Clinical trials: Diabetes Mellitus Risk
Schizophrenia, Schizoaffective Disorder
Efficacy Study of Panax Ginseng to Boost Antipsychotics Effects in Schizophrenia
The objective of the study is to determine whether Panax Ginseng with multiple interactions with key components of brain signaling pathway, can augment the effects of antipsychotics in Schizophrenia.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Tardive Dyskinesia, Insulin Resistance
- Trial name
- NCT00401089
- Testing
- Panax Ginseng
- Where
- 4 sites in Canada, United Kingdom
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cardiovascular Diseases
Assessing the Effectiveness of Concurrent Peer Review for Patients With Cardiovascular Disease and Diabetes
We will assess the impact of concurrent peer review vists on blood pressure, cholesterol and diabetes control. Concurrent peer review (CPR) visits refer to special offic visits by patients to a clinician (physician, nurse…
- Trial name
- NCT00508014
- Testing
- Usual Care, Concurrent Peer Review visit
- Where
- United States
- Volunteers
- 727 people
- Sponsor
- University of Rochester
Stress, Blood Sugar; High
Daily Blood Glucose Trends in Patients at Risk for Diabetes
The goal of this study is to learn about the relationship between blood sugar, diet, stress, and metabolic parameters including waist circumference, body mass index (BMI), cholesterol levels and blood pressure in patients at risk…
- Conditions
- Stress, Blood Sugar; High, Cholesterol, Elevated, Diet Habit
- Trial name
- NCT06000735
- Testing
- 7-Day Continuous Glucose Monitoring with Abbott Freestyle Libre 2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Karol E. Watson, MD
Cardiometabolic Health, Pregnancy Related
Cardiometabolic Health in First Time Pregnancy
Women who experience placental complications (syndromes) during pregnancy, such as pre-eclampsia (high blood pressure and kidney problems), gestational hypertension (high blood pressure during pregnancy) and fetal growth…
- Conditions
- Cardiometabolic Health, Pregnancy Related, Diabetes, Placental; Syndrome, Dysfunction
- Trial name
- POPPY (NCT05856318)
- Where
- 7 sites in United Kingdom
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Diabetes Mellitus, Cardiovascular Diseases
10-year Risk Prediction Models of Complications and Mortality of DM in Hong Kong
Diabetes Mellitus (DM) is a well-recognized public health issue worldwide. DM can lead to many complications resulting in morbidity and mortality, approximately 70% of DM related deaths were attributed to cardiovascular diseases…
- Conditions
- Diabetes Mellitus, Cardiovascular Diseases, Mortality, Primary Health Care
- Trial name
- NCT03299010
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 141,516 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Prediabetic State, Metabolic Syndrome
Effects of Sweetener Consumption on Risk Factors for Heart Disease in Prediabetic Subjects
The aim of this prospective interventional study is to investigate the metabolic effects of consuming artificial and natural sweeteners in persons with prediabetes.
- Conditions
- Prediabetic State, Metabolic Syndrome, Insulin Resistance, Thrombosis
- Trial name
- Sweetheart (NCT07377097)
- Testing
- Saccharin, Sucralose, Erythritol
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Diabetic Foot, Neuropathy
Effectiveness of Insoles Provided to Patients With Diabetes. A Longitudinal Randomized Controlled Study in Gothenburg
Introduction: Insoles and shoes are frequently prescribed to prevent foot ulcers in patients at risk of diabetes. A combination of neuropathy and foot deformities raises the risk from 1% to between 4-7% according to the Swedish…
- Conditions
- Diabetic Foot, Neuropathy, Quality of Life
- Trial name
- NCT01663519
- Testing
- Custom made insoles 35 shore, Prefabricated insoles, 55 shore Custom made insole
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Sahlgrenska University Hospital
Prediabetic State & High Risk Individuals on the Basis of Diabetes Risk Score
(Pakistan Diabetes Prevention Program PDPP)
The Karachi-based Pakistan Diabetes Prevention Study aims to address key issues in the prevention of type 2 diabetes. Approximately 20,000 people From four communities will be screened for diabetes risk factors using a…
- Trial name
- PDPP (NCT01530165)
- Testing
- Life style intervention
- Where
- Pakistan
- Volunteers
- 1,564 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Type 2 Diabetes, Liver Disease
Digital Behavioral Therapy to Reduce Diabetes and Liver Disease Risk
This clinical trial aims to find out if a digital behavioral program, delivered through the SIPPA digital therapeutics app, can help improve blood sugar control and lower the risk of liver fibrosis in adults with type 2 diabetes…
- Trial name
- SIPPA-QH_HHC-2 (NCT07032311)
- Testing
- Behavioral Treatment
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- SIPPA Solutions INC
Infections Joint Prosthetic, Overweight or Obesity
Antibiotic Prophylaxis in High-Risk Arthroplasty Patients
To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk…
- Conditions
- Infections Joint Prosthetic, Overweight or Obesity, MSSA Colonization, MRSA
- Trial name
- NCT04297592
- Testing
- Cephalexin, Doxycycline, Cefadroxil
- Where
- 2 sites in United States
- Volunteers
- 4,618 people
- Sponsor
- Mayo Clinic
Type-2 Diabetes
Liraglutide and Cardio-Metabolic Risk Markers
Incretin-based therapies have shown significant effects beyond those on glucose metabolism. We aim in the present study to evaluate the effects of liraglutide on several cardio-metabolic risk markers.
- Trial name
- NCT01715428
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Palermo
Metabolic Syndrome
Short-term Sugary Beverage Consumption on Glucose Control and Cardiovascular Disease Risk Factors
Our goal is to determine how the addition of sugar-sweetened beverages to the diet affects glucose control, cardiovascular disease risk factors, and pulmonary function in healthy, young adults.
- Trial name
- NCT04118257
- Testing
- Sugary beverage: Fruit juice, Sugary beverage: Soda, Control: Water
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Type 2 Diabetes Mellitus, Cardiovascular Risk Factor
Effectiveness of PRECEDE Model for Health Education on Changes and Level of Control in Patients With Type 2 Diabetes Mellitus
BACKGROUND: Individual health education is considered to be essential in the overall care of patients with type 2 diabetes (DM2), although there is some uncertainty regarding its metabolic control benefits.
- Trial name
- NCT01316367
- Testing
- PRECEDE HPE model, CHPE
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Hospital Carlos III, Madrid
Body Weight, Obesity
Meta Analysis of the Effect of a Low Glycemic Index Diet and Glycemic Load on Body Weight
A low glycemic index (GI) diet has been associated with improved glycemic control in type 2 diabetes patients and a reduced risk of cardiovascular disease (CVD).
- Conditions
- Body Weight, Obesity, Cardiovascular Diseases, Diabetes Mellitus, Type 2
- Trial name
- NCT02557022
- Testing
- GI and/or GL
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
PreDiabetes
Small Steps for Big Changes: A Lifestyle Program to Reduce the Risk of Developing Type 2 Diabetes
The purpose of this study is to address whether inactive individuals with prediabetes who take part in the Small Steps for Big Changes program, which is a 3-week supervised exercise and lifestyle change program with brief…
- Trial name
- NCT03096002
- Testing
- Lifestyle change
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of British Columbia
Diabetes, Gestational, Obesity
Maternal GDM in Hispanic Youth: Risk for Obesity
Our studies are aimed at examining effects of intrauterine exposure to GDM on metabolic risks in Hispanic children. Our primary hypothesis predicts that intrauterine exposure to GDM will be associated with one or more of three…
- Conditions
- Diabetes, Gestational, Obesity, Insulin Resistance, Insulin Secretion
- Trial name
- NCT02668601
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Diabetes Mellitus
Turkish Nationwide SurvEy of Glycemic and Other Metabolic Parameters of Patients With Diabetes Mellitus
This study evaluates the overall cardiovascular risk status and best predictors of optimal metabolic control of Turkish adult patients with diabetes mellitus.
- Trial name
- TEMD (NCT03455101)
- Testing
- There is no intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 5,240 people
- Sponsor
- Gulhane School of Medicine
Atrophy
Effect of Exercise on Risk-factors of Elderly Women
The purpose of this study is to determine whether exercise training may impact relevant risk factors and health costs of community living women older 65 years.
- Trial name
- NCT00267839
- Testing
- physical exercise, wellness
- Where
- 2 sites in Germany
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Prediabetes
Trial of an Herb and Mineral Combination Product on Fasting Glucose in Adults at Risk for Developing Diabetes
This is a multi-center, randomized, double-blind, placebo-controlled study in approximately 104 subjects (52 per group) to evaluate the effectiveness of an herb and mineral combination product on fasting serum glucose levels in…
- Trial name
- NCT02146157
- Testing
- herb and mineral combination product
- Where
- 6 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- NewChapter, Inc.
Sleep, Sleep Deprivation
Sleep Loss and Glucose Metabolism in People With Family History of Type 2 Diabetes.
The use of sugar and starch-like foods for energy (carbohydrate metabolism) changes when people sleep. However, it is still not known if differences in the amount of nighttime sleep have an effect on the carbohydrate metabolism…
- Conditions
- Sleep, Sleep Deprivation, Insulin Resistance, Type 2 Diabetes
- Trial name
- NCT00721019
- Testing
- 5-hour bedtime, 8.5-hour bedtimes
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Chicago