Clinical trials: Diabetic
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population
The study aims to assess foot complications among patients with diabetes in Canada, using patient data collected during diabetes foot assessments performed by the LMC Chiropody Team between February 27, 2018 and April 17, 2019.
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Foot Deformities, Onychauxis
- Trial name
- PEDAL (NCT04327622)
- Where
- Canada
- Volunteers
- 5,084 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Type 2 Diabetes Mellitus
Efficacy Study of Pioglitazone and Metformin and Association Between Pioglitazone Response and Peroxisome Proliferator-activated Receptor Gamma Gene Variants in Bangladeshi Type 2 Diabetes Mellitus Subjects
The present study was undertaken to assess the efficacy and safety of two different insulin sensitizers (namely Pioglitazone and Metformin) among subjects with type 2 diabetes mellitus (T2DM) in Bangladesh.
- Trial name
- T2DMCT (NCT01589445)
- Testing
- Pioglitazone hydrochloride, Metformin hydrochloride
- Where
- Bangladesh
- Volunteers
- 77 people
- Sponsor
- University of Dhaka
Critical Limb Ischemia
Autologous Bone Marrow Stem Cell Transfer in Patients With Chronical Critical Limb Ischemia and Diabetic Foot
A total of 90 patients suffering from end stage-IV Fontaine /CLI and diabetic foot with an ulcerated limb in whom all previous therapeutic strategies failed (e.g.
- Trial name
- NCT01232673
- Testing
- BMAC application in Critical Limb Ischemia
- Volunteers
- 96 people
- Sponsor
- University Hospital Ostrava
Stroke
Effects of Aerobic Training in Diabetic vs Non-Diabetic Post-Stroke Patients
The study aims to investigate the effects of aerobic training in post-stroke patients, both diabetic and non-diabetic, in terms of their metabolic response to exercise and psychosocial well-being.
- Trial name
- NCT06450054
- Testing
- Aerobic Exercise in diabetic post-stroke patients, Aerobic Exercise in Non diabetic post-stroke patients
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Superior University
Pain, Diabetic Neuropathy
Study to Evaluate the Analgesic Efficacy of 28 Days' Oral Administration of AZD2066 Compared With Placebo in Patients With Painful Diabetic Neuropathy
The purpose of this study is to investigate if AZD2066 can relieve the pain arising from painful diabetic neuropathy compared to placebo.
- Trial name
- NCT00857623
- Testing
- AZD2066
- Where
- 19 sites in United States
- Volunteers
- 127 people
- Sponsor
- AstraZeneca
Diabetes, Diabetes Mellitus, Type 1
A Survey to Evaluate Diabetes Management, Control, Chronic Complications, Psychosocial Aspects of Diabetic Subjects in Thailand
This study is conducted in Asia. The aim of this observational study is to evaluate current status of diabetes management, control, complications in diabetic subjects in Thailand.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- DiabCare Asia (NCT00805922)
- Testing
- No treatment given
- Where
- Thailand
- Volunteers
- 2,342 people
- Sponsor
- Novo Nordisk A/S
Periodontitis, Type 2 Diabetes Mellitus
Diagnostic Biomarkers Related to Periodontal Disease Activity in Diabetic
The purpose of the study was to monitor the activity of periodontal disease and suggest potential biomarkers related to active periodontal disease in patients with chronic periodontitis (PD) associated or not with type 2 diabetes…
- Trial name
- NCT02220751
- Testing
- non-surgical periodontal therapy + systemic doxycycline, Non-surgical periodontal therapy
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Diabetes Mellitus
Demographic, Clinical, and Biomedical Profile of Diabetic Patients Receiving Home Healthcare in Saudi Arabia
Background: Identifying characteristics of diabetic patients receiving home healthcare will help in designing services that respond to their conditions and improve their health status and quality of life.
- Trial name
- NCT05918653
- Testing
- Home Healthcare
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 252 people
- Sponsor
- Saudi Scientific Home Health Care Society
Cardiovascular Abnormalities, Chronic Kidney Diseases
Characteristics, Treatment, and Economic Burden of Patients With CVD,CKD or at High Cardiovascular Risk
The heavy disease burden is mainly due to diabetic complications. Diabetes is a major risk factor for cardiovascular disease (CVD) and chronic kidney disease (CKD).China has been the largest absolute disease burden of diabetes in…
- Conditions
- Cardiovascular Abnormalities, Chronic Kidney Diseases, Diabetes
- Trial name
- NCT03958760
- Where
- China
- Volunteers
- 200,000 people
- Sponsor
- West China Hospital
Type 2 Diabetes Mellitus
Quality Initiative to Improve Glucose Control in Type 2 Diabetic Patients
The goal of the Twine / University of Michigan Diabetes Quality Improvement Initiative is to improve diabetes care quality using real time feedback with continuous glucose monitoring (CGM) and dietary coaching for lower…
- Trial name
- NCT03705260
- Testing
- Usual Care, Intensive Behavioral Intervention, Monthly Screening for Risk
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Michigan
Peripheral Neuropathy, Diabetic Neuropathies
Efficacy of Moxibustion in Diabetes Peripheral Neuropathy
This pragmatic randomized controlled study aimed to evaluate the effectiveness and safety of moxibustion therapy on diabetes peripheral neuropathy.
- Trial name
- NCT04894461
- Testing
- Moxibustion
- Volunteers
- 40 people
- Sponsor
- Xiamen University
Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU)
Evaluation of the Safety and Efficacy of Dehydrated Human Placenta Tissue (dHPT) for Wound Healing
The retrospective trial is observational, intended to stand alone, complement and integrate data collected in ongoing clinical studies to aid in establishing payor coverage in the United States (U.S.) for Cellution Biologics…
- Conditions
- Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU), Pressure Ulcer (PU)
- Trial name
- RETRO-PLAST (NCT07375160)
- Testing
- dHPT, AIC
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Cellution Biologics
Diabetic Macular Edema
Safety and Effect of Intravitreal Injection of a Derivative of Nucleoside Reverse Transcriptase Inhibitor in Subjects with Diabetic Macular Edema
This study is designed to assess the safety and initial evidence of efficacy of the novel compound SOM-401 (K8), a derivative of a nucleoside reverse transcriptase inhibitor, in subjects with untreated, clinically significant…
- Trial name
- NCT05699759
- Testing
- K8
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Michelle Abou-Jaoude
Diabetic Foot Ulcer, Venous Leg Ulcer
DETEC® Esterase for Screening Wound Infection at Point of Care
This non-interventional, single-blinded, prospective, observational study assesses the planar distribution of leukocyte esterase in wounds by placing wound exudates soaked wound dressings in the DETEC® Esterase device during…
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer
- Trial name
- NCT04614870
- Testing
- DETEC® Esterase
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Progenitec Inc.
Diabetes
Capability Assessment for Diet and Activity (CADA) Model for Diabetes
This study investigates the capabilities related to diet, physical activity, screening, and knowledge among diabetic adults with or without a history of hospital admissions in Central Florida.
- Trial name
- NCT06631105
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Central Florida
Type 2 Diabetes
Hope Theory as Ability Determinant to Permanently Change the Adapted Physical Activity (APA) in Type 2 Diabetic Patients
The control of diabetes is related both to food, treatment but also to physical activity. Despite these recommendations and these positive findings, patients are always sedentary because of brakes in the practice of a regular…
- Trial name
- APADIAB-ESPOIR (NCT02733302)
- Testing
- Hope theory
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Angers
Diabetes Mellitus, Physical Activity
Evaluation of the Benefit at 6 Months of a 3 Weeks Spa Treatment in the Type 2 Diabetic Patient.
Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia due to deficiency in either insulin secretion, insulin action, or both. There are different types of diabetes.
- Conditions
- Diabetes Mellitus, Physical Activity, Dietetic Rules, Therapeutic Education
- Trial name
- DIABEO2THERMES (NCT03912623)
- Testing
- SPA Treatment with therapeutic education and physical activity, Week end
- Where
- 9 sites in France
- Volunteers
- 200 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Retinal Neovascularization
Squalamine for the Treatment in Proliferative Diabetic Retinopathy
The purpose of this study is to determine the efficacy in the use of topical Squalamine Lactate Ophthalmic Solution, 0.2% in the treatment of retinal neovascularization resulting from proliferative diabetic retinopathy.
- Trial name
- NCT01769183
- Testing
- Squalamine Lactate ophthalmic solution 0.2%
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Elman Retina Group
COVID-19
Macrophage Activation Markers in COVID-19 Patients
This study is aiming to find the relation between the severity of COVID-19 in diabetic and obese patients and the high serum levels of matrix metalloproteinase-7 (MMP-7),matrix metalloproteinase-9 (MMP-9), TGF-β and PDGF…
- Trial name
- COVID-19 (NCT04766294)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sohag University
Diabetes, Gestational, Gastric Bypass Status for Obesity Complicating Pregnancy, Childbirth, or the Puerperium
Gestational Diabetes After Gastric Bypass Surgery
The goal of this trial is to compare different means of glucose monitoring in women with gestational diabetes and a history of gastric bypass surgery.
- Conditions
- Diabetes, Gestational, Gastric Bypass Status for Obesity Complicating Pregnancy, Childbirth, or the Puerperium, Pregnancy in Diabetic, Blood Glucose Self Monitoring
- Trial name
- NCT06291766
- Testing
- FreeStyle Libre 2, continous glucose monitoring
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane