Clinical trials: Diabetic Gastroparesis
Gastroparesis Postoperative, Gastroparesis Due to Diabetes Mellitus
Gastric Per Oral Endoscopic Myotomy (G-POEM) in Refractory Gastroparesis
Refractory gastroparesis is a disease characterized by a delayed gastric emptying without a mechanical obstruction. Actual treatments have a limited efficacy and gastric per-oral endoscopic myotomy (G-POEM) is a new treatment…
- Conditions
- Gastroparesis Postoperative, Gastroparesis Due to Diabetes Mellitus, Idiopathic Gastric Stasis
- Trial name
- G-POEM (NCT03126513)
- Testing
- G-POEM
- Where
- Mexico
- Volunteers
- 82 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Diabetes Mellitus, Diabetes Mellitus Complications
Phase 2 Study to Evaluate Safety & Efficacy of RM-131 Administered to Patients With Diabetic Gastroparesis
The purpose of this study is to evaluate the effects of RM-131 on gastric emptying, gastroparesis symptoms, and the safety and tolerability of RM-131 compared to placebo in patients with Type 1 and Type 2 diabetes mellitus and…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus Complications, Gastroparesis
- Trial name
- NCT01571297
- Testing
- RM-131
- Where
- 30 sites in United States
- Volunteers
- 204 people
- Sponsor
- Motus Therapeutics, Inc.
Diabetes Mellitus, Gastroparesis With Diabetes Mellitus
Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes
This study will assess changes in glycemic control in 40 patients with diabetes who undergo per-oral pyloromyotomy (POP) for medically refractory gastroparesis.
- Conditions
- Diabetes Mellitus, Gastroparesis With Diabetes Mellitus, Gastroparesis
- Trial name
- NCT04696159
- Testing
- Pyloromyotomy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Matthew Allemang
Gastroparesis, Diabetic Gastroparesis
Gastroparesis Registry 3
The purpose of this study is to create a new registry of patients with gastroparesis in order to better understand the characteristics of patients with gastroparesis and follow how their condition changes over time.
- Conditions
- Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis
- Trial name
- GpR3 (NCT03680859)
- Where
- 6 sites in United States
- Volunteers
- 406 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gastroparesis, Gastroparesis Postoperative
Safety and Efficacy of GPOEM in the Treatment of Gastroparesis
The purpose of this study is to assess the clinical efficacy and safety in the treatment of gastroparesis.
- Conditions
- Gastroparesis, Gastroparesis Postoperative, Gastroparesis With Diabetes Mellitus
- Trial name
- NCT04349670
- Testing
- GPOEM - gastric per-oral endoscopic myotomy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS San Raffaele
Gastroparesis, Diabetic Gastroparesis
Gastroparesis Registry 2
To expand a registry of patients for the study of the epidemiology, etiology, and degree of morbidity associated with gastroparesis.
- Conditions
- Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis
- Trial name
- GpR2 (NCT01696747)
- Where
- 6 sites in United States
- Volunteers
- 506 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabetic Gastroparesis
Thoracic Splanchnic Magnetic Neuromodulation Therapy (ThorS-MagNT) for Grade 3 Diabetic Gastroparesis: Pilot Study
Diabetic gastroparesis (DG) is an under recognized and significant complication of diabetes with lack of effective treatments. Recently, a 4-fold increase in hospitalizations has been seen in DG patients with refractory symptoms…
- Trial name
- ThorS-MagNT (NCT04706832)
- Testing
- Thoracic Splanchnic Magnetic Neuromodulation Therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Augusta University
Diabetic Gastroparesis
Effect of Virtual Yoga in Diabetic Gastroparesis Patients
The purpose of this study is to investigate the potential benefits of an online yoga module for patients with gastroparesis. Specifically, the study aims to: 1.
- Trial name
- NCT07717554
- Testing
- Virtual Yoga
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Ohio State University
Diabetic Gastroparesis
Study of Promethazine for Treatment of Diabetic Gastroparesis
Adult diabetic patients (ages 18-65) with gastric emptying scintigraphy-confirmed delayed gastric emptying will be recruited to participate in the study.
- Trial name
- NCT02130622
- Testing
- Promethazine, Sugar pill
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Type 1 Diabetes, Gastroparesis Due to Diabetes Mellitus Type I
To Study the Efficacy and Safety of Medtronic 780G Insulin Pump in People With Gastroparesis and Type 1 Diabetes.
The goal of this clinical trial is to evaluate the efficacy and safety of Medtronic 780G automated insulin delivery system in adult persons with type 1 diabetes and gastroparesis.
- Trial name
- NCT07287943
- Testing
- Medtronic 780G AID
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Viral N. Shah
Idiopathic Gastroparesis, Diabetic Gastroparesis
Intraluminal Endosonography for Examination of the Structural Changes of the Stomach in Gastroparetic Patients
Patients who empty their stomach slowly may have what we call "Slow gastric emptying" or "gastroparesis". These patients can have some changes in the thickness of their stomach wall.
- Trial name
- NCT01916460
- Testing
- Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis
Biomagnetic Characterization of Gastric Dysrhythmias III
There is a tremendous clinical need for a noninvasive technique that can assess gastric electrical activity and would be repeatable without any exposure to radiation.
- Conditions
- Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis, Total or Partial Gastrectomy
- Trial name
- NCT03176927
- Testing
- magnetogastrogram
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Continuous Glucose Metrics in Patients With Gastroparesis in Type 1 or Type 2 Diabetes
A pilot study to evaluate and compare glucose metrics using a real-time continuous glucose monitor (FreeStyle Libre 3 sensor) between patients with diabetes and gastroparesis and those with diabetes without gastroparesis.
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Gastroparesis With Diabetes Mellitus
- Trial name
- NCT06046833
- Testing
- FreeStyle Libre 3 continuous glucose monitoring sensor, Nutritional drink
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Samita Garg
Diabetes Mellitus, Type 1, Gastroparesis
The Effect of Gluten-free Diet in Type 1 Diabetics With Dyspepsia Symptoms
Patients with type-1 diabetes are more susceptible to motility-related upper gastrointestinal symptoms. Dietary interventions are one of the treatment pillars for these symptoms.
- Conditions
- Diabetes Mellitus, Type 1, Gastroparesis, Dyspepsia, Gluten Sensitivity
- Trial name
- NCT03089632
- Testing
- Gluten-free diet
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Diabetic Gastroparesis
The Effect of Acupuncture on Symptoms, Gastric Emptying Rate and Glucose Control in Patients With Diabetic Gastroparesis
Diabetes affects 5.8% of the adult population in Israel (1). Gastroparesis is a syndrome characterized by delayed gastric emptying in the absence of mechanical obstruction of the stomach.Treatment with acupuncture has been…
- Trial name
- NCT00874133
- Testing
- Acupuncture, Motilium
- Volunteers
- 8 people
- Sponsor
- Rabin Medical Center
Diabetic Gastroparesis
Gastroparesis in type2 Diabetic Patient
Gastroparesis is defined by objective delaying of gastric emptying without any evidence of mechanical obstruction. Diabetic gastroparesis is a potential complication that occurs in the setting of poorly controlled diabetes…
- Trial name
- NCT05584462
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gastroparesis, Gastroparesis Nondiabetic
Gastroparesis Registry 4
The Gastroparesis Registry 4 (GpR4) is an observational study of patients with symptoms of gastroparesis (Gp) and functional dyspepsia (FD) with either delayed or normal gastric emptying.
- Conditions
- Gastroparesis, Gastroparesis Nondiabetic, Gastroparesis Due to Diabetes Mellitus Type I, Gastroparesis Due to Diabetes Mellitus Type II
- Trial name
- GpR4 (NCT05846802)
- Where
- 6 sites in United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabetic Gastroparesis
Docusate/Senna for the Treatment of Diabetic Gastroparesis
The aim of the study is to evaluate the efficacy of the stimulant laxative Senokot-S® for the treatment of diabetic gastroparesis.
- Trial name
- NCT03342157
- Testing
- senna/docusate
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Wake Forest University Health Sciences
Gastroparesis, Idiopathic Gastric Motility Disorder
Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms
The overall objective of this study is to determine if there are pyloric sphincter abnormalities in patients with gastroparesis symptoms and determine how prevalent these abnormalities are using tests to assess the pyloric…
- Conditions
- Gastroparesis, Idiopathic Gastric Motility Disorder, Diabetic Gastroparesis
- Trial name
- PSAGS (NCT04661215)
- Where
- 5 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gastroparesis Due to Diabetes Mellitus Type I
Pathophysiology of Diabetic Gastroparesis
The goal of this study is to explore the pathophysiology of diabetic gastroparesis by conducting an exploratory cohort study. Participants will be type 1 diabetes patients with and without gastroparesis.
- Trial name
- PATODIAG (NCT05717205)
- Testing
- technetium scitigraphy
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Hvidovre University Hospital