Clinical trials: Diabetes Mellitus Risk
Pediatric Obesity, Type 2 Diabetes
A Family Based Intervention to Reduce the Risk of Type 2 Diabetes in Children
The purpose of this study was to determine if a family-focused lifestyle intervention helps to improve the health status, behaviors, and adjustment of overweight children.
- Conditions
- Pediatric Obesity, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- FBI (NCT01146314)
- Testing
- Family Focused Lifestyle Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Nemours Children's Clinic
Type 2 Diabetes Mellitus (T2DM)
2025 Hypoglycemia Early-Warning and Physician-Nurse Collaborative Management Trial in Type 2 Diabetes
The goal of this clinical study is to learn whether a physician-nurse collaborative intervention guided by an Intelligent Hypoglycemia Risk Early-Warning System can reduce hypoglycemia and improve glycemic control in hospitalized…
- Trial name
- NCT07314749
- Testing
- Physician-Nurse Collaborative Intervention Guided by Intelligent Hypoglycemia Risk Early-Warning System, Usual Care
- Where
- China
- Volunteers
- 1,255 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Diabetes
Walnut Ingestion in Adults at Risk for Diabetes: Effects on Body Composition, Diet Quality, and Cardiac Risk Measures
Proposed is a randomized, controlled, modified Latin square parallel design study with two treatment arms to examine walnut consumption effects on diet quality, body composition, and markers of cardiovascular risk in adults at…
- Trial name
- Walnut3 (NCT02330848)
- Testing
- Walnut Ad libitum diet, Walnut Calorie controlled
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Griffin Hospital
Cardiac Diseases, Stroke
DanceFit Prime: A Dance Based Physical Activity and Nutritional Intervention for Primary Care - A Feasibility Study
Regular physical activity improves physical and mental health and reduces the risk of heart disease, stroke, cancer, diabetes, obesity and premature death from any cause.
- Conditions
- Cardiac Diseases, Stroke, Diabetes Mellitus, Dementia
- Trial name
- DanceFit (NCT02159014)
- Testing
- Facilitated group-based aerobic dance, Online, video prompted, individual aerobic dance, Facilitated group-based nutritional intervention
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- North Essex Partnership NHS Foundation Trust
Prediabetes
Preventing Diabetes in Those at Risk by Having a Facilitator and Family Doctor Encourage Healthy Activity and Eating Habits
Nearly six million Canadians are living with an increased risk of diabetes (prediabetes) and approximately 50% of these will develop type 2 diabetes within five years.
- Trial name
- FLIP (NCT01589835)
- Testing
- Lifestyle changes
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- University of British Columbia
Type2 Diabetes
Risk Assessment of Type 2 Diabetes in Pharmacies
Background: Due to lack of clear symptoms, type 2 diabetes can remain undetected for many years. Our aim was to explore the capacity of Norwegian community pharmacies to identify people at high risk of developing type 2 diabetes…
- Trial name
- NCT03979768
- Testing
- Diabetes risk assessment service in Norwegian community pharmacies
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Diabetes, Weight Gain
The GlasVEGAS Study (Glasgow Visceral & Ectopic Fat With Weight Gain in South AsianS)
South Asians have a much higher risk of diabetes compared to Europeans and investigators don't know why this is. Investigators think that South Asians' capacity to store fat safely under the skin is lower than Europeans, so they…
- Conditions
- Diabetes, Weight Gain, Weight Loss, Cardiovascular Disease
- Trial name
- GlasVEGAS (NCT02399423)
- Testing
- Weight gain, Weight loss
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Gestational Diabetes
Efficacy of Myo-inositol in Preventing Gestational Diabetes in High-risk Pregnant Women
The aim of this study is to evaluate the efficacy of myo-inositol in preventing gestational diabetes in high risk pregnant women.
- Trial name
- NCT01511835
- Testing
- inositol + folic acid, Folic Acid
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Gestational Diabetes
The Value of Second-trimester Uterine Artery Doppler Analysis in the Prediction of GDM in a Low- Risk Population
In the current literature, there are not enough studies related to the use of uterine artery Doppler indices in the second trimester for the prediction of GDM.
- Trial name
- PS-GDM-2022 (NCT05488197)
- Testing
- uterine artery doppler at 18-23 weeks of pregnancy
- Where
- Turkey (Türkiye)
- Volunteers
- 700 people
- Sponsor
- Haseki Training and Research Hospital
Cardiovascular Diseases, Heart Diseases
VLDL and LDL Particle Types as Coronary Heart Disease Risk Factors
To evaluate very low density lipoprotein (VLDL) and low density lipoprotein (LDL) particle types as predictors of initial coronary events.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00065793
- Volunteers
- 1,478 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Prediabetes
Piloting FUERTE: Federally qUalified Health Centers Engaging Hispanic Men at Risk of diabeTEs
The goal of this study is to learn whether FUERTE (Federally qUalified Health Centers Engaging Hispanic Men at Risk of diabeTEs) can facilitate referrals of Hispanic men with prediabetes to the Diabetes Prevention Program (DPP)…
- Trial name
- FUERTE (NCT07878806)
- Testing
- FUERTE Arm, Standard care, No Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Diabetes
Preventing ESRD in Overt Nephropathy of Type 2 Diabetes
Nephropathy of type 2 diabetes is the leading cause of end stage renal disease (ESRD) world-wide and is associated with a dramatic excess cardiovascular morbidity and mortality.
- Trial name
- VALID (NCT00494715)
- Testing
- Benazepril, Valsartan, Benazepril/Valsartan
- Where
- 15 sites in Italy, Slovenia
- Volunteers
- 102 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Obesity, Diabetes
Effect of a Treatment of Lifestyle Changes on the Prevalence of Metabolic Syndrome and Body Weight in Mexican Women
The metabolic syndrome is a group of cardiometabolic risk factors that reflect a sedentary lifestyle and the excessive intake of food among the risk factors that comprise it are located the obesity, hyperglycemia, dyslipidemia…
- Conditions
- Obesity, Diabetes, High Blood Pressure, Dyslipidemia
- Trial name
- MPATPCDNC (NCT02247635)
- Testing
- Healthy lifestyle and adherence
- Where
- Mexico
- Volunteers
- 180 people
- Sponsor
- Mexican National Institute of Public Health
Type1 Diabetes Mellitus
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study)
Type 1 diabetes (T1D) results from destruction of insulin-producing beta cells in the pancreas by the body's own immune system (autoimmunity).
- Trial name
- EXE-T1D (NCT03369821)
- Testing
- Beta Cell Loss and Immune Function, Immune Function with RNAseq
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 300 people
- Sponsor
- University of Exeter
Obesity, Type 2 Diabetes
Reducing Obesity and Type 2 Diabetes in High Risk Youth
Compare the effect of the HEALT[e]TEEN program and a HEALTH[e]TEEN plus coping skills training delivered to high school students on BMI, nutrition and physical activity behaviors, and self-efficacy over 6 months.
- Trial name
- HEALTH[e]TEEN (NCT01560676)
- Testing
- HEALTH[e]TEEN, HEALTH[e]TEEN + CST
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Yale University
Type 2 Diabetes
Effect of Vildagliptin Versus Dapagliflozin as Add on Therapy to Metformin on Cardiovascular Risk Factors
The overarching hypothesis of this study is that vildagliptin (vilda) as add on therapy to metformin (met) in Egyptian type 2 diabetic obese patient will produce an equal, if not better, glycemic control and will reduce…
- Trial name
- NCT07077525
- Testing
- Dapagliflozin + Metformin, Vildagliptin + Metformin
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Al-Azhar University
Atherosclerosis, Cardiovascular Diseases
Intensive Glycemic Control and Skeletal Health Study
The purpose of the ACCORD-BONE Study is to investigate the effects of intensive glycemic control for type 2 diabetes (in ACCORD participants) on factors related to bone health, including, fractures, falls, and bone mineral…
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia, Hypertension
- Trial name
- ACCORD-BONE (NCT00324350)
- Testing
- hypoglycemic agents, hydroxymethylglutaryl-CoA Reductase inhibitors, hypertensive agents
- Where
- 5 sites in United States, Canada
- Volunteers
- 7,287 people
- Sponsor
- University of California, San Francisco
Atherosclerosis
Longitudinal Study in Perimenopausal Women With Risk Factors for Atherosclerosis
The study hypothesis (or theory) is that monthly loss of iron before menopause may reduce women's risk of hardening of the arteries, or atherosclerosis.
- Trial name
- NCT00921011
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Ohio State University
Obesity, Overweight
Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials.
- Trial name
- NCT07619508
- Testing
- Tirzepatide, Semaglutide
- Where
- United States
- Volunteers
- 100,000 people
- Sponsor
- Brigham and Women's Hospital
Gestational Diabetes
Patterns and Glycaemic Endpoints for Diagnosing Gestational Diabetes
Gestational diabetes (GDM) develops during pregnancy and is becoming increasingly common. The condition is associated with adverse outcomes for mother and baby during both the pregnancy and delivery period.
- Trial name
- PAGED-GDM (NCT05981547)
- Testing
- Libre 3 continuous glucose monitoring sensor
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Portsmouth Hospitals NHS Trust
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