Clinical trials: Diabetes Mellitus, Type I
Biomarkers, Saliva
Application of Salivary Biomarkers in Risk Assessment for Oral Diseases in Children With Type 1 Diabetes
This research contributes to a deeper understanding of the etiopathogenesis of periodontal and other oral diseases in children with T1D.
- Conditions
- Biomarkers, Saliva, Type 1 Diabetes (T1D), Dental Care for Children
- Trial name
- NCT06924372
- Testing
- Taking saliva samples of unstimulated saliva will be collected in sterile containers, salivets., Dental status, Periodontal status
- Where
- Serbia
- Volunteers
- 112 people
- Sponsor
- University of Novi Sad
Type 1 Diabetes
A Study to Assess the Effects of CT-868 Treatment on Glucose Homeostasis in Participants with Type 1 Diabetes
This study will be conducted primarily to evaluate the effects of CT-868 on glucose homeostasis in participants with Type 1 Diabetes Mellitus.
- Trial name
- NCT05794581
- Testing
- CT-868, Victoza
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Carmot Therapeutics, Inc.
Type 2 Diabetes
Influence of Endothelial Function on Central and Peripheral Causes Of Exercise Impairment in Type 2 Diabetes
This study will evaluate the effects of impaired blood flow regulation on exercise. It will also determine whether the effects are more important in the heart or in the skeletal muscle tissue during exercise.
- Trial name
- InsITE (NCT00786019)
- Testing
- Exercise program, Ascorbic Acid (Vitamin C)
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type 1 Diabetes
Acetazolamide in Persons With Type 1 Diabetes - Crossover Trial
The goal of this study is to learn about the effect of the study drug acetazolamide in individuals with Type 1 Diabetes. Specifically, whether acetazolamide provides benefits to the kidneys while minimizing any side effects of…
- Trial name
- NCT06981234
- Testing
- Acetazolamide
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Diego
Type 1 Diabetes Mellitus, Physical Activity
Physical Activity in Children With Type 1 Diabetes Study
This study aims to test the feasibility of a physical activity intervention called the Steps To Active Kids (STAK) programme in children aged 9 - 11 years with Type 1 Diabetes Mellitus (T1DM).
- Trial name
- NCT02144337
- Testing
- Steps To Active Kids (STAK) programme
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Nottingham
Type 1 Diabetes
Short Term Closed-loop Glucose Control in Adults With Type 1 Diabetes
The main objective of this study is to determine the feasibility, efficacy and safety of automated closed-loop glucose control in the home setting over a short term period.
- Trial name
- AP@home02 (NCT01666028)
- Testing
- FlorenceD or similar closed loop glucose control system, CSII with real-time CGM
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 18 people
- Sponsor
- University of Cambridge
Retinal Vascular, Retinal Disease
Perifoveal Vascular Network Assessed by OCT-Angiography in Type I Diabetes Mellitus
This study is directed to evaluate the role of Optical Coherence Tomography Angiography (OCT-A) in the evaluation of the perifoveal vascular network in type 1 diabetic patients, and to investigate the relationship between…
- Conditions
- Retinal Vascular, Retinal Disease, Retinal Ischemia, Retinal Ischaemia Due to Type 1 Diabetes Mellitus
- Trial name
- NCT03422965
- Testing
- Optical Coherence Tomography Angiography, Blood test, Urine test
- Where
- 2 sites in Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Diabetes Mellitus, Type 1
A Study to See the Effect of NNC0194-0499 Alone or in Combination With Semaglutide on Blood Sugar Control in People Living With Type 1 Diabetes
This study is testing the effect of a new study medicine NNC0194-0499 in type 1 diabetes. The purpose of the study is to compare the effect of NNC0194-0499 on the blood sugar levels of participants with type 1 diabetes when taken…
- Trial name
- NCT07087795
- Testing
- NNC0194-0499, Semaglutide
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus Type 1, Remission of Type 1 Diabetes
The Influence of Partial Remission Phase of Type 1 Diabetes on Patient Outcome
Natural course of diabetes mellitus involves gradual reduction of β cell mass within islets of Langerhans in the pancreas. Symptoms of diabetes present when the mass of insulin-producing cells reaches a point where insulin…
- Conditions
- Diabetes Mellitus Type 1, Remission of Type 1 Diabetes, Chronic Complications of Diabetes
- Trial name
- POZREM (NCT02220257)
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Poznan University of Medical Sciences
Diabetes Mellitus, Type 1, Diabetes
The T1D Exchange Registry
The T1D Exchange Registry is a research study, conducted over time, for individuals with type 1 diabetes and their supporters. Participants volunteer to provide their data for research (for example, by answering questions in…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes, Type 1 Diabetes, Diabetes Mellitus
- Trial name
- T1D Registry (NCT04629586)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- T1D Exchange, United States
Type 1 Diabetes
Islet Transplantation in Type 1 Diabetic Patients
Our hypothesis is that a successful clinical islet transplant program can be established at the University of Wisconsin using a steroid -free, sirolimus- and low dose tacrolimus - based immunosuppressive drug regimen (Edmonton…
- Trial name
- NCT00214253
- Testing
- Thiazolidinedione
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Wisconsin, Madison
Type 1 Diabetes
Resistance Training in Type 1 Diabetes Mellitus
The purpose of this study is to learn how different resistance training programs affects blood sugar in young athletes with T1DM.
- Trial name
- NCT05315037
- Testing
- Resistance Training
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of Louisville
Type 2 Diabetes Mellitus, Chronic Kidney Disease
A Study to Learn More About Chronic Kidney Disease (CKD) in Patients With Type 2 Diabetes Mellitus (T2DM)
In this observational study, data from the recent past of patients with type 2 diabetes mellitus and chronic kidney disease will be studied.
- Trial name
- CKD-T2DM (NCT05004428)
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 336,376 people
- Sponsor
- Bayer
Diabetes Mellitus, Type 1
Prolonged Remission Induced by Phenofibrate in Children Newly Diagnosed With Type 1 Diabetes.
The goal of this clinical trial is to evaluate of the effect of phenofibrate on the functions of beta cells in children with new diagnosis of type 1 diabetes.
- Trial name
- PRIFEN (NCT05909800)
- Testing
- Phenofibrate
- Where
- 2 sites in Poland
- Volunteers
- 102 people
- Sponsor
- Medical University of Warsaw
Diabetes Mellitus, Type 1
Integrated Behavioral Healthcare for Youth With Type 1 Diabetes
The purpose of this study is to understand how behavioral health care that is coordinated with diabetes medical care compared with behavioral care that is provided in the community (and therefore not coordinated with diabetes…
- Trial name
- NCT05915975
- Testing
- Behavioral Care Coordinated with Medical Care Intervention, Behavioral Care Not Coordinated with Medical Care Intervention
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Type 1 Diabetes
Evaluation of The Postprandial Impact of Automated Priming Bolus for Full Closed Loop Insulin Delivery
The purpose of this study is to understand the impact of the automated priming boluses on the safety and feasibility of a new fully automated AP controller.
- Trial name
- Rocket-BPS (NCT05528770)
- Testing
- FCL+BPS, FCL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Marc Breton
Fasting
Comparison of Two Protocols on the Implementation of a Fasting Day in Type 1 Diabetes
This is a prospective study with a "crossover design", where fasting with a day of complete fasting and a fasting day with the permission intake of calories- and carbohydrate-free foods are compared in a randomized order.
- Trial name
- NCT02667769
- Testing
- Fasting day
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Diabeteszentrum Bad Lauterberg im Harz
Diabetes Mellitus, Type 1
PINIT Study: Primary Intranasal Insulin Trial
Type 1 diabetes (T1D) results from an autoimmune destruction of the insulin-producing beta cells. Administration of mucosal insulin in islet autoantibody-negative children who are genetically predisposed for T1D offers the…
- Trial name
- NCT03182322
- Testing
- intranasal insulin
- Where
- 2 sites in Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Diabetes Mellitus, Type 1
Comprehensive Care in Type 1 Diabetes and Associated Outcomes
Quasi-experimental, retrospective, before and after study, with a control group, to evaluate the effect of an intervention based on disease management, on metabolic control and hospitalizations, in a group of patients with type…
- Trial name
- AIDDA (NCT03835195)
- Testing
- Diabetes Disease Management Program, Usual Care Process
- Where
- Colombia
- Volunteers
- 50 people
- Sponsor
- Universidad de Antioquia
Type 1 Diabetes
Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)
In this 2-year randomized clinical trial, we will implement and assess the impact of a behavioral/psychoeducational intervention to reduce diabetes distress and improve glycemic outcomes in adolescents and young adults, aged…
- Trial name
- NCT05413239
- Testing
- Psychoeducation to reduce diabetes distress and improve glycemic outcomes
- Where
- 2 sites in United States
- Volunteers
- 217 people
- Sponsor
- Joslin Diabetes Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.