Clinical trials: Diabetes Mellitus Type II,
Diabetes Mellitus, Type II, Fatty Liver
Study of INT-747 in Patients With Diabetes and Presumed NAFLD
The primary objectives of this study are to assess, in patients with Type 2 diabetes mellitus (DM) and presumed nonalcoholic fatty liver disease (NAFLD), the following: The safety and tolerability of multiple doses of INT 747…
- Trial name
- NCT00501592
- Testing
- INT-747
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- Intercept Pharmaceuticals
Type 2 Diabetes Mellitus and the Effect of Sleep Hygiene Education on Sleep Quality and Glycemic Control
Sleep Hygiene Education in Type 2 Diabetes
The aim of this study is to evaluate the effect of sleep hygiene education on sleep quality and glycemic control of Type 2 Diabetes patients. Patients between the ages of 18-65, who were registered to the Gaziemir 11 No.
- Trial name
- NCT07347964
- Testing
- Sleep Hygiene Education
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dokuz Eylul University
Diabetes Mellitus, Type 2
A Study of the Pharmacokinetics/Pharmacodynamics of GK Activator (2) in Type 2 Diabetes Patients With Hepatic Impairment.
This study will investigate the effect of hepatic impairment on the pharmacokinetics, pharmacodynamics, safety and tolerability of GK Activator (2) in type 2 diabetes patients with mild and moderate hepatic impairment.
- Trial name
- NCT00437606
- Testing
- GK Activator (2), Ethanol
- Where
- 3 sites in Germany, Slovakia
- Volunteers
- 2 people
- Sponsor
- Hoffmann-La Roche
Diabetes, Type 2 Diabetes
Diabetes: Functional Medicine Approach Vs. Usual Care
A Functional Medicine (FM) approach to diabetes care focuses on identifying and treating the etiologies for "imbalances in the core physiological systems."(1) If underlying triggers and imbalances can be identified, the FM…
- Conditions
- Diabetes, Type 2 Diabetes, Type 2 Diabetes Treated with Insulin
- Trial name
- NCT03070106
- Testing
- Functional Medicine
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Keren Zhou
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Clinical Trial Investigating the Effect of Exosomes as a Complementary Treatment in Severe to Moderate Erectile Dysfunction
The goal of this clinical trial is to Investigate the Effect of Injection of MSC-Derived Exosome on Patients with Erectile Dysfunction in overall healthy males, aged 18-70, with-out any severe active medical condition, with…
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Due to Arterial Disease, Erectile Dysfunction Due to Arterial Insufficiency
- Trial name
- MSC (NCT07319533)
- Testing
- exosomes derived from human umbilical cord mesenchymal stem cells, Normal (0.9%) saline
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Labbafinejad Medical Center
Diabetes Mellitus, Type 2
Diabetes Homelessness Medication Support Program in Spanish
This single-arm trial of the Diabetes Homeless Medication Support intervention for Spanish-speaking people (n=12) will test the perception and feasibility of anticipated study procedures.
- Trial name
- DH-Spanish (NCT05819749)
- Testing
- Diabetes Homelessness Medication Support Program in Spanish
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Hennepin Healthcare Research Institute
Diabetes, Diabetes Mellitus, Type 2
Safety and Tolerability of Liraglutide in Healthy Volunteers and Subjects With Type 2 Diabetes
This trial is conducted in Europe. The aim of this trial is to assess the safety and tolerability (maximum tolerated dose) after single and multiple doses of NNC 90-1170 (liraglutide) in healthy volunteers and in subjects with…
- Conditions
- Diabetes, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT01507285
- Testing
- liraglutide
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes
Pivotal Trial of a Digital Therapeutic for the Treatment of Type 2 Diabetes
BT-001 is a software program intended to help patients with type 2 diabetes, under the guidance of their physician, improve glycemic control (i.e., levels of blood sugar).
- Trial name
- NCT04886388
- Testing
- BT-001, Physician-guided Standard of Care for type 2 diabetes
- Where
- 6 sites in United States
- Volunteers
- 668 people
- Sponsor
- Better Therapeutics
Diabetes Mellitus
Insulin Glargine Plus Insulin Glulisine Multiple Daily Injections (MDI) Versus Premix Insulin Treatment in Subjects With Diabetes Mellitus (Type 1 or Type 2)
The purpose of this study is to test for superiority in improvements from baseline in patient reported outcomes in subjects with type 1 or type 2 diabetes when treated with insulin glargine plus rapid acting insulin glulisine MDI…
- Trial name
- NCT00135941
- Testing
- insulin glargine, insulin glulisine
- Where
- United States
- Volunteers
- 582 people
- Sponsor
- Sanofi
Type 2 Diabetes, Telemedicine
Telemedicine Influence in the Follow up of the Type 2 Diabetes Patient
The purpose of this study is to evaluate the impact of a a real time teleassistance system in the clinical evolution of type 2 diabetic patients on self monitoring blood glucose in the Public National Primary Care System.
- Conditions
- Type 2 Diabetes, Telemedicine, Self Monitoring Blood Glucose, Primary Care
- Trial name
- NCT00527254
- Testing
- Telemedicine system
- Where
- Spain
- Volunteers
- 328 people
- Sponsor
- Province of Malaga Health Department
Diabetes Mellitus, Metabolic Surgery
Metabolic Surgery; Gastric Bypass vs Sleeve Gastrectomy; Efects Over Type 2 DM With Bad Metabolic Control (MSO1CT)
The aim of the study is to compare the efficacy of laparoscopic gastric bypass versus vertical gastrectomy for the resolution of DM in patients with BMI 30-35.
- Conditions
- Diabetes Mellitus, Metabolic Surgery, Sleeve Gastrectomy, BPGY
- Trial name
- MSO1CT (NCT03891056)
- Testing
- metabolic surgery
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario Doctor Peset
Type 2 Diabetes
Precision Nutrition Versus Standard Dietary Care: Continuous Glucose Monitoring as a Tool for Guided Nutrition Care in Type 2 Diabetes - The PRECISE-DIET Trial. -A Pilot Study
The primary aim of this pilot study is to assess the feasibility of a 12-week dietary intervention combined with the use of CGM in adults with T2D.
- Trial name
- NCT06832059
- Testing
- The precise diet intervention
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Steno Diabetes Center Copenhagen
Type2 Diabetes, Type 2 Diabetes Mellitus
Randomised Placebo-controlled Study of FMT to Impact Body Weight and Glycemic Control in Obese Subjects With T2DM
Faecal microbiota transplantation (FMT) represents a clinically feasible way to restore the gut microbial ecology, and has proven to be a breakthrough for the treatment of recurrent Clostridium difficile infection.
- Conditions
- Type2 Diabetes, Type 2 Diabetes Mellitus, Obese
- Trial name
- NCT03127696
- Testing
- Fecal Microbiota Transplantation, Lifestyle Modification Program
- Where
- Hong Kong
- Volunteers
- 61 people
- Sponsor
- Chinese University of Hong Kong
Diabetes Mellitus, Type 2
A Study Comparing SHR-3167 With Insulin Degludec in Adults With Type 2 Diabetes Currently Treated With Basal Insulin
The purpose of this study is to evaluate efficacy and safety of once-weekly SHR-3167 and once-daily Insulin Degludec in participants with Type 2 diabetes that has been treated with basal insulin.
- Trial name
- NCT07913061
- Testing
- SHR-3167, insulin degludec
- Where
- 2 sites in China
- Volunteers
- 680 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Diabetes Mellitus, Type 2
Pharmacodynamic Evaluation of PL2200 Versus Enteric-Coated Aspirin in Diabetic Patients
This study will determine if aspirin from PL2200, an investigational product, gets into the blood stream as quickly as enteric coated aspirin, and to test whether PL2200 is able to prevent blood clots as effectively as enteric…
- Trial name
- RITE (NCT02008942)
- Testing
- PL2200 Aspirin Capsules, Enteric-coated aspirin caplets
- Where
- 3 sites in United States
- Volunteers
- 57 people
- Sponsor
- PLx Pharma
Obesity, Type 2 Diabetes Mellitus
Impact of GBS on CVD in Type 2 Diabetes Mellitus
This research is a NIH single site study with the aims to (1) determine whether surgically induced weight loss decreases the risk of CVD in morbidly obese subjects with T2DM.
- Trial name
- NCT00787670
- Testing
- Diabetes Support and Education, gastric bypass surgery, Tissue Control Group
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Duke University
Prediabetes
Interdisciplinary and Family Intervention to Prevent Type 2 Diabetes
The purpose of the study is to evaluate the effect of a family and interdisciplinary approach on individual and family insulin resistance and insulin secretion in patients with prediabetes.
- Trial name
- CARE-in-DEEP (NCT02635646)
- Testing
- Family and interdisciplinary approach, individual approach
- Where
- Mexico
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universidad de Guanajuato
Type 2 Diabetes
Metabolic Effects of Lactobacillus Reuteri DSM 17938 in Type 2 Diabetes
Recent data suggest that the trillions of bacteria in gastrointestinal tracts (gut microbiota) can function as an environmental factor that modulates the amount of body fat.
- Trial name
- NCT01836796
- Testing
- Lactobacillus Reuteri, Lactobacillus Reuteri DSM17938
- Where
- Sweden
- Volunteers
- 46 people
- Sponsor
- Vastra Gotaland Region
Diabetes Mellitus, Non-Insulin-Dependent
A Research Study to Determine the Safety and Efficacy of Glucovance Compared to Metformin and Glyburide in Children and Adolescents With Type 2 Diabetes.
The purpose of this clinical research study is to see if Glucovance, a medication currently approved for use in adults with type 2 diabetes, can control type 2 diabetes safely and effectively in children 9 to 16 years of age.
- Trial name
- NCT00035542
- Testing
- Glucovance (metformin HCl/glyburide), metformin HCl, glyburide
- Where
- 50 sites in United States
- Sponsor
- Bristol-Myers Squibb
Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy
This study will look at the effects of CagriSema in people with both type 2 diabetes and painful diabetic peripheral neuropathy, compared to placebo.
- Trial name
- NCT06797869
- Testing
- CagriSema (Cagrilintide B and Semaglutide I)
- Where
- 55 sites in United States, Canada and 5 more
- Volunteers
- 142 people
- Sponsor
- Novo Nordisk A/S
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