Clinical trials: Diabetes in Pregnancy
Perioperative Myocardial Injury
Perioperative Copeptin: Predictive Value and Risk Stratification in Patients Undergoing Major Surgery
Observational cohort study examining the perioperative course of copeptin in patients undergoing elevated-risk surgery.
- Trial name
- NCT02687776
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 517 people
- Sponsor
- University Hospital, Basel, Switzerland
Gestational Diabetes
Utility of Real Time Continuous Glucose Monitoring in the Care of Gestational Diabetes Versus Standard Care in Pregnancy Outcomes
Once a pregnant mother is diagnosed with gestational diabetes mellitus (GDM), she will be treated with either diet, medication (i.e., insulin), or both.
- Trial name
- DiP GlucoMo (NCT05037526)
- Testing
- Dexcom G System, Self monitoring blood glucose
- Where
- Switzerland
- Volunteers
- 302 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Gestational Diabetes Mellitus, Pregnancy, High Risk
Continuous Glucose Monitoring (CGM) Substudy of the DECIDE RCT
This is a nested multicenter prospective cohort conducted concurrently and in conjunction with the DECIDE two-arm, pragmatic non-inferiority comparative effectiveness Randomized Controlled Trial (RCT) (NCT06445946) of metformin…
- Trial name
- DECIDE CGM (NCT06490874)
- Testing
- CGM device - Metformin group, CGM device - Insulin group
- Where
- 4 sites in United States
- Sponsor
- Ohio State University
Gestational Diabetes
Gestational Diabetes - PrEvention of PostPartum Diabetes Study
Gestational diabetes is the most common metabolic abnormality during pregnancy. In a Swedish population 2-10% of all pregnant women are diagnosed with gestational diabetes mellitus (GDM).
- Trial name
- PEPP (NCT05112588)
- Testing
- Intervention
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Central Diabetes Insipidus
A Study of Minirin Melt in Japanese Patients With Central Diabetes Insipidus (CDI).
This is an open-label dose-titration study in Japanese Central Diabetes Insipidus (CDI) patients designed to demonstrate the efficacy and safety of orally-disintegrating tablet of desmopressin.
- Trial name
- NCT01280188
- Testing
- Desmopressin Oral Melt, Desmopressin intranasal
- Where
- 5 sites in Japan
- Volunteers
- 20 people
- Sponsor
- Ferring Pharmaceuticals
Postpartum Gestational Diabetes Mellitus
The PPCGMS Intervention After GDM Trial
Among women who experience glucose abnormalities during pregnancy, screening during the postpartum period offers a window of opportunity for early identification of diabetes and prediabetes.
- Trial name
- PPCMS (NCT06057805)
- Testing
- Blinded Dexcom G7 CGM
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Woman's
Gestational Diabetes Mellitus in Pregnancy
The Effect of E-Health Management on Gestational Diabetes Control
The purpose of this study was to develop an e-heath management platform(eHMP) for women with high risk of gestational diabetes mellitus (GDM) and to evaluate the longitudinal effects between groups of eHMP intervention.
- Trial name
- NCT03726983
- Testing
- Experimental group
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Chang Gung Memorial Hospital
Diabetic Nephropathy
Nephropathy In Type 2 Diabetes and Cardio-renal Events
The NID-2 study, a multicentric study (21 centres enrolled), was planned in two phases: Phase 1(observational study, completed in September 2005): after the identification of a type-2 diabetic population with typical Diabetic…
- Trial name
- NID-2 (NCT00535925)
- Testing
- SoC therapy, irbesartan, ramipril
- Where
- Italy
- Volunteers
- 850 people
- Sponsor
- University of Campania Luigi Vanvitelli
Sarcopenia, Gestational Diabetes Mellitus (GDM)
Sarcopenia in Gestational Diabetes
Sarcopenia is a syndrome characterized by loss of skeletal muscle mass and strength, and physical performance deterioration. Prevalence of sarcopenia in elderly people is remarkably high (prevalence of about 25% in 60+ years…
- Conditions
- Sarcopenia, Gestational Diabetes Mellitus (GDM), Pregnancy Complications, Adverse Maternal and Neonatal Outcomes
- Trial name
- SiGnal-D (NCT06876090)
- Testing
- Sarcopenia tests (for muscle mass, muscle function, physical performance), Oral Glucose Tolerance Test, Montreal Cognitive Assessment
- Where
- 3 sites in Austria, Italy
- Volunteers
- 200 people
- Sponsor
- Istituto di Neuroscienze Consiglio Nazionale delle Ricerche
Gestational Diabetes Mellitus in Pregnancy
Acarbose and Prandial Insulin for the Treatment of Gestational Diabetes Mellitus.
Caring for women with gestational diabetes mellitus (GDM) is very time-consuming. Therapeutic strategy includes dietary and lifestyle measures and additional insulin therapy for 15 to 40% of the women with GDM if the glycemic…
- Trial name
- ACARB-GDM (NCT03380546)
- Testing
- Acarbose, Prandial insulin
- Where
- France
- Volunteers
- 341 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 1, Albuminuria
Effect of Butyrate on Inflammation and Albuminuria in Patients With Albuminuria, Type 1 Diabetes and Intestinal Inflammation
The objective is to assess the impact of 12 weeks supplement of sodium-butyrate twice daily or placebo on intestinal inflammation and albuminuria.
- Trial name
- NCT04073927
- Testing
- Sodium butyrate
- Where
- 2 sites in Denmark, Finland
- Volunteers
- 48 people
- Sponsor
- Steno Diabetes Center Copenhagen
Bladder Cancer, Diabetes Mellitus
The Feasibility of a Diet and Exercise Intervention in Diabetics During Treatment for Non-muscle Invasive Bladder Cancer
The purpose of this study is to learn if bladder cancer patients can follow a diet and exercise program during treatment and whether the program will improve results of their treatment.
- Trial name
- DEAL (NCT02716623)
- Testing
- CR diet, Exercise
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- University of Kansas Medical Center
Gestational Diabetes
Glycated Albumin in Pregnancy
This is an observational study at the Obstetrical outpatient clinic at Stavanger University Hospital, Norway. The purpose of the study is to compare glycated albumin and glycated hemoglobin (HbA1c), both markers of "long-term…
- Trial name
- NCT03372824
- Where
- Norway
- Volunteers
- 148 people
- Sponsor
- Helse Stavanger HF
Cardiac Arrest
Comparing Vasopressin and Adrenaline in Patients With Cardiac Arrest
The effectiveness of medications in cardiac arrest has been greatly debated and questioned. Historically intravenous adrenaline has been the drug of choice since 1906.
- Trial name
- PIVOT (NCT00358579)
- Testing
- Adrenaline, Vasopressin
- Where
- 4 sites in Singapore
- Volunteers
- 727 people
- Sponsor
- Singapore General Hospital
Gestational Diabetes
A Study Using Breath Tests to Identify Patients at Risk for Gestational Diabetes
The aim of our study is to evaluate the feasibility, and diagnostic value of oral 13C labelled glucose breath test compared to the GCT and OGTT tests.
- Trial name
- NCT07347262
- Testing
- Noninvasive Breath Test in Order to Identify Patients at Risk for Developing Gestational Diabetes
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Exercise, Mobile Health
Monitored Home Exercise in Pregnancy
The Study Investigators intend to study the adherence to and effect of a prescribed, monitored at-home exercise regimen in a pregnant population at risk for gestational diabetes, with a specific goal of understanding factors…
- Conditions
- Exercise, Mobile Health, Pregnancy, Gestational Diabetes
- Trial name
- NCT03551535
- Testing
- Monitored, At-Home Exercise Intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Diabetic Nephropathies
This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Tolerated
The primary objective of this current trial is to investigate the safety and tolerability of 3 oral doses of BI 690517 over 28 days in female and male patients with diabetic nephropathy as add-on-therapy to Angiotensin Converting…
- Trial name
- NCT03165240
- Testing
- BI 690517, Eplerenone
- Where
- 40 sites in Denmark, France and 8 more
- Volunteers
- 62 people
- Sponsor
- Boehringer Ingelheim
Diabetes
Physical Activity and Functioning in Home Dialysis Patients
This study will compare physical activity levels and physical functioning in patients treated with home dialysis vs. those treated with in-center dialysis.
- Trial name
- NCT01602718
- Testing
- exercise training
- Volunteers
- 120 people
- Sponsor
- University of Utah
Chronic Kidney Disease
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort
This study will evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single ascending doses (SAD) and multiple ascending doses (MAD) of AZD4248 administered as an oral solution and intravenous (IV)…
- Trial name
- NCT07024823
- Testing
- AZD4248
- Where
- 5 sites in United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Gestational Diabetes
Impact of Blood Glucose at the First Trimester of Pregnant Women With Gestational Diabetes on Maternal and Fetal Outcomes and Metabolic Disorders: a Multi-central Prospective Cohort Study
The study is to investigate the impact of blood glucose management at the first trimester of pregnant women with gestational diabetes on the maternal and fetal outcomes and metabolic disorder.
- Trial name
- NCT01833559
- Testing
- Dietary control, Insulin
- Where
- China
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
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