Clinical trials: Diabetes Mellitus Poor Control
Type 1 Diabetes
Clinical Utility of Tight Objectives of Advanced Hybrid Closed-loop Systems Among Type 1 Diabetes Patients (TightT1AHCL)
Diabetes is a chronic disease with a relevant public health burden. Maintaining blood glucose levels as close to normal as possible is essential to avoid the associated microvascular and macrovascular complications.
- Trial name
- TightT1AHCL (NCT06466967)
- Testing
- Advanced hybrid closed-loop CamAPS FX
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Castilla-La Mancha Health Service
Type 2 Diabetes
Self-care Management Programme for Type 2 Adult DM Patients With Poor Glycemic Control
Type 2 diabetes becomes the most prevalence chronic disease worldwide. Most type 2 diabetes patient are under the care in public general out-patient clinic in Hong Kong.
- Trial name
- T2DM (NCT04092023)
- Testing
- nursing education
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Diabetes, Poor Glycemic Control
Insulin Pump Therapy and Continuous Glucose Monitoring in Diabetic Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients
The aims of this study are to assess the potential efficacy and safety of insulin pump to improve glycemic control in conjunction with continuous glucose monitoring (CGMS) for diabetic continuous ambulatory peritoneal dialysis…
- Trial name
- NCT01324557
- Testing
- CSII and MDI
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Guangdong Provincial People's Hospital
Diabetes Mellitus, Type 2
Professional Continuous Glucose Monitoring as an Adjuvant Educational Tool for Improving Glycemic Control in Patients With Type 2 Diabetes.
The investigators conducted a three-month quasi-experimental study with an intervention and control group and ex-ante and ex-post evaluations in one family medicine clinic in Mexico City.
- Trial name
- NCT04667728
- Testing
- Professional continuous glucose monitoring (CGM) sensor (iPro™2)
- Where
- Mexico
- Volunteers
- 302 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Diabetes Mellitus, Type 2
IMPACT Intervention
Introduction : The prevalence of type 2 diabetes is increasing in France, especially in deprived districts. The Itineraires Medico-sociaux Programme d'Accompagnement sur un Territoire (IMPACT) intervention is intended for…
- Trial name
- NCT04616053
- Testing
- IMPACT intervention
- Volunteers
- 140 people
- Sponsor
- Pole de Sante Chambery Nord
Patient Readmission, Pulmonary Disease, Chronic Obstructive
UM CRMC RecuR Score Pilot
This study will look to implement a plan for enhanced transitional care for patients at high risk of unplanned hospital readmission in hopes of reducing their risk for readmission in the first 30 days post discharge from an…
- Conditions
- Patient Readmission, Pulmonary Disease, Chronic Obstructive, Heart Failure, Diabetes Mellitus Poor Control
- Trial name
- NCT05765903
- Testing
- Standard of Care, Enhanced Care
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Diabetes Mellitus
The Guardcontrol Trial: Study to Assess if Type 1 Diabetics Can Improve Using the Real-time Values of Guardian RT
The objective of the study is to determine whether patients with poor glycemic control can improve metabolic control using the real-time values of the Guardian® RT compared to conventional self-monitoring blood glucose…
- Trial name
- NCT00111228
- Testing
- Guardian RT, SMBG only
- Where
- 8 sites in France, Germany and 5 more
- Volunteers
- 162 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 1 Diabetes
Testing MST to Improve Adherence Among Youth With Chronic Poor Metabolic Control
The protocol is a randomized clinical trial providing Multisystemic Therapy (MST), an intensive home-based family psychotherapy intervention, to a group of urban adolescents with poorly controlled Type 1 diabetes and their…
- Trial name
- NCT00519935
- Testing
- Multisystemic Therapy
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Wayne State University
Type 2 Diabetes
A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Trial to Evaluate the Clinical Efficacy and Safety of Yogliptin Tablets
The purpose of this study is to assess the efficacy of Yogliptin (as monotherapy) compared with placebo after 24 weeks, and the safety (up to 52 weeks) of Yogliptin in Chinese patients with Type 2 diabetes who are insufficient…
- Trial name
- NCT05318326
- Testing
- Yogliptin 400mg group, Yogliptin 200mg group
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Chengdu Easton Biopharmaceuticals Co,Ltd
Type 2 Diabetes
Clinical Study of Retagliptin Phosphate Combined With Metformin in the Treatment of Type 2 Diabetes
Retagliptin phosphate tablet is a DPP IV inhibitor durg，study number is HR-SP2086-304. The primary purpose of the study is to evaluate the efficacy of the combination of Retagliptin phosphate and metformin compared with placebo…
- Trial name
- NCT05054842
- Testing
- Retagliptin phosphate tablets、metformin sustained-release tablets
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Prediabetes, Autonomic Nervous System Imbalance
Enhancing the Vagal Tone in Prediabetes Individuals
This is a 2-year course of study. A randomized control trial will be conducted, in which 90 prediabetes individuals will be recruited and randomly assigned them into the wait-list control group or experimental group to test the…
- Conditions
- Prediabetes, Autonomic Nervous System Imbalance, Poor Glycemic Control, Psychological Distress
- Trial name
- NCT03616275
- Testing
- HRV biofeedback
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Defense Medical Center, Taiwan
Diabetes Mellitus, Non Insulin Dependent Diabetes Mellitus
ED Diabetes Screening and Outpatient Care - Aim 3
This goal of this NIH funded R01 study is to identify risk factors for not being able to follow-up for a new diagnosis of diabetes in the emergency department and improve linkage of these newly diagnosed patients to appropriate…
- Trial name
- NCT05899023
- Testing
- Telehealth Bridge Visits, Standard of Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Randomized Controlled Trial, Diabetes Mellitus
Effect of Apple Cider Vinegar in Type 2 Diabetics
Background: apple cider vinegar is natural traditional health beneficial nutraceutical used for many aliments. Diabetes mellitus (DM) has been considered a globally major health problem and posing health burden on families and…
- Trial name
- NCT03593135
- Testing
- Apple Cider Vinegar and tablet Tagipmet (Metformin + Sitagliptin group), Water with Apple Cider vinegar flavor and tablet Tagipmet (Metformin + Sitagliptin group)
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Type 2 Diabetes Mellitus
Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy
This is a Multi-center, Randomized, Double-Blinded, Parallel and Placebo-Controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients with Poor Glycemic Control via…
- Trial name
- NCT05326490
- Testing
- PB-201, Metformin hydrochloride
- Where
- China
- Volunteers
- 546 people
- Sponsor
- PegBio Co., Ltd.
Type 2 Diabetes
Multiple-dose Tolerability and Pharmacokinetic of IBI362 in Chinese Patients With T2DM
This trial is aimed to investigate the safety, tolerability, PK and PD of multiple subcutaneous injections of IBI362 in Chinese patients with type 2 diabetes who have poor glycemic control after lifestyle or metformin intervention
- Trial name
- NCT04466904
- Testing
- IBI362, Dulaglutide
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Type 1 Diabetes, Puberty: >Tanner 2 Breast Development or Testis >4ml
Rosiglitazone and Insulin in T1DM Adolescents
Type 1 Diabetes is the most common life-long disorder with onset in childhood. Patients need insulin injections, blood sugar monitoring several times each day, and adhere to a strict diet.
- Trial name
- NCT00372086
- Testing
- Rosiglitazone
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- The University of New South Wales
Diabetes Mellitus, Type 2
Telephone Therapeutic Education Program in DM2 Patients With Poor Metabolic Control
Diabetes Mellitus (DM) is one of the most prevalent chronic diseases worldwide and with a significant impact on health spending.
- Trial name
- TTEDMV1 (NCT04932356)
- Testing
- Therapeutic education by phone, Therapeutical education traditional
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- Mª Dolores Rodríguez Garrido
Type 2 Diabetes Mellitus - Poor Control
A Study of CJC-1134-PC Injection in Antidiabetic Treatment-naive Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control
This study is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of CJC-1134-PC Injection Administered Once Weekly in Antidiabetic Treatment-naive Patients…
- Trial name
- NCT07058545
- Testing
- CJC-1134-PC Injection
- Where
- China
- Volunteers
- 474 people
- Sponsor
- Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd.
Type 2 Diabetes, Glycemic Control
Diabetes Management in Low-Income Hispanic Patients
The overall goal of this randomized clinical trial (RCT) is to test the efficacy of a culturally- and literacy-tailored cognitive-behavioral intervention designed to enhance adherence to diabetes self-management behaviors and…
- Trial name
- NCT00848315
- Testing
- Cognitive Behavioral Intervention
- Where
- 5 sites in United States
- Volunteers
- 252 people
- Sponsor
- University of Massachusetts, Worcester
Diabetes Mellitus, Type 1, Depressive Symptoms
Towards a Better Understanding of Diabetes Distress, Depression and Poor Glycaemic Control (DIA-LINK Study)
The DIA-LINK Study is a prospective observational study analysing longitudinal associations and mediating links between diabetes distress (DD), depressive symptoms (DS) and glycaemic outcomes in people with type 1 diabetes…
- Conditions
- Diabetes Mellitus, Type 1, Depressive Symptoms, Stress, Psychological, Glucose, High Blood
- Trial name
- DIA-LINK (NCT03811132)
- Testing
- Observation
- Where
- 2 sites in Germany
- Volunteers
- 208 people
- Sponsor
- Norbert Hermanns