Clinical trials: Diabetes Mellitus Type II,
Type 2 Diabetes Mellitus
Malaysia Diabetes Ramadan Nutrition Plan (My Dia-RNP®): A Feasibility Study
Ramadan fasting is an important event for Muslims. During Ramadan, all healthy Muslims are asked to abstain from food and drink throughout the day and eat only during daybreak (also know as Sahur in Malay/Arabic language) and…
- Trial name
- MyDia-RNP (NCT03817099)
- Testing
- Nutrition Intervention based on My Dia-RNP, Usual Care
- Where
- Malaysia
- Volunteers
- 53 people
- Sponsor
- Universiti Putra Malaysia
Diabetes Type 2, Coronary Artery Disease
Canagliflozin Targeting Vascular Inflammation
CANTOR SING is a pilot single center double blinded randomized study. The investigators will compare the effect of canagliflozin (300 mg daily - intervention arm) vs.
- Trial name
- CANTORSING (NCT05427084)
- Testing
- Canagliflozin
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Type 2 Diabetes
Comparison Study of Insulin GZR4 With Insulin Degludec
In this study, the investigational product will be compared with insulin degludec (Tresiba®) and insulin icodec (Awiqli®). The comparator products are approved for the treatment of T2DM in the European Union.
- Trial name
- NCT07146347
- Testing
- GZR4 injection
- Where
- Germany
- Volunteers
- 14 people
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Diabetes Mellitus, Type 2
Internet Diabetes Self-Management Workshop
The purpose of this study is to determine of the effectiveness of an Internet based Diabetes Self-Management workshop for people with type II diabetes.
- Trial name
- NCT00185601
- Testing
- Internet Diabetes Self-Management Program
- Where
- United States
- Volunteers
- 761 people
- Sponsor
- Stanford University
Behavior Change Interventions
Monocular-Camera-Based Mobile Exergame for Type 2 Diabetes Prevention
Exergames have demonstrated potential as effective interventions for promoting physical activity and preventing type 2 diabetes (T2D), particularly among older adults.
- Trial name
- NCT06950528
- Testing
- Control group, Kinect group, Monocular group
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Diabetes Mellitus, Type 2, Diastolic Dysfunction
Effects of Empagliflozin on Left Ventricular Diastolic Function Compared to Usual Care in Type 2 Diabetics
The purpose of the EmDia trial is to compare the effects of empagliflozin with placebo in addition to standard diabetic treatment or dietetic treatment on cardiac diastolic function in patients with type 2 Diabetes mellitus.
- Trial name
- EmDia (NCT02932436)
- Testing
- Empagliflozin
- Where
- Germany
- Volunteers
- 144 people
- Sponsor
- Johannes Gutenberg University Mainz
Type 2 Diabetes Mellitus
A Single-Dose Study of MK6349 in Patients With Type 2 Diabetes (6349-002)
A single dose study to assess the safety, tolerability, pharmacokinetics and pharmacokinetics of MK6349 in Type 2 Diabetics.
- Trial name
- NCT00943371
- Testing
- MK6349
- Volunteers
- 28 people
- Sponsor
- Merck Sharp & Dohme LLC
Type 2 Diabetes
The Pharmacokinetics Study of Single and Multiple Dose of SP2086 in Healthy Volunteers
SP2086 is a novel inhibitor of Dipeptide base peptidase 4, allows an insulin-independent approach to improve type 2 diabetes hyperglycemia.
- Trial name
- NCT02826044
- Testing
- SP2086
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Diabetes
Comparison of Insulin Glargine and NPH Insulin at Night and at Hypoglycemia in Type 2 Diabetes
Long-acting insulin injected at bedtime may cause hypoglycemia (low blood sugar) in the night in patients with diabetes. The aims of the study are 1) to compare the dynamic characteristics of long-acting insulin analog glargine…
- Trial name
- ClampHOE901 (NCT00468364)
- Testing
- insulin glargine, NPH insulin
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- University of Giessen
Type 2 Diabetes Mellitus, Diabetic Peripheral Neuropathy
Evaluation of Exenatide in Patients With Diabetic Neuropathy
This study will look at whether or not the medication exenatide improves signs and symptoms of diabetic peripheral neuropathy in people with type 2 diabetes and mild to moderate diabetic peripheral neuropathy.
- Trial name
- NCT00855439
- Testing
- Exenatide, Glargine
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Michigan
Diabetes Mellitus Type 2 in Obese, Anxiety
Influence of Probiotics in Diabetic Cardiopathies With Excessive Weight
Today in Brazil, 6.9% of the population has Diabetes Mellitus 2 (DM2). In the world, there are about 422 million people with DM2.
- Conditions
- Diabetes Mellitus Type 2 in Obese, Anxiety, Cardiopathy
- Trial name
- NCT03904901
- Testing
- Probiotics
- Where
- Brazil
- Volunteers
- 4 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Insulin Resistance
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)
Insulin promotes the clearance of sugars from the blood into skeletal muscle and fat cells for use as energy; it also promotes storage of excess nutrients as fat.
- Trial name
- DYNAMMO-T2D (NCT02697201)
- Testing
- Intralipid, Saline
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes Mellitus
Efficacy and Safety of Vildagliptin 50mg Bid as an add-on Therapy to Insulin With or Without Metformin, in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to assess the efficacy and safety of vildagliptin 50mg bid add-on therapy to improve overall glycemic control in patients with type 2 diabetes mellitus inadequately controlled on insulin with or…
- Trial name
- NCT01582230
- Testing
- Vildagliptin
- Where
- 21 sites in China, Philippines and 2 more
- Volunteers
- 293 people
- Sponsor
- Novartis Pharmaceuticals
Type 2 Diabetes, Hyperlipidemia
The Effect of Green Tea Extract on Type 2 Diabetes With Hyperlipidemia
The aim of the study is to examine whether the extract of green tea is effective on type 2 diabetes and hyperlipidemia.
- Trial name
- NCT01360567
- Testing
- Green tea extract
- Where
- 2 sites in Taiwan
- Volunteers
- 102 people
- Sponsor
- Taipei City Hospital
Diabetes Mellitus, Type 2
A Phase 2 Study of Cyclo-Z in Subjects With Type 2 Diabetes
This is a double-blind, randomized, placebo-controlled, parallel-group comparison study to evaluate the efficacy and safety of Cyclo-Z vs. placebo in adult subjects with type 2 diabetes.
- Trial name
- NCT03560271
- Testing
- Cyclo-Z
- Where
- 20 sites in United States
- Volunteers
- 256 people
- Sponsor
- NovMetaPharma Co., Ltd.
Diabetic Kidney Disease, Diabetes Mellitus, Type 2
Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy
The study is focused on the possible improving effect of N-acetylcysteine on nephropathy of type-2 diabetic patients. Study design: Prospective clinical based study.
- Conditions
- Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Diabetic Nephropathies
- Trial name
- (NAC) (NCT04531163)
- Testing
- N Acetylcysteine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Diabetic Nephropathy
Efficacy and Safety of Canagliflozin (TA-7284) in Patients With Diabetic Nephropathy
The purpose of this study is to evaluate the efficacy and safety of Canagliflozin (TA-7284) in Japanese patients with Diabetic Nephropathy, compared with placebo
- Trial name
- NCT03436693
- Testing
- Canagliflozin
- Where
- 26 sites in Japan
- Volunteers
- 308 people
- Sponsor
- Tanabe Pharma Corporation
Chronic Kidney Disease
Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease
The primary objective of this study was to demonstrate whether, in addition to standard of care, finerenone is superior to placebo in delaying the progression of kidney disease, as measured by the composite endpoint of time to…
- Trial name
- FIDELIO-DKD (NCT02540993)
- Testing
- Finerenone (BAY94-8862)
- Where
- 978 sites in United States, Argentina and 46 more
- Volunteers
- 5,734 people
- Sponsor
- Bayer
DIABETES MELLITUS, TYPE 2
Pharmaceutical Care Program for Type 2 Diabetes Mellitus
Evaluation of Pharmaceutical Care Program for Type 2 diabetes mellitus in Dhule Objectives:- 1. To evaluate Pharmaceutical care program in Type2 diabetics. 2.
- Trial name
- pcp (NCT02435693)
- Testing
- PHARMACEUTICAL CARE programe, Without PHARMACEUTICAL CARE programe
- Where
- India
- Volunteers
- 600 people
- Sponsor
- TABREJ MUJAWAR
Diabetes Mellitus, Type 2, Urosepsis
Safety of Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors Among Patients With Type 2 Diabetes
The purpose of this study is to compare the risk of serious adverse events associated with the use of sodium-glucose cotransporter 2 (SGLT2) inhibitors in comparison with the use of dipeptidyl peptidase-4 (DPP-4) inhibitors among…
- Conditions
- Diabetes Mellitus, Type 2, Urosepsis, Diabetic Ketoacidosis, Lower Extremity Amputation
- Trial name
- NCT04017221
- Testing
- Sodium-glucose cotransporter 2 (SGLT2) inhibitors, Dipeptidyl peptidase-4 (DPP-4) inhibitors, Other treatment combinations
- Where
- Canada
- Volunteers
- 1,249,636 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
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