Clinical trials: Diabetes Mellitus Risk
Prediabetes, Depressive Symptoms Mild to Moderate in Severity
Mindfulness-based Personalized Health Planning for Reducing Risk of Heart Disease and Diabetes
The purpose of this study is to compare the effectiveness of educational and lifestyle intervention programs aimed at reducing fasting blood sugar and emotional distress in adults with prediabetes.
- Trial name
- AWARENESS (NCT01430221)
- Testing
- Mindfulness-based Personalized Health Planning, Structured & Guided Education
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duke University
Diabete Mellitus
Effect of Tributyrin Supplementation on Glycemic Control, Inflammation, and Cardiovascular Risk in Patients With Type 2 Diabetes
This study evaluates the effectiveness and safety of tributyrin supplementation in patients with type 2 diabetes mellitus (T2DM) who are at increased risk of cardiovascular disease.
- Trial name
- NCT07503548
- Testing
- tributyrin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Diabetes Mellitus, Type 2, Obesity
Genetic and Epigenetic Risk of T2D in the UAE
T2D is a global public health crisis and a threat to socioeconomic development of all nations, particularly in developing countries.
- Trial name
- NCT04270097
- Where
- United Arab Emirates
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London Diabetes Centre
Type 2 Diabetes Mellitus, Insulin Resistance
Impact of Overfeeding and Following Exercise Training in Individuals With and Without Increased Risk of Type 2 Diabetes
Low birth weight (LBW), a marker of impaired fetal growth is an independent and strong risk factor for type 2 diabetes (T2D). A western lifestyle characterized by a surplus of calories, and/or a low physical activity level…
- Conditions
- Type 2 Diabetes Mellitus, Insulin Resistance, Dyslipidemia
- Trial name
- NCT02982408
- Testing
- High carbohydrate overfeeding, Exercise, Normal physical activity
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Type 2 Diabetes Mellitus (T2DM)
Phase III Trial of SGLT2 Inhibitor and Thiazolidinedione Fixed-Dose Combination vs. Monotherapy in Type 2 Diabetes Patients on Metformin
This clinical trial is studying whether combining two commonly used diabetes medications into a single pill works better than taking them separately for people with type 2 diabetes who are already on metformin.
- Trial name
- CONTROL (NCT07057479)
- Testing
- Fixed-dose combination of SGLT2 inhibitor and thiazolidinedione, Control Group 1 Intervention - SGLT2 inhibitor monotherapy, Control Group 2 Intervention - Thiazolidinedione monotherapy
- Where
- Brazil
- Sponsor
- Eurofarma Laboratorios S.A.
Diabetes, PreDiabetes
Study of Diabetes' Risk Factors and Accelerated Aging According to Socio-economic Status in a Population From the North of France
Populations in precarious situations or with low socio-economic status have an increased risk of diabetes and accelerated aging.
- Trial name
- PREVENDIAB (NCT05717491)
- Testing
- Biological analysis, Physical examination and Questionnaires, Physical examination and Questionnaires
- Where
- France
- Volunteers
- 2,014 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Type 2 Diabetes (T2DM), Metabolic Dysfunction-Associated Steatotic Liver Disease
Cardiovascular Risk in T2DM With MAFLD: A Cohort Study
This study aims to address the following key scientific question by establishing a large-scale, high-standard clinical cohort: the independent contribution of MASLD and its progression to liver fibrosis on cardiovascular outcomes…
- Trial name
- NCT07706010
- Where
- China
- Volunteers
- 7,000 people
- Sponsor
- The Affiliated Hospital of Hangzhou Normal University
Sleep, Insulin Resistance
Glucose Metabolism and Sleep in People With Family History of Type 2 Diabetes.
The use of sugar and starch-like foods for energy (carbohydrate metabolism) changes when people sleep. However, it is still not known if differences in the amount of nighttime sleep have an effect on the carbohydrate metabolism…
- Conditions
- Sleep, Insulin Resistance, Type 2 Diabetes
- Trial name
- NCT00720889
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Hyperglycemia, Diabetes Mellitus
Early Detection Initiative for Pancreatic Cancer
The Early Detection Initiative for Pancreatic Cancer is a multi-center prospective study to determine if algorithm-based screening in patients with glycemically defined new onset hyperglycemia and diabetes has the potential for…
- Conditions
- Hyperglycemia, Diabetes Mellitus, Pancreas Ductal Adenocarcinoma
- Trial name
- EDI (NCT04662879)
- Testing
- Enriching New-onset Diabetes for Pancreatic Cancer (ENDPAC) score, Abdominal imaging
- Where
- 2 sites in United States
- Volunteers
- 8,869 people
- Sponsor
- Pancreatic Cancer Action Network
Type 2 Diabetes
Vitamin D Supplementation on Cardiovascular Risk Factors
The purpose of the present pilot study is to determine the effect of vitamin D supplementation (4000 IU or 6000 IU once daily for 6 months) on reducing heart disease risk and in improving blood glucose control in type 2 Diabetes…
- Trial name
- NCT01412710
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Florida International University
Discriminate Obese Children at Risk for Diabetes.
Circulating microRNAs for Discriminating Obese Preschoolers at Risk of Diabetes
Childhood obesity certainly increases susceptibility to type 2 diabetes (T2D) in adulthood. Recently, microRNAs (miRNAs) are closely related to various diseases and have been suggested as valuable biomarkers.
- Trial name
- NCT02843139
- Where
- China
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Prediabetes
Efficacy of Diacylglycerol Oil on Metabolic Risk Factors in Prediabetes
This study will implement a four-week dietary intervention among middle-aged and older adults with pre-diabetes. Participants assigned to the intervention arm will replace their usual cooking oil with diacylglycerol (DAG) oil…
- Trial name
- NCT07289880
- Testing
- Diacylglycerol oil, Colza Oil
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangdong Pharmaceutical University
Type1diabetes
HIT on Hypoglycaemic Risk in T1D
There is clear evidence that regular exercise improves wellbeing and reduces the risk of diabetes related complications in people with type 1 diabetes. However, many people with type 1 diabetes do not exercise regularly.
- Trial name
- NCT05044442
- Testing
- moderate intensity continous training, high intensity interval training
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Diabetes Mellitus, Insulin-Dependent
Genetic and Environmental Risk Factors of Type 1 Autoimmune Diabetes and Its Early Complications
The aim of this study is to complete the identification of genetic factors (G) and to undertake the search of environmental factors (E) predisposing to type 1 diabetes (T1D) by constituting a cohort of 3500 T1D patients and a…
- Trial name
- ISIS-DIAB (NCT02212522)
- Testing
- Collect of environmental data on T1D patients before diagnosis, Collect of blood samples for DNA extraction and genetic characterization (GWAS), Collect of clinical data on the disease and its evolution
- Where
- France
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 1 Diabetes Mellitus
Prematurity Prevalence Among T1D Patients and Its Characteristics Compared With Premature-born Non-diabetic Patients
The aims of this study are: 1. To assess the prevalence of prematurity, especially early prematurity, among T1D patients, and compare it to the prematurity prevalence among the non-diabetic general population in Israel. 2.
- Trial name
- T1Dpremies (NCT02929953)
- Testing
- chart review
- Where
- Israel
- Volunteers
- 3,600 people
- Sponsor
- Assaf Harofeh MC
Pre-Diabetes, Diabetes
A1c FIT TEST: An Epidemiological Study Correlating Hemoglobin A1c With Results of the Air Force Physical FITness TEST.
The purpose of this study is to evaluate the prevalence of pre-diabetes and diabetes among those Air Force personnel who have not passed the Air Force physical fitness test (AFPT) and to evaluate the usefulness of the AFPT as a…
- Conditions
- Pre-Diabetes, Diabetes, Cardiovascular Risks
- Trial name
- NCT01301339
- Where
- United States
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
Pre Diabetic
How Fig Polyphenols Affect Blood Sugar and Insulin Levels After Eating in Adults at Risk for Diabetes
The study purpose is to understand how the body absorbs and metabolizes nutrient-like components in dried figs called polyphenols over 24 hours.
- Trial name
- FG (NCT07625046)
- Testing
- Fig, Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Type 2 Diabetes, Vascular Diseases
Phenotyping Individuals With Neo-diagnosed Type 2 Diabetes at Risk for All-cause Mortality
Prevalence of type 2 diabetes (T2D) is increasing worldwide over the last two decades; in these patients the rate of all-cause and cardiovascular (CV) mortality is several folds higher than in the general population, configuring…
- Conditions
- Type 2 Diabetes, Vascular Diseases, Cardiac Disease
- Trial name
- NCT04453605
- Testing
- standard treatments
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Pisa
Type 2 Diabetes Mellitus (T2DM)
Effect of Tai Chi Versus Moderate-intensity Combined Exercise Training on Cardiovascular Health and Physical Functional Performance in Older Men and Women With T2DM: the Tai Chi Intervention for Diabetes Management During Aging (TIDA) Study
This randomized, single-blind, controlled clinical trial compares the effects of a 12-week Tai Chi program versus moderate-intensity combined exercise (MICE) training on cardiovascular health, glycemic control, and physical…
- Trial name
- TIDA (NCT07131761)
- Testing
- Tai chi, Moderate-Intensity Combined Exercise (MICE), Control ( No Exercise )
- Volunteers
- 66 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Diabetes Mellitus, Type 1
Insulin-Glucose-Glucagon Network: Defining a Type 1 Diabetes Progression Index
The type 1 Diabetes (T1D) TrialNet Pathway To Prevention (PTP) Study assesses and recruits at-risk subjects into clinical trials aimed at preventing the development of full blown T1D.
- Trial name
- NCT02663661
- Testing
- Metabolic Challenge Admission, CGM home test
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Virginia
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.