Clinical trials: Diabetes Mellitus Risk
Type 1 Diabetes (T1D), Food Insecurity
Pilot of Food Is Medicine Interventions to Reduce Cardiovascular Disease Risk in Children With Food Insecurity and Diabetes
Study Design: This two-arm parallel trial will randomize 12 families to receive 6-weeks of medically tailored meals or produce prescriptions. Both groups will receive nutrition coaching, weekly during the intervention.
- Trial name
- NCT07590817
- Testing
- Produce prescription, Medically tailored meal kits, Nutrition Coaching
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Katelyn Fox
Diabetes
Acute Impact of Intramuscular (IM) Aripiprazole and Olanzapine on Insulin Resistance in High Risk Prediabetics
Antipsychotic medicines used to treat mental illnesses have been associated with effects on blood sugar control. Laboratory studies have shown that certain medications in particular may alter how insulin works.
- Trial name
- NCT01411930
- Testing
- Intramuscular olanzapine, aripiprazole, Intramuscular aripiprazole, olanzapine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Veterans Medical Research Foundation
Type 1 Diabetes, Type 2 Diabetes
Clinical and Economic Benefits of Cardiovascular Risk Management by a Dietician in Type 2 Diabetes Patients
Worldwide, health systems and practitioners are facing obesity epidemics. High blood pressure, dyslipidemia and diabetes prevalence will explode during the 21st century.
- Trial name
- GRC (NCT00444899)
- Testing
- Intensive treatment, Normal follow-up
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- Université de Sherbrooke
Diabetes, Chronic Kidney Disease
The Alberta Vascular Risk Reduction Community Pharmacy Project: RxEACH
Cardiovascular disease (disease of the heart and blood vessels) is one of the leading causes of death in Canada. It also carries a financial burden on the Canadian economy with a yearly cost close to $21 billion divided between…
- Conditions
- Diabetes, Chronic Kidney Disease, Established Atherosclerotic Vascular Disease, Framingham Risk Score More Than 20 Percent
- Trial name
- RxEACH (NCT01979471)
- Testing
- Advanced Care
- Where
- Canada
- Volunteers
- 723 people
- Sponsor
- University of Alberta
CKD - Chronic Kidney Disease, Diabetes Mellitus Type 2
Evaluation of the Risk of Heart Failure in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus
The goal of this study, performed entirely with computer programs, is to learn if using a combination of two drugs works better than using one alone, in the treatment of people with chronic kidney disease and type 2 diabetes…
- Trial name
- NCT07719621
- Where
- Spain
- Volunteers
- 100,000 people
- Sponsor
- Aeterna Medical Solutions SL
Gestational Diabetes Mellitus (GDM)
Implementation and Evaluation of Bump2Baby and Me+ Programme for Gestational Diabetes Mellitus in Routine Maternity Care Setting.
Gestational diabetes mellitus (GDM) affects approximately 1 in 7 pregnancies globally and is associated with significant short and long-term health consequences for both mothers and infants.
- Trial name
- B2B&ME+ (NCT07189221)
- Testing
- Life Style Intervention
- Volunteers
- 3,600 people
- Sponsor
- University College Dublin
Diabetes Mellitus Type 2
Rate of Change of HbA1c (dx/dt) May Predict Progression to Type 2 DM
The investigators hypothesize that the HbA1c shows a rising trend in pre-diabetics and normal population with risk factors of developing type 2 DM.
- Trial name
- NCT01315808
- Where
- United States
- Volunteers
- 542 people
- Sponsor
- Wyckoff Heights Medical Center
Hypertension
Atenolol Exposure as Risk for Adverse Metabolic Responses to Beta Blockers
The researchers hypothesize that the impact of increasing systemic exposure to atenolol leads to increased risk for adverse metabolic effects from atenolol therapy in hypertension.
- Trial name
- NCT00607347
- Testing
- Glucose
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Florida
Obesity and Type 2 Diabetes, Metabolic Diseases
Effects of HIIT vs. TRE on Type 2 Diabetes Risk
The primary aim of this randomized controlled trial is to examine the effects of a 4-week high-intensity interval training (HIIT) and time-restricted eating (TRE) intervention on cardiometabolic biomarkers in adolescents and…
- Conditions
- Obesity and Type 2 Diabetes, Metabolic Diseases, High-intensity Interval Training, Time-restricted Eating
- Trial name
- NCT07215533
- Testing
- High-intensity interval training, Time-restricted eating
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Obesity, Pre-diabetes
Evaluation of Lifestyle Interventions to Treat Elevated Cardiometabolic Risk in Primary Care
The purpose of the E-LITE Study is to evaluate the feasibility and potential effectiveness of two lifestyle interventions in a community based primary care setting.
- Conditions
- Obesity, Pre-diabetes, Metabolic Syndrome
- Trial name
- E-LITE (NCT00842426)
- Testing
- Self-management program (SM), Care management program (CM)
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Palo Alto Medical Foundation
Chronic Kidney Diseases, Type 2 Diabetes Mellitus
Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa
Chronic kidney disease (CKD) is associated with increased cardiovascular morbidity and mortality. The prevalence of CKD is increasing worldwide and is assumed to also dramatically increase in Sub-Saharan Africa (SSA).
- Conditions
- Chronic Kidney Diseases, Type 2 Diabetes Mellitus, Arterial Hypertension, Obesity
- Trial name
- RenalTWO (NCT05881447)
- Where
- Tanzania
- Volunteers
- 1,200 people
- Sponsor
- Swiss Tropical & Public Health Institute
Psychological Distress, Eating Disorders
Psychological Factors and Self-Care Behaviors in Spanish Youth With Type 1 Diabetes: Age- and Sex-Based Comparisons and Associations
This is a multicenter, observational, cross-sectional study of young people aged 10 to 25 with type 1 diabetes in Spain, affiliated with a diabetes association or federation.
- Conditions
- Psychological Distress, Eating Disorders, Self Care, Type 1 Diabetes Mellitus (T1DM)
- Trial name
- SPAIN-T1DM (NCT07452393)
- Where
- Spain
- Volunteers
- 115 people
- Sponsor
- University of Alicante
Gestational Diabetes, Pregnancy, High Risk
The Effect of Home Midwifery Care Given to Pregnant Women Diagnosed With Gestational Diabetes on Attitudes and Self-Care
Since gestational diabetes carries the risk of serious complications for the mother and fetus, it is very important to follow up the pregnancy carefully and consciously.
- Trial name
- NCT05670769
- Testing
- Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Overweight and Obesity, PreDiabetes
Clinical Effectiveness of Body Fat Distribution Imaging in Real-World Practice: The BODY-REAL Study
The overall goal is to determine the real-world feasibility and utility of body fat imaging using rapid MRI to enhance risk perception, induce behavioral change, and improve clinical outcomes in overweight and obese individuals.
- Conditions
- Overweight and Obesity, PreDiabetes, Type 2 Diabetes, Cardiovascular Risk Factor
- Trial name
- BODY-REAL (NCT04763772)
- Testing
- Body Fat Distribution Imaging Report, Basic Weight Information, Patient Provided
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University Hospitals Cleveland Medical Center
Diabete Type 2
Peel Family Diabetes Prevention Program
The goal of this Hybrid Type 2 effectiveness-implementation pilot randomized controlled trial is to assess the feasibility and preliminary effectiveness of a community-based wellness coaching intervention (the intervention) to…
- Trial name
- Peel FDPP (NCT07675551)
- Testing
- Family Dyad Health and Wellness Coaching Session, Educational Material
- Where
- 2 sites in Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Trillium Health Partners
Diabetic Foot
Repeated Educational Intervention for the Prevention of Diabetic Foot Ulcers in High-risk Patients
Following a prior observation that a brief structured group educational intervention is effective for the prevention of diabetic foot ulcers in high-risk patients, but that the efficacy decreases over the time, this study is…
- Trial name
- NCT03555656
- Testing
- Repeated intervention, Single session
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Type 2 Diabetes
Does the Hematopoietic Stem Cell Govern Residual Inflammatory Cardiovascular Risk in Type 2 Diabetes
To study the effect of type 2 diabetes (T2D) on vascular wall inflammation and hematopoietic stem cell composition in vivo, and whether these changes can be reversed with glucagon like peptide 1 receptor (GLP1R)-agonism.
- Trial name
- DOTAFLAME (NCT05597202)
- Testing
- Semaglutide, 2.0 mg/mL
- Where
- Netherlands
- Volunteers
- 22 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Diabetes Mellitus, Type 2, Metabolic Syndrome
Randomized Control Trial for Overweight Employees in Worksites
Impact of lifestyle intervention in at-risk Asian Indians at worksite remains largely unexplored. The aim of this study was to assess impact of the multi-component interventions on body weight, body fat patterning and…
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome, Lifestyle Risk Reduction
- Trial name
- NCT03249610
- Testing
- Lifestyle intervention
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Obesity, Type 2 Diabetes
Strength Training and Nutrition Development for African American Youth
The investigators are conducting an intervention study to examine the effects of a 16-week exercise and diet interventions on prevention of disease, specifically type 2 diabetes and heart disease, in African American youth.
- Conditions
- Obesity, Type 2 Diabetes, Cardiovascular Risk, Cancer
- Trial name
- STAND (NCT01441323)
- Testing
- Nutrition, Strength Training & Nutrition
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Diabetes, Diabetes Mellitus
The Impact of the Self-efficacy Building Nursing Program on Foot Self-care Confidence and Perceived Risk of Diabetes-related Foot Complications Among Diabetic Elderly Patients: A Randomized Virtual Based Trial
Abstract Background: Diabetes-related foot complications are a major cause of morbidity among elderly patients with diabetes, often exacerbated by inadequate self-care practices and low self-efficacy.
- Conditions
- Diabetes, Diabetes Mellitus, Foot Care
- Trial name
- foot self-care (NCT06973850)
- Testing
- The Self-Efficacy Building Nursing Program
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
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