Clinical trials: Diabetes Mellitus Risk
Type 2 Diabetes Mellitus, Cardiovascular Risk Factor
Effectiveness of PRECEDE Model for Health Education on Changes and Level of Control in Patients With Type 2 Diabetes Mellitus
BACKGROUND: Individual health education is considered to be essential in the overall care of patients with type 2 diabetes (DM2), although there is some uncertainty regarding its metabolic control benefits.
- Trial name
- NCT01316367
- Testing
- PRECEDE HPE model, CHPE
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Hospital Carlos III, Madrid
Insulin Resistance, Insulin Resistance and Type 2 Diabetes
The Muscle Monitor: Early Skeletal Muscle Indicators of Insulin Resistance and Cardiometabolic Risk
Insulin resistance is an early etiological factor in the development of type-2 diabetes (T2D), which constitutes a large societal health burden with an expected additional rise in the years to come.
- Conditions
- Insulin Resistance, Insulin Resistance and Type 2 Diabetes, Cardiometabolic Risk Factors, Physical Activity
- Trial name
- MUSCLE MONITOR (NCT07678736)
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- University Ghent
Diabetes Mellitus, Obesity-Related Malignant Neoplasm
Eat, Move, Live Program for the Reduction of Cancer and Chronic Disease Risk in Underserved Communities
This clinical trial tests the Eat, Move, Live (EML) Program in reducing the risk of chronic diseases among underserved communities by improving healthy lifestyle practices, increasing physical activity and encouraging healthy…
- Trial name
- NCT05414396
- Testing
- Behavioral Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Diabetic Retinopathy, Retinal Neovascularization
Panretinal Photocoagulation (PRP) Plus Ranibizumab for Proliferative Diabetic Retinopathy
The purpose of this study is to evaluate the effects of panretinal photocoagulation plus intravitreal ranibizumab for the treatment of patients with high risk proliferative diabetic retinopathy in terms of changes in visual…
- Trial name
- IRaHi (NCT01102946)
- Testing
- Ranibizumab, Panretinal Photocoagulation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Diabetes Mellitus, Non Insulin Dependent Diabetes Mellitus
ED Diabetes Screening and Outpatient Care - Aim 3
This goal of this NIH funded R01 study is to identify risk factors for not being able to follow-up for a new diagnosis of diabetes in the emergency department and improve linkage of these newly diagnosed patients to appropriate…
- Trial name
- NCT05899023
- Testing
- Telehealth Bridge Visits, Standard of Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Renal Transplantation
Prediction of NODAT After Renal Transplantation
A statistical analysis of the predictive value of OGTT and FPG testing executed as part of standard clinical practice after renal transplantation for the diagosis of new-onset diabetes mellitus after transplantation.
- Trial name
- NCT00442988
- Where
- Belgium
- Volunteers
- 360 people
- Sponsor
- KU Leuven
Dyslipidemia, Angina (Stable)
Validation of Remote Photoplethysmography (rPPG)-Derived Cardiovascular Parameters Against Standard Clinical Measurements and Risk Scores in a Community
The goal of this observational study is to evaluate whether a contactless camera-based technology, called remote photoplethysmography (rPPG), can accurately measure cardiovascular parameters and estimate cardiovascular risk in…
- Conditions
- Dyslipidemia, Angina (Stable), Coronary Artery Disease (CAD), Heart Disease
- Trial name
- NCT07502703
- Where
- Indonesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Prediabetes
Time to Healthy Lifestyle Habit Using Digital Health Tools in Adults at Risk of Diabetes
1. Background \& Context The Challenge: Type 2 Diabetes (T2D) is a major public health burden. Lifestyle changes are effective, but little is known about how long it actually takes to make these changes stick.
- Trial name
- NCT07667361
- Testing
- Hybrid digital intervention with personalized support., Standard lifestyle education
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Type 2 Diabetes Mellitus, Hypertension
Blood Pressure Control for Type 2 Diabetes
The BP4DM study was initiated as a prospective randomized controlled trial to investigate the renal protection effect for tight blood pressure control for Taiwanese T2DM patients without previously diagnosed CV events.
- Trial name
- BM4DM (NCT03477786)
- Testing
- drug adjustment and behavioral modification
- Where
- 2 sites in Taiwan
- Volunteers
- 1,500 people
- Sponsor
- National Health Research Institutes, Taiwan
Diabetes, Metabolic Diseases
The Fasting II Study
This study will determine whether an intensive fasting protocol alters hemoglobin A1c measurements or other markers of metabolic and cardiovascular risk by performing a 5-week clinical trial of fasting among 12 pre-diabetic…
- Trial name
- NCT01792986
- Testing
- water-only 24-hour fasting once per week for 6 weeks
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Intermountain Health Care, Inc.
Low Density Lipoprotein Cholesterol Goal Achievement
of PATient Education Related to CV Risk factOrs in Type 2 Diabetes Mellitus(Patrol).
An observational, non-interventional, multi-centre study to provide further information on the utility of test for a predictive marker by investigating the current prevalence of high sensitivity CRP (hs-CRP) testing and…
- Trial name
- DART (NCT00925717)
- Where
- 22 sites in South Korea
- Volunteers
- 4,045 people
- Sponsor
- AstraZeneca
Cardiovascular Diseases, Cardiovascular Risk Factor
The Moli-sani Study
Cardiovascular disease and malignancies account for more than 70% of all causes of mortality and morbidity in Italy. There is a subtle balance between genetic determinants and lifestyle, that often defines the line between health…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Cancer, Neurodegenerative Diseases
- Trial name
- NCT03242109
- Where
- Italy
- Volunteers
- 24,325 people
- Sponsor
- Neuromed IRCCS
Diabetes Mellitus, Type 2, Coronary Artery Disease
Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD
The purpose of this study is to determine whether bromodomain extraterminal domain (BET) inhibition treatment with RVX000222 in high-risk type 2 diabetes mellitus patients with coronary artery disease increases the time to major…
- Trial name
- BETonMACE (NCT02586155)
- Testing
- Apabetalone, Atorvastatin, Rosuvastatin
- Where
- 214 sites in Argentina, Australia and 13 more
- Volunteers
- 2,425 people
- Sponsor
- Resverlogix Corp
Kidney Transplant, Familial Hypercholesterolaemia
Cardiovascular Risk in Children With Chronic Conditions Study
Children living with chronic health conditions face a higher risk of developing cardiovascular diseases than their peers, largely due to the accelerated aging of the heart and blood vessels.
- Conditions
- Kidney Transplant, Familial Hypercholesterolaemia, Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- CR3C (NCT07086989)
- Where
- 3 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University
Gestational Diabetes Mellitus, Dietary Habits
A Study of the Intervention of Time-restricted Eating in High-risk Populations of GDM
This is a randomized controlled trial, aiming to investigate whether a time-restricted eating (TRE) can reduce the incidence of gestational diabetes mellitus (GDM) in high-risk pregnant women.
- Conditions
- Gestational Diabetes Mellitus, Dietary Habits, Lifestyle Intervention, Randomized Controlled Study
- Trial name
- NCT06431997
- Testing
- Time-limited eating
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Fudan University
Type 2 Diabetes, Major Adverse Cardiac Events
Prediction of the SURPASS-CVOT Cardiovascular Outcome Trial in Healthcare Claims Data
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials.
- Conditions
- Type 2 Diabetes, Major Adverse Cardiac Events, Cardiovascular (CV) Risk
- Trial name
- DUP-SURPASS (NCT07088718)
- Testing
- Tirzepatide, Dulaglutide
- Where
- United States
- Volunteers
- 44,671 people
- Sponsor
- Brigham and Women's Hospital
Shift-Work Sleep Disorder
Shift Work and Risk of Cardio-vascular Disease
The purpose of this research is to test the hypothesis that those with non-traditional work schedules (e.g. shift workers) have a higher cardio-metabolic risk than those with traditional work schedules (e.g.
- Trial name
- NCT02901860
- Testing
- Sleep, Dietary and Cardio-metabolic Measurements
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Peripheral Arterial Disease
Text Messaging to Promote Walking Among Latino Adults at Risk for Peripheral Arterial Disease
The purpose of this study is to learn about the impact of text messaging on physical activity in persons with risk factors for peripheral arterial disease (PAD).
- Trial name
- NCT02622282
- Testing
- Text Messages, Phone Calls, Handout
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Type 2 Diabetes Mellitus, Bone Fractures
Microarchitecture, Bone Strength and Fracture Risk in Type 2 Diabetes
This multicenter, prospective, observational cohort study will assess bone differences in women and men with type 2 diabetes mellitus (T2DM) with and without fragility fractures.
- Trial name
- DiabOS (NCT02551315)
- Where
- 5 sites in Switzerland
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
PreDiabetes
The Lifestyle Education About Prediabetes (Leap) Study
This research tested whether a standard version or very low-carbohydrate version of the Diabetes Prevention Program better improves outcomes like blood glucose control and body weight for patients with prediabetes.
- Trial name
- LEAP (NCT05235425)
- Testing
- Standard NDPP, Very low-carbohydrate diet
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- University of Michigan
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