Clinical trials: Diabetic Feet
Diabetic Foot Ulcers, Hyperbaric Therapy
Hyperbaric Oxygen Therapy and Angiogenesis in Diabetic Patients With Foot Ulcers
Diabetic foot ulcers are a major cause of morbidity and mortality, accounting for approximately two-thirds of all non-traumatic amputations performed in the United States.
- Conditions
- Diabetic Foot Ulcers, Hyperbaric Therapy, Angiogenesis
- Trial name
- NCT00475202
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Abscess, Wound Infection
Comparison of Sequential IV/PO Moxifloxacin With IV Piperacillin/Tazobactam Followed by PO Amoxicillin/Clavulanic Acid in Patients With a Complicated Skin and Skin Structure Infection
Patients, who are considered suitable by their physicians to take part in this research, will have a physical examination (including an Electrocardiogram (ECG)), blood and urine samples taken, as well as a sample of the…
- Conditions
- Abscess, Wound Infection, Diabetic Foot, Ulcer
- Trial name
- NCT00402727
- Testing
- Moxifloxacin (Avelox, BAY12-8039), Piperacillin/Tazobactam & Amoxicillin/Clavulanic acid
- Where
- 123 sites in Austria, Belgium and 18 more
- Volunteers
- 813 people
- Sponsor
- Bayer
Diabetic Foot Ulcer
Prospective, Multicenter, RCT of the Tenex Ultrasound System
The goal of this multicenter randomized controlled trial is compare standard of care (SOC) to Tenex MicroTip ultrasound therapy plus SOC in patients with Wagner 1-2 diabetic foot ulcers.
- Trial name
- NCT06137222
- Testing
- Tenex TXB MicroTip Ultrasound system plus SOC, Standard of Care for diabetic foot ulcer
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Tenex Health Inc.
Diabetic Foot Ulcer
Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
The purpose of this clinical trial is to evaluate the safety and effectiveness of the treatment with the COMS One device in subjects with refractory diabetic foot ulcers (DFUs).
- Trial name
- Mavericks (NCT05758545)
- Testing
- COMS One device
- Where
- 30 sites in United States
- Volunteers
- 450 people
- Sponsor
- Piomic Medical
Diabetic Peripheral Neuropathy
IMX-150 Cream for Diabetic Neuropathy
The purpose of this study is to compare the effectiveness of two different dose of IMX-150 to that of placebo (non-active) in the treatment of diabetic peripheral neuropathy pain of the feet.
- Trial name
- NCT00641953
- Testing
- IMX-150
- Where
- 7 sites in United States
- Volunteers
- 155 people
- Sponsor
- Procris Pharmaceuticals
Diabetic Neuropathy
The Effect of Random Vibrations on Perception and Balance
The purpose of this study is to investigate the effects of vibrating insoles on vibration perception threshold (VPT) and balance of people with diabetic neuropathy.
- Trial name
- NCT02989831
- Testing
- Vibrating insoles 'on'
- Volunteers
- 40 people
- Sponsor
- University Medical Center Groningen
Diabetic Foot
BE Study of Metformin GSK 500mg
A randomized, balanced, open label, crossover, two period, two treatment, two sequence, single dose, oral bioequivalence study under fasting condition. It is a pivotal study.
- Trial name
- BA/BE 173/11 (NCT01710527)
- Testing
- Metformin 500mg, Glucophage 500mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Wound Heal
Impact of Cilostazol Versus Cilostazol and Selenium Combination on the Healing of Diabetic Foot Ulcer Patients
The growing incidence of DM can lead to the increased prevalence of diabetic foot complications, which have become a serious medical, social, and economic concern of global importance.
- Trial name
- NCT06117436
- Testing
- Cilostazol, Selenium
- Where
- Egypt
- Volunteers
- 206 people
- Sponsor
- Ain Shams University
Wound Infection Bacterial, Ulcer Foot
Wound Infection Detection Evaluation, WIDE
Chronic wounds, such as diabetic foot ulcers, place a huge burden on healthcare systems and can lead to complications with high morbidity, particularly if the wound if infected.
- Conditions
- Wound Infection Bacterial, Ulcer Foot, Diabetic Foot, Diagnostic Self Evaluation
- Trial name
- WIDE (NCT03883230)
- Testing
- GLYWD
- Where
- United Kingdom
- Volunteers
- 256 people
- Sponsor
- Cumbria Partnership NHS Foundation Trust
Diabetic Foot
Removable Walker for Neuropathic Ulcers
1. Objective: To evaluate the efficacy of removable cast walker compared to non-removable fiberglass off-bearing cast in the treatment of diabetic plantar foot ulcer 2.
- Trial name
- NCT01005264
- Testing
- non-removable fiberglass, Stabil-D®
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- IRCCS Multimedica
Diabetes Mellitus
The Effect of Message Framing in Diabetic Foot Self-Management
This study aims to assess how effective gain- and loss-framed messages are in improving diabetic foot care behaviors and increasing self-efficacy levels compared to routine foot care messages.
- Trial name
- NCT06813794
- Testing
- Gain- Framed Messages, Lost Framed Messages
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Ataturk University
Diabetic Foot Ulcer, Pressure Ulcer
A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1
The study is a prospective, single arm, multicenter efficacy study, consisting of 60 subjects who will complete the study (note: if any patients are lost to follow-up or withdrawn, enrollment will increase to compensate for loss…
- Conditions
- Diabetic Foot Ulcer, Pressure Ulcer, Venous Leg Ulcer, Trauma Injury
- Trial name
- NCT04577183
- Testing
- RD1 System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- RedDress Ltd.
Diabetic Foot Disease, Recurrence
Better Care Closer to Home: Enhancing Primary and Community Care
60 million people in Europe have diabetes (DM) and up to 34% (20.4 million) of them are at risk of developing diabetic foot ulcers (DFUs) in their lifetime (1).
- Trial name
- NCT07905664
- Testing
- Path Active™, a smart insole system designed to reduce the risk of plantar ulceration in patients with diabetic foot disease
- Where
- 3 sites in Canada, Denmark and 1 more
- Volunteers
- 84 people
- Sponsor
- Universidad Complutense de Madrid
Diabetic Foot Ulcer
Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers
The purpose of the following prospective, randomized, controlled clinical trial is to compare synthetic hybrid-scale fiber matrix (Restrata®, Acera Surgical, Inc.) with standard of care in treating diabetic foot ulcers in human…
- Trial name
- NCT04918784
- Testing
- Restrata®, Wound Dressing
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Acera Surgical, Inc.
Chronic Osteomyelitis, Fracture Related Infection
CERAMENT G Device Registry
This is an Observational Device Registry Study of CERAMENT|G in normal use in accordance with the IFU. It will run for a period of three years from enrolment of the first patient into the Study at each Site, before being subject…
- Conditions
- Chronic Osteomyelitis, Fracture Related Infection, Diabetic Foot Osteomyelitis
- Trial name
- NCT06010433
- Testing
- CERAMENT G
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- BONESUPPORT AB
Diabetes
Changes of Endothelial Function Before and After DSA in Patients With Diabetes
Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function.
- Trial name
- NCT01556984
- Testing
- DSA assay
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wuhan General Hospital of Guangzhou Military Command
Peripheral Arterial Disease, Diagnosis
DIAbetes Maximal ACCeleration
Prevalence of diabetes mellitus (DM) is increasing rapidly, with patient numbers projected to rise to 643 million by 2030. As a consequence of diabetes-related atherosclerosis, peripheral arterial disease (PAD) and in particular…
- Conditions
- Peripheral Arterial Disease, Diagnosis, Diabetic Foot
- Trial name
- DIAMACC (NCT05646147)
- Testing
- Maximal Systolic Acceleration
- Volunteers
- 238 people
- Sponsor
- Leiden University Medical Center
Chronic Diabetic Foot Ulcers
Study to Evaluate the Safety and Efficacy of CHAM* for the Treatment of Diabetic Foot Ulcers
A Multicenter, Randomized, Single-Blind Study with an Open-Label Extension Option to Further Evaluate the Safety and Efficacy of Cryopreserved Human Amniotic Membrane for the Treatment of Chronic Diabetic Foot Ulcers
- Trial name
- *OTI-15-01 (NCT02571738)
- Testing
- CHAM, Control
- Where
- 18 sites in United States
- Volunteers
- 108 people
- Sponsor
- Osiris Therapeutics
Diabetic Foot Ulcer
Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Wagner Grade 2 Foot Ulcers.
This is a phase III double-blind study to evaluate the efficacy and safety of ALLO-ASC-DFU in patients with Diabetic Wagner grade 2 Foot Ulcer, compared to placebo therapy.
- Trial name
- NCT04569409
- Testing
- ALLO-ASC-DFU, Vehicle Sheet
- Where
- 5 sites in South Korea
- Volunteers
- 104 people
- Sponsor
- Anterogen Co., Ltd.
Chronic Wound, Burn Wound
Wound Healing Endpoint and Recurrence
This study is a continuation of a previously approved protocol conducted at Ohio State University and Indiana University. The first two aims of the original protocol have been completed, and this protocol will finish enrollment…
- Conditions
- Chronic Wound, Burn Wound, Diabetic Foot Ulcers, Pressure Ulcers
- Trial name
- NCT02577120
- Testing
- Epiceram Skin Barrier Function, Vaseline Petroleum Jelly
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Sashwati Roy
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