Clinical trials: Diabetes Mellitus Risk
Type 1 Diabetes, Type 2 Diabetes
Clinical and Economic Benefits of Cardiovascular Risk Management by a Dietician in Type 2 Diabetes Patients
Worldwide, health systems and practitioners are facing obesity epidemics. High blood pressure, dyslipidemia and diabetes prevalence will explode during the 21st century.
- Trial name
- GRC (NCT00444899)
- Testing
- Intensive treatment, Normal follow-up
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- Université de Sherbrooke
Prediabetic State
Mobile App for Risk Reduction of Type 2 Diabetes
The aim of this feasibility study is to investigate whether a full scale RCT on the efficacy of a mobile app for risk reduction on type 2 diabetes can be conducted in the way it is planned or whether it needs to be modified.
- Trial name
- NCT06117098
- Testing
- Mobile application, Group-based lifestyle intervention at a Healthy Lifestyle Centre + mobile application", Group-based lifestyle intervention
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo Metropolitan University
Pregnant Women, Diabetes Type 1
Factors Associated With Cesarean Delivery in Women With Type 1 Diabetes
Introduction : Cesarean rate varies from 45% to 73% in the literature in patient with diabetes type 1. Having a prior C-section is the most important risk factor.
- Conditions
- Pregnant Women, Diabetes Type 1, Cesrean Delivery
- Trial name
- NCT03538106
- Where
- France
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Overweight or Obesity
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in childbearing years.
- Trial name
- NCT05674799
- Testing
- NDPP-NextGen
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Diabetes Mellitus, Metabolic Syndrome
Effect of Bariatric Surgery "Digestive Adaptations III" on Cardiovascular Risk
Introduction- Primary prevention is the main strategy to control the global burden of cardiovascular disease. In clinical practice, food restriction represents a valuable preventive resource.
- Conditions
- Diabetes Mellitus, Metabolic Syndrome, Obesity, Atherosclerosis
- Trial name
- ADIII (NCT01581099)
- Testing
- Digestive Adaptations III surgery
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Diabetes Mellitus
Study of Raisins Versus Alternative Snacks in Patients With Type 2 Diabetes Mellitus
The objective of this study is to compare the effects of Raisins three times per day versus alternative snacks three times per day on blood sugar control and cardiovascular risk factors (weight, waist circumference, blood…
- Trial name
- NCT01677936
- Testing
- Raisins, Snacks
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Louisville Metabolic and Atherosclerosis Research Center
Type 2 Diabetes (T2DM), Hepatocellular Carcinoma (HCC)
HCC Risk and Monitoring in Patients With Type 2 Diabetes
Liver cancer is a significant malignancy in Taiwan. With the widespread implementation of antiviral therapies, hepatitis B and C-related liver cancer has gradually declined; however, metabolic dysfunction-associated liver cancer…
- Trial name
- GAAD-DM (NCT07675187)
- Testing
- GAAD score
- Where
- Taiwan
- Volunteers
- 2,400 people
- Sponsor
- National Taiwan University Hospital
Type 2 Diabetes, Overweight
Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular Risk
Investigators are building an empirical evidence base for real-world data through large-scale emulation of randomized controlled trials.
- Conditions
- Type 2 Diabetes, Overweight, Cardiovascular (CV) Risk
- Trial name
- TIRZSEMA-CVOT (NCT07096063)
- Testing
- Tirzepatide, Dulaglutide, Semaglutide
- Where
- United States
- Volunteers
- 887,132 people
- Sponsor
- Brigham and Women's Hospital
Ischemic Stroke, Transient Ischemic Attack
Liraglutide in Acute Minor Ischemic Stroke or High-risk Transient Ischemic Attack Patients With Type 2 Diabetes Mellitus
The purpose of this study is to assess the safety and efficacy of glucagon-like peptide-1 (GLP-1) analogue liraglutide in the treatment of acute minor stroke (National Institute of Health stroke scale, NIHSS ≤ 3) or high-risk…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Type 2 Diabetes Mellitus
- Trial name
- LAMP (NCT03948347)
- Testing
- Liraglutide
- Where
- China
- Volunteers
- 1,708 people
- Sponsor
- First Affiliated Hospital of Jinan University
Diabetes Mellitus, Type 2, Insulin Resistance
Determinants of Type 2 Diabetes Risk in Middle-aged Black South African Men and Women
There is little known about menopause in African women, whose phenotype differs to Caucasian women, and no data is available on middle-aged black South African men.
- Conditions
- Diabetes Mellitus, Type 2, Insulin Resistance, Menopause, Hiv
- Trial name
- NCT03408678
- Where
- South Africa
- Volunteers
- 1,025 people
- Sponsor
- University of Witwatersrand, South Africa
Diabetes, Hypercholesterolaemia
The Effect of Providing Genetic Risk Information on Lifestyle Behaviors in African Americans
Cardiovascular disease (CVD) is a major and persistent health disparity for African Americans. Linking GAINS is a randomized pilot and feasibility study designed to evaluate whether receiving genetic risk information early in a…
- Conditions
- Diabetes, Hypercholesterolaemia, Hypertension, Obesity Type 2 Diabetes Mellitus
- Trial name
- LINKING GAINS (NCT07833384)
- Testing
- Color Genomics Genetic Testing Panels
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Pre-diabetes, Diabetes Mellitus
Artificial Intelligence to Improve Cardiometabolic Risk Evaluation Using CT Scans
To validate the ability of the FatHealth algorithm to identify individuals with pre-diabetes and with type 2 diabetes mellitus
- Trial name
- ACRE-CT (NCT05058690)
- Testing
- Oral Glucose Tolerance Test
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Caristo Diagnostics Limited
Pre Diabetes
Behavioral Economics and Self-Determination Theory to Change Diabetes Risk (BEST Change)
Patients with prediabetes can significantly reduce their risk of developing type 2 diabetes mellitus (T2DM) by participating in a Diabetes Prevention Program (DPP) or using metformin, but very few patients with prediabetes engage…
- Trial name
- BEST (NCT04902326)
- Testing
- Automated educational text messages, Autonomy-supportive automated educational text messages, Financial incentives
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- University of Michigan
Type 2 Diabetes Mellitus (DM), Gastric Ultrasound
Preoperative Gastric Volume and High-Risk Gastric Content in Patients With Type 2 Diabetes Mellitus
This prospective observational study will evaluate adult patients with type 2 diabetes mellitus who are scheduled for elective surgery.
- Trial name
- NCT07842757
- Testing
- Preoperative Gastric Ultrasonography, Capillary Fasting Blood Glucose Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Atherosclerotic Cardiovascular Disease, Symptomatic Atherosclerosis
An Extension Trial of Inclisiran in Participants With Cardiovascular Disease and High Cholesterol
This clinical study was designed to assess the efficacy, safety, and tolerability of long-term dosing of inclisiran and evolocumab given as subcutaneous injections in participants with high cardiovascular risk and elevated…
- Conditions
- Atherosclerotic Cardiovascular Disease, Symptomatic Atherosclerosis, Type2 Diabetes, Familial Hypercholesterolemia
- Trial name
- ORION-3 (NCT03060577)
- Testing
- Inclisiran, Evolocumab
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 382 people
- Sponsor
- Novartis Pharmaceuticals
Prediabetes, Obesity (Body Mass Index >30 kg/m2)
Behavioral Approach for Latinas Addressing Nutrition, Cravings, and Eating Patterns to Prevent Type 2 Diabetes
Adapt the Regulation of Cues (ROC) treatment program for Latinas to see if it can treat prediabetes and prevent developing of Type 2 Diabetes and reduce weight.
- Trial name
- BALANCE (NCT07478263)
- Testing
- Regulation of Cues
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Behavior Change Interventions
Monocular-Camera-Based Mobile Exergame for Type 2 Diabetes Prevention
Exergames have demonstrated potential as effective interventions for promoting physical activity and preventing type 2 diabetes (T2D), particularly among older adults.
- Trial name
- NCT06950528
- Testing
- Control group, Kinect group, Monocular group
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Type 2 Diabetes, Cardiovascular Disease
Risk Factors of Incidence of Type 2 Diabetes and Cardiovascular Diseases---Shanghai Baoshan Study
Objective: Recruit 3 cohorts with 1000-1200 subjects each: people with normal glucose metabolism, impaired glucose regulation (IGR), and with Type 2 diabetes. To study the risk factors in development of type 2 diabetes.
- Trial name
- SBSS (NCT00949416)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Type 2 Diabetes
Noninvasive Methods in Diagnosing Coronary Heart Disease in Diabetic Patients
The purpose of this study is to investigate the prevalence of cardiac disease/coronary artery disease and diagnostic yield of different non-invasive methods in patients with type 2 diabetes 40-75 years of age at examination.
- Trial name
- NCT01179165
- Testing
- Diagnostic
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- Norwegian University of Science and Technology
Metabolic Syndrome
Impact of Exercise Training Intensity on Abdominal Visceral Fat and Risk Factors Associated With the Metabolic Syndrome
The purpose of this study is to determine if sixteen weeks of high intensity physical training is more effective than sixteen weeks of low intensity physical training in reducing abdominal fat and lowering risk factors associated…
- Trial name
- NCT00350064
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Virginia
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