Clinical trials: Diabetes in Adolescence
Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy
Prevalence of Peripheral Neuropathy in Children and Adolescents With Type I Diabetes Mellitus: a Prospective Study
Diabetes mellitus type I is an increasing burden for more and younger children. Therapy should avoid long-term complications as macrovascular diseases and diabetic nephropathy, retinopathy and diabetic neuropathy (DN).
- Conditions
- Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy, Nerve Conduction Study Not Performed
- Trial name
- NCT01512030
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Landeskrankenhaus Feldkirch
Diabetes in Adolescence, PreDiabetes
The Efficacy of AP029 Mix in Patients With Impaired Carbohydrate Metabolism
The aim of the study is to demonstrate that a daily supplementation of AP029 Mix: I) has a positive effect on reducing side effects of metformin, while enhancing the therapeutic effect of metformin; II) normalizes prediabetes…
- Trial name
- NCT05994586
- Testing
- AP029 mix
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- AronPharma Sp. z o. o.
Type 1 Diabetes (T1D)
Pragmatic Clinic-Based Trial of a Mindfulness Based Intervention for Mood Concerns in Youth With Type 1 Diabetes
Type 1 diabetes (T1D) is a common chronic illness among children requiring a high degree of self-management for good glycemic control.
- Trial name
- BREATHE-T1D (NCT06618027)
- Testing
- BREATHE-T1D, HealthEd-T1D
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Children's National Research Institute
Adolescent Girls, Diabete Mellitus
Menses&Change in Diabetic Girl
To assess menstraul cycle changes in adolescent girls with diabetes and to find out the various risk factors
- Trial name
- NCT07194291
- Testing
- Follow up of female sexual function
- Volunteers
- 110 people
- Sponsor
- Assiut University
Type 1 Diabetes Mellitus
A Qualitative Study on CSII in Children and Adolescents Having Type 1 Diabetes
Using qualitative method; a qualitative case study using semi-structured interviews to explore patients' experiences. Study population of insulin pump patients aged 11-18 years old will be recruited from pediatrics with T1D at…
- Trial name
- NCT03066284
- Where
- Kuwait
- Volunteers
- 20 people
- Sponsor
- Dasman Diabetes Institute
Impaired Glucose Tolerance, Pre-diabetes
Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth
The purpose of the study is to determine the role of beta-cell function and insulin resistance in the development of impaired glucose tolerance (IGT) and type 2 diabetes in children and adolescents who have an increased risk of…
- Conditions
- Impaired Glucose Tolerance, Pre-diabetes, Childhood Obesity, Insulin Resistance
- Trial name
- NCT00536250
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Yale University
Type 1 Diabetes, Motivational Interviewing
The Impact of Motivational Interviews Conducted Through Tele-Nursing on Diabetes Management
The deterioration of glycemic control in adolescents with Type 1 diabetes (T1DM) is a genuine cause for concern. Possible reasons for worsening glycemic control in youth include lack of monitoring, inadequate self-care…
- Trial name
- NCT06208618
- Testing
- Education and Motivational Interviews
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Eskisehir Osmangazi University
Diabetes, Diabetes Mellitus, Type 1
Efficacy and Safety of Faster-acting Insulin Aspart Compared to NovoRapid® Both in Combination With Insulin Degludec in Children and Adolescents With Type 1 Diabetes
This trial is conducted globally. The aim of the trial is to investigate efficacy and safety of faster-acting insulin aspart compared to NovoRapid® both in combination with insulin degludec in children and adolescents with type 1…
- Trial name
- onset®7 (NCT02670915)
- Testing
- Faster-acting insulin aspart, insulin aspart, insulin degludec
- Where
- 155 sites in United States, Bulgaria and 16 more
- Volunteers
- 834 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes
Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes…
- Trial name
- NCT05892848
- Testing
- serum ostecalcin,serum sclerostin and parathroid profile
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Obesity and Diabetes Mellitus, Type 2, Diabetes Prevention
PATHS-UP Health Behavior Self-monitoring Mobile App for Adolescents
Hispanic adolescents in the U.S. are disproportionately burdened by type 2 diabetes (T2D) compared to non-Hispanic white youth (0.079% vs.
- Trial name
- PATHS-UP (NCT06959901)
- Testing
- PATHS-UP Mobile Phone Application
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
Pediatric Atorvastatin in Diabetes Intervention Trial (PADIT)
The purpose of this study is to determine if Atorvastatin can improve blood vessel stiffness and blood vessel function in children 10-18 years old with Type 1 and Type 2 diabetes.
- Trial name
- NCT00130481
- Testing
- Atorvastatin 20 mg daily for 3 months
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Type 1 Diabetes Mellitus
Strategies to Enhance New CGM Use in Early Childhood (SENCE)
The primary objective of this study is to compare the efficacy and safety of CGM alone and CGM combined with a family behavioral intervention with a control group using home blood glucose monitoring (BGM) alone.
- Trial name
- SENCE (NCT02912728)
- Testing
- CGM + Family Behavioral Intervention, Standard CGM
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Jaeb Center for Health Research
Type 1 Diabetes
Anti-diabetic Effects of Liraglutide in Adolescents and Young Subjects With Type 1 Diabetes
This is the first prospective randomized double-blind placebo-controlled study to investigate the effect of a GLP-1 analog, specifically liraglutide, on blood glucose levels and variability in subjects with type 1 diabetes…
- Trial name
- NCT01722227
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University at Buffalo
Type 1 Diabetes Mellitus
Transdisciplinary Versus Usual Care for Type1 Diabetes in Adolescence
This study will consist of a randomized controlled trial to test a novel Transdisciplinary Care (TC) model of delivery of care for type 1 diabetes in adolescence.
- Trial name
- NCT03557151
- Testing
- Usual Care, Transdisciplinary Care-In Person & Telehealth
- Where
- 3 sites in United States
- Volunteers
- 230 people
- Sponsor
- Nemours Children's Clinic
Atherosclerotic Cardiovascular Disease, Childhood Diabetes Mellitus
Atherosclerotic Cardiovascular Risk in Childhood and Teen-age Onset Diabetes
For children and adolescents with diabetes, the pathological process of atherosclerotic cardiovascular disease(ASCVD) can exist in early childhood and progress rapidly to subclinical ASCVD.
- Conditions
- Atherosclerotic Cardiovascular Disease, Childhood Diabetes Mellitus, Juvenile Diabetes
- Trial name
- NCT05294653
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Type 1 Diabetes
Children's Mercy Teens With Type 1 Diabetes Will Participate in an Online Peer Support Group.
The goal of this observational study is to examine the impact of an online peer support group in Children's Mercy teens with Type 1 Diabetes.
- Trial name
- NCT06412146
- Testing
- Peer Support Group
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Pediatric Obesity, Prediabetic State
Health Outcomes of Teens Participating in Summer Employment Immersion Programs
This study is a collaboration between investigators and two community partners: a youth employment program and an urban farm. The community partners hire 300+ adolescents for summer jobs at various organizations.
- Trial name
- NCT02886208
- Testing
- Measurement
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Indiana University
Sickle Cell Disease, Chronic Kidney Diseases
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions
The purpose of this study is to test the efficacy of a peer support coaching intervention to improve activated chronic illness self-management versus an attention control group in 225 adolescents and young adults with childhood…
- Conditions
- Sickle Cell Disease, Chronic Kidney Diseases, Systemic Lupus Erythematosus, Childhood Cancer
- Trial name
- PiCASO (NCT03938324)
- Testing
- PiCASO Intervention Group
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Duke University
Type 1 Diabetes Mellitus
Frexalimab in Preservation of Endogenous Insulin Secretion Compared to Placebo in Adults and Adolescents on Top of Insulin Therapy (FABULINUS)
This is a randomized, parallel group, double-blind Phase 2 study with a blinded extension evaluating the safety and efficacy of 3 dose levels of frexalimab in comparison with placebo in participants with newly diagnosed T1D on…
- Trial name
- FABULINUS (NCT06111586)
- Testing
- Frexalimab, Insulin
- Where
- 79 sites in United States, Austria and 14 more
- Volunteers
- 197 people
- Sponsor
- Sanofi
Type 1 Diabetes
InvesT1D: Promoting Adolescent Investment in Diabetes Care
The goal of this clinical trial is to see if a financial incentives program called InvesT1D is helpful to support diabetes management in adolescents with type 1 diabetes.
- Trial name
- NCT06384911
- Testing
- Financial Incentives Program
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Harvard Pilgrim Health Care