Clinical trials: Diabetic Feet
Diabetic Foot Ulcer
Shockwave Therapy of Chronic Diabetic Foot Ulcers
Introduction: Foot ulcers are a feared complication among diabetic patients. The ulcers can cause pain, discomfort and reduced quality of life. The development of foot ulcers places the patients at a risk of amputation.
- Trial name
- NCT02251418
- Testing
- Extracorporeal shockwave therapy
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Odense University Hospital
Diabetic Foot, Staphylococcal Infections
Standard Treatment Associated With Phage Therapy Versus Placebo for Diabetic Foot Ulcers Infected by S. Aureus
The primary objective of this study is to compare the efficacy of standard treatment associated with a topical anti-staphylococcal bacteriophage cocktail versus standard treatment plus placebo for diabetic foot ulcers…
- Trial name
- PhagoPied (NCT02664740)
- Testing
- Topical anti-Staphylococcus bacteriophage therapy
- Where
- 6 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Dressing, Self-dressing
Dressing Method (Self-dressing vs. Nurse-led Dressing) on Healing Outcomes in Diabetic Foot Ulcers
This study aimed to compare the efficacy of self-dressing and nurse-led dressing on healing outcomes in diabetic foot ulcers (DFUs) .
- Conditions
- Dressing, Self-dressing, Nurse-led Dressing, Healing
- Trial name
- NCT07602491
- Testing
- Self-dressing, Nurse-led dressing
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU)
Evaluation of the Safety and Efficacy of Dehydrated Human Placenta Tissue (dHPT) for Wound Healing
The retrospective trial is observational, intended to stand alone, complement and integrate data collected in ongoing clinical studies to aid in establishing payor coverage in the United States (U.S.) for Cellution Biologics…
- Conditions
- Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU), Pressure Ulcer (PU)
- Trial name
- RETRO-PLAST (NCT07375160)
- Testing
- dHPT, AIC
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Cellution Biologics
Diabetic Foot, Diabetic Foot Ulcer
Shear Load In-shoe Plantar Sensing/Strain Analyses and Mapping in Diabetic Foot Ulcers
Stain Analysis Mapping of the Plantar surface (STAMP) is a method designed by the University of Leeds to measure 'in-shoe' strain patterns on the plantar surface of the foot.
- Trial name
- SLIPSTREAM (NCT05687643)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Diabetic Foot Ulcer
Effect of Local Application of Boron on Diabetic Foot Ulcers
Boron as a naturally occurring element has some metabolic and inflammatory actions. The antibacterial activity against gram negative bacteria is also known.
- Trial name
- NCT02087215
- Testing
- boron gel
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bezmialem Vakif University
Diabetic Foot Ulcers
TruSkin®: Study for the Treatment of Chronic Diabetic Foot Ulcers
The purpose of this study is to compare the clinical outcomes of TruSkin® and an Active Comparator in patients with chronic diabetic foot ulcers.
- Trial name
- NCT02936115
- Testing
- TruSkin®, Wound Cover
- Where
- 5 sites in United States
- Volunteers
- 14 people
- Sponsor
- Osiris Therapeutics
Diabetic Foot Ulcer
The Effect of Implementing a Limb Loss Prevention Program on Amputation Rates
The investigators plan to do a retrospective chart review on patients admitted to Parkland Hospital with diabetic foot infections, ulcers, and bone injuries from 2005 (5 years prior to the start of the diabetic limb preservation…
- Trial name
- NCT03978715
- Testing
- No intervention-retrospective study
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetic Foot Ulcer (DFU), Venous Leg Ulcers (VLUs)
HEAL-4: Real-World Effectiveness of 4 Amniotic Allografts Adjunctive to Standard Care in DFU, VLU, and PU
This retrospective multi-site observational cohort study uses electronic health records (EHR) from U.S. wound care centers to evaluate the effectiveness of four amniotic membrane allografts (Acesso DL, Acesso TL, Neostim DL…
- Conditions
- Diabetic Foot Ulcer (DFU), Venous Leg Ulcers (VLUs), Pressure Ulcers, Bedsores, Decubitus Ulcer
- Trial name
- HEAL-4 (NCT07223515)
- Where
- 2 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Dynamic Medical Services dba Acesso Biologics
Diabetic Feet
How Shoes With Rocker Soles Affect Walking
The purpose of this study is to compare how 3 special types of shoes with rocker-shaped soles help people with foot deformities to walk better.
- Trial name
- NCT00006438
- Testing
- Shoes with Rocker Soles
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Limb Salvage, Diabetes Complication
This Observational Study Evaluates the Clinical Outcomes of Patients With Diabetes Who Utilize a Specialized Dietary Supplements for Foot Ulcer Healing. The Study Documents the Rate of Complete Wound Closure and the Prevention of Lower Extremity Amputations in a Real-world, At-home Setting.
This observational study evaluates the clinical outcomes of patients with diabetes who utilize a specialized dietary supplements for foot ulcer healing.
- Conditions
- Limb Salvage, Diabetes Complication, Dietary Supplements, Healed Ulcer
- Trial name
- NCT07442110
- Testing
- Diabetic foot ulcer treatment by dietary supplements
- Where
- Algeria
- Volunteers
- 35 people
- Sponsor
- Amar h Zireg
Diabetic Foot Ulcer, Deep Diabetic Foot Ulcer
Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers
Diabetes-related foot ulcers (DFUs) are a leading cause of hospitalization and amputation worldwide, and account for 33% of all direct costs of diabetes care in the US.
- Trial name
- NCT03476876
- Testing
- Dermacell, Integra
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Baylor College of Medicine
Diabetic Foot Ulcer (DFU), Lower Extremity
Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers
This study will evaluate Matrion™ (LifeNet Health, Inc., Virginia Beach, VA), a placental membrane product, as a treatment for diabetic foot ulcers compared to conventional wound care.
- Trial name
- NCT07116876
- Testing
- Graft Application, Wound Dressing Material
- Where
- 17 sites in United States
- Volunteers
- 120 people
- Sponsor
- LifeNet Health
Diabetic Foot Infection, Osteomyelitis
A Clinical Trial Testing the Efficacy of PDT in Preventing Amputation in Diabetic Patients
The feet of diabetic patients continue to be an important problem in medicine. In general, patients with diabetic foot have some sort of amputation, especially in underserved populations.
- Conditions
- Diabetic Foot Infection, Osteomyelitis, Photo Antimicrobial Chemotherapy
- Trial name
- NCT03380403
- Testing
- PDT, Ciprofloxacin
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Faculdade de Medicina do ABC
Diabetic Foot
Diabetic Foot Ulcer Prevention System (DFUPS) - Part 2
The purpose of this study is to investigate whether regular measurement of skin foot temperature with a novel device (DFUPS) will prevent ulcer recurrence in diabetic patients at high risk of foot ulceration.
- Trial name
- DFUPS (NCT02579070)
- Testing
- DFUPS
- Where
- 3 sites in United Kingdom
- Volunteers
- 110 people
- Sponsor
- King's College Hospital NHS Trust
Diabetic Foot Ulcer
Comparative Study of Two Application Regimens of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers
The purpose of this study is to determine whether a weekly application of EpiFix human amniotic membrane is more effective than a biweekly application (every two weeks) in the treatment of diabetic foot ulcers.
- Trial name
- NCT01657474
- Testing
- Weekly application of EpiFix plus standard of care, Biweekly application of EpiFix plus standard of care
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- MiMedx Group, Inc.
Reflexology, Type 2 Diabetes
Effect of Reflexology on Diabetic Foot and Glycemic Control in Elderly Diabetic Individuals
Background: Glycemic control can be difficult in the elderly with diabetes.Diabetic foot problems characterized by vascular and neuropathy are serious complications.
- Conditions
- Reflexology, Type 2 Diabetes, Older People
- Trial name
- NCT04416503
- Testing
- Foot reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Abant Izzet Baysal University
Diabetic Foot, Type 2 Diabetes Mellitus With Established Diabetic Nephropathy
The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region
Objectives: Preventing diabetic foot problems (DFP) and associated consequences, such as amputation, is a critical in rural regions.
- Trial name
- NCT01299246
- Testing
- Michigan Neuropathy Screening Instrument
- Where
- Taiwan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Negative-Pressure Wound Therapy, Diabetic Foot
Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds
The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.
- Trial name
- NCT05716503
- Testing
- Negative Pressure Wound Therapy (NPWT), Ordinary dressings with antibiotic ointment and gauze
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Diabetic Neuropathies, Painful, Diabetic Foot
Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain
The purpose of this research is to assess whether the use of a topical cream with an active ingredient can reduce the amount of foot pain experienced in participants who have been diagnosed with Diabetic Peripheral Neuropathy…
- Conditions
- Diabetic Neuropathies, Painful, Diabetic Foot, Diabetic Peripheral Neuropathy
- Trial name
- NCT07260656
- Testing
- Capsaicin Palmitate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Carilion Clinic
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