Clinical trials: Diabetes in Pregnancy
Attention Deficit Disorder With Hyperactivity, Asthma
Study of an Intervention to Improve Problem List Accuracy and Use
The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Asthma, COPD, Breast Cancer
- Trial name
- MAPLE (NCT01105923)
- Testing
- MAPLE
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Brigham and Women's Hospital
Gestational Diabetes Mellitus (GDM), Microbiome, Human
A Probiotic Based Intervention in Pregnancies Complicated by GDM
This study is a single center randomized control trial of a probiotic based intervention in pregnancies complicated by gestational diabetes.
- Trial name
- ProbioGDM (NCT06794723)
- Testing
- 5-strain probiotic plus prebiotic natural health product
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- Queen's University
Gestational Diabetes Mellitus in Pregnancy
Afamin in Gestational Diabetes Mellitus
This study includes pregnancies in 11 to 14 th gestational weeks. Investigators will sample maternal plasma in the first trimester and analyze maternal plasma afamin values. All these women will then be screened by two step OGTT.
- Trial name
- NCT04054843
- Testing
- Afamin
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Heart Failure With Preserved Ejection Fraction (HFPEF)
Association of Heterogeneous Circulating Biomarkers and Anamnestic Factors of Pregnancy Adverse Course and Outcomes With the Prognosis of Heart Failure With Preserved Ejection Fraction
The primary purpose of this study is to evaluate possible association of some heterogeneous circulating biomarkers and anamnestic factors of pregnancy adverse course and outcomes with the prognosis of heart failure with preserved…
- Trial name
- CARPO-HF (NCT06803849)
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Urologic Diseases, Erectile Dysfunction With Diabetes Mellitus
The Outcomes of Intracavernosal Umbilical Cord Mesenchymal Stem Cells Implantation in Patients With Diabetic Erectile Dysfunction
Erectile dysfunction (ED) is a complex condition affecting men worldwide. Diabetes mellitus (DM) is one of the most common causes of ED. The prevalence of ED in DM varies around 35-85%.
- Trial name
- NCT04972890
- Testing
- stem cells
- Where
- Indonesia
- Volunteers
- 12 people
- Sponsor
- Universitas Indonesia
Congenital Heart Disease
Copeptin- Relevance as a Perioperative Marker in Pediatric Cardiac Surgery
This study evaluates the relevance of Copeptin in children with congenital heart disease undergoing cardiac surgery with the need of cardiopulmonary bypass. Three blood samples are taken of each patient.
- Trial name
- NCT03316508
- Where
- Austria
- Volunteers
- 81 people
- Sponsor
- Claudia Herbst
Gestational Diabetes Mellitus
Diet, Exercise, and Breastfeeding Intervention Program for Women With Gestational Diabetes (DEBI Trial)
The primary aim of this study is to evaluate whether a lifestyle intervention of diet, exercise, and breastfeeding is associated with decreased postpartum weight retention and reduced plasma glucose levels, measured at 6-weeks…
- Trial name
- DEBI (NCT00460018)
- Testing
- Diet, Exercise, and Breastfeeding Intervention
- Where
- 5 sites in United States
- Volunteers
- 180 people
- Sponsor
- Kaiser Permanente
Diabetes Mellitus, Type 1
Middle Cerebral and Umbilical Arteries Doppler Indices in the Prediction of Adverse Neonatal Outcome Among Diabetic Pregnant Women
120 patients will be included and divided into two groups; Control group that will include 60 healthy pregnant women and Study group that will include 60 pregestational diabetic pregnant patients which furtherly will be…
- Trial name
- NCT03915990
- Testing
- umbilical and middle cerebral artery Doppler
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Gestational Diabetes
Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes
This study is being done to study how exenatide, an FDA-approved drug that lowers blood sugar in non-pregnant patients with type II diabetes, works in pregnant women.
- Trial name
- NCT05482789
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Maisa N. Feghali, MD
Hypertension, Cardiovascular Disease
Population Based Strategies for Effective Control of High Blood Pressure in Pakistan
Studies have established that high blood pressure (BP) is the most common risk factor for cardiovascular disease (CVD). Despite a heavy burden of hypertension (33% of all persons aged 45 years and over), there are no reliable…
- Conditions
- Hypertension, Cardiovascular Disease, Obesity, Diabetes
- Trial name
- NCT00327574
- Testing
- Home heath education +/_ GP training
- Where
- Pakistan
- Sponsor
- Aga Khan University
Type II Diabetes Mellitus
Evaluation of Innovated Screening Tools for Type 2 Diabetes Among Chinese Population(SENSIBLE STUDY I)
Evaluation of using 2h-UG combined with FPG, AGEsP alone or in combination with FPG in diabetes screening in Chinese natural population
- Trial name
- NCT03025919
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Macrosomia, Fetal, Gestational Diabetes Mellitus in Pregnancy
New Markers of Glycation to Predict Gestational Diabetes Mellitus and Macrosomia.
Gestational diabetes mellitus (GDM) increases the risk of macrosomia and other adverse pregnancy outcomes. Screening strategies are debated: universal vs.
- Trial name
- GLYCAGEST (NCT06048510)
- Testing
- Pregnant women
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Bordeaux
Diabetic Kidney Disease, Hyperuricemia
Uric Acid Lowering Trial in Youth Onset T2D
Adolescents and young adults with youth-onset type 2 diabetes (T2D) are disproportionally impacted by hyperuricemia compared to non-diabetic peers and youth with type 1 diabetes (T1D).
- Conditions
- Diabetic Kidney Disease, Hyperuricemia, Diabetes, Diabetes Mellitus, Type 2
- Trial name
- ULTRA-T2D (NCT03899883)
- Testing
- Pegloticase 8 MG/ML [Krystexxa]
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes Mellitus With Diabetic Nephropathy
Safety and Efficacy of Oral GKT137831 in Patient With Type 2 Diabetes and Albuminuria
NADPH oxidase enzymes (NOX) have been implicated in the development of several diabetic complications including diabetic nephropathy. GKT137831 is the first in class NOX1/4 inhibitor.
- Trial name
- NCT02010242
- Testing
- GKT137831
- Where
- 48 sites in United States, Australia and 4 more
- Volunteers
- 136 people
- Sponsor
- Calliditas Therapeutics AB
Reproductive Health, Gestatiaonl Diabetes Mellitus
Exploring Reproductive Health Among Women in Somaliland
Somaliland faces persistently high burdens of maternal and perinatal mortality, with limited population-based data on pregnancy complications, sociocultural influence on maternal health, and women's reproductive health needs…
- Conditions
- Reproductive Health, Gestatiaonl Diabetes Mellitus, Hypertensive Disorders of Pregnancy, Contraception
- Trial name
- PROMISE (NCT07438379)
- Where
- Somalia
- Volunteers
- 808 people
- Sponsor
- University of Hargeisa
Type 1 Diabetes, Nephropathy
Effects of Probiotics and Fibers on Albuminuria in Persons With Type 1 Diabetes
The primary objective is to assess the impact of three months' treatment with pre-/probiotic mix on markers of nephropathy and other comorbidity related to diabetes.
- Conditions
- Type 1 Diabetes, Nephropathy, Albuminuria, Diabetic Kidney Disease
- Trial name
- ProFOS (NCT04635670)
- Testing
- Pro-/prebiotic Mix
- Where
- Denmark
- Volunteers
- 41 people
- Sponsor
- Steno Diabetes Center Copenhagen
Gestational Diabetes
MyDiabby Healthcare Vs Diary in Gestational Diabetes Mellitus.
The purpose of the study is to demonstrate the non-inferiority of the onset of maternal, foetal, and neonatal complications for patients who had Gestational diabetes mellitus (GDM) and who had been monitored by myDiabby…
- Trial name
- TELESUR-GDM (NCT05510583)
- Testing
- Control group, Treated group
- Where
- France
- Volunteers
- 668 people
- Sponsor
- Hôpital NOVO
Gestational Diabetes, Gestational Hypertension
The Effect of High Dose Folic Acid Versus Placebo on the Rate of Gestational Diabetes or Gestational Hypertension in Pregnant Women
The purpose of this study is to determine if higher-than usual doses of daily folic acid has an effect on the rate of gestational diabetes mellitus (GDM) or gestational hypertension in pregnant women while determining status of…
- Trial name
- NCT01302756
- Testing
- Folic Acid
- Sponsor
- Mike O'Callaghan Military Hospital
Diabetes Mellitus, Type 2, Renal Insufficiency, Chronic
Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (MK-0431-063 AM1)
The purpose of the study is to compare how sitagliptin and glipizide lower blood glucose levels in participants with moderate or severe renal insufficiency.
- Trial name
- NCT00509262
- Testing
- Sitagliptin, Glipizide
- Volunteers
- 426 people
- Sponsor
- Merck Sharp & Dohme LLC
Pre Diabetes, Polycystic Ovary Syndrome
Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS
There is a growing need to develop pharmacologic interventions to improve metabolic function in women with polycystic ovary syndrome (PCOS).
- Conditions
- Pre Diabetes, Polycystic Ovary Syndrome, Obesity Android
- Trial name
- SAXAPCOS (NCT03480022)
- Testing
- Liraglutide Pen Injector [Saxenda]
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Woman's