Clinical trials: Diabetic Ketoacidosis
Metabolic Acidosis, Diabetic Ketoacidosis
Diabetic Ketoacidosis Diagnosis and Management
This is the first and only study conducted on the use of capnography in children diagnosed with DKA to evaluate the initial clinical grading of DKA, monitor clinical improvement, and predict complications such as brain edema.
- Conditions
- Metabolic Acidosis, Diabetic Ketoacidosis, Brain Edema
- Trial name
- NCT06327737
- Testing
- Capnography
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Akdeniz University
Diabetes
Fluid Resuscitation for Pediatric Diabetic Ketoacidosis
Randomized trial to determine if the volume of fluid administration in pediatric patients with DKA impacts the rate of normalization of serum bicarbonate, pH as well as the length of treatment
- Trial name
- NCT01701557
- Testing
- slow fluid rate, fast fluid rate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Sepsis, Acute Renal Failure
Inferior Vena Cava Collapsibility and Distensibility Assessment in Critical Care.
This study will help in determining the impact of assessment of Inferior Vena Cava Collapsibility and Distensibility Index (IVC CI and DI) through Point Of Care Ultra Sound (POCUS), for the fluid management of critically ill…
- Conditions
- Sepsis, Acute Renal Failure, Acute Gastroenteritis, Diabetic Ketoacidosis
- Trial name
- NCT06516692
- Testing
- Inferior Vena Cava Collapsibility/distensibility Index (IVC CI/DI) assessment
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Diabetes Mellitus, Type 2, Urosepsis
Safety of Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors Among Patients With Type 2 Diabetes
The purpose of this study is to compare the risk of serious adverse events associated with the use of sodium-glucose cotransporter 2 (SGLT2) inhibitors in comparison with the use of dipeptidyl peptidase-4 (DPP-4) inhibitors among…
- Conditions
- Diabetes Mellitus, Type 2, Urosepsis, Diabetic Ketoacidosis, Lower Extremity Amputation
- Trial name
- NCT04017221
- Testing
- Sodium-glucose cotransporter 2 (SGLT2) inhibitors, Dipeptidyl peptidase-4 (DPP-4) inhibitors, Other treatment combinations
- Where
- Canada
- Volunteers
- 1,249,636 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
Diabetic Keto-acidosis
Fluid Administration in Ketoacidosis (DRINK)
Management of severe diabetic ketoacidosis is based on insulin therapy, correction of metabolic disorders and fluid resuscitation.
- Trial name
- DRINK (NCT06541535)
- Testing
- Fluid resuscitation with isotonic saline only, Fluid resuscitation with Ringer Lactate
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Type 1 Diabetes Mellitus, Diabetic Ketoacidosis
Metabolic Effects of Exogenous 3-hydroxybutyrate in Patients With Type 1 Diabetes and Healthy Controls
The main objective of this clinical trial is to study the metabolic effects of intravenous infusion of the ketone body, 3-hydroxybutyrate (3-OHB), in patients with type 1 diabetes and healthy control subjects.
- Trial name
- NCT04656236
- Testing
- 3-hydroxybutyrate
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus