Clinical trials: Diabetes Mellitus Risk
Diabetes Mellitus
Sex Differences in the Risk of Cardiovascular Diseases Associated With Diabetes
To evaluate the risk of cardiovascular events associated with medication use for controlling blood glucose, blood pressure and cholesterol levels in men and women with diabetes treated in primary care
- Trial name
- NCT02542774
- Testing
- No intervention is given.
- Where
- United Kingdom
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Hypertension, Diabetes Mellitus
Diabetes Risk Evaluation and Management Tele-monitoring Study (DREAM-Tel)
The purpose behind the proposed research is that diabetes care in First Nations people can be improved by involvement of a Home Care team providing diabetes education and management, supported by emerging technology, specifically…
- Trial name
- DREAM-Tel (NCT00325624)
- Testing
- Bluetooth-enabled Glucometer
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Sunnybrook Health Sciences Centre
Type 2 Diabetes Mellitus (T2DM), Hypertension
Eating Window and Sleep Disorders on Glycemic Control, Cardiovascular Risk, and Weight Loss
This project aims to offer a quantitative and qualitative nutritional approach, along with educational nutritional guidelines for participants with Non-Communicable Chronic Diseases.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Hypertension, Obesity and Type 2 Diabetes, Cardiovascular Diseases
- Trial name
- NCT06735859
- Testing
- Comparison of eating windows intervention
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Pre-diabetes
A Community-based Weight Loss Programme for Chinese Overweight Adults With Pre-diabetes
Type 2 diabetes (T2DM) is a serious chronic condition and one of the world's fastest growing health problems. The onset of T2DM is gradual, with most individuals progressing through a state of pre-diabetes.
- Trial name
- NCT03609697
- Testing
- group-based lifestyle intervention, Minimal intervention (SMS intervention)
- Where
- Hong Kong
- Volunteers
- 180 people
- Sponsor
- The University of Hong Kong
Overweight, PreDiabetes
Hydroxytyrosol Dietary Supplement and Prevention of Age-Related Diseases
The primary objective of this study is to ascertain the effects of chronic consumption of a hydroxytyrosol-rich extract from olive in a population at high risk of developing age-related pathologies such as type 2 diabetes and…
- Trial name
- HT15 (NCT06295913)
- Testing
- Group 1, hydroxytyrosol-rich extract capsule
- Where
- Spain
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Diabetes, Pre-diabetes
Glucose Risk Assessment in Employer Populations
This is an observational study to understand the glucose characteristics of the general population (normal glucose, pre-diabetes, and diabetes).
- Conditions
- Diabetes, Pre-diabetes, Glucose Intolerance
- Trial name
- NCT04529824
- Testing
- Dexcom G6 Continuous Glucose Monitor (CGM) System
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- DexCom, Inc.
Type 1 Diabetes
Evaluation of an Early Screener to Identify Long-term Problems With Regard to Metabolic Control and Treatment Adherence Among Children and Adolescents With Type 1 Diabetes
Background: Type 1 diabetes is one of the most common chronic illnesses among children and adolescents. Although, intensive medical care is provided for these patients, some of them have poor metabolic control.
- Trial name
- NCT03642483
- Where
- Switzerland
- Volunteers
- 61 people
- Sponsor
- University Children's Hospital, Zurich
Diabetes Mellitus, Type 2
Better Risk Perception Via Patient Similarity to Control Hyperglycemia and Sustained by Telemonitoring
Background: Diabetes significantly raises the likelihood of complications, thereby increasing the risk of diabetes-related mortality, particularly due to vascular complications.
- Trial name
- BRILLIANT (NCT06607497)
- Testing
- Intervention using an AI enabled risk communication tool (PERDICT.AI), Telemonitoring with Primary Tech Enhanced Care (PTEC-DM)
- Where
- Singapore
- Volunteers
- 360 people
- Sponsor
- SingHealth Polyclinics
Overweight, Obesity
Correlation of Irisin and Adipokine Levels With Body Mass Index and Risk Factors for Metabolic Syndrome in Hispanic Children
Childhood obesity is one of the most serious global public health challenges of the 21st century (Daniels et al., 2009). Mexico has the highest prevalence of obesity, (Secretaría de Salud, 2009); 34.4% of children and 35% of…
- Conditions
- Overweight, Obesity, Thinness
- Trial name
- NCT02320110
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey
Cardiovascular Diseases, Hypercholesterolemia
Plant Sterols on Cardiovascular Markers, Microbiota and Sterol Metabolism (Cardiofoodsterol)
Potential cholesterol-lowering effect of a regular intake of a plant sterol (PS)-containing food supplement, in overweight/obese type 1 or 2, normoglycemic/pre-diabetic, with LDL-cholesterol values > 115 mg/dl and not…
- Conditions
- Cardiovascular Diseases, Hypercholesterolemia, Prediabetic State, Overweight and Obesity
- Trial name
- NCT06481020
- Testing
- Plant sterols 2g/day
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- University of Valencia
Pre Diabetes
Effects of Fos Biomedical Device on Diabetes Risk Factors and Sleep Quality in Adults at Risk for Type 2 Diabetes
Purpose Phototherapy has an array of potential benefits in human health. The effects of a non-transdermal Fos Biomedical product (which utilizes the concept of phototherapy) on diabetes risk factors and sleep quality in people at…
- Trial name
- NCT05628597
- Testing
- Fos Biomedical patch product
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Griffin Hospital
Prediabetes, Cardiovascular Risk Factors
A Survey to Evaluate the Cardiovascular Risk Status of Subjects With Pre-Diabetes in Hong Kong
Hypothesis: A high cardiovascular risk is present in subjects with pre-diabetes in Hong Kong Chinese. The investigators plan to assess Chinese subjects in Hong Kong who have pre-diabetes (impaired fasting glucose, IFG; or…
- Trial name
- JADE-HK2 (NCT00786890)
- Testing
- observational, no intervention needed
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Chinese University of Hong Kong
Cardiovascular Disease, Diabetes
Soybean Oil Trial of cArdiovascular Risk
The study will determine the effects of different types of soybean oils on biomarkers of risk for cardiovascular disease and diabetes.
- Conditions
- Cardiovascular Disease, Diabetes, Metabolic Syndrome
- Trial name
- STAR (NCT02404207)
- Testing
- Soybean oil, High-oleic soybean oil, High-oleic soybean oil + fully hydrogenated soybean oil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- USDA Beltsville Human Nutrition Research Center
Pancreatic Cancer
Secretin (ChiRhoStim) Pancreas Perfusion for Pancreatic Adenocarcinoma
The purpose of this study is to test if secretin-enhanced CT is a useful noninvasive screening tool for pancreatic cancer in a high-risk population.
- Trial name
- NCT00587132
- Testing
- Synthetic Human Secretin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mayo Clinic
Pre-diabetes
Prohealth@Home: A Feasibility Study Investigating the Use of a Lifestyle App in People at Risk of Type 2 Diabetes
More than a third of the adult population in England have prediabetes, a condition that occurs when glucose levels are higher than normal but not high enough to be diagnosed as diabetes.
- Trial name
- NCT02450500
- Testing
- Lifestyle counselling
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Plymouth
Diabetes
Evaluation of Group Lifestyle Balance Maintenance Strategies
Heart disease is a leading cause of death in people in the United States. It is a major problem for those with diabetes. Conditions called the metabolic syndrome and pre-diabetes increase risk for diabetes and heart disease.
- Trial name
- NCT00869609
- Testing
- GLB Traditional Maintenance (TM), GLB-Carb-focused Maintenance (CF)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
CKD, Type 2 Diabetes
Fib to Alb Ratio in Type 2 Dkd
Aimed to investigate the association of fibrinogen to albumin ratio (FAR) with DKD type 2 and to prove its possible role as a novel biomarker to predict and prevent DKD progression.
- Trial name
- NCT05691985
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Type 2 Diabetes, Pre-diabetes
Testing the Effectiveness of Different Messaging Approaches to Increase Doctor Visits Amongst Individuals With Risk Factors for Diabetes
The purpose of the research is to test the effectiveness of different messaging approaches to nudge members of Vitality and Discovery Health, with risk factors for diabetes (based on data from the Vitality Health Check and…
- Trial name
- NCT05755555
- Testing
- Visit a doctor
- Where
- South Africa
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Wits Health Consortium (Pty) Ltd
Sleep, Sleep Deprivation
Sleep Loss and Energy Metabolism in People With Family History of Type 2 Diabetes.
The use of energy from food changes when people sleep. However, it is still not known if differences in the amount of nighttime sleep have an effect on the amount of energy that people who have a relative with type 2 diabetes…
- Conditions
- Sleep, Sleep Deprivation, Insulin Resistance, Type 2 Diabetes
- Trial name
- NCT00724087
- Testing
- 5.5-hour bedtime, 8.5-hour bedtime
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Diabetes Mellitus, Type 1
Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics
The goal of this clinical trial is to determine if transitioning to automated insulin delivery (AID) systems, can improve objectively measured sleep quality and quantity and alleviate cardiovascular risk factors in both children…
- Trial name
- AID-BEYOND (NCT06469593)
- Testing
- Automated insuling delivery system
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Steno Diabetes Center Copenhagen
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