Clinical trials: Diabetes in Adolescence
Type 1 Diabetes Mellitus
Optimizing Adherence and Glycemia in Youth With New Insulin-dependent Diabetes Mellitus (IDDM)
This 2-year randomized, controlled trial examined the impact of a clinic-based, family teamwork intervention on glycemic control in youth with recently diagnosed type 1 diabetes.
- Trial name
- NCT00745342
- Testing
- Family Teamwork Intervention
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Joslin Diabetes Center
Overweight and Obesity, PreDiabetes
Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation
The purpose of this research study is to determine whether continuous glucose monitors (CGM) are a safe, effective, and acceptable way to evaluate type 2 diabetes risk in youth as compared to the standard 2-hour oral glucose…
- Conditions
- Overweight and Obesity, PreDiabetes, Insulin Resistance
- Trial name
- NCT05404711
- Testing
- CGM
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mary Ellen Vajravelu, MD
Diabetes, Diabetes Mellitus, Type 1
A Trial Investigating the Pharmacokinetic Properties of FIAsp in Children, Adolescents and Adults With Type 1 Diabetes
This trial is conducted in Europe. The aim of the trial is to investigate the pharmacokinetic (the exposure of the trial drug in the body) properties of FIAsp (faster-acting insulin aspart) in children, adolescents and adults…
- Trial name
- NCT02035371
- Testing
- Faster-acting insulin aspart, insulin aspart
- Where
- Germany
- Volunteers
- 41 people
- Sponsor
- Novo Nordisk A/S
Pre Diabetes
Diabetes Prevention Program in Youth
The purpose of this study is to test the effectiveness of an out-of-school diabetes prevention program for youth (ages 7-15) with a family history of pre-diabetes or type 2 diabetes.
- Trial name
- NCT03042936
- Testing
- Insulin Superheroes Club Curriculum
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Type 1 Diabetes, HbA1c
Steno Diabetes Dialogue Cards Teaching on Group Education on Blood Sugar Control in Adolescents With Type 1 Diabetes
The Type 1 diabetes is the autoimmunity system produces the antibody which starts to attack the B lymphocytes while the autoimmunity is also been attacked.
- Conditions
- Type 1 Diabetes, HbA1c, Self-management
- Trial name
- NCT05394532
- Testing
- Education
- Where
- Taiwan
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Pediatric Obesity
Family Focused Community Program to Prevent Type 2 Diabetes in Peripubertal Youth
Over one-third of children and adolescents are overweight and nearly 1 in 5 of them are obese. Metabolic syndrome, a strong predictor of Type 2 diabetes (T2D) and cardiovascular disease (CVD), occurs in up to 44% of obese youth…
- Trial name
- NCT02421198
- Testing
- YMCA Family Diabetes Prevention Program (YFDPP)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Prediabetes
Effect of Increased Physical Activity and Stopping Evening Snacking in Metabolic Health in Youth With Prediabetes
Non-healthy eating habits and a lack of exercise contribute to prediabetes and type 2 diabetes (T2D). Evening snacking is linked to abnormal weight gain in adults and healthy adolescents.
- Trial name
- NCT06782906
- Testing
- ≥10,000 daily steps (≥5 days/week) and stopping evening snacking
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Diabetes Mellitus
Adjunctive Metformin Therapy in Double Diabetes
The significance of this project is to investigate the effects of adjunctive metformin therapy in children and adolescents with double diabetes.
- Trial name
- AMTIDD (NCT01334125)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Massachusetts, Worcester
Obesity, Type 2 Diabetes
Reducing Obesity and Type 2 Diabetes in High Risk Youth
Compare the effect of the HEALT[e]TEEN program and a HEALTH[e]TEEN plus coping skills training delivered to high school students on BMI, nutrition and physical activity behaviors, and self-efficacy over 6 months.
- Trial name
- HEALTH[e]TEEN (NCT01560676)
- Testing
- HEALTH[e]TEEN, HEALTH[e]TEEN + CST
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Yale University
Type 1 Diabetes
Social Media Use in Adolescent Diabetes Care
The goal of this clinical trial is to evaluate the feasibility of a social media intervention to support diabetes management in adolescents with type 1 diabetes.
- Trial name
- NCT06085339
- Testing
- Social Media
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Type 1 Diabetes
Turkish Validity and Reliability Study of Diabetes-Specific Nutrition Knowledge Questionnaire in Adolescents With Type 1 Diabetes
It is aimed to contribute to the Turkish Nutrition Sciences literature and shed light on the studies of future generations by establishing the Turkish validity and reliability of this scale, which was developed for adolescents…
- Trial name
- NCT07232381
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Yasemin Atik Altinok
Menstrual Irregularities, Type1 Diabetes Mellitus
Role of Glucagon-like Peptide-1 Receptor Agonists in Menstrual Irregularities in Adolescent Females With Type 1 Diabetes Mellitus
The aim of this study is to measure the frequency of menstrual irregularities among adolescent females with Type 1 diabetes mellitus and to assess the therapeutic effect of glucagon-like peptide-1 receptor agonist on menstrual…
- Conditions
- Menstrual Irregularities, Type1 Diabetes Mellitus, Glucagon-Like Peptide-1 Receptor Agonists, Female Reproductive Health
- Trial name
- NCT07319286
- Testing
- Dulaglutide
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Diabetes Mellitus Type 2, Childhood-Onset
DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
The goal of the DISCOVERY study is to provide innovative critical information regarding the unique natural history of glycemic control, insulin sensitivity, and β-cell function, and their mechanistic determinates, in obese…
- Trial name
- DISCOVERY (NCT06525259)
- Where
- 20 sites in United States
- Volunteers
- 3,600 people
- Sponsor
- George Washington University
Diabetes Mellitus, Type 2
Prevention of Type 2 Diabetes Mellitus in Children
This is a pilot study to examine the short-term effects of supervised exercise on metabolic risk factors for type 2 diabetes mellitus in children from a population that is at high risk for this disease.
- Trial name
- NCT00073268
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 1 Diabetes
Achieving Health in Emerging Adults With Diabetes (AHEAD) Program: A Clinical Trial Designed to Understand if Participation in a Clinical Program Developed Specifically to Support Emerging Adults With Type 1 Diabetes Leads to Improved Diabetes Outcomes.
The goal of this study is to determine whether the Achieving Health in Emerging Adults with Diabetes (AHEAD) Program helps emerging adults with type 1 diabetes improve their blood glucose management during the transition from…
- Trial name
- AHEAD Program (NCT07292558)
- Testing
- AHEAD Program
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- University of British Columbia
Type 1 Diabetes Mellitus
Impact of ELKa, the Toolset for Food Exchanges Calculation on Metabolic Control in Pediatric Diabetic Patients.
ELKa system is an advanced toolset which helps performing calculation of carbohydrate (CHO) and fat/protein (FP) exchanges. It consists of ELKa software including database of various meals and nutrients and ELKaPlus digital…
- Trial name
- NCT02194517
- Testing
- ELKa
- Where
- Poland
- Volunteers
- 106 people
- Sponsor
- Medical University of Warsaw
Type 1 Diabetes, Cardiovascular Risk Factor
Determinants of Cardiovascular Disease Risk Factors Among Youth With Type 1 Diabetes
Type 1 diabetes mellitus (T1D) is the most common form of diabetes among children and youth, and it is increasing around the world, particularly among children under 5 years.
- Trial name
- CARDEA (NCT04304729)
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Type 1 Diabetes, Type1diabetes
Probiotics in Newly Diagnosed T1D
The investigators aim to further the understanding of environmental factors that underlie the development of Type 1 diabetes (T1D) and the post-onset disease trajectory.
- Conditions
- Type 1 Diabetes, Type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT04141761
- Testing
- Visbiome
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Medical College of Wisconsin
type1diabetes
Motivational Interviewing to Improve Self Management in Youth With Type 1 Diabetes
A brief, nurse-led educational intervention using motivational interviewing substantially improved general and disease-specific self-management skills in youth with type 1 diabetes.
- Trial name
- NCT04798937
- Testing
- Motivational interviewing
- Where
- Tunisia
- Volunteers
- 66 people
- Sponsor
- Université de Sousse
Young Onset Asian Diabetes (Under 40 Years)
Diabetes In Asians at Risk in Youth
This observational study aims to develop novel contemporary risk factor tools for detecting young onset diabetes (under 40y) in young Asians in Singapore.
- Trial name
- DIARY (NCT07452159)
- Testing
- Oral glucose tolerance test and HbA1c, Anthropometric measurements, Body impedance Analysis
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital