Clinical trials: Diabetes Mellitus Risk
Diet Modification, Substance Use Disorders
The Impact of a Parenting Intervention on Latino Youth Health Behaviors
The purpose of this study is to test if a parenting program can be used to prevent substance use among Latino youth and at the same time promote healthy eating.
- Conditions
- Diet Modification, Substance Use Disorders, Diabetes Mellitus Risk, Cardiovascular Risk Factor
- Trial name
- FPNG+ (NCT03517111)
- Testing
- Nutrition/substance use prevention, Substance use prevention only, Academic success program
- Where
- United States
- Volunteers
- 844 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Surgical Site Infection, Diabete Mellitus
Irrigation and Suction Trial to Prevent SSI
The study will be conducted on women with risk factors for SSI assigned to gynecological surgery with an open abdominal approach.
- Conditions
- Surgical Site Infection, Diabete Mellitus, Abdominal Hysterectomy
- Trial name
- I&S (NCT05611944)
- Testing
- Irrigation and suction through subcutaneus drains
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Diabetic Retinopathy, HIV
Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA®
To show the non-inferiority of EGRIFTA® vs. placebo in the development or progression of Diabetic Retinopathy in HIV-infected subjects with concomitant abdominal lipohypertrophy and Type 2 diabetes mellitus (T2DM).
- Trial name
- NCT01591902
- Testing
- Tesamorelin
- Where
- 24 sites in United States
- Volunteers
- 129 people
- Sponsor
- Theratechnologies
Diet, Cooking
Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease
Background: The risk of heart disease among African Americans is still common despite a greater understanding of the disease and better approaches to managing it.
- Trial name
- NCT04305431
- Testing
- Cooking Intervention
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Perioperative Myocardial Injury
Perioperative Copeptin: Predictive Value and Risk Stratification in Patients Undergoing Major Surgery
Observational cohort study examining the perioperative course of copeptin in patients undergoing elevated-risk surgery.
- Trial name
- NCT02687776
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 517 people
- Sponsor
- University Hospital, Basel, Switzerland
Diabetes Mellitus, Non-Insulin-Dependent
The ORIGIN Trial (Outcome Reduction With Initial Glargine Intervention)
The primary objectives of the ORIGIN study were: To determine whether insulin glargine-mediated normoglycemia can reduce cardiovascular morbidity and/or mortality in people at high risk for vascular disease with either Impaired…
- Trial name
- ORIGIN (NCT00069784)
- Testing
- insulin glargine (HOE901), omega-3 polyunsaturated fatty acids (PUFA), reusable pen device for insulin injection
- Where
- 40 sites in United States, Argentina and 38 more
- Volunteers
- 12,537 people
- Sponsor
- Sanofi
Major Coronary Event, Cerebrovascular Accident
CARDS Is Designed To Show If Lowering Cholesterol With Atorvastatin In Type 2 Diabetics Without CV Disease Reduces The Risk Of CV Events
A study to assess the efficacy of once daily atorvastatin 10 mg versus placebo on cardiovascular endpoints in patients with non-insulin-dependent diabetes mellitus (NIDDM) who have a history of either hypertension, retinopathy…
- Conditions
- Major Coronary Event, Cerebrovascular Accident, Coronary Artery Bypass Graft, Angina, Unstable
- Trial name
- CARDS (NCT00327418)
- Testing
- Atorvastatin
- Where
- 135 sites in United Kingdom
- Volunteers
- 2,800 people
- Sponsor
- Pfizer
Hypertension, Hypertension, Systolic
Treatment of Hypertension During Sleep
On the basis of new evidence on the relationship between achieved office blood pressure (BP) measurements (OBPM) and the risk of cardiovascular disease (CVD) morbidity and mortality documented in the SPRINT trial, the recent 2017…
- Trial name
- THADEUS (NCT03457168)
- Testing
- Treatment of elevated asleep SBP mean
- Where
- 9 sites in Spain
- Volunteers
- 5,320 people
- Sponsor
- University of Vigo
Pre-diabetes
Breaking up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes
Newly released guidelines recommend increased physical activity (PA) and reduced sedentary behaviors (SB) to improve glycemia and prevent the onset and progression of type 2 diabetes (T2D).
- Trial name
- BURST2D (NCT05041491)
- Testing
- BREAK, ONE
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Colorado, Denver
type1diabetes, Obesity
Physiologic Markers of Cardiometabolic Risk in People With Type 1 Diabetes
More than 40% of young adults with type 1 diabetes (T1D) also have overweight or obesity. Each of these diagnoses increase the risk of adverse cardiovascular events.
- Trial name
- NCT06105931
- Testing
- Hyperinsulinemic-euglycemic clamp, High Fat Mixed Meal Tolerance Test
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Cerebral Stroke, Thrombosis, Deep Vein
A Study of Adverse Events and Suspected Adverse Drug Reactions in Patients Under Apixaban for Prevention of Stroke and Systemic Embolism With Non-Valvular Atrial Fibrillation and Venous Thromboembolic Events in Patients Who Have Undergone Elective Hip or Knee Replacement Surgery
To characterize and analyze the number, type and incidence of adverse events/suspected adverse drug reactions in patients treated with Apixaban, according to therapeutic indications approved in Mexico.
- Conditions
- Cerebral Stroke, Thrombosis, Deep Vein, Pulmonary Embolism
- Trial name
- NCT03804125
- Sponsor
- Pfizer
Obesity, Morbid, Hypertension
Comparison of Extremely Obese Patients Undergoing Gastric Sleeve Surgery
By the comparison of the preoperative and postoperative data of approximately 160 patients undergoing gastric sleeve surgery, we try to draw conclusions about the effectiveness of gastric sleeve surgery, expected complication…
- Conditions
- Obesity, Morbid, Hypertension, Diabetes Mellitus, Type 2
- Trial name
- NCT05929170
- Where
- Hungary
- Volunteers
- 160 people
- Sponsor
- University of Pecs
Heart Failure, Diabetes Mellitus
Targeted Assessment in High-Risk paTients With dIAbetes to ideNtify Undiagnosed Heart Failure
This is a prospective, multicentre, unblinded, randomised, controlled trial. The primary aim is to assess a targeted screening strategy to detect undiagnosed heart failure in high-risk patients with diabetes.
- Conditions
- Heart Failure, Diabetes Mellitus, Type 1 Diabetes, Type 2 Diabetes
- Trial name
- TARTAN-HF (NCT05705869)
- Testing
- NT-proBNP
- Where
- 2 sites in United Kingdom
- Volunteers
- 706 people
- Sponsor
- NHS Greater Glasgow and Clyde
Diabetes Mellitus Type 2
A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus
This double-blind, parallel, two-arm study will evaluate the potential to reduce cardiovascular risk, the tolerability and long-term safety profile of aleglitazar compared to placebo on top of standard care in patients with…
- Trial name
- NCT01042769
- Testing
- Aleglitazar
- Where
- 810 sites in United States, Argentina and 25 more
- Volunteers
- 7,226 people
- Sponsor
- Hoffmann-La Roche
Diabetes, STEMI
Sweetheart-Register: Risk Management of Diabetics with Acute Myocardial Infarction
The Sweetheart register (Risk management of Diabetics with acute myocardial infarction) documents both the prevalence of pathologic glucose metabolism in consecutive high-risk patients with STEMI and NSTEMI in daily hospital…
- Conditions
- Diabetes, STEMI, NSTEMI, Myocardial Infarction
- Trial name
- Sweetheart (NCT01197742)
- Where
- 2 sites in Germany
- Volunteers
- 2,772 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
PreDiabetes
Precision Medicine for Preventing Type 2 Diabetes: a Step Forward
The prevalence of type 2 diabetes (T2D) has been rising rapidly with an increased burden to the healthcare system. As such T2D prevention is highly recommendable, and, theoretically, it can definitely be successful.
- Trial name
- PRE-MED2 (NCT05147961)
- Testing
- Digital Health, Standard care
- Where
- 2 sites in Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Hyperlipemia, Hypertension
A Text Message Intervention to Promote Health Behaviors in Cardiac Risk Conditions
This is a randomized pilot trial to examine the feasibility, acceptability, and preliminary efficacy of an adaptive text message intervention (TMI) to promote well-being and health behavior adherence in 60 patients with two or…
- Conditions
- Hyperlipemia, Hypertension, Type2 Diabetes
- Trial name
- NCT04382521
- Testing
- Text Message Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Massachusetts General Hospital
Obesity, Pre-diabetes
Chromium Effects on Insulin and Vascular Function in People at Risk for Diabetes
The purpose of this study is to investigate the effects of Chromium on glucose tolerance and endothelial function in people at risk for type II diabetes.
- Conditions
- Obesity, Pre-diabetes, Insulin Resistance, Impaired Glucose Tolerance
- Trial name
- NCT00067626
- Testing
- Chromium
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Griffin Hospital
Diabetes Mellitus, Type 2
A Study of People With Type 2 Diabetes Who Have Diseases That Affect the Heart and Blood Vessels. The Study Will Also Look at the Treatment of a Group of These People in Hospitals in Portugal
This study aims to estimate the number of patients with cardiovascular disease and risk factors in patients who had been diagnosed with type 2 diabetes mellitus.
- Trial name
- PICT2RE (NCT03797885)
- Testing
- No treatment given
- Where
- 14 sites in Portugal
- Volunteers
- 730 people
- Sponsor
- Novo Nordisk A/S
Diabetic Foot, Diabetes Mellitus
The Role of Extrinsic Foot Muscles Chances in Determining the Risk of Diabetic Foot Ulcer
Many foot and lower limb disorders resulting from diabetes, such as deformity, muscle weakness, reduced range of motion, stiffness of connective tissue, amount of oxygenation, functional capacity, poor balance and coordination…
- Trial name
- NCT06736210
- Testing
- Muscle Elastic Properties Measurement, Muscle Oxygen Saturation (SmO2), Plantar Pressure Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
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