Clinical trials: Diabetes Mellitus Poor Control
Type 2 Diabetes
The Experiment of Noiiglutide Injection in Type 2 Diabetes Patients
This study aims to confirm that SHR20004 is more effective than placebo in controlling blood glucose in patients with type 2 diabetes. Evaluate the efficacy, safety, and pharmacokinetics of SHR20004 after 24 weeks of treatment.
- Trial name
- NCT06649773
- Testing
- Noiiglutide Injection
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Type 2 Diabetes Mellitus (T2DM)
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus
The main purpose of this study is to investigate the Efficacy and Safety of GZR18 Injection in Chinese Subjects with Type 2 Diabetes Mellitus and Poor Blood Glucose Control by Metformin Monotherapy or in Combination with…
- Trial name
- Optimum 2 (NCT06778967)
- Testing
- GZR18, semaglutide
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Gan & Lee Pharmaceuticals.
Diabetes Mellitus, Type 2
Impact of a Program of Non-pharmacological Intervention in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to determine whether a non-drug intensive program can help improve control of type 2 diabetes mellitus.
- Trial name
- NCT02456064
- Testing
- Lifestyle counseling
- Volunteers
- 25 people
- Sponsor
- Equipo Multidisciplinar Sanitario CS Foietes
Type 2 Diabetes, Poor Glycemic Control
Telemedicine as a Means to Achieving Good Diabetes Control Among Patients With Type 2 Diabetes
The aim of the study is to investigate the effect of telemedicine among the group of type-2-diabetics who, despite rehabilitation, remain poorly regulated.
- Conditions
- Type 2 Diabetes, Poor Glycemic Control, Medication Adherence
- Trial name
- NCT01688778
- Testing
- Telemedicine
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Bispebjerg Hospital
Diabetes
The Cost-efficacy of Psychological Intervention for Strengthening Parental Authority Among Parents of Diabetic Adolescents With Poor Glycemic Control
A three arms, open, randomized interventional study including 100 participants in order to evaluate the cost-efficacy of psychological intervention for strengthening parental authority among parents of diabetic adolescents with…
- Trial name
- NCT00622856
- Testing
- psychological intervention, Diabetes education
- Where
- Israel
- Volunteers
- 55 people
- Sponsor
- Rabin Medical Center
T2DM (Type 2 Diabetes Mellitus)
Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes
The goal of this clinical study is to evaluate the efficacy and safety of Berberine Ursodeoxycholate (HTD1801) compared to placebo in patients with type 2 diabetes, inadequately controlled with diet and exercise alone.
- Trial name
- SYMPHONY-1 (NCT06350890)
- Testing
- HTD1801
- Where
- 56 sites in China
- Volunteers
- 408 people
- Sponsor
- Shenzhen HighTide Biopharmaceutical Ltd.
Type 2 Diabetes Mellitus
Efficacy and Safety of Voglibose Compared With Acarbose in Participants With Type 2 Diabetes
The primary purpose of this study is to evaluate the efficacy of voglibose versus acarbose combined with metformin in participants with type 2 diabetes mellitus (T2DM) by evaluating levels of glycosylated hemoglobin.
- Trial name
- NCT02049814
- Testing
- Metformin, Voglibose, Acarbose
- Where
- 18 sites in China
- Volunteers
- 494 people
- Sponsor
- Takeda
Type 2 Diabetes Mellitus (T2DM)
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Subjects With Type 2 Diabetes Mellitus and Poor Blood Glucose Control by Diet and Exercise
The main purpose of this study is to investigate the Efficacy and Safety of GZR18 Injection in Chinese Subjects with Type 2 Diabetes Mellitus and Poor Blood Glucose Control by Diet and Exercise
- Trial name
- Optimum 1 (NCT06777238)
- Testing
- GZR18
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Gan & Lee Pharmaceuticals.
Type 2 Diabetes, Poor Glycemic Control
Effect of Intensive Monitoring of Patients With Poorly Controlled Type 2 Diabetes With Different Glycemic Background
In Turkey, only 55% of patients with type 2 diabetes have been diagnosed, and 91% of these patients have been receiving treatment. The rate of patients reaching the treatment target is 50%.
- Trial name
- NCT06385899
- Where
- Turkey (Türkiye)
- Volunteers
- 266 people
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Glucose Metabolism Disorders (Including Diabetes Mellitus), Diabetes Mellitus, Type 1
Flash Glucose Measure System and Continuous Subcutaneous Insulin Infusion Therapy in Poorly Controlled Diabetes Type 1 Patients
Patients with diabetes type 1 with poor glycemic control will be switched to insulin pump and FGM system (Flash Glucose Monitoring) during 6 months, correlated to the hypothesis that they could benefit from this intervention by…
- Trial name
- FREESTYLE (NCT03671161)
- Testing
- Insulin Pump and flash glucose monitoring
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Diabetes Mellitus, Type 2, Diabetes
Evaluation of Fuling Yunhua Granules and Dihuang Baoyuan Granules in Drug Naive Type 2 Diabetes Patients
The goal of this investigator-initiated clinical trial is to investigate the efficacy and safety of sequential therapy of Fuling Yunhua Granules (prescription A) and Dihuang Baoyuan Granule (prescription B) in the treatment of…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes, Type2diabetes
- Trial name
- NCT06575478
- Testing
- Fuling Yunhua Granules, Dihuang Baoyuan Granules
- Where
- China
- Volunteers
- 95 people
- Sponsor
- Beijing Supreme Life Pharmaceutical Technology Co., Ltd.
Diabetes, Poor Glycemic Control
Insulin Pump Therapy and Continuous Glucose Monitoring in Diabetic Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients
The aims of this study are to assess the potential efficacy and safety of insulin pump to improve glycemic control in conjunction with continuous glucose monitoring (CGMS) for diabetic continuous ambulatory peritoneal dialysis…
- Trial name
- NCT01324557
- Testing
- CSII and MDI
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Guangdong Provincial People's Hospital
Type 2 Diabetes Mellitus - Poor Control
Continuous Glucose Monitoring, Diabetes Education, and Peer Support for Management of Uncontrolled Type 2 Diabetes
This research study is investigating whether a diabetes virtual group visit program using a continuous glucose monitor (CGM) can help improve glucose levels and quality of life in individuals with uncontrolled type 2 diabetes.
- Trial name
- COMPASS (NCT07054125)
- Testing
- Education, lifestyle counseling, and peer support
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Whole Endo
Type2 Diabetes Mellitus
A Nurse-led Smartphone-based Self-management Programme for Type 2 Diabetes Patients With Poor Blood Glucose Control
Aim. To develop and compare a nurse-led smartphone-based self-management programme with an existing nurse-led diabetes service on health-related outcomes of type 2 diabetes patients with poor glycaemic control in Singapore.
- Trial name
- NCT03088475
- Testing
- nurse-led smartphone-based self-management programme, exiting nurse-led diabetes service
- Volunteers
- 128 people
- Sponsor
- National University of Singapore
Type 2 Diabetes Mellitus
Glycemic Control and Endothelial Function in Patients With Type 2 Diabetes
Study objective To evaluate the mechanism behind endothelial dysfunction in patients with type 2 diabetes in relation to the level of glycaemic control. Primary endpoint: Change in endothelium dependent vasodilatation (EDV).
- Trial name
- AIDdiabetes (NCT03480945)
- Testing
- serotonin
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
T2DM (Type 2 Diabetes Mellitus)
Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control
The main objective of this study is to compare the efficacy and safety of the triple combination therapy of Met/SGLT-2i/GLP-1RA or other oral antidiabetic drugs in patients with type 2 diabetes exhibiting poor glycemic control.
- Trial name
- MESSAGE (NCT07244003)
- Testing
- Metformin, Triple Therapy of Other Oral Antidiabetic Drugs, ganagliflozin
- Where
- China
- Volunteers
- 430 people
- Sponsor
- Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Diabetes (DM)
Evaluation of the Impact of a Food is Medicine Program on Diabetes-related Health Outcomes for People With Type 2 Diabetes in a Low Income Community-based Setting Compared to Usual Care
The goal of this clinical trial is to learn if a food is medicine intervention (Healthy Food Rx) improves diabetes-related outcomes in adults diagnosed with type 2 diabetes in a low-income, community-based setting more than usual…
- Trial name
- NCT07529184
- Testing
- Food is medicine
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- Public Health Institute Center for Wellness and Nutrition
Type 2 Diabetes Mellitus
Evaluate Safety and Effectiveness of MBX-102 in Type 2 Diabetes Patients With Poor Glycemic Control on Metformin
To define the relative efficacy, safety and tolerability profiles of oral daily MBX-102 at daily doses of 400 and 600 mg vs. placebo and Actos® 30 mg (up-titrated to 45 mg after 8 weeks) when administered for up to 24 weeks in…
- Trial name
- NCT00814372
- Testing
- MBX-102, Actos, Metformin
- Where
- 26 sites in United States, India
- Volunteers
- 242 people
- Sponsor
- Gilead Sciences
Cardiovascular Diseases, Cardiovascular Risk Factor
Cardiovascular Health Awareness Program (CHAP) in Subsidized Social Housing
This project aims to improve the cardiovascular health of seniors living in subsidized housing by implementing the successful community-based Cardiovascular Health Awareness Program (CHAP).
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Diabetes Mellitus
- Trial name
- NCT03549845
- Testing
- Cardiovascular Health Awareness Program
- Where
- Canada
- Volunteers
- 2,742 people, healthy volunteers welcome
- Sponsor
- McMaster University
Type 2 Diabetes
A Study of IBI362 in Poorly Controlled Type 2 Diabetes Patients Only Through Diet and Exercise
This is a multicenter, randomized, double-blind, placebo-controlled phase III clinical study to evaluate the effectiveness and safety of IBI362 in patients with type 2 diabetes (T2D) with poor glycemia control only through diet…
- Trial name
- NCT05628311
- Testing
- IBI362
- Where
- China
- Volunteers
- 319 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.