Clinical trials: Diabetes Related Complications
Retinopathy, Diabetic
Evaluation of a Health Education Program for Type 2 Diabetes Patients
The goal of this, Retrospective and Prospective Low- Interventional study, is to implement health education interventions to promote self-care and reduce disease complications in DM Type 2 patients at higher risk of…
- Trial name
- EDUCA-DM (NCT06066021)
- Testing
- health educational sessions in diabetic patients type 2.
- Where
- Portugal
- Volunteers
- 27 people
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Diabetic Neuropathy, Painful
PDN Post Market, Multicenter, Prospective, Global Clinical Study
The purpose of this post-market study is to evaluate the real-world experience of Nevro's Spinal Cord Stimulation (SCS) therapy in patients with chronic, intractable leg pain due to painful diabetic neuropathy (PDN).
- Trial name
- PDN-PM (NCT05301816)
- Testing
- Spinal Cord Stimulator (SCS)
- Where
- 8 sites in United States
- Volunteers
- 497 people
- Sponsor
- Nevro Corp
Diabetic Polyneuropathy
Safety and Efficacy of MCC-257 in the Treatment of Diabetic Polyneuropathy
The primary objectives of the study are to evaluate the efficacy and safety of three doses of MCC-257 in patients with mild to moderate diabetic polyneuropathy
- Trial name
- NCT00307749
- Testing
- MCC-257
- Volunteers
- 420 people
- Sponsor
- Tanabe Pharma Corporation
Diabetic Macular Edema (DME)
Phase 3 Study of Intravitreal OLN324 in Adults With Diabetic Macular Edema (DME) (OLN324-CP-03)
This is a Phase 3 study of an investigational drug called OLN324, which is being developed by Ollin Biosciences as a treatment for patients with diabetic macular edema (DME).
- Trial name
- GOBI (NCT07842016)
- Testing
- OLN324, Aflibercept
- Volunteers
- 450 people
- Sponsor
- Ollin Biosciences, Inc.
Peripheral Vascular Disease, Diabetic Foot
Autologous Bone Marrow Stem Cell Transplantation for Critical, Limb-threatening Ischemia
Critical limb ischemia is a condition where the blood circulation in the limbs, in most cases the legs, is decreased so that pain and non healing wounds ensue. Mostly, this is a sequel of arteriosclerosis and/or diabetes.
- Conditions
- Peripheral Vascular Disease, Diabetic Foot, Peripheral Arterial Occlusive Disease, Leg Ulcer
- Trial name
- BONMOT (NCT00434616)
- Testing
- Autologous bone marrow cell concentrate transplantation, saline injection
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Franziskus-Krankenhaus
Diabetes Complications, Diabetic Neuropathies
Enhance Balance and Mobility in People With Type 2 Diabetic Peripheral Neuropathy
Type 2 diabetes results in a host of neuromuscular, muscular, and autonomic system impairments that accelerate age-associated limitations in functional independence and the risk of falls.
- Trial name
- DPN (NCT02541838)
- Testing
- Muscle power, balance perturbation, aerobic exercise
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- University of Maryland, Baltimore
Diabetic Retinopathy
Squalamine Lactate Eye Drops in Combination With Ranibizumab in Patients With Diabetic Macular Edema (DME)
A randomized, controlled study of the safety and efficacy of Squalamine Lactate Eye Drops in combination with Ranibizumab intravitreal injections in patients with diabetic macular edema.
- Trial name
- NCT02349516
- Testing
- Squalamine Lactate Ophthalmic Solution 0.2%
- Where
- United States
- Sponsor
- Starr Muscle
Diabetic Foot Osteomyelitis
White Blood Cell SPECT/CT and Diabetic Foot Osteomyelitis
Osteomyelitis is a risk factor for lower extremity amputation in diabetic people. Antibiotic therapy allows a remission in 60 to 80% of cases.
- Trial name
- NCT02927678
- Testing
- white blood cell SPECT/CT (Single Photon Emission Computed Tomography/Computed Tomography) imaging
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Hospices Civils de Lyon
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Diabetes Type 2, Diabetic Nephropathy
Ramipril and Clopidogrel in Oxidative Stress, Vascular Inflammation and Endothelial Dysfunction in Type 2 Diabetes and Diabetic Nephropathy
The purpose of this study is to determine whether the combination with ramipril and clopidogrel leads to further improvement of endothelial function, reduction of oxidative stress and reduction of vascular inflammation, compared…
- Conditions
- Diabetes Type 2, Diabetic Nephropathy, Vascular Disease
- Trial name
- NCT01743014
- Testing
- Ramipril, Clopidogrel
- Where
- 2 sites in Greece
- Volunteers
- 60 people
- Sponsor
- AHEPA University Hospital
Neuropathy, Diabetic, Neuropathy, Painful
Methods of Early Detection and Grading Of Diabetic Peripheral Neuropathy (MEDON)
MEDON aims to examine new methods for early detection and grading of diabetic peripheral neuropathy focusing on both small- and large nerve fibers.
- Trial name
- MEDON (NCT04078516)
- Testing
- Perception Threshold Tracking (PTT), Axon-flair mediated respons, Heart rate variability
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Acute and Chronic Wounds, Pressure Ulcers
Clinical Evaluation of the SNaP Wound Care System
The purpose of this study is to assess the efficacy of design improvements of the Spiracur SNaP Wound Care System. This study prospectively evaluates the safety and efficacy of current and new design iterations of components of…
- Conditions
- Acute and Chronic Wounds, Pressure Ulcers, Trauma Wounds, Diabetic Foot Ulcers
- Trial name
- NCT01113658
- Testing
- SNaP Wound Care System
- Where
- 2 sites in United States
- Sponsor
- 3M
Diabetic Foot Disease, Diabetic Foot Ulcer (DFU)
Implementation of a Diabetic Foot Prevention Strategy in Primary Care (iMplanta Study)
The goal of this two-arm cluster randomised controlled trial (RCT) is to evaluate the effectiveness of a new implementation strategy based on the ImM model for the Protocol of assistance to the person with diabetic foot (PAPDF)…
- Trial name
- iMplanta (NCT07004179)
- Testing
- Implementation strategy developed using the Implementation Mapping model to enhance the effective integration of the Protocol for Assistance to People with Diabetic Foot
- Where
- Spain
- Volunteers
- 1,520 people
- Sponsor
- University of the Balearic Islands
Diabesity
Hong Kong Diabesity Register & 3-Year Trial on Integrated Care for Chinese With Diabesity
People with diabetes and obesity (diabesity) are difficult to treat with many unmet needs requiring personalized treatment regimens, intensive counselling and emotional support.
- Trial name
- NCT07039279
- Testing
- Multicomponent Integrated Care Program, TourHeart + platform
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Diabetic Nephropathy, Diabetes Mellitus
Family Investigation of Nephropathy and Diabetes (F.I.N.D.)
The Family Investigation of Nephropathy and Diabetes (FIND) is a multicenter study designed to identify genetic determinants of diabetic kidney disease.
- Conditions
- Diabetic Nephropathy, Diabetes Mellitus, Diabetic Kidney Disease, Albuminuria
- Trial name
- NCT00342927
- Where
- United States
- Volunteers
- 9,084 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Foot Ulcer, Diabetic
Study to Assess the Safety of DERMASEAL for Diabetic Foot Ulcers
The goal of this clinical trial is to determine the safety of DERMASEAL for the treatment of non-healing, neuropathic diabetic foot ulcers. The main outcome measure is safety.
- Trial name
- NCT05586542
- Testing
- DERMASEAL, Plasma Film, Standard of Care
- Where
- 4 sites in United States
- Volunteers
- 26 people
- Sponsor
- Vitruvian Medical Devices, Inc.
Pregnancy Related, Obesity, Maternal
Remotely Monitored Exercise Program in Pregnant Women With Obesity
Pregnant women with obesity will be invited to participate in structured home-based exercise programme, remotely monitored
- Trial name
- GROB (NCT05331586)
- Testing
- Remote Exercise
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Diabetic Retinopathy
Pilot Study of Laser Photocoagulation Therapy for Diabetic Macular Edema
This study will compare the side effects of two laser treatments for diabetic macular edema, a common condition in patients with diabetes.
- Trial name
- NCT00069056
- Testing
- Laser Treatment
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- National Eye Institute (NEI)
Diabetic Complications and Obstructive Sleep Apnea
Diabetic Complications and Obstructive Sleep Apnea
To follow up the progress of chronic complications in T2DM patients who had undergone anthropometric measurements, laboratory testing and standard overnight polysomnography monitor from 2013 to 2018.
- Trial name
- DMOS (NCT04646941)
- Testing
- regular treatment
- Where
- China
- Volunteers
- 330 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Charcot Joint, Diabetic Foot
Characterizing and Diagnosis's of the Charcot Foot (Charcot Osteoarthropathy) in Diabetic Patients
The condition Charcot foot has been known in more than 130 years, and yet there still remains a large effort to find the cause, diagnostic and medical treatment of the condition.
- Trial name
- NCT00157222
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Bispebjerg Hospital
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