Clinical trials: Diabetic Feet
Foot Ulcers, Diabetic, Foot Ulcer Unhealed
SALACIA: SALvesAn vs Conventional Management of dIAbetic Foot Wounds
Increasing prevalence of diabetes mellitus has led to increasing numbers of chronic non-healing foot ulcers (wounds). Electrolysed water is a novel antiseptic which reduces bacterial load and appears to encourage wound healing.
- Trial name
- SALACIA (NCT06908148)
- Testing
- Electrolysed water, Conventional irrigant
- Volunteers
- 200 people
- Sponsor
- NHS Lanarkshire
Chronic Diabetic Foot Ulcer
Fespixon Cream for the Treatment of Chronic Diabetic Foot Ulcers (TEXAS 1A, 2A) in Dialysis Patients
Evaluate the Safety and Efficacy of Fespixon Cream for the Treatment of Chronic Diabetic Foot Ulcers (TEXAS 1A, 2A) in dialysis patients This study aimed to evaluate the effects of a topical cream containing Plectranthus…
- Trial name
- NCT05338463
- Testing
- Fespixon Cream
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- Cathay General Hospital
Diabetic Foot Ulcer, Venous Leg Ulcer
Efficacy and Tolerance of URGO AWC_008 and URGO AWC_022 Dressings (EXPANSION)
Evaluation of the efficacy (wound epithelialization and time to closure) and tolerance (emergence and nature of adverse event) of the new URGO AWC_008 and URGO AWC_022 dressings in local management of acute and chronic wounds at…
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound Infection
- Trial name
- NCT05772507
- Testing
- URGO AWC_008 dressing or URGO AWC_022 dressing
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Laboratoires URGO
Diabetic Foot Ulcers
A Prospective Study of Endothelial Dysfunction and Diabetic Foot Ulcer Risk
This project will identify risk factors for diabetic foot ulcer by studying the relationship between endothelial dysfunction and foot ulcer risk.
- Trial name
- NCT00013286
- Testing
- Prevention Diabetic Foot Ulcer
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- US Department of Veterans Affairs
Wounds, Diabetic Foot Ulcers
Evaluation of a 'Hand-held' Fluorescence Digital Imaging Device for Real-Time Advanced Wound Care Monitoring (JDRTC/UHN)
We have developed an innovative optical molecular imaging platform (called PRODIGI) based on high-resolution fluorescence and white-light technologies in a hand-held, real-time, high-resolution, non-invasive format.
- Trial name
- JDRTC/UHN (NCT01651845)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University Health Network, Toronto
Diabetic Foot Ulcers
MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers
224 adults with diabetic foot ulcers will be randomized to either magainin peptide (MSI-78) or ofloxacin (FLOXIN, Ortho-McNeil Pharmaceutical Corporation) an oral fluoroquinolone antibiotic.
- Trial name
- NCT00563394
- Testing
- ofloxacin, MSI-78
- Where
- United States
- Volunteers
- 584 people
- Sponsor
- Abeona Therapeutics, Inc
Chronic Wounds With Different Etiologies
Swab Sample Collection for the Detection of Bacterial Proteases in Wounds Assay
The objective of this study is to collect wound exudate (fluid) swab samples from Subjects who have wounds that show clinical signs of infection, as well as from Subjects who have wounds that do not show clinical signs of…
- Trial name
- NCT01750203
- Testing
- Swabs
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Systagenix Wound Management
Diabetic Foot Ulcer
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers
Diabetic foot ulcer (DFU) is one of the most invalidating complication of diabetes and represents a big economic burden for the society.
- Trial name
- DEFEHU (NCT03137966)
- Testing
- Deferoxamine
- Volunteers
- 174 people
- Sponsor
- Karolinska University Hospital
Diabetic Foot Disease, Chronic Kidney Disease Due to Type 2 Diabetes Mellitus
Predictors of Diabetic Foot Outcome in Chronic Kidney Disease Patients
Individuals with diabetic neuropathy and Chronic kidney disease (CKD) are 15 times more likely to have a non-traumatic lower extremity amputation compared to those with DM alone .
- Trial name
- NCT06684886
- Testing
- Ankle Brachial Index
- Volunteers
- 60 people
- Sponsor
- Assiut University
Diabetic Ulcers on Both Feet, Amputation; Traumatic, Limb
The Impact of Sexual Health and Amputation Focused Education on Regulation of Glucose and Amputation Prevention
The purpose of this study is to investigate the effect of two types of education on HbA1c level and future amputations in inpatient diabetics after initial minor foot amputation
- Conditions
- Diabetic Ulcers on Both Feet, Amputation; Traumatic, Limb, Sexual Dysfunction, Diabetic Foot Ulcer Ischemic
- Trial name
- NCT04078854
- Testing
- Diabetes education
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Montefiore Medical Center
Diabetic Foot Ulcers
Safety Study of Topical Human FGF-1 for Wound Healing
The purpose of the study is to see if FGF-1 is safe when applied topically to the surface of a wound.
- Trial name
- NCT00916292
- Testing
- FGF-1 141
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Phage Pharmaceuticals, Inc.
Diabetic Foot
Implementation of Foot Thermometry and SMS and Voice Messaging to Prevent Diabetic Foot Ulcer
This study aims to implement daily temperature measurements of feet complemented by SMS and voice messaging to prevent diabetic foot ulcers in patients with type 2 diabetes mellitus at high risk of ulceration.
- Trial name
- NCT02373592
- Testing
- SMS and voice messaging, Thermometry
- Where
- 2 sites in Peru
- Volunteers
- 172 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Diabetes Mellitus, Diabetic Foot Ulcer
Relaxation Intervention in Patients With Diabetic Foot Ulcer
Diabetic foot ulcers (DFU) are one of the most serious complications of diabetes and can lead to amputations in 85% of cases, resulting in physical, psychological, family, social and economic consequences.
- Trial name
- NCT04652999
- Testing
- Muscle Relaxation with Guided Imagery, Neutral Guided Imagery
- Where
- 2 sites in Portugal
- Volunteers
- 54 people
- Sponsor
- University of Minho
Diabetic Foot, Wound
Extracorporeal Shockwave Therapy for Diabetic Foot Wounds
Diabetic wounds post digital amputation have poor healing in 30-45% of cases, resulting in 75% of patients undergoing a further amputation within the year, despite best wound management.
- Trial name
- NCT04042285
- Testing
- Extracorporeal shockwave therapy in addition to standard care
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Diabetic Foot, Infections
Toe Amputations in Patients With Diabetes
This study is a randomized controlled trial (RCT) to evaluate outcome after toe amputation due to diabetic foot infection. Aim of this RCT is to evaluate wound healing and functional outcome based, whether wound is closed or left…
- Conditions
- Diabetic Foot, Infections, Amputation
- Trial name
- PANDORAT (NCT05855980)
- Testing
- Wound closure
- Where
- Finland
- Volunteers
- 102 people
- Sponsor
- Tampere University Hospital
Diabetic Foot, Stem Cell
Stem Cell Derived Exome for Treatment of Diabetic Foot
This trial is designed to investigate the safety and efficacy of patients with diabetic foot by using stem cell derived exome.
- Trial name
- NCT06480123
- Testing
- Skin drug prepared with exome originated from stem cell
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Diabetic Foot Ulcer
Efficacy and Safety of Garamycin® Sponge in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection
The purpose of this study is to determine whether Garamycin Sponge (Gentamicin-Collagen sponge) in combination with antibiotics is safe and effective in treating moderate and severe diabetic foot infections.
- Trial name
- NCT01951768
- Testing
- Garamycin Sponge (Gentamicin-Collagen sponge), Systemic Antibiotic
- Where
- Switzerland
- Volunteers
- 88 people
- Sponsor
- University Hospital, Geneva
Diabetes Mellitus, Diabetic Neuropathies
Smart Insoles for Improving Sensation, Balance and Mobility in People With Diabetic Peripheral Neuropathy.
The long-term effects of vibrating insoles on improving gait, balance and peripheral sensation in people with diabetic peripheral neuropathy remain unknown.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathies, Unsteadiness
- Trial name
- Pathfeel (NCT06855420)
- Testing
- Vibration on, Vibration off
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Walk With Path
Diabetic Foot Ulcers (DFU), Foot Ulcer Chronic
Evaluating the Durability of Closure for Diabetic Foot Ulcers Following a Randomized, Controlled, Modified Platform Trial.
Prospective long-term follow-up on durability of closure evaluated by photographic and thermal scanning.
- Conditions
- Diabetic Foot Ulcers (DFU), Foot Ulcer Chronic, Ulcer, Diabetic Foot Ulcer
- Trial name
- SCANX (NCT07360418)
- Testing
- Blue Drop Foot Scanner
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Applied Biologics, LLC
Diabetic Amputation Foot Wound
A Study Comparing V.A.C. Negative Pressure Wound Therapy (NPWT) to Moist Wound Therapy (MWT) in the Treatment of Diabetic Foot Amputation Wounds
The objective of this study is to thoroughly examine the role of V.A.C. NPWT in the further salvage of the diabetic foot once it has undergone partial amputation.
- Trial name
- VAC 2006-19 (NCT00837096)
- Testing
- V.A.C. Therapy, Moist wound therapy (MWT)
- Volunteers
- 19 people
- Sponsor
- KCI USA, Inc
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