Clinical trials: Diabetes Related Complications
Obesity, Lifestyle-related Condition
Lifestyle Intervention in Preparation for Pregnancy (LIPP)
Studies evaluating lifestyle intervention in obese women during pregnancy have reported limited success in decreasing excessive gestational weight gain, and have failed to achieve the key outcome of breaking the obesity cycle and…
- Conditions
- Obesity, Lifestyle-related Condition, Macrosomia, Fetal
- Trial name
- NCT03146156
- Testing
- Lifestyle Intervention
- Where
- 4 sites in United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Diabetes, Diabetes Mellitus, Type 1
A Survey to Evaluate Diabetes Management, Control, Chronic Complications, Psychosocial Aspects of Diabetic Subjects in Indonesia
This study is conducted in Asia. The aim of this observational study is to evaluate current status of diabetes management, control, complications in diabetic subjects in Asia.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- DiabCare Asia (NCT00788853)
- Testing
- No treatment given
- Where
- Indonesia
- Volunteers
- 1,832 people
- Sponsor
- Novo Nordisk A/S
Diabetic Foot
The Effects of BAY1193397 on Skin Capillary Blood Flow and Transcutaneous Oxygen Pressure
The purpose of the study is to analyse skin blood flow in diabetic patients. The patients receive a single dose of placebo, 1 mg BAY1193397, and 5 mg BAY1193397.
- Trial name
- NCT03128320
- Testing
- BAY1193397
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Bayer
Type 2 Diabetes Mellitus With Complication
Efficacy and Safety of Bifidobacterium Quadruple Live Tablets in Patients With T2DM and Constipation
Constipation is one of the common complication of diabetes mellitus, whose pathogenesis was previously recognized as decreased gastrointestinal motility caused by diabetic autonomic neuropathy.
- Trial name
- NCT04982380
- Testing
- Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live, Siliankang simulating tablets
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Diabetes Mellitus, Ketosis, Diabetic
StatStrip Glucose/Ketone Meter System Ketone Evaluation
The Nova StatStrip Glucose / Ketone Meter System is a fast, simple, whole blood system that can be used to quantify both glucose and ketones using two distinct test strips.
- Trial name
- NCT05118061
- Testing
- Ketone
- Where
- 3 sites in United States, Germany
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Nova Biomedical
Diabetic Kidney Disease
Non Diabetic Causes of Chronic Kidney Disease in Type 2 Diabetic Patients
Determination of the possible causes of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus with an atypical presentations of renal disease for proper management and thus improving renal outcome.
- Trial name
- NCT05021705
- Volunteers
- 60 people
- Sponsor
- Assiut University
Retinal Diseases, Diabetic Retinopathy
Evaluation of Diabetic Retinopathy Using Ultra-Widefield Fundus Images Compared With Two-Field Fundus Images
This study aims to compare the accuracy of evaluating diabetic retinopathy using ultra-widefield fundus images versus two-field fundus images.
- Conditions
- Retinal Diseases, Diabetic Retinopathy, Diabetes Complications, Diabetes Mellitus
- Trial name
- NCT05836194
- Where
- China
- Volunteers
- 769 people
- Sponsor
- Ningbo Eye Hospital
Diabetic Foot Ulcer
Effects of Empowerment-based Program on Post-discharge Glycemic Control, and Foot Ulcer
The purpose of this study is to evaluate an empowerment-based program. A randomized controlled trial design will be used. From August 2019 to July 2021, 160 subjects will be recruited at a medical center and randomly assigned to…
- Trial name
- NCT03993990
- Testing
- individual empowerment-based intervention
- Where
- Taiwan
- Sponsor
- Chin yenfan
Diabetes Mellitus, Complication of Coronary Artery Bypass Graft
Relationship Between Level of Hemoglobin A1c and Platelet Function in Patients Undergoing Cardiac Surgery
The aim of this study is to evaluate whether increased level of hemoglobin A1c (HbA1c) correlates to higher level of platelet reactivity assessed by impedance aggregometry in patients with diabetes mellitus undergoing elective…
- Conditions
- Diabetes Mellitus, Complication of Coronary Artery Bypass Graft, Blood Platelet Disorders
- Trial name
- NCT02711124
- Where
- Croatia
- Volunteers
- 130 people
- Sponsor
- Clinical Hospital Centre Zagreb
Painful Diabetic Neuropathy
A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic Neuropathy
The purpose of this trial is to assess whether 400mg/day of lacosamide is effective in reducing pain caused by distal diabetic neuropathy.
- Trial name
- NCT00350103
- Testing
- SPM 929
- Where
- Germany
- Volunteers
- 551 people
- Sponsor
- UCB Pharma
Diabetic Kidney Disease (DKD)
Safety and Efficacy of the Combination Therapy of Fucoidan / Fucoxanthin / L-carnitine in Patients With Diabetic Nephropathy.
The purpose of this open-label, preliminary, proof-of-concept clinical trial is to evaluate the efficacy and safety of The purpose of this open-label, preliminary, proof-of-concept clinical trial is to evaluate the efficacy and…
- Trial name
- NCT07804641
- Testing
- Oligo-fucoidan, Fucoxanthin, L-carnitine Formula, Zinc yeast (FFL)
- Where
- Taiwan
- Volunteers
- 63 people
- Sponsor
- Taipei Medical University WanFang Hospital
Diabetic Neuropathy, Chemotherapy Induced Neuropathy
A Clinical Outcomes Study to Measure Reduction in Pain and Numbness During Administration of an Amino Acid Formulation in Subjects Diagnosed With Peripheral Neuropathy
A clinical outcomes study measuring reduction in pain and numbness experienced in four types of peripheral neuropathy patients during 60 day administration of the an amino acid formulation.
- Conditions
- Diabetic Neuropathy, Chemotherapy Induced Neuropathy, HIV Neuropathy, Trauma Induced Neuropathy
- Trial name
- Neuron012703 (NCT01537705)
- Testing
- Neuron012703 (Medical Food)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Targeted Medical Pharma
Type 2 Diabetes Mellitus (T2DM), Chronic Kidney Disease Due to Type 2 Diabetes Mellitus
Effect of Treatment With Finerenone on Cardio-Renal Target Organ Damage in Patients With Type 2 Diabetes.
The global prevalence of diabetes is increasing substantially. Around 40 % of patients with type 2 diabetes develop chronic kidney disease.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Chronic Kidney Disease Due to Type 2 Diabetes Mellitus, Cardiovascular Diseases
- Trial name
- FineCaRe (NCT07026539)
- Testing
- Finerenone (BAY 94-8862)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Eye Disease, Eye Care
Tailored Messages to Increase Eye Examination Behavior
The purpose of this project is to test two different types of health messages, one that is developed for a specific group (targeted) and the other that is more personalized to individuals (tailored), to see which is better at…
- Trial name
- NCT00649766
- Testing
- tailored newsletter, targeted newsletter
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Severe Non-proliferative Diabetic Retinopathy
Panretinal Photo-stimulation in Proliferative Diabetic Retinopathy
Diabetic retinopathy (DR) is a leading cause of new cases of blindness in people aged 20 to 65 years worldwide. Patients with DR may go on to develop a more severe form of the disease called Proliferative Diabetic Retinopathy…
- Trial name
- PRPhS (NCT02309502)
- Testing
- Green Pascal, Yellow Pascal
- Where
- United Kingdom
- Sponsor
- Manchester University NHS Foundation Trust
Cocaine Dependence
Investigation of Intranasal Oxytocin on Relapse Risk in Cocaine-dependent Patients.
This proposal describes a combined laboratory and clinical trial preliminary investigation to advance medication development for cocaine dependence.
- Trial name
- NCT02255357
- Testing
- Intranasal Oxytocin
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Type1 Diabetes Mellitus, Metabolic Complication
Cardiometabolic Risk in Children With Type 1 Diabetes.
To access the relationship between metabolic control of children and adolescents with type 1 diabetes and cardiometabolic risk through noninvasive imaging modalities to assess the early vasculature changes.
- Trial name
- NCT03544541
- Where
- Slovenia
- Volunteers
- 150 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
Diabetes
Isokinetic Strength and Balance Assessment in Diabetic Patients
Diabetic polyneuropathy (DPN) is a type of nerve damage that can occur in diabetics. It can cause weakness and a loss of sensation, particularly in the legs and feet.
- Trial name
- NCT05770154
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Diabetes, Diabetic Nephropathy
Association Between Rosiglitazone Use and Clinical Course of Diabetic Nephropathy: Population-Based Study
Recent data show that Rosiglitazone treatment can reduce proteinuria in diabetic patients. However, currently there are no trials that examine the effects of Rosiglitazone on kidney disease progression, that is, doubling of serum…
- Conditions
- Diabetes, Diabetic Nephropathy, Renal Protection
- Trial name
- NCT00497666
- Testing
- Rosiglitasone (retrospective observation)
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Diabetic Retinopathy
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
This study is open to adults with diabetic retinopathy. People who have non-proliferative diabetic retinopathy of moderate or high severity can join the study.
- Trial name
- NCT06321302
- Testing
- BI 764524, Aflibercept (Eylea®) - US only
- Where
- 90 sites in United States, Germany and 7 more
- Volunteers
- 175 people
- Sponsor
- Boehringer Ingelheim
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