Clinical trials: Diabetes-Related Complications
Peripheral Neuropathy, Diabetic Neuropathies
Focal Vibrations and Neuropathic Pain in Diabetic Peripheral Neuropathy
Most of the literature found on whole body vibrations(WBV) instead of focal muscle vibrations (FMV) in diabetic peripheral neuropathy patients.
- Trial name
- NCT05322746
- Testing
- Focal muscle vibration
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Riphah International University
Hypoglycemia, Infant, Small for Gestational Age
Dextrose Gel Does Not Prevent Neonatal Hypoglycemia
This was a quasi-experimental pilot study comparing blood glucose values 30 minutes after feeding alone or feeding + dextrose gel in newborns at risk for transient neonatal hypoglycemia.
- Conditions
- Hypoglycemia, Infant, Small for Gestational Age, Premature Birth of Newborn, Fetal Macrosomia
- Trial name
- NCT02523222
- Testing
- 40% Dextrose gel
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Baylor College of Medicine
Type 1 Diabetes Mellitus
The Effect of Uric Acid Lowering in Type 1 Diabetes
Patients with type 1 diabetes mellitus (T1DM) are at high risk of developing kidney complications potentially leading to end stage renal disease.
- Trial name
- NCT02344602
- Testing
- Febuxostat
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Diabetic Ketoacidosis
Association of Systemic Immune-inflammation Index and Severity of Diabetic Ketoacidosis in Type 1 Diabetes Mellitus
Diabetic ketoacidosis (DKA) is the most serious metabolic complication of type 1 diabetes mellitus (T1DM). Insulin deficiency and inflammation play a role in the pathogenesis of DKA.
- Trial name
- NCT06251895
- Testing
- DKA protocol
- Where
- Kuwait
- Volunteers
- 241 people
- Sponsor
- Jahra Hospital
Hypertension, Diabetic Nephropathy
A Study in Patients With Diabetes Mellitus Type II of the Effect on Albuminuria of 24 Week Treatment With Valsartan, Benazepril, and Valsartan+Benazepril
The purpose of this study is to evaluate the efficacy of valsartan, benazepril or the combination of both in reduction of microalbuminuria in Type 2 diabetic patients.
- Trial name
- NCT00171119
- Testing
- valsartan
- Where
- Switzerland
- Volunteers
- 81 people
- Sponsor
- Novartis Pharmaceuticals
Diabetic Retinopathy
Correlation Between Macular Ischemia and Peripheral Ischemia in Patients With Diabetes
The contribution of OCT- angiography (OCT-A) allows to consider, in a more or less long term, a drastic reduction in the use of fluorescein angiographies in diabetic retinopathy.
- Trial name
- CORISMAP (NCT02876744)
- Testing
- ophthalmologic examination
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Diabetic Kidney Disease
Impact of Multidisciplinary Self-care Management of Diabetic Nephropathy on Quality of Life, Self-care Behavior, Glycemic Control, and Renal Function.
Diabetic Kidney Disease (DKD) is becoming a global health concern that affects largely the elderly population. Despite advances in pharmacological and management strategies, DKD remain associated with high morbidity and…
- Trial name
- NCT01967901
- Testing
- Self-care management program
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Applied Sciences of Western Switzerland
Diabetic Neuropathy
Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of AV411 in Neuropathic Pain
The purpose of this study is to determine the safety, tolerability and pharmacokinetics of AV411 after single and multiple doses in patients with chronic neuropathic pain due to diabetes.
- Trial name
- NCT00576277
- Testing
- AV411
- Where
- 2 sites in Australia
- Volunteers
- 36 people
- Sponsor
- Avigen
Pain
Intravitreal Injection Site and Perceived Pain
The objective of this study is to explore the perception of pain during intravitreal injection related to the distance of the entry site from the limbus.
- Trial name
- NCT05640895
- Testing
- Intravitreal injection site
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Diabetic Retinopathy, Macular Edema
Triple Therapy of Pars Plana Vitrectomy and Grid/Focal Laser for Diabetic Macular Edema (DME)
This study is designed to report 3-year result of triple therapy of vitrectomy, intravitreal triamcinolone and macular laser photocoagulation for intractable diabetic macular edema.
- Trial name
- NCT01202461
- Testing
- Triple therapy of vitrectomy, IVTA and grid/focal laser photocoagulation
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- Samsung Medical Center
Diabetic Neuropathy
The Effect of Random Vibrations on Perception and Balance
The purpose of this study is to investigate the effects of vibrating insoles on vibration perception threshold (VPT) and balance of people with diabetic neuropathy.
- Trial name
- NCT02989831
- Testing
- Vibrating insoles 'on'
- Volunteers
- 40 people
- Sponsor
- University Medical Center Groningen
Diabetic Kidney Disease (DKD), Type 2 Diabetes
The Relationship Between Psychological Well-being, Social Support, and Disease Self-management in Patients With Diabetic Nephropathy
This study will look at the psychological well-being and social support of people with diabetic kidney disease and how these factors are related to how well they manage their condition.
- Trial name
- NCT07726589
- Where
- Taiwan
- Volunteers
- 161 people
- Sponsor
- National Taiwan University Hospital
CKD, Diabetic Kidney Disease
Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy
This randomized study evaluates the effect of subcutaneous semaglutide /in combination with lifestyle counseling in patients with type 2 diabetes mellitus (T2DM), overweight/obesity, and stage 4-5 chronic kidney disease (CKD) or…
- Conditions
- CKD, Diabetic Kidney Disease, Type 2 Diabetes Mellitus in Obese, Obesity
- Trial name
- RAISE-KT (NCT04741074)
- Testing
- Semaglutide 2 mg/1.5 ml (1.34 mg/ml), prefilled pen-injector for subcutaneous injection solution
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Geisinger Clinic
Insulin-Dependent Diabetes Mellitus 1
Prevalence of DRP and DME Among Type 1 Diabetics Treated With Long-term Intensified Insulin Therapy
This study is designed to evaluate the prevalence of different stages of diabetic retinopathy and diabetic macular edema among patients suffering from type 1 diabetes (DM 1) for 5 to 25 years and have been treated with…
- Trial name
- NCT02307110
- Testing
- cross-sectional observation
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Vista Klinik
Diabetic Foot Ulcer, Lower Extremity Amputation
Comparison of Anesthetic Modalities on Hemodynamic Stability and Postoperative Pain in Diabetic Foot Patients Undergoing Minor Lower Extremity Amputation
Diabetic foot ulcer is the most common cause of non traumatic lower extremity amputations (LEA) associated with diabetes. Traditionally general and spinal anesthesia were the preferred modality of anesthesia.
- Trial name
- NCT02440282
- Volunteers
- 86 people
- Sponsor
- Yonsei University
Diabetic Retinopathy, Low Vision
Diabetic Retinopathy Tethered Augmented Reality With Eye4 Study
Diabetes has reached epidemic levels in North America and with it, diabetic retinopathy is increasingly affecting the vision of millions of people.
- Trial name
- DRTARES (NCT05491746)
- Testing
- Eye4
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Eyedaptic
Polyneuropathy, Diabetic
Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt
The purpose of the study is to find out whether ALA is effective and safe for treating Egyptian diabetic patients with symptomatic polyneuropathy.
- Trial name
- MIRACLE-ALA (NCT05813496)
- Testing
- Alpha-Lipoic Acid (ALA)
- Where
- 5 sites in Egypt
- Volunteers
- 430 people
- Sponsor
- Eva Pharma
Gestational Diabetes, Pregnancy Related
Studying Phenotypes of Gestational Diabetes Mellitus in an Asian Pregnant Cohort
Gestational diabetes mellitus (GDM) is a transient hyperglycemic condition identified during pregnancy in women without a history of chronic diabetes.
- Conditions
- Gestational Diabetes, Pregnancy Related, Pregnancy Complications, Birth Weight
- Trial name
- GDM-CARE (NCT06542718)
- Where
- Singapore
- Volunteers
- 800 people
- Sponsor
- National University Health System, Singapore
Open-angle Glaucoma, Diabetic Retinopathy
Safety and Efficacy of Anti-Oxidants and Anti-inflammatory Agents in Glaucoma and Diabetic Retinopathy
This study is a multi-armed protocol designed to evaluate the safety and efficacy of two different combinations of nutritional supplements (study drug) (Glauco-Health and Glauco-Select) chosen for their potential to protect…
- Trial name
- NCT02984813
- Testing
- GlaucoHealth, GlaucoSelect
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The New York Eye & Ear Infirmary
Diabetic Foot, Amputation
Predictors of Foot Amputation in Diabetic Foot Ulcers
Diabetes affects 463 million population of the world. Diabetic foot is one of the complications of uncontrolled diabetes which can lead to amputation in 5- 24% of non-healing diabetic foot ulcers.
- Conditions
- Diabetic Foot, Amputation, Antibiotic Resistant Strain, Diabetic Foot Ulcer
- Trial name
- NCT05551988
- Testing
- Retrospective observational study of diabetic foot ulcer
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Bolan Medical Complex Hospital Quetta Pakistan
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