Clinical trials: Diabetic Feet
Diabetic Neuropathic Foot Ulcers
CHF6467 SAD and MAD in Patients With Diabetic Foot Ulcer
To assess the safety and tolerability of single and multiple days' topical dosing with CHF6467 in subjects with diabetic foot ulcer (DFU).
- Trial name
- NCT04077671
- Testing
- CHF6467 active
- Where
- Bulgaria
- Volunteers
- 93 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Diabetic Foot Ulcer
Use of Remote Thermovisual Monitoring in Patients With a Previous Diabetic Foot Ulcer
The goal of the clinical trial is to investigate adherence to, and effects of, the Bluedrop Monitoring System (BMS) in high-risk patients with at least one previous diabetic foot ulcer (DFU).
- Trial name
- NCT05039645
- Testing
- Patient specific, clinician determined Intervention
- Where
- 2 sites in Ireland, United Kingdom
- Volunteers
- 31 people
- Sponsor
- Bluedrop Medical Limited
Diabetic Foot Ulcer, Deep Diabetic Foot Ulcer
Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers
Diabetes-related foot ulcers (DFUs) are a leading cause of hospitalization and amputation worldwide, and account for 33% of all direct costs of diabetes care in the US.
- Trial name
- NCT03476876
- Testing
- Dermacell, Integra
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Baylor College of Medicine
Hammer Toe Syndrome, Foot Ulcer, Diabetic
Flexor Tenotomy and Ulcer Recurrence
The main purpose of this study is to assess the efficacy of flexor tenotomy on the prevention of recurrence of toe ulcers in people with diabetes and a history of toe ulceration.
- Trial name
- NCT05228340
- Testing
- Flexor tenotomy
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Diabetes Complications, Diabetes Education
Impact of an Educational Intervention on Ulcer Incidence, Knowledge, Self-Care, and Quality of Life in Diabetic Foot Syndrome
This randomized clinical trial assessed the impact of a structured educational intervention in patients with diabetic foot syndrome.
- Conditions
- Diabetes Complications, Diabetes Education, Diabetes Foot Care
- Trial name
- NCT07329491
- Testing
- Structured education intervention, Standard podiatry care
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Universidad Complutense de Madrid
Ischemia Limb, Diabete Mellitus
Comparative Study of Negative-Pressure Wound Therapy Integrated With Silver Nanoparticle Spray Versus Negative-Pressure Wound Therapy in Post-Revascularization Diabetic Foot Wound Management
This was a prospective, parallel-group, randomized controlled trial conducted at the Vascular Surgery Department of Kafrelsheikh University Hospital, Egypt.
- Trial name
- SNIPS-FOOT (NCT07147790)
- Testing
- After successful revacularization, We will categorize patients into two groups : groups A (The patient's wound will be cleaned and irrigated with silver nanoparticle spray, then we will cover the woun, Silver Nanoparticles Irrigant
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
Chronic Wound, Burn Wound
Wound Healing Endpoint and Recurrence
This study is a continuation of a previously approved protocol conducted at Ohio State University and Indiana University. The first two aims of the original protocol have been completed, and this protocol will finish enrollment…
- Conditions
- Chronic Wound, Burn Wound, Diabetic Foot Ulcers, Pressure Ulcers
- Trial name
- NCT02577120
- Testing
- Epiceram Skin Barrier Function, Vaseline Petroleum Jelly
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Sashwati Roy
Diabetes, PAD
Micro-mobile Foot Compression and Diabetic Foot
Diabetic foot ulceration (DFU) is a common and largely preventable complication. While most of these ulcers can be treated successfully, some will persist and become infected.
- Conditions
- Diabetes, PAD, Lower Extremity Edema, Neuropathy;Peripheral
- Trial name
- NCT03135535
- Testing
- Avex Footbeat
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Diabetic Foot Ulcer
Bioactive Smart Dressings for Diabetic Foot Ulcers: Randomized Controlled Trial
We propose a randomized controlled study to assess the efficacy of: 1. Platelet-lysate loaded sustained release thermo-gelling formulation (Platelets-SR) 2.
- Trial name
- NCT05671250
- Testing
- PRP gel and SOC-treatment, EPO/ISDN/UFH cryogel dressing, Standard of Care
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Diabetic Foot Ulcer, Diabetic Foot
Quality of Life and Self-care in Patients With Diabetic Foot Ulcers Treated With Low-level Laser Therapy
Diabetic foot ulcers (DFU) are aggressive complications of diabetes mellitus (DM) and affect 25% of these patients. DFU are associated with a high risk of amputations and early mortality and significantly impact quality of life…
- Trial name
- NCT05071235
- Testing
- LG1 (LLLT group 1), LG2 (LLLT group 2), LG3 (LLLT group 3)
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of Piaui
Diabetic Foot Ulcers
Evaluate the Safety and Efficacy of RegenKit Autologous PRP Gel for the Treatment of Diabetic Foot Ulcer
Autologous platelet-rich plasma (PRP) gel was reported to have very good outcomes in the treatment of foot ulcers in pilot studies and retrospective uncontrolled trials.
- Trial name
- NCT02402374
- Testing
- Autologous platelet rich plasma gel
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Regen Lab SA
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Diabetic Peripheral Neuropathy (DPN)
TRPM8 Activators for Peripheral Neuropathy
The goal of this pilot prospective cohort study is to evaluate the efficacy of a novel hand and foot mask in alleviating symptoms of peripheral neuropathy caused by chemotherapy or diabetes.
- Trial name
- NCT07583797
- Testing
- Hand and Foot Mask
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- SHIANG-SUO HUANG
Diabetic Foot Ulcer, Amputation
Herbal Preparation Used as Adjuvant Therapy on Diabetic Ulcers
Chronic foot ulcers occurring among diabetic patients are difficult to heal. The frequent elderly age with co-morbidities, vascular insufficiencies, peripheral neuropathies and super imposed infections, all contribute towards the…
- Trial name
- NCT00393510
- Testing
- TCM
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Diabetic Foot Ulcer
GrafixPL PRIME Evaluation Case Study
The investigators plan to evaluate healing in a cohort of patients with chronic wounds (n=40) that receive optimal treatment including serial wound debridement and off-loading with total contact casts or a boot and GrafixPL…
- Trial name
- NCT03742440
- Testing
- GrafixPL PRIME
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetic Foot Ulcers
A Trial Examining Cellular Energetics Related to Various Wound Treatment Therapies
A randomized, controlled pilot study examining how cellular energetics related to various wound treatment therapies in patients with diabetic foot ulcers.
- Trial name
- NCT00605189
- Testing
- Powered Suction Pump (VAC Freedom), Powered Suction Pump, MWT
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- KCI USA, Inc
Diabetic Foot
A Sympathetic Ganglion, High-voltage Pulsed Radiofrequency Ablation of Peripheral Neuralgia
The Sham Operation Group was used as control, the patients were assessed with the Digital Rating Scale (NRS) , the quality of life-related scale (Euro Qol) , clinical outcome measures: physician's overall impression of changes in…
- Trial name
- NCT05831059
- Testing
- Pulsed radio frequency therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Diabetic Foot Ulcer
Comparison Between the Effect of Ultrasound Debridement and Conventional Treatment in Diabetic Foot Ulcers (DFU).
The investigators aimed to elucidate the effects of ultrasound debridement on the area and healing of diabetic foot ulcers compared to their conventional treatment.
- Trial name
- NCT04716790
- Testing
- Ultrasound Debridement, Conventional Treatment
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad Complutense de Madrid
Diabetic Foot Ulcer, Foot Ulcer
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
This Phase 3 study is a randomized, double-blind, vehicle-controlled, multiple-center, parallel study to evaluate efficacy and safety of ENERGI-F703 GEL compared with vehicle control in subjects with Wagner Grade 1 to Grade 2…
- Conditions
- Diabetic Foot Ulcer, Foot Ulcer, Diabetes Mellitus, Wound
- Trial name
- NCT05930210
- Testing
- ENERGI-F703 GEL, ENERGI-F703 matched vehicle
- Where
- 24 sites in United States, Taiwan
- Volunteers
- 230 people
- Sponsor
- Energenesis Biomedical Co., Ltd.
Diabetic Foot
Effect of Anesthesia Technique on Early Outcome in Diabetic Patients Undergoing Lower Extremity Amputation
The aim of this study was to compare 1. early prognosis (mortality, morbidity) 2. changes in concentrations of serum syndecan-1,partial pressure of oxygen(on arterial blood gas analysis), perioperative transfusion, intraoperative…
- Trial name
- NCT04063046
- Testing
- General anesthesia, Peripheral nerve block
- Where
- South Korea
- Volunteers
- 158 people
- Sponsor
- Yonsei University
Diabetic Foot Xerosis
Evaluation of the Effects of the Product RV5075A-MF6793 in Diabetic Patients Presenting Foot Xerosis and Superficial Fissures, an Exploratory Study.
This exploratory study is meant to assess the efficacy of a product in diabetic patients presenting foot xerosis and superficial fissures This exploratory study will be conducted as randomized, comparative study in parallel…
- Trial name
- NCT06997718
- Testing
- RV5075A MF6793, CO5075A
- Where
- Portugal
- Volunteers
- 62 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
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