Clinical trials: Diabetes-Related Complications
Diabetic Nephropathy Type 2
Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cell Therapy in Diabetic Nephropathy Patients: A Clinical Trial
The goal of this clinical trial is to evaluate the safety and efficacy of a single intra-renal injection of allogeneic umbilical cord-derived mesenchymal stem cells (UC-MSCs) in adults with diabetic nephropathy aged 40 to 65…
- Trial name
- NCT07396155
- Testing
- Umbilical Cord Mesenchymal Stem Cells
- Where
- Indonesia
- Volunteers
- 10 people
- Sponsor
- PT. Prodia Stem Cell Indonesia
Diabetes, Diabetic Retinopathy
Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus
This study aims to integrate clinical indicators and features of fundus images, combined with metabolomics, to construct an early warning model for diabetic retinopathy (DR) in type 2 diabetes.
- Conditions
- Diabetes, Diabetic Retinopathy, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- NCT06821399
- Testing
- Fundus Examination, Metabolomics analysis
- Where
- 3 sites in China
- Volunteers
- 2,920 people
- Sponsor
- Yufan Wang
Diabetic Foot Ulcer, Ulcer Foot
Resorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data on 2 commercially available SOC dressings treatments for Diabetic Foot Wounds
- Conditions
- Diabetic Foot Ulcer, Ulcer Foot, Diabetic Foot
- Trial name
- NCT03398538
- Testing
- Offloading, Additional (outer) Dressing Application, Mirragen Wound Matrix Dressing
- Where
- 5 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ETS Wound Care, LLC
Diabetic Retinopathy
Investigating the Retardation Effect of OCTA-Guided Targeted Photocoagulation on the Progression of Non-Perfusion Areas in Diabetic Retinopathy Patients
This study aims to evaluate the impact of widefield OCTA-guided selective photocoagulation on the progression of diabetic retinopathy (DR) by comparing the control of non-perfusion (NP) areas, DR grading, and management of other…
- Trial name
- NCT06821633
- Testing
- Targeted laser photocoagulation guided by OCTA (Optical Coherence Tomography Angiography)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sichuan Provincial People's Hospital
Foot Ulcer, Diabetic
Study to Determine the Feasibility of Using an At-home Foot Temperature Monitoring Device (Thermidas)
This is a feasibility study, designed to assess the acceptability of At Home Temperature Monitoring (AITM) by patients at high risk of diabetes foot ulceration.
- Trial name
- NCT06032221
- Testing
- Thermidas Vista Telehealth App
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Diabetic Neuropathies, Neuropathic Pain
Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy
This study evaluates the analgesic effect of Omnitram for the treatment of painful diabetic neuropathy. Each subject with diabetic neuropathy will be treated for four weeks with Omnitram and for four weeks with placebo.
- Conditions
- Diabetic Neuropathies, Neuropathic Pain, Pain, Chronic
- Trial name
- NCT03664921
- Testing
- Omnitram Oral Tablet
- Where
- 4 sites in United States
- Volunteers
- 55 people
- Sponsor
- Syntrix Biosystems, Inc.
Diabetic Foot Ulcer
Omega3 Wound Fish Skin Graft in the Treatment of DFUs
The purpose of this clinical evaluation is to collect patient outcome data on a commercially available 510K FDA-approved product that is derived from minimal processing of Atlantic cod fish skin: KerecisTM Omega3 Wound.
- Trial name
- NCT04133493
- Testing
- Kerecis Omega3 Wound, Fibracol
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kerecis Ltd.
Foot Ulcer, Diabetic
Reduction of Plantar Pressure in Neuropathic Diabetic Foot Patients Using Insoles With Removable Pegs Design
The purpose of this study was to determine if insoles with removable pegs could effectively reduce the plantar aspect pressure with the aid of in-shoe plantar pressure analysis for guidance of peg removal.
- Trial name
- NCT01699100
- Testing
- device
- Volunteers
- 26 people
- Sponsor
- Taichung Veterans General Hospital
Diabetes Complications, Fatty Liver
Effects Of Exenatide On Liver Biochemistry, Liver Histology And Lipid Metabolism In Patients With Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are common complications of type 2 diabetes and leading causes of liver disease in the US and Europe.
- Trial name
- NCT00529204
- Testing
- exenatide
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, Davis
Foot Ulcer, Diabetic
Approaches to Foot Complication Prevention: A Survey of Diabetes Educators
The purpose of the survey is to assess the knowledge base, role in management, and resources available to diabetes educators regarding foot complication prevention within a variety of healthcare settings.
- Trial name
- NCT04400344
- Testing
- No intervention
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Podimetrics, Inc.
Diabesity
Establishment of Hong Kong Diabesity Register
All participants of the Diabesity Register will receive structured assessment by nurses guided by the JADE portal at baseline including eye, feet, blood and urine examination with evaluation of BMI, blood pressure, HbA1c, lipid…
- Trial name
- NCT07247409
- Testing
- No Intervention: Observational Cohort
- Where
- Hong Kong
- Volunteers
- 800 people
- Sponsor
- Chinese University of Hong Kong
Diabetic Foot
Study of Subjects With Diabetic Foot Ulcer (DFU)
Foot ulceration is a common and costly complication of diabetes. GSK1278863 is a topical drug, which is being developed to treat wounds associated with DFU.
- Trial name
- NCT03153007
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus
Assessment of Tissue Oxygenation Using Multispectral Imaging
In Canada, the age-standardized prevalence of diabetes is on the rise (increasing from 3.3% in 1998/99 to 5.6% in 2008/2009 Public Health Agency of Canada (July 2011)) and is almost 1 in 10 globally.
- Trial name
- NCT03516864
- Testing
- MIMOSA Imager, Kent Camera
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Diabetic Retinopathy, Macula Edema
Transfoveal Micropulse Laser for Center Involving Diabetic Macular Edema
Anti-vascular endothelial growth factor (VEGF) therapy is currently the mainstay of treatment for diabetic macular edema (DME). One of the main obstacles of anti-VEGF therapy is the need of repeated injections, which carries both…
- Trial name
- NCT04359771
- Testing
- Yellow micro-pulse laser, Diode micro-pulse laser
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Cairo University
Diabetic Foot
Negative Pressure Wound Therapy in Diabetic Wounds
Topical Negative Pressure Wound Therapy (TNPW) is an established tool in the management of Diabetic foot ulcer in many countries. This treatment option is under utilized in the public sector of Mauritius.
- Trial name
- NCT05041244
- Testing
- Negative pressure wound therapy delivered through VAC, Standard of care
- Where
- Mauritius
- Volunteers
- 80 people
- Sponsor
- University of Mauritius
Diabetic Foot Ulcer
Effect On Paın And Anxıety Of Stress Ball Use Durıng Sharp Debrıdement
Diabetic foot ulcer; It is a disease used to describe a series of lower extremity complications that may occur together with infection, ulceration or gangrene in individuals with diabetes and is coded as S91.3 and S91.8 in the…
- Trial name
- NCT06316115
- Testing
- In Patıents Wıth Dıabetıc Foot Ulcer, Effect On Paın And Anxıety Of Stress Ball Use Durıng Sharp Debrıdement
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Harran University
Diabetic Retinopathy, Age-Related Macular Degeneration
Function and Structure Imaging in Different Retinal Diseases: Retinal Leakage Analyzer Versus Optical Coherence Tomography
The main objective of this observational study is to characterize and correlate functional and structural changes at the retinal level using the Retinal Leakage Analyzer (RLA) and the Optical Coherence Tomograph (OCT).
- Conditions
- Diabetic Retinopathy, Age-Related Macular Degeneration, Macular Edema
- Trial name
- NCT00797524
- Where
- Portugal
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Diabetic Foot
Clinical Trial for the Treatment of Diabetic Foot Ulcers Using a Nitric Oxide Releasing Patch: PATHON
Diabetes Mellitus constitutes one of the most important public health problems due to its high prevalence and enormous social and economic consequences.
- Trial name
- NCT00428727
- Testing
- Controlled nitric oxide releasing patch
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Cardiovascular de Colombia
Diabetes and Risk of Diabetic Foot Ulcer, Diabetes Mellitus
An Analysis of Plantar Pressure Distribution and Postural Balance Parameters in Individuals With Diabetic Foot Diagnosis
This study aims to investigate the relationship between plantar pressure distribution and postural balance in individuals diagnosed with diabetic foot.
- Conditions
- Diabetes and Risk of Diabetic Foot Ulcer, Diabetes Mellitus, Postural Control, Plantar Pressure Distrubution
- Trial name
- NCT07084922
- Testing
- No interventions. This is an observational study where participants undergo assessments of plantar pressure and postural balance without any treatment or intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medipol University
Diabetic Retinopathy, Clinically Significant Macular Edema
Reduction of Foveal Sensitivity in Eyes With Diabetic Macular Edema
Clinically significant macular edema (CSME) is a thickening of the macula associated with the risk of visual loss, which increases its centre is involved.
- Trial name
- NCT01824862
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Juarez de Mexico
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