Clinical trials: Diabetes Risk
Type 2 Diabetes, Chronic Kidney Diseases
Improving Screening and Therapy for Hispanic/Latinx at Risk for CKD
In Aim 1 of this study, the investigators will utilize community organizations to screen Hispanics/Latino(a)s for kidney disease, diabetes, and other risk factors, and refer them for care with a PCP.
- Trial name
- NCT05734989
- Testing
- BP, HbA1c, PCP Guidelines for Screening and Monitoring Hispanic/Latinx patients for CKD
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Duke University
Lifestyle Risk Reduction, Type2 Diabetes
Lifestyle Changes Reducing Type 2 Diabetes Risk Among Arab Canadian Muslim Women.
Aim: The purpose was to investigate whether modifiable risk factors for type 2 diabetes can be reduced by an intensive healthy lifestyle intervention designed for Arab Muslim women.
- Trial name
- NCT04708574
- Testing
- Lifestyle intervention
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Cardiovascular Disease, Diabetes Mellitus Type 2
A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities
This randomized, double-blind, placebo-controlled, parallel group, multicenter study will evaluate the potential of aleglitazar to reduce cardiovascular risk in patients with stable cardiovascular disease and glucose…
- Trial name
- NCT01715818
- Testing
- aleglitazar
- Where
- 392 sites in United States, Argentina and 25 more
- Volunteers
- 1,999 people
- Sponsor
- Hoffmann-La Roche
Type2 Diabetes, Myocardial Infarction
Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors and Risk of Cardiovascular Events
The purpose of this study is to compare the risk of cardiovascular events associated with the use of sodium-glucose cotransporter 2 (SGLT2) inhibitors in comparison with the use of dipeptidyl peptidase-4 (DPP-4) inhibitors among…
- Conditions
- Type2 Diabetes, Myocardial Infarction, Ischemic Stroke, Cardiovascular Death
- Trial name
- NCT03939624
- Testing
- Sodium-glucose cotransporter 2 (SGLT2) inhibitors, Dipeptidyl peptidase-4 (DPP-4) inhibitors
- Where
- Canada
- Volunteers
- 419,734 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
Poor Glycemic Control, Cardiovascular Risk Factors
The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health
The investigators hypothesise that carnosine supplementation will improve: 1. glycaemic control 2. cardiovascular risk factors 3.
- Conditions
- Poor Glycemic Control, Cardiovascular Risk Factors, Cognitive Function 1, Social
- Trial name
- NCT02917928
- Testing
- carnosine
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Monash University
Type 2 Diabetes, Microvascular Coronary Artery Disease
Stress Cardiac Magnetic Resonance of Asymptomatic Type 2 Diabetics with Cardiovascular High Risk to Measure Empagliflozin Impact on Myocardial Blood Flow (CATCH-EM)
The study design is a double blinded randomised control trial study that aims to conduct a randomised controlled trial of empagliflozin and determine if empagliflozin will improve myocardial blood flow in asymptomatic high risk…
- Trial name
- CATCH-EM (NCT04541797)
- Testing
- Empagliflozin 10 MG, Stress Cardiac Magnetic Resonance
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- The University of Hong Kong
Obesity, Insulin Resistance
Effects of Obesity and Intensity of Exercise on Ghrelin Levels
This study is investigating the effect of different intensities of exercise on levels of the hormone, ghrelin. In addition, we will be examining the relationship between any exercise induced changes in ghrelin and insulin…
- Conditions
- Obesity, Insulin Resistance, Cardiovascular Risk Factor
- Trial name
- NCT04581980
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Nurse's Role, Diabetes Mellitus
Nurse Coaching the Effect of on Glycemic Control, Fear of Hypoglycemia and Risk Perception in Adults With Type 1 Diabetes.
Because of the unforeseen rate of increase in case numbers, the high rates of mortality and morbidity, and the increased socio economic load it causes, diabetes has become the most discussed chronic and widespread metabolic…
- Conditions
- Nurse's Role, Diabetes Mellitus, Hypoglycemia
- Trial name
- NCT05870280
- Testing
- nurse coaching
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tuğba Bilgehan
Coronary Heart Disease, Type 2 Diabetes
Returning Genome and Metabolome Data to FinTerveys 2017 Participants: P5.fi FinTerveys Study
P5.fi study - P4 together with a fifth 'P' and '.fi' for population health Finally Implemented in Finland - studies the value of returning genetic and metabolomic risk information in two diseases (coronary heart disease and type…
- Conditions
- Coronary Heart Disease, Type 2 Diabetes, Deep Vein Thrombosis
- Trial name
- P5 (NCT03650127)
- Where
- Finland
- Volunteers
- 3,449 people, healthy volunteers welcome
- Sponsor
- Markus Perola
Obesity, Prediabetic State
Lifestyle-Related Health Outcomes in Prediabetes and Diabetes
This study looks as how a health education intervention strategy effects health outcomes in overweight and obese adolescents.
- Conditions
- Obesity, Prediabetic State, Type 2 Diabetes
- Trial name
- NCT02535169
- Testing
- Health Education and Coaching Strategy, Dietary consult
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Indiana University
Glucose Metabolism Disorders
Impairment in Glucose Homeostasis Among Obese Adolescents in High Risk Diabetes Prone Population - Jisr Az-Zarqa Village
Obesity is increasing all over the world in adults, adolescents and children,and is followed by morbidity, including the metabolic syndrome.
- Trial name
- NCT01535105
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Meir Medical Center
Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR
New Taipei City 888 Digital Medical AI Platform for Prevention and Care of the Three Highs and Cardio-Renal-Vascular Diseases
Non-communicable diseases (NCDs), or chronic diseases, are a major public health burden globally and in Taiwan, and control of the "three highs" (hypertension, dyslipidemia, and hyperglycemia) is a national priority.
- Conditions
- Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR, Cardiovascular Disease Risk Factor, Cardiovascular Disease Prevention
- Trial name
- DIGICARE-DREAM (NCT07588256)
- Testing
- Interactive digital modules, Antihypertensive Medication Management
- Where
- Taiwan
- Volunteers
- 4,162 people
- Sponsor
- New Taipei City Medical Association
Type 2 Diabetes Mellitus, Mild Cognitive Impairment
Risk Model of Cognitive Impairment in Diabetes
Development and validation of a risk model for predicting the risk of mild cognitive impairment among individuals of type 2 diabetes.
- Trial name
- NCT05590442
- Testing
- Tests
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Diabetic Retinopathy, Retinal Neovascularization
Panretinal Photocoagulation (PRP) Plus Ranibizumab for Proliferative Diabetic Retinopathy
The purpose of this study is to evaluate the effects of panretinal photocoagulation plus intravitreal ranibizumab for the treatment of patients with high risk proliferative diabetic retinopathy in terms of changes in visual…
- Trial name
- IRaHi (NCT01102946)
- Testing
- Ranibizumab, Panretinal Photocoagulation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Diabetes Mellitus, Cardiovascular Diseases
The Risk Factors of Cardiovascular Disease in Elderly Diabetic Patients: A Prospective Cohort Study
In the previous cohort studies focused on diabetes in China, there were few studies on elderly patients with diabetes. The aim of this prospective cohort study was to investigate the prevalence, management and nutritional status…
- Conditions
- Diabetes Mellitus, Cardiovascular Diseases, Complication Diabetic
- Trial name
- NCT04544527
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Sedentary Lifestyle
The Health Action Process Approach and Movement Patterns in Adult Office Workers
Societal changes have resulted in reduced demands to be active and increased daily time spent sitting. Excessive sitting has been shown to be a health hazard.
- Trial name
- NCT03091686
- Testing
- HAPA SB Intervention Slideshow, HAPA MVPA Attention-Control Slideshow
- Where
- Canada
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
PreDiabetes
Effect of the SCL16A11 Risk Haplotype on Treatments to Prevent Type 2 Diabetes
The goal of this randomized clinical trial is to determine the impact of the risk haplotype on SLC16A11 on early therapeutic responses in treatments to prevent T2D in Mexican mestizos with prediabetes.
- Trial name
- PRED2 (NCT05990205)
- Testing
- Life Style Intervention + Metformin, Life Style Intervention
- Where
- Mexico
- Volunteers
- 437 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Diabetes Mellitus, Type 2, Genetics
Phenotyping Genetic Risk for Type 2 Diabetes
This study tests the hypothesis that non-diabetic individuals with a high genetic risk score for type 2 diabetes have impaired glucose tolerance and insulin resistance compared to those with a low genetic risk score for type 2…
- Trial name
- NCT04024631
- Testing
- 75g glucose beverage (Glucola, Trutol, or similar brand), DXA, whole body
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Type 2 Diabetes, Cardiovascular Disease
Effect of Nuts vs. a Wheat Bran Muffin in Type 2 Diabetes
To determine if tree nuts (Almonds, Hazelnuts, Pistachios, Peanuts, Macadamia nuts, Pecans, Walnuts and Cashews) improve glycemic control in type 2 diabetes, as assessed by HbA1c and serum fructosamine, and to assess whether…
- Conditions
- Type 2 Diabetes, Cardiovascular Disease, Diet Therapy
- Trial name
- NCT00410722
- Testing
- Whole wheat and bran muffin, Mixed tree nuts
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Toronto
Type 2 Diabetes, High Blood Pressure
Polypill for Prevention of Cardiomyopathy
This study will investigate the utility of a polypill-based strategy for patients with type 2 diabetes mellitus and high risk of heart failure (HF), as assessed via the WATCH-DM risk score.
- Trial name
- PolyPreventHF (NCT06143566)
- Testing
- Polypill, Combined prescription of the individual medications
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center