Clinical trials: Diabetic Feet
Diabetic Foot Ulcer
Effectiveness of Vaporous Hyperoxia Therapy (VHT) in the Treatment of Chronic Diabetic Foot Ulcers
The purpose of this study is to evaluate the effectiveness of Vaporous Hyperoxia Therapy (VHT) for the treatment of Diabetic Foot Ulcers.
- Trial name
- VHTDFU2 (NCT04210609)
- Testing
- Vaporous Hyperoxia Therapy
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Vaporox
Diabetic, Neuropathic
Insole Optimisation for Ulcer Prevention: a Feasibility Trial
Insoles are designed to reduce increased loads and re-ulceration risk in patients with diabetes. The investigators previous research findings suggest that an instant insole solution may benefit some, but effectiveness is…
- Conditions
- Diabetic, Neuropathic, Past Ulceration
- Trial name
- NCT01948479
- Testing
- Optimised instant offloading insole
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Plymouth
Critical Limb Ischemia
Dissolved Oxygen Dressing to Improve Chronic Wound Healing After Revascularization for Critical Limb Ischemia
A Prospective, Randomized, Single-center Pilot Study of The OxyGenesys(TM) Dissolved Oxygen Dressing to Improve Chronic Wound Healing after REvascularization for Critical Limb Ischemia.
- Trial name
- NCT02046226
- Testing
- Oxygenesys(TM) Dissolved Oxygen Dressing
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Halyard Health
Anesthesia, Regional
Safety and Efficacy of Three Local Block Techniques for Diabetic Foot Surgery
Diabetic patients suffering diabetic foot disease have sever comorbidities, as hypertension, ischemic heart disease, autonomic neuropathy, infections and gastric reflux all of which contribute to a high risk profile for…
- Trial name
- NCT03155568
- Testing
- sciatic nerve block, ankle block, Bupivacaine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Ulcer, Skin Ulcer
Olivamine-containing Products in the Management of Patients With Nonhealing Lower Extremity Ulcers
In this study, the investigators hypothesize that the use of olivamine-containing products in the management of patients with compromised nonhealing lower extremity ulcers is feasible in the Philippine setting.
- Conditions
- Ulcer, Skin Ulcer, Leg Ulcer, Diabetic Foot
- Trial name
- NCT01657318
- Testing
- Olivamine containing wound care products
- Where
- Philippines
- Volunteers
- 5 people
- Sponsor
- De La Salle University Medical Center
Chronic Wounds, Diabetic Foot Ulcer
Subcutaneous Dexpanthenol Administration and Wound Epithelialization
Chronic wounds are wounds that do not heal properly over time and can significantly reduce quality of life. Common types include diabetic foot ulcers, venous leg ulcers, and arterial ulcers.
- Conditions
- Chronic Wounds, Diabetic Foot Ulcer, Venous Leg Ulcers, Arterial Ulcer
- Trial name
- DEXPAN-WOUND (NCT07395674)
- Testing
- Dexpanthenol, Standard Wound Care
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Dilara CANBAY OZDEMIR
Refractory Diabetic Foot Neuropathic Pain
Short-term SCS for Refractory Diabetic Foot Neuropathic Pain
This single-center, assessor-blinded randomized controlled trial enrolls 88 patients with drug-refractory diabetic foot neuropathic pain unsuitable for revascularization surgery.
- Trial name
- NCT07740707
- Testing
- Standardized Routine Diabetic Foot Therapy, Standard Routine Therapy + 14-day Short-term Spinal Cord Stimulation
- Volunteers
- 88 people
- Sponsor
- Nanchong Central Hospital
Foot Ulcer, Diabetes Mellitus
Diabetic Foot Ulcers Microbiome and Pathogen Identification
This research is being done because people with diabetes have reduced healing capacity and prone to develop infections of foot wounds.
- Conditions
- Foot Ulcer, Diabetes Mellitus, Wound
- Trial name
- NCT05556954
- Testing
- Wound debridement
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- University of Michigan
Toenail Fungal Infection, Cellulitis
A Subjective Observational Study of Patients Using Medicated Footbath/Footwash Treatment in Podiatry Care
The purpose of this study is to evaluate the level of relief perceived by patients using medicated footbath/footwash with or without an oral medication for the treatment of podiatry issues.
- Conditions
- Toenail Fungal Infection, Cellulitis, Pitted Keratolysis, Diabetic Foot Ulcer
- Trial name
- NCT03781024
- Testing
- Footwash
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Data Collection Analysis Business Management
Diabetic Foot Ulcers
Evaluation of ABSOLVE in Diabetic Foot Ulcers
ABSOLVE Biologic Wound Matrix is a combination of recombinant human platelet-derived growth factor BB homodimer (rhPDGF-BB) and a bovine type I collagen wound dressing matrix.
- Trial name
- ABSOLVE (NCT03037970)
- Testing
- RhPDGF-BB
- Where
- Guatemala
- Volunteers
- 40 people
- Sponsor
- Lynch Biologics LLC
Diabetic Foot, Amputation, Surgical
Analyzing Anesthetic Techniques in Diabetic Foot Amputation
Diabetic Foot Amputations: A Comprehensive Review of Anesthetic Procedures and Outcomes Introduction: Diabetic foot is a severe complication of diabetes, often resulting in ulceration, osteomyelitis, and gangrene.
- Trial name
- NCT06552910
- Testing
- Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Ankara City Hospital Bilkent
Diabetes, Foot Ulcer
Hyperbaric Oxygen Therapy as Adjunctive Treatment of Chronic Diabetic Foot Ulcers
The purpose of this study is to evaluate if hyperbaric oxygen therapy heels more foot ulcers as compared to placebo in patients with diabetes mellitus and chronic foot ulcers.
- Conditions
- Diabetes, Foot Ulcer, Healing
- Trial name
- HODFU (NCT00953186)
- Testing
- hyperbaric air, HBOT
- Where
- Sweden
- Volunteers
- 94 people
- Sponsor
- Mrs. Thelma Zoegas Foundation
Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU)
PAW-Hydrogel for Chronic Wound Healing
The goal of this randomized controlled trial is to evaluate the efficacy and safety of a novel hydrogel made of Carbopol® 940 functionalized with Plasma-Activated Water (PAW) in patients with chronic wounds (diabetic foot ulcers…
- Conditions
- Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU), Wound Dehiscence, Venous Leg Ulcer
- Trial name
- NCT07541196
- Testing
- PAW-Functionalized Carbopol® 940 Hydrogel, Standard Advanced Wound Care
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Benjamín Gonzalo Rodríguez Méndez
Ulcer Foot
Transcutaneous CO₂ Therapy in Recurrent Hard-to-Heal Diabetic Foot Ulcers
Recurrent and hard-to-heal diabetic foot ulcers (DFUs) represent a clinically challenging subgroup with delayed closure and frequent non-response to standard of care (SOC).
- Trial name
- NCT07418073
- Testing
- transcutaneous application of gaseous CO2 on lower part of the body
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Diabetic Foot Ulcer
Autologous Platelets Rich Plasma (APRP) Treatment Vs Saline Dressing for the Management of Diabetic Foot Ulcer
The aim of this study is to compare between the platelet rich plasma and normal saline dressing in the healing diabetic foot ulcers. It will be a randomized controlled trial.
- Trial name
- APRP (NCT03716141)
- Testing
- Autologous Platelets Rich Plasma Treatment, Conventional Saline dressing
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Services Hospital, Lahore
Diabetic Foot Ulcer
The Feasibility of a Facebook Group-based Program for Foot Self-management Support of Adults With Diabetes in Canada
The primary objective of this study is to examine the feasibility of a Facebook group-based program to support adults with diabetes in their foot self-care and prevention of foot ulcers. The sub-objectives are: 1.
- Trial name
- NCT04395521
- Testing
- Diabetic foot self-management support
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Helen Obilor
Lower Leg Wound
A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention
A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention
- Trial name
- WoundWand (NCT01924806)
- Testing
- WoundWand™ Debridement Device, Standard of Care sharp debridement
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 11 people
- Sponsor
- Smith & Nephew, Inc.
Diabetic Foot Ulcer (DFU), Diabetic Foot Ulcer Treatment
CHEMfoot: DEBRICHEM® in Chronic Diabetic Foot Wounds
This multicenter, randomized controlled trial will evaluate the effectiveness and safety of DEBRICHEM®, a topical desiccant gel, when added to standard care for chronic diabetic foot wounds.
- Conditions
- Diabetic Foot Ulcer (DFU), Diabetic Foot Ulcer Treatment, Diabetic Foot Wounds
- Trial name
- CHEMfoot (NCT07206862)
- Testing
- DEBRICHEM®
- Volunteers
- 242 people
- Sponsor
- DEBx Medical B.V.
Diabetic Foot, Lower Limb Ischemia
Stem Cell Therapy for Patients With Vascular Occlusive Diseases Such as Diabetic Foot
Mesenchymal stem cells with multidirectional differentiation potential,autologous stem cell transplantation into ischemic foot, make its differentiation to form new blood capillary, improve and restore the local blood flow.
- Trial name
- NCT02304588
- Testing
- Mesenchymal stem cells
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Diabetes Mellitus
Insulin Iontophoresis Mixed With Oleic Acid Versus Topical Insulin in Patients With Chronic Diabetic Foot Ulcer
This study will be conducted to investigate the effect of Insulin iontophoresis mixed with oleic acid versus topical insulin in patients with chronic diabetic foot ulcer
- Trial name
- NCT05444842
- Testing
- insulin iontophoresis, topical insulin, conventional treatment
- Volunteers
- 45 people
- Sponsor
- Cairo University
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