Clinical trials: Diabetes Mellitus Risk
Chronic Hepatitis b, Non-alcoholic Fatty Liver Disease
Risk Factors for Hepatic Inflammation, Fibrosis and Prognosis in Patients With CHB and NAFLD
Chronic hepatitis B (CHB) affects an estimated 292 million people, and causes approximately 800,000 people deaths per year from liver-related complications including cirrhosis and hepatocellular carcinoma, remaining a major…
- Trial name
- NCT05766449
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Gestational Diabetes Mellitus
The Impact of Vitamin D Supplementation on Pregnant Women With the Risk of GDM
A clinical trial will be conducted in Chemical pathology department in collaboration with Gyne \&Obs department of PRH, IIMC over a period of 02 years w.e.f. December 15, 2023.
- Trial name
- NCT06139133
- Testing
- Vitamin D supplementation
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- IIMC, Riphah International University, Pakistan
Diabete Mellitus, Retina Vein Occlusion
Serum Cholinesterases, Paraoxonase, and Cardiovascular Risk After Intravitreal Bevacizumab
Bevacizumab, an anti-VEGF (vascular endothelial growth factor) agent used in the treatment of diabetic retinopathy and macular edema associated with retinal vein occlusion, is commonly administered in ophthalmology clinics…
- Conditions
- Diabete Mellitus, Retina Vein Occlusion, Age Macular Degeneration
- Trial name
- NCT07550777
- Testing
- blood test
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Diabetes Mellitus, Foot Ulcer, Diabetic
Prevention of Primary Foot Ulcers in High-risk Diabetes Patients
This is a primary prevention study which aims to assess reduction in the rate of diabetic foot ulcers in patients with high-risk diabetic feet using 3D printed insoles compared to standard care
- Conditions
- Diabetes Mellitus, Foot Ulcer, Diabetic, Primary Prevention
- Trial name
- PROFOUND (NCT03958539)
- Testing
- 3D printed insoles for normal footware
- Where
- United Kingdom
- Volunteers
- 900 people
- Sponsor
- Countess of Chester NHS Foundation Trust
Diabetes
Regulation of Hepatic Insulin Extraction
This study is in the area of Type 2 diabetes and genetics Healthy Volunteers and those with mild type 2 diabetes may be eligible to participate This study is searching for genes that may affect the body's processing/digestion of…
- Trial name
- RHIE (NCT00811044)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus, Type 2, Prediabetic State
Sleep for Health Study on the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk
This study tests whether providing cognitive behavioral therapy for insomnia (CBT-I) to people with prediabetes results in a reduction in glucose levels compared to a patient education control program.
- Conditions
- Diabetes Mellitus, Type 2, Prediabetic State, Sleep Initiation and Maintenance Disorders
- Trial name
- NCT06067139
- Testing
- SHUTi, Patient Education
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Kaiser Permanente
Diabetic Foot Ulcer
Custom Insole With Transcutaneous Electrical Nerve Stimulation on Clinical Outcomes of Diabetic Foot Ulcers
Diabetic foot ulcers (DFUs) are one of the serious complications of diabetes, typically resulting from neuropathy or peripheral arterial disease, and can often lead to amputation.
- Trial name
- NCT07109895
- Testing
- Standard Care Only, Custom Insole + Standard Care, TENS + Custom Insole + Standard Care
- Where
- Pakistan
- Volunteers
- 159 people
- Sponsor
- University of Lahore
Diabetes type1, Obesity
Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment
More than 40% of young adults with type 1 diabetes (T1D) also have overweight or obesity. Each of these diagnoses increase the risk of adverse cardiovascular events.
- Trial name
- NCT06411210
- Testing
- Semaglutide Pen Injector
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Yale University
Type 2 Diabetes Mellitus
Does Saxagliptin Reduce the Risk of Cardiovascular Events When Used Alone or Added to Other Diabetes Medications
The purpose of this study is to determine whether saxagliptin can reduce the risk of cardiovascular events when used alone or added to other diabetes medications
- Trial name
- SAVOR- TIMI 53 (NCT01107886)
- Testing
- Saxagliptin
- Where
- 536 sites in United States, Argentina and 25 more
- Volunteers
- 18,206 people
- Sponsor
- AstraZeneca
Hypertension, Diabetes Mellitus
Dissemination of the Cardiovascular Risk Service
The objective of this study is to evaluate the implementation of of a remote, pharmacist-led cardiovascular risk service (CVRS) in 12 large, organizationally and culturally diverse hospitals and health-systems, many with high…
- Trial name
- CVRSLive (NCT03660631)
- Testing
- CVRS Intervention
- Where
- 14 sites in United States
- Volunteers
- 542 people
- Sponsor
- Korey Kennelty
Obesity, Childhood, Nutrition
Nutrition Recommendation Intervention trialS in Children's Healthcare
NuRISH is a suite of clinical trials for children from low-income families which will determine whether primary healthcare prescription for: 1) Optimal breastfeeding with support from a mobile lactation consultant vs.
- Conditions
- Obesity, Childhood, Nutrition, Health Risk Behaviors, Breastfeeding
- Trial name
- NuRISH (NCT05477628)
- Testing
- Childcare Navigator, Lactation Consultant, Lactation Consultant Support and Childcare Navigator Support
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Cancer
Risk Evaluation of cAncers in Chinese diabeTic Individuals: a lONgitudinal Study
Phase 1: Baseline investigation (nation-wide survey) Aims: To investigate whether diabetes and prediabetes is a risk factor for cancers of all sites as well as for specific type of cancer, such as breast and colorectal cancer.
- Trial name
- REACTION (NCT01506869)
- Where
- China
- Volunteers
- 200,000 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Coronary Artery Disease, Diabetes Mellitus
Effects of RF on Clopidogrel Resistance in Patients at High Cardiovascular Risk
Ramadan fasting (RF) has been shown to be associated with vascular and metabolic disorders including glycemic control and lipid profile. It may also alter pharmacologic properties of some medications.
- Trial name
- RFeCloR (NCT02624583)
- Where
- 2 sites in Tunisia
- Volunteers
- 98 people
- Sponsor
- University of Monastir
Pre-Diabetes
Genetic Physiopathology and Evolution of Type 2 Diabetes
There are few longitudinal studies in the Caucasian population and even less in the Italian population in subjects with impaired glucose regulation to allow: 1. An estimate of the rate of conversion to type 2 diabetes; 2.
- Trial name
- GENFIEV (NCT00879801)
- Where
- Italy
- Volunteers
- 1,017 people
- Sponsor
- University of Pisa
Diabetes Mellitus, Diabetes, Gestational
Recent GDM Lifestyle Intervention
Women with a history of gestational diabetes (GDM) have a substantially increased risk of developing type 2 diabetes. In fact, 50-70% of these women will go on to develop type 2 diabetes within the 20 years following their…
- Trial name
- LIFe (NCT01910805)
- Testing
- Lifestyle and Risk Assessment class
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Metabolic Syndrome, Diabete Type 2
Metformin Versus Vildagliptin in Reducing Risk of Metabolic Syndrome Complications Progression
Several crosssectional and prospective studies have shown that metabolic syndrome and its related components are associated with both prevalent and incident CKD .
- Conditions
- Metabolic Syndrome, Diabete Type 2, Kidney Insufficiency
- Trial name
- NCT04485845
- Testing
- Vildagliptin, Captopril Tablets, MetFORMIN 500 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Cairo University
Dietary Intervention, Pre Diabetes
Acceptability, Feasibility and Effectiveness of a Worksite Intervention to Lower Cardiometabolic Risk in South Africa
As an important way to translate cardiovascular disease prevention efforts, worksite interventions can facilitate healthy food choices, health education, and social support.
- Conditions
- Dietary Intervention, Pre Diabetes, Hypertension
- Trial name
- NCT04494139
- Testing
- Behavioral and Canteen intervention, Canteen
- Volunteers
- 350 people
- Sponsor
- Durban University of Technology
Diabetic Foot Ulcer, Peripheral Arterial Disease
A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers.
This study is evaluating whether a therapeutic ultrasound device can improve blood flow to the leg with diabetic foot ulcer (DFU).
- Conditions
- Diabetic Foot Ulcer, Peripheral Arterial Disease, Wound; Foot
- Trial name
- Dulcet (NCT05145439)
- Testing
- VibratoSleeve Therapeutic Ultrasound Device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vibrato Medical, Inc.
Atherosclerotic Cardiovascular Disease, Childhood Diabetes Mellitus
Atherosclerotic Cardiovascular Risk in Childhood and Teen-age Onset Diabetes
For children and adolescents with diabetes, the pathological process of atherosclerotic cardiovascular disease(ASCVD) can exist in early childhood and progress rapidly to subclinical ASCVD.
- Conditions
- Atherosclerotic Cardiovascular Disease, Childhood Diabetes Mellitus, Juvenile Diabetes
- Trial name
- NCT05294653
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Cardiovascular Diseases, Diabetes Mellitus
Women's Healthy Lifestyle Project: Cardiovascular Risk Factors and Menopause
To determine if the increase in low density lipoprotein (LDL) cholesterol at the time of menopause could be ameliorated or prevented by an intensive dietary intervention.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Heart Diseases, Hypercholesterolemia
- Trial name
- NCT00000532
- Testing
- diet, fat-restricted
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
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