Clinical trials: Diabetes Mellitus Type II,
Diabetes Mellitus, Type II, Periodontitis
Impact of Periodontal Therapy on Patients With Diabetes
With poorly controlled diabetes, periodontal status often worsens, and with severe periodontal conditions there is often poorer glycemic control.
- Trial name
- DMRCT (NCT04830969)
- Testing
- Chlorhexidine gluconate oral rinse, Scaling & Root Planing, Soft Picks
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- State University of New York at Buffalo
Diabetes Mellitus, Type 2
The Effects of LY2409021 on the Liver
This is a study that involves multiple doses of study drug (60 mg of LY2409021, 15 mg of LY2409021 or placebo) taken as capsules by mouth on a daily basis for 28 days.
- Trial name
- NCT01588366
- Testing
- LY2409021
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes
Breakfast on Postprandial Hyperglycemia
Reduction of postprandial hyperglycemia (PPHG) is a major target in the treatment of type 2 diabetes (T2D). Skipping breakfast has been consistently associated with higher HbA1c and overall PPHG in subjects with type 2 diabetes…
- Trial name
- B-PPHG (NCT02411682)
- Testing
- Breakfast eating (YesB), Breakfast skipping (NoB)
- Volunteers
- 28 people
- Sponsor
- Hospital de Clinicas Caracas
Diabetes Mellitus, Type 2, Hyperglycemia
Examining the Feasibility of Prolonged Ketone Concentrate Supplement Drink Consumption in Adults With Type 2 Diabetes
Brief Summary: Ketones are a source of energy and signaling molecule that are produced by the body when not consuming any food or consistently eating a low-carbohydrate "keto" diet.
- Conditions
- Diabetes Mellitus, Type 2, Hyperglycemia, Ketosis
- Trial name
- NCT05983562
- Testing
- Dietary Supplement: D-β-hydroxybutyric acid with R-1,3-butanediol
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Type 2 Diabetes
The Effects of Dapagliflozin in Normal Clinical Practice in T2D
The aim of the study is to evaluate the benefits, documented in experimental settings, of treatment with Dapagliflozin in subjects with type 2 diabetes in normal clinical practice.
- Trial name
- PRECARE (NCT05418946)
- Testing
- Dapagliflozin 10mg
- Where
- Italy
- Volunteers
- 1,400 people
- Sponsor
- University of Milan
Type 2 Diabetes
Type 2 Diabetes and Exercise - A Pilot Study
A randomised, cross-over trial targeting a small sample of older (age 45-65 years) overweight adults with type 2 diabetes the aims of this pilot study are to: 1.
- Trial name
- NCT00666861
- Where
- Australia
- Volunteers
- 2 people
- Sponsor
- Bayside Health
Type 2 Diabetes, Vascular Diseases
Phenotyping Individuals With Neo-diagnosed Type 2 Diabetes at Risk for All-cause Mortality
Prevalence of type 2 diabetes (T2D) is increasing worldwide over the last two decades; in these patients the rate of all-cause and cardiovascular (CV) mortality is several folds higher than in the general population, configuring…
- Conditions
- Type 2 Diabetes, Vascular Diseases, Cardiac Disease
- Trial name
- NCT04453605
- Testing
- standard treatments
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Pisa
Type 2 Diabetes, Metabolic Syndrome
Study to Evaluate the Safety and Tolerability of PBI-4050 in Type 2 Diabetes Patients With Metabolic Syndrome
This is a Phase 2, open-label, single-arm study of the safety and tolerability of PBI-4050 800 mg daily oral administration in type 2 diabetes patients with metabolic syndrome.
- Trial name
- NCT02562573
- Testing
- PBI4050
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Liminal BioSciences Ltd.
Type 2 Diabetes Mellitus
Transformation of Indigenous Primary Healthcare Delivery
Context: Indigenous peoples experience higher prevalence rates of diabetes and worse health outcomes compared to the general population because of a wide array of factors: social determinants of health, lifestyle, genetic…
- Trial name
- FORGE AHEAD (NCT02234973)
- Testing
- Quality Improvement
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Type 2 Diabetes Mellitus
Multi-Modal Intervention In Frail And Prefrail Older People With Type 2 Diabetes
The MID-Frail STUDY project focuses on the use of interventions designed to improve functional status and enhance quality of life (rather than traditional treatments such as glucose- and blood pressure- lowering) by acting on the…
- Trial name
- MID-Frail (NCT01654341)
- Testing
- Exercise, dietary and educational program
- Where
- Spain
- Volunteers
- 986 people
- Sponsor
- Hospital Universitario Getafe
Diabetes Mellitus, Type 2, Macular Edema
Effects of Adding Triamcinolone Acetonide to Conbercept Treatment for Refractory Diabetic Macular Edema (CONTE)
This study aimed to compare intravitreous conbercept alone with conbercept plus intravitreous triamcinolone acetonide in DME eyes which showed limited response to anti-VEGF treatment after one injection.
- Trial name
- CONTE (NCT04627402)
- Testing
- Conbercept and TA, Conbercept
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Diabetic Nephropathy
Evaluating The Roles of Novel Inflammatory Markers Compared to MCP-1 in Type 2 Diabetic Nephropathy
Diabetic kidney disease (DKD) is one of the most common microvascular complications of type 2 diabetes mellitus (T2DM), affecting up to 40% of diabetic patients and accounting for the leading cause of end-stage renal disease…
- Trial name
- NCT07173686
- Volunteers
- 80 people
- Sponsor
- Assiut University
Type 2 Diabetes
Social Support Intervention for Older Adults With T2DM
This study seeks to describe and evaluate the impact of social support on self-care and clinical outcomes in rural-dwelling older adults with T2DM, test the feasibility and preliminary effectiveness of a 6-week intervention…
- Trial name
- NCT04568486
- Testing
- Diabetes Empowerment Education Program
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Brittany L Smalls
Hypertension, Type 2 Diabetes Mellitus
Home Monitoring in the Management of Hypertension and Diabetes Mellitus
The home monitoring of automated measuring devices may improve the management of the chronic diseases, and may decrease the incidence of fatal disease.
- Trial name
- NCT00968786
- Testing
- Home monitoring
- Volunteers
- 100 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Diabetes Mellitus, Type 2
Thiazolidinedione Intervention With Vitamin D Evaluation
This study will answer two separate questions. The first question is to test the cardiovascular effects of long-term treatment with rosiglitazone or pioglitazone when used as part of standard of care compared to similar standard…
- Trial name
- TIDE (NCT00879970)
- Testing
- pioglitazone, rosiglitazone, Vitamin D
- Where
- 331 sites in United States, Argentina and 23 more
- Volunteers
- 1,332 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus., Chronic Periodontitis
Periodontal Treatment in Non-controlled Type 2 Diabetes Mellitus Patients. Clinical Trial
Periodontitis is an infectious disease that destroys the tooth supporting tissues and triggers a local and systemic immune response.
- Trial name
- FONIS12I2106 (NCT01904422)
- Testing
- conventional periodontal treatment
- Where
- Chile
- Volunteers
- 87 people
- Sponsor
- Universidad de los Andes, Chile
Type 2 Diabetes
Effects of Peanut and Peanut Butter Consumption on Blood Lipids and Glycemic Control in Adults With Type 2 Diabetes
Peanuts and peanut butter contain high levels of monounsaturated fat (MUFA), arginine, fiber, phytosterols, resveratrol and vitamin E that have the potential to reduce cardiovascular disease (CVD) risk through improved blood…
- Trial name
- NCT00937222
- Testing
- Peanuts and peanut butter
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Loma Linda University
Type2 Diabetes, Type 2 Diabetes Mellitus
Depression & Insulin Sensitivity in Adolescents
There has been a rise in type 2 diabetes (T2D) rates in adolescents, disproportionately in girls from disadvantaged racial/ethnic groups.
- Conditions
- Type2 Diabetes, Type 2 Diabetes Mellitus, Insulin Sensitivity, Insulin Resistance
- Trial name
- NCT03263351
- Testing
- Cognitive-behavioral therapy group, Health education group
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Colorado State University
Obesity
Effect of a Very Low-Calorie Ketogenic Diet on Gut Microbiota and Fat Distribution
Short-term interventions that use very low-calorie ketogenic diets and meal replacements may be prescribed for selected overweight or obese patients with type 2 diabetes or prediabetes.
- Trial name
- NCT04019431
- Testing
- Whey protein, vegetable protein or animal protein
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
Patient Satisfaction, Continuous Glucose Monitoring
Experience With the Use of Continuous Glucose Monitoring (CGM) Devices in People With Type 2 Diabetes Mellitus
Background: In recent years, diabetes management has evolved with the introduction of continuous glucose monitoring (CGM) devices.
- Conditions
- Patient Satisfaction, Continuous Glucose Monitoring, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- Glucocavi (NCT07019753)
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
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