Clinical trials: Diabetes type1
Type 1 Diabetes
Effects of Vitamin D Supplementation in Subjects With New Onset of Type 1 Diabetes
In this placebo controlled study the investigators aim to investigate the effects of vitamin D supplementation in subjects with new onset of type 1 diabetes on immunological, endocrine and metabolic parameters.
- Trial name
- NCT01390480
- Testing
- Cholecalciferol
- Where
- Austria
- Volunteers
- 31 people
- Sponsor
- Medical University of Graz
Diabetes Mellitus, Type 1, Diabetic Nephropathy
Matrix Metalloproteinases and Diabetic Nephropathy
Matrix metalloproteinases (MMPs) are a family of protein-degrading enzymes that are involved in the breakdown and remodeling of many tissues and organs.
- Trial name
- NCT00067886
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Diabetes
Satisfaction of Specific Modes Related to Physical Activity in People Living With Type 1 Diabetes and Using an Hybrid Closed-loop System
The BF-ACT study is a single-center, non-interventional (RIPH3) descriptive study conducted at CHU Grenoble Alpes. It aims to evaluate the satisfaction of adults with type 1 diabetes using closed-loop insulin delivery systems…
- Trial name
- BF-ACT (NCT07567170)
- Testing
- Questionnar
- Where
- France
- Volunteers
- 900 people
- Sponsor
- University Hospital, Grenoble
Type 1 Diabetes Mellitus, Adolescent Behavior
Using an mHealth App to Transition Care of Type-1 Diabetes From Parents to Teens
Type 1 diabetes (T1D) afflicts approximately 154,000 people under the age of 20. Most people with T1D are diagnosed at a young age; their parents have to manage their child's condition.
- Conditions
- Type 1 Diabetes Mellitus, Adolescent Behavior, Parent-Child Relations, Communication
- Trial name
- NCT03436628
- Testing
- MyT1DHero
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Type 1 Diabetes
Effectiveness of Empagliflozin Added to Automated Insulin Delivery (AID) Systems in Adults With Type 1 Diabetes With Sub-optimal Glycemic Outcomes
The goal of this 26-week multicenter, randomized, parallel, placebo-controlled trial is to test the effectiveness of empagliflozin use in conjunction with automated insulin delivery (AID) to improve glucose control in individuals…
- Trial name
- NCT06021145
- Testing
- Empagliflozin
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Diabetes Mellitus, Type 1
Algorithm to Control Postprandial, Post Exercise and Night Glucose Excursions in a Portable Closed Loop Format
In previous studies, we tested the feasibility of a bi-hormonal closed loop system. This system for automated control of blood glucose in patients with type 1 diabetes was tested in the clinical research center as well as at the…
- Trial name
- APPEL4 (NCT02160275)
- Testing
- Artificial Pancreas (Inreda Diabetic BV), Insulin pump therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 16 people
- Sponsor
- J.H. DeVries
Type 1 Diabetes
Islet Transplantation in Type 1 Diabetic Patients
Our hypothesis is that a successful clinical islet transplant program can be established at the University of Wisconsin using a steroid -free, sirolimus- and low dose tacrolimus - based immunosuppressive drug regimen (Edmonton…
- Trial name
- NCT00214253
- Testing
- Thiazolidinedione
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Wisconsin, Madison
Osteoporosis Secondary, Diabetes Mellitus, Type 1
the Type ONe dIabetic Bone Collaboration Study
In this cross-sectional clinical study, we will examine the bones of 111 Type 1 Diabetes (T1D) patients and 37 age-matched healthy controls with the aim of describing a T1D Bone Phenotype.
- Trial name
- TONICS (NCT05673837)
- Where
- Denmark
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Type 1 Diabetes
Evaluation of Long-Term Implanted Sensor in Patients on Quality of Life
Evaluation of Long-Term Implanted Sensor in Patients on Quality of life
- Trial name
- NCT04161651
- Testing
- eversense
- Volunteers
- 22 people
- Sponsor
- Meir Medical Center
Type 1 Diabetes (T1D)
Food Prescription Among Youth With Type 1 Diabetes
The purpose of this study is to assess the feasibility and preliminary outcomes of a healthy eating program that consists of Food Rx combined with an evidence-based healthy eating family behavioral intervention refined for…
- Trial name
- NOURISH (NCT07860229)
- Testing
- Healthy Eating Program
- Volunteers
- 45 people
- Sponsor
- Baylor College of Medicine
Diabetes, Diabetes Mellitus, Type 1
A Trial Investigating the Pharmacokinetic Properties of FIAsp in Japanese Subjects With Type 1 Diabetes
This trial is conducted in Japan. The aim of the trial is to evaluate the pharmacokinetic (the exposure of the trial drug in the body) and pharmacodynamic (the effect of the trial drug on the body) properties of FIAsp…
- Trial name
- NCT01934712
- Testing
- Faster-acting insulin aspart, insulin aspart
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Novo Nordisk A/S
Insulin Pump Therapy
Closed Loop Pumps vs. Traditional Open Loop Pumps in Managing Blood Glucose Levels in T1DM Patients Fasting in Ramadan.
Our proposed study aims to build upon the existing findings by conducting a first-of-its-kind randomized controlled trial (RCT) that directly compares Advanced Hybrid Closed Loop (AHCL) and open-loop insulin delivery (OLID)…
- Trial name
- HybridRam (NCT06416202)
- Testing
- Advanced hybrid closed loop insulin pump, Open Loop Insulin Delivery system
- Where
- Saudi Arabia
- Volunteers
- 75 people
- Sponsor
- King Fahad Medical City
Diabetes Mellitus, Type 1
Improving HbA1c Levels Through Behavioural Change of Diabetes Self-management Assisted by the LovedBy Mobile Application for Young Adults and Adolescents With Type 1 Diabetes
Young people (16-25) with type-1 diabetes have historically struggled with managing their condition. Typically, the average HbA1c levels are significantly higher and as such, the risk of long term complications tend to be far…
- Trial name
- LBY-T1 (NCT05217953)
- Testing
- LovedBy App
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Diabetes, Diabetes Mellitus, Type 1
NovoLet® Acceptance Study Within the Hospital Practise in Indonesia
This study is conducted in Asia. The aim of this study is to evaluate the overall acceptance of healthcare professionals (nurses and doctors) to the NovoLet® system used in a hospital environment.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT01492205
- Testing
- insulin human
- Where
- Indonesia
- Volunteers
- 203 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Investigation of Correlation Between Concentrations of Glucose in Blood and Interstitial Fluid in Type 1 Diabetics
This is a mono-centre trial performed at the Center for Clinical Research at the Medical University Graz. There will be a screening information and a study visit.In the study visit arterialized venous blood glucose values will be…
- Trial name
- NCT00499954
- Testing
- Microdialysis, Guardian RT, Glucoday S
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Graz
Diabetes Mellitus Type 1
A Monocenter, Open-Label Glucose Clamp Study Examining the Metabolic Effect of Insulin Infusion Intervals for Basal Insulin Infusion in Patients With Type I Diabetes
This crossover, glucose-clamp study will investigate the impact of different basal insulin infusion rates on glucose control employing insulin pumps with different insulin delivery regimen.
- Trial name
- NCT00772356
- Testing
- Accu-Chek Spirit Insulin Pump, Comparator insulin pump
- Where
- Germany
- Volunteers
- 14 people
- Sponsor
- Hoffmann-La Roche
Type 1 Diabetes
The Steno Free Trial: AID to Adults with New-onset of Type 1 Diabetes
Since the introduction of insulin therapy 100 years ago, significant progress has continuously been made in the treatment of people with type 1 diabetes.
- Trial name
- NCT06586632
- Testing
- AID technology, CGM
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Type 1 Diabetes
Remote Monitoring of CGM Data in Pediatric Patients With Newly Diagnosed Type 1 Diabetes (T1D)
To determine if increased targeted contact between patients and the care team can improve diabetes outcomes in the 1st year after diagnosis.
- Trial name
- NCT03968055
- Testing
- Integration with Epic
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Type 1 Diabetes
Context Aware Data Gathering Study
Automated Insulin Delivery (AID) systems have now become an important standard-of-care for people with T1D and have demonstrated a reduction, but not elimination, of hypoglycemia during long-term studies.
- Trial name
- NCT04154904
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Type 1 Diabetes (T1D)
NO-Meal Announcement in Automated Insulin Delivery (Open-source and Commercial) Systems
Automated insulin delivery (AID) systems are the current gold standard for the management of type 1 diabetes (T1D), improving glycemic control, reducing hypoglycemia, and decreasing treatment burden.
- Trial name
- NOMAD (NCT07758647)
- Testing
- Open-Source Automated Insulin Delivery (OS-AID), Commercial Automated Insulin Delivery (C-AID)
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Institut de Recherches Cliniques de Montreal