Clinical trials: Diabetes Type I
Diabetes, Diabetes Mellitus, Type 1
A Survey to Evaluate Diabetes Management, Control, Chronic Complications, Psychosocial Aspects of Diabetic Subjects in India
This study is conducted in Asia. The aim of this observational study is to evaluate the current status of diabetes management, control, and complications in diabetic subjects in India.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- DiabCare India (NCT01351922)
- Testing
- No treatment given
- Where
- India
- Volunteers
- 12,000 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus
Calibration of a Non-invasive Glucose Measurement Device and Assessment of Its Performance in the Hypoglycemic Range in Patients With Type 1 Diabetes
This clinical study has been launched to collect spectral Raman data and reference measurements to establish and validate a calibration model for the device during daily glycemic fluctuations and evaluate analytical performance…
- Trial name
- NCT04126759
- Testing
- P0.3
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- RSP Systems A/S
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy
Penile Implant Intraoperative Measurements Planning Chart
This is a chart of penile size measurements where penile length and width are recorded intra-operatively prior to penile prosthesis implantation to guide the surgeon to the correct and adequate post-operative penile size
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction With Diabetes Mellitus, Erectile Dysfunction Due to Arterial Disease
- Trial name
- PIIMP (NCT05531877)
- Testing
- Penile Prosthesis Implantation
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Diabetes Mellitus, Type 1
Reversing Type 1 Diabetes After it is Established
The primary purpose of this study is to determine if giving the combination therapy consisting of Thymoglobulin® (ATG) and Neulasta® (GCSF) to patients with established Type 1 Diabetes (T1D) is safe and secondarily, if the ATG…
- Trial name
- NCT01106157
- Testing
- Anti-Thymocyte Globin (ATG), Pegylated GCSF
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Diabetes Mellitus, Type 1
Participant-Reported Outcomes With the Accu-Chek® Solo Micropump System
This interventional device study aims to compare mainly standard Multiple Daily Injection (MDI) therapy vs. Accu-Chek® Solo Micropump System and investigates participant satisfaction.
- Trial name
- PRO Solo (NCT03478969)
- Testing
- Accu-Chek® Solo micropump system, mylife™ OmniPod® Insulin Management System, Multiple Daily Injections (MDI) therapy
- Where
- 21 sites in Austria, Germany and 2 more
- Volunteers
- 181 people
- Sponsor
- Hoffmann-La Roche
Peripheral Neuropathy
Evaluation of Nerve Ultrasound in Detecting Clinical and Subclinical Peripheral Neuropathy in Children and Adolescents With Type 1 Diabetes Mellitus
Aim of study: To evaluate accuracy of nerve ultrasound in detecting clinical and subclinical peripheral neuropathy in children and adolescents diagnosed with type 1 diabetes melitus .
- Trial name
- NCT06187129
- Testing
- nerve ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Esraa Hosny Dahy
Type 1 Diabetes Mellitus
Assessment of an Alternative Model of Follow-up of Children and Adolescents With Type 1 Diabetes
The purpose of the study is to look at the effect of replacing the physician only visit by a transmission of information on the participant's current diabetes management and blood glucose monitoring results followed by a phone…
- Trial name
- NCT00521105
- Testing
- Virtual visit
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- University of Calgary
Type1diabetes
Root Cause Determination of Catheter Obstructions
During this study, the investigators will perform a collection of biological and device samples (blood, catheters, insulin) in order to investigate the causes of catheter obstructions in patients with type 1 diabetes treated by…
- Trial name
- CATS (NCT03230266)
- Testing
- Collection of intra-peritoneal catheters for insulin infusion
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Montpellier
Type 1 Diabetes, Cardiovascular Risk Factor
Determinants of Cardiovascular Disease Risk Factors Among Youth With Type 1 Diabetes
Type 1 diabetes mellitus (T1D) is the most common form of diabetes among children and youth, and it is increasing around the world, particularly among children under 5 years.
- Trial name
- CARDEA (NCT04304729)
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Type 1 Diabetes Mellitus
Adaptive Biobehavioral Control (ABC) of Automated Insulin Delivery
The purpose of this pilot study is to test the safety and feasibility of using two or three research modules in conjunction with an automated insulin delivery device (AID).
- Trial name
- NCT04784637
- Testing
- Web Simulation Tool (WST), Behavioral Adaptation Module (BAM), Auto Titration Module (ATM)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Virginia
Periodontitis, Type 2 Diabetes
Salivary C1P and PGE2 Levels in Periodontitis Patients With T2DM and Effect of Non-Surgical Periodontal Treatment
Diabetes and periodontal disease are the most common chronic multifactorial and inflammatory diseases in humans, and there is a bidirectional relationship between type 2 diabetes and periodontitis.
- Trial name
- NCT05454059
- Testing
- Non-surgical periodontal treatment, ELISA Test, Periodontal Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Diabetes Mellitus, Type 1, Epilepsy
Impact of Parental Perfectionistic Cognitions Self-compassion Intervention Effects on Shame in Child Health Context
Parents of children with long-term health conditions (LTCs) can experience shame related to parenting. Whilst self-compassion interventions (SCIs) can reduce parental shame, this has not been studied with parents of children with…
- Conditions
- Diabetes Mellitus, Type 1, Epilepsy, Asthma, Shame
- Trial name
- NCT03504605
- Testing
- Online self-compassion intervention
- Where
- United Kingdom
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Type1 Diabetes Mellitus
FreeStyle Libre Plus Bluetooth Transmitter Adjunct: Can This Improve Glucose Accuracy and Reduce Burden of Hypoglycaemia
Advanced glucose monitoring systems have revolutionized diabetes care and enabled people with diabetes to achieve better diabetes control with reduced risk of hypoglycaemia.
- Trial name
- FSL-M (NCT04147637)
- Testing
- FreeStyle Libre with MiaoMiao, FreeStyle Libre alone
- Where
- Kuwait
- Sponsor
- Dasman Diabetes Institute
Diabetes Mellitus, Diabetes Mellitus, Type 1
Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study
The goal of this observational study is to evaluate the predictive value of the genetic risk score for type 1 diabetes in the progression to insulin deficiency in diabetic patients. The main question it aims to answer is: 1.
- Trial name
- NCT07621445
- Where
- China
- Volunteers
- 2,950 people
- Sponsor
- Second Xiangya Hospital of Central South University
Type 1 Diabetes, Type 1 Diabetes (Juvenile Onset)
R-5280 in Newly Diagnosed Patients With Type 1 Diabetes
Evaluating the adverse events and tolerance of R-5280 in Mitigating Type 1 Diabetes in Newly Diagnosed Patients
- Conditions
- Type 1 Diabetes, Type 1 Diabetes (Juvenile Onset), Diabetes Mellitus, Type 1
- Trial name
- R-5280 (NCT06057454)
- Testing
- R-5280
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Rise Therapeutics LLC
Advanced Hepatocellular Carcinoma
A Study of Cadonilimab Combined With Regorafenib in Patients With Advanced HCC
To evaluate the efficacy and safety of cadonilimab combined with regorafenib in patients with HCC who progressed on systemic therapy.
- Trial name
- NCT05773105
- Testing
- Cadonilimab+regorafenib
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Sun Yat-sen University
T1DM - Type 1 Diabetes Mellitus
Allogeneic Anti-CD7 CAR-T for Type 1 Diabetes
Type 1 diabetes mellitus (T1DM) is a T cell-mediated autoimmune disease characterized by autoimmune destruction of pancreatic beta cells, leading to absolute insulin deficiency and lifelong dependence on exogenous insulin.
- Trial name
- NCT07528105
- Testing
- Allogeneic CD7-Targeted CAR-T Cell Injection
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Shanghai Zhongshan Hospital
Diabetes, Diabetes Mellitus, Type 1
Liraglutide as add-on to Insulin in Type 1 Diabetes
The purpose of this study is to: Part 1: To investigate how 12 weeks treatment with liraglutide affects glycemic control in poorly controlled patients and how the treatment affects gastric emptying rate during hypoglycemia.
- Trial name
- T1DMLIRA (NCT02092896)
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Hvidovre University Hospital
Diabetes Mellitus, Type 1
Anti-viral Action Against Type 1 Diabetes Autoimmunity
The study GPPAD-05 AVAnT1A is a phase 4 clinical trial intending to enroll 2252 children, who will be randomly assigned to receive COVID-19 vaccination (Comirnaty® 3 μg Omicron XBB.1.5 or new variant Comirnaty vaccines ) or…
- Trial name
- NCT06452654
- Testing
- Comirnaty Injectable Product, Sodium Chloride 0.9% Inj
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 2,252 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Type 1 Diabetes
Group Visits for High Risk Type 1 Diabetes (T1D)
The investigators propose to conduct a pilot prospective cohort study to assess the impact of shared medical appointments (SMA) visits in underserved youth with poorly controlled type 1 diabetes (T1D).
- Trial name
- NCT05431686
- Testing
- SMA visits
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Children's National Research Institute
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