dietary gluten is feasible and could reduce the incidence of islet autoimmunity in high-risk first degree relatives of…
- Trial name
- NCT01115621
- Testing
- Glutenfree diet during the first year of life
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Institut fur Diabetesforschung, Munich, Germany
Diabetes, Diabetes Mellitus, Type 1
A Trial Investigating the Effect of NN1250 in Japanese Subjects With Type 1 Diabetes
This trial is conducted in Japan. The aim of this clinical trial is to investigate the effect of NN1250 (insulin degludec) in Japanese subjects with type 1 diabetes.
- Trial name
- NCT01135927
- Testing
- insulin degludec, insulin detemir
- Where
- Japan
- Volunteers
- 22 people
- Sponsor
- Novo Nordisk A/S
Coronary Artery Calcification
Toe-brachial Index and Coronary Calcification in Type 1 and 2 Diabetes
Diabetes is not a coronary risk equivalent, despite cardiovascular disease is the most common cause of death in diabetes. So, to identify diabetic patients at high cardiovascular risk is necessary.
- Trial name
- ACCoDiab (NCT03920683)
- Testing
- Data collection
- Where
- France
- Volunteers
- 707 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 1 Diabetes, Adolescent
Roy Adaptation Model in People With Type 1 Diabetes
The study was conducted to determine the effect of Roy adaptation model-based education on disease compliance and metabolic control in adolescents with Type 1 diabetes.
- Trial name
- NCT05336929
- Testing
- Roy adaptation model-based nursing education
- Volunteers
- 60 people
- Sponsor
- Balikesir University
Type I Diabetes
Immunosafety Study of Recombinant Human Insulins in Type 1 Diabetics
This is an open label, randomized, parallel group comparison of the immunogenicity safety of Wockhardt's human insulin and isophane insulin compared with the Novo Nordisk's yeast based human insulin products (marketed in USA) in…
- Trial name
- NCT01308437
- Testing
- Wosulin (N or 70/30 with R), Novolin® (N or 70/30 with R)
- Where
- 25 sites in United States, India
- Volunteers
- 134 people
- Sponsor
- Wockhardt
Diabetes Mellitus Type 1
The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas
This study will compare two different models of a wearable bionic pancreas device (the iPhone-based bionic pancreas vs. the iLet bionic pancreas) in adult participant with type 1 diabetes.
- Trial name
- NCT02701257
- Testing
- iPhone bionic pancreas, iLet bionic pancreas, Xeris Xerisol glucagon
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Type 1 Diabetes Mellitus
Characterization of Type 1 Diabetes Subgroup: An Artificial Intelligence Analysis of Clinical and Glucometric Features
The goal of this observational study is to characterize different subgroups among patients with type 1 diabetes. The main research question is: Are there distinct subtypes among people with type 1 diabetes? Participants will be…
- Trial name
- T1DC (NCT07461805)
- Where
- Spain
- Volunteers
- 800 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Diabetes Mellitus, Type 1
Pre Transplant Rapamycin Treatment in Islet Transplantation Alone
Numerous changes to the original Edmonton protocol have been proposed in the attempt of improving the still unsatisfactory long-term function of ITA.
- Trial name
- ITA-Rp (NCT01060605)
- Testing
- rapamycin
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- IRCCS San Raffaele
Type 1 Diabetes (T1D)
CKM For Safe Use of SGLT2i in Type 1 Diabetes
This research study is being conducted to learn if wearing a combination continuous glucose monitor/continuous ketone monitor (CGM/CKM) can reduce the side effects of taking sotagliflozin (study drug) in people with type 1…
- Trial name
- NCT07211802
- Testing
- Sotagliflozin Low Dose, Sotagliflozin High Dose, Dual Continuous Glucose and Ketone Monitor
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, San Diego
Diabetes Mellitus, Type 1, Type 1 Diabetes Mellitus
Treatment of Diabetic Neuropathy With Liraglutide
The purpose of this trial is to explore whether liraglutide has a long term effect on clinical symptoms and biomarkers in patients with diabetic neuropathy.
- Trial name
- TODINELI (NCT02138045)
- Testing
- Liraglutide treatment
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Aalborg University Hospital
Diabetes Mellitus, Type 1
Diabetic Patients Needs in Therapeutic Education About Work. TE-DIW (Therapeutic Education of DIabetic Working People)
Diabetes mellitus is an important disease around the world and the number of diabetic people increase every day. The type 1 diabetes often occurred in the youth and people have to learn to work with it and its complication.
- Trial name
- ET-DIT (NCT03893266)
- Testing
- Interviews
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Type 1 Diabetes
Evaluation of Long-Term Implanted Sensor in Patients on Quality of Life
Evaluation of Long-Term Implanted Sensor in Patients on Quality of life
- Trial name
- NCT04161651
- Testing
- eversense
- Volunteers
- 22 people
- Sponsor
- Meir Medical Center
Type 2 Diabetes, Men
PowerUp for Health: A Diabetes Prevention Program for Men
The purpose of this two-year proposal is to: 1. develop and 2. complete a pilot test of an adaptation of the evidence-based National Diabetes Prevention Program (NDPP) tailored to engage men with prediabetes in disadvantaged…
- Trial name
- NCT02555631
- Testing
- lifestyle
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Type 1 Diabetes
Validation of the Artificial Pancreas Diabeloop Algorithm in the Hospital
To assess whether the DIABELOOP algorithm provides better glycemic control than the usual algorithm of T1D patients on pump therapy: at meals, with CHO roughly assessed by the patient.
- Trial name
- WP6-1 (NCT02101229)
- Testing
- Insulin, Asp(B28)-
- Where
- 3 sites in France
- Volunteers
- 17 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Gingivitis, Periodontal Diseases
Gingival Health and Malocclusion Among Type 1 Diabetic Children and Adolescents
Introduction: This study aims to evaluate the gingivitis, periodontal profile and malocclusion in children and adolescents with diabetes.
- Conditions
- Gingivitis, Periodontal Diseases, Diabetes, Diabetes Mellitus, Type 1
- Trial name
- NCT06291129
- Testing
- Periodontal therapy
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Diabetes Mellitus, Type 1
Optimizing Metabolic Control in Type 1 Diabetes - The Automatic Bolus Calculator Flash Study
This study aims to compare the effect of flash glucose monitoring (FGM) with traditional self-monitoring of blood glucose (SMBG) with or without carbohydrate counting and automated bolus calculation, in patients with type 1…
- Trial name
- NCT03682237
- Testing
- Carbohydrate counting, automated bolus calculation, Flash glucose monitoring (FGM)
- Where
- Denmark
- Volunteers
- 184 people
- Sponsor
- Steno Diabetes Center Copenhagen
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