Clinical trials: Diabetes Mellitus, Type I
Diabetes Mellitus, Type 1
Pharmacist Led Educational Intervention on QOL, Medication Adherence & Satisfaction on Patients With Type 1 DM
There was no previous study in Iraq to evaluate the efficacy of pharmacist-led educational intervention on patient glycemic control, quality of life and medication adherence among type 1 diabetic patients in Iraq.
- Trial name
- NCT06547970
- Testing
- Educational intervension
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Baghdad
Type 1 Diabetes Mellitus, Hypoglycemia
MGA031, Sirolimus and Tacrolimus in Islet Transplantation
This clinical trial is designed to extend the observations made in our pilot clinical trial (IND 8971, Study #1) on the safety and efficacy of immunotherapy with the anti-CD3 monoclonal antibody hOKT3γ1 (Ala-Ala), (currently…
- Trial name
- NCT00265473
- Testing
- Allogeneic Islets of Langerhans
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Minnesota
Type 1 Diabetes
GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab
The goal of this study is to determine how a drug class called glucagon-like peptide-1 receptor agonists (GLP-1Ra) affects people during an early stage of Type 1 Diabetes undergoing clinical teplizumab treatment.
- Trial name
- GLP-TEP (NCT06338553)
- Testing
- Semaglutide (Rybelsus®)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanderbilt University Medical Center
Diabetes Mellitus, Type 1, Insulin Hypoglycemia
Effects of Frequency and Duration of Exercise in People With Type 1 Diabetes A Randomized Crossover Study
According to the Standards of Medical Care in Diabetes by the American Diabetes Association, people with diabetes should aim for 30 minutes of moderate-to-vigorous intensity aerobic exercise at least 5 days a week or a total of…
- Trial name
- NCT04089462
- Testing
- "Five sessions per period" - "Two sessions per period", "Two sessions per period" - "Five sessions per period"
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Steno Diabetes Center Copenhagen
Type 1 Diabetes
Time Limited Eating in Type 1 Diabetes
This study is a randomized-control pilot study that aims to evaluate Time Limited Eating (TLE) in the pediatric T1D population, implemented within the first six months after diagnosis.
- Trial name
- TLET1D (NCT05031429)
- Testing
- Time Limited Eating
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Children's Hospital Los Angeles
Diabetes Mellitus, Type 1
Early Feasibility Study 2 of Outpatient Control-to-Range - Testing System Efficacy (France)
An unblinded, randomized, cross-over design with each patient participating in two 40-hour outpatient admissions: (a) Experimental involving automated Control-to-Range (CTR) and (b) Control using Continuous Glucose Monitor…
- Trial name
- NCT01742741
- Testing
- Diabetes Assistant (DiAs)
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University of Virginia
Type 1 Diabetes Mellitus
Flexible Insulin Therapy Untethered Insulin Regimen in Avidly Exercising Patients With Type 1 Diabetes: FIT Untethered
The overall objective of this study is to evaluate glycemic control and patient-reported outcomes in patients with Type 1 diabetes (T1D) who use insulin degludec and continuous subcutaneous insulin infusion in a combination…
- Trial name
- FIT Untethered (NCT03838783)
- Testing
- Insulin Degludec
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Type1diabetes, Metabolic Syndrome
The Effect of Exercise on Metabolic Parameters, Anthropometric Measurement Values and Quality of Life
This study was planned as a randomized controlled experimental study to determine the effect of exercise with Augmented Reality Glasses (AR) on metabolic parameters, anthropometric measurement values and quality of life in…
- Conditions
- Type1diabetes, Metabolic Syndrome, Nursing Caries
- Trial name
- NCT05737654
- Testing
- Exercise with augmented reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- TC Erciyes University
Type 1 Diabetes
Incretin Effect and Use After Clinical Islet Transplantation
We aim to study if the administration of medications to increase the secretion of hormones from the intestines can improve glycemic control, reduce insulin use and promote β-cell regeneration/expansion in subjects with type 1…
- Trial name
- NCT00768651
- Testing
- Pantoprazole, Sitagliptin
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Alberta
Diabetes Mellitus, Type 1
Keeping in Touch (KiT) With Youth as They Transition to Adult Type 1 Diabetes Care
The investigators are testing the effectiveness of an eHealth digital tool co-designed with patients and providers to improve diabetes self-efficacy in young adults as they transition to adult type 1 diabetes care.
- Trial name
- KiT (NCT05434754)
- Testing
- eHealth Tool
- Where
- 6 sites in Canada
- Volunteers
- 234 people
- Sponsor
- The Hospital for Sick Children
Type 1 Diabetes
Happy Bob App: A Preliminary Evaluation of Its Use in Youth With Diabetes
The goal of this clinical trial is to evaluate the impact of peer support via the Happy Bob phone app in youth with Type 1 Diabetes.
- Trial name
- NCT06412601
- Testing
- RPM, app
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Diabetes Mellitus, Type 1
Study to Evaluate Safety and Efficacy of IBsolvMIR in Islet Transplantation
This is a Phase II open, randomized, active comparator-controlled multi center study in patients with severe type-1 diabetes. This is a two-armed study where patients are randomized in a 2:1 ratio between IBsolvMIR and heparin.
- Trial name
- NCT03867851
- Testing
- IBsolvMIR, Heparin
- Where
- 5 sites in Netherlands, Norway and 1 more
- Volunteers
- 7 people
- Sponsor
- TikoMed AB
Type 2 Diabetes Mellitus
A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics After High Single Ascending Oral Doses of AZD1656 in T2DM Patients
The purpose of this study is to investigate safety and tolerability after high Single Ascending Oral Doses of AZD1656.
- Trial name
- NCT01221545
- Testing
- AZD1656
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 1
A Study of SIMPONI® to Arrest Beta-cell Loss in Type 1 Diabetes
The primary purpose of this study is to determine if golimumab can preserve beta-cell function in children and young adults with newly diagnosed Type 1 Diabetes (T1D).
- Trial name
- T1GER (NCT02846545)
- Testing
- Golimumab
- Where
- 33 sites in United States
- Volunteers
- 84 people
- Sponsor
- Janssen Research & Development, LLC
Type 1 Diabetes, Sleep Apnea Syndrome
Sleep Apnea in Type 1 Diabetes
Sleep apnea syndrome is strongly associated to type 2 diabet, partly and this is partly due to obesity. Treatment of sleep apnea may improve hypertension, cardiovascular risk and in some studies diabetes status.
- Trial name
- DIASOM (NCT01935765)
- Testing
- Polysomnography, Evaluation of the autonomous nervous system, Clinical examination of the sleep
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes, Diabetes Mellitus, Type 1
Efficacy and Safety of Liraglutide in Subjects With Type 1 Diabetes Undergoing Islet Cell Transplantation
This trial is conducted in Europe and North America. The aim of this trial is to investigate if liraglutide treatment can increase the proportion of insulin-independent subjects one year after islet cell transplantation who…
- Trial name
- NCT01206101
- Testing
- liraglutide
- Where
- 16 sites in United States, Canada and 4 more
- Volunteers
- 3 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes Mellitus
Structured Carbohydrate-Counting Education in Adults With Type 1 Diabetes
This study evaluated changes in glycemic outcomes following a structured carbohydrate-counting education program in adults with type 1 diabetes using continuous glucose monitoring (CGM).
- Trial name
- NCT07834801
- Testing
- Carbohydrate counting education
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Acibadem University
Diabetes Mellitus, Type 1
Interventions to Prevent Adolescents With Type 1 Diabetes From Long-term Complications
The purpose of this study is to evaluate the effectiveness of diabetes management training combined with the method of Motivational Interviewing with elements of Cognitive Behaviour Therapy and E-mail support in the treatment of…
- Trial name
- NCT01520428
- Testing
- Motivational Interviewing, CBT and E-mail support
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Type 1 Diabetes
The Management of Glucose Control and Hypoglycemic Prevention Using Continuous Glucose Monitoring System in Patients With Type 1 Diabetes
This study was designed to evaluate the glucose control and hypoglycemic prevention effect of using continuous glucose monitoring system(CGMS) in patients with type 1 diabetes.
- Trial name
- NCT04684030
- Testing
- Continuous glucose monitoring system(CGMS), Self-monitoring of blood glucose (conventional fingerpricking method)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Diabetes Mellitus, Type 2, Metformin Adverse Reaction
Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex I
Metformin is associated with a high degree of gastrointestinal intolerance, which limits the effective use of the medication. It is proposed to be an inhibitor of liver mitochondrial glycerophosphate dehydrogenase which results…
- Trial name
- NCT03445702
- Testing
- Metformin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- St. Louis University
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