Clinical trials: Diabetic Mellitus
Type 2 Diabetes
Blood Glucose Response to Highly Viscous Polysaccharide Enriched Biscuits in Healthy and Diabetic Subjects
Our objective was to test whether the highly viscous polysaccharide incorporated into the biscuit formulation would reduce the postprandial blood glucose response equally in healthy subjects and individuals with type 2 diabetes.
- Trial name
- NCT00728143
- Testing
- Highly viscous polysaccharide enriched biscuits
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Type 2 Diabetes, Diabetic Peripheral Neuropathy
Effects of Whole-body Vibration Therapy on Type 2 Diabetic Patients with and Without Polyneuropathy
The aim of this study is to show how whole body vibration training practiced for 12 weeks affects the levels of inflammatory biomarkers such as C reactive protein (CRP) and, interleukin-6 (IL-6), in Type 2 diabetic patients…
- Conditions
- Type 2 Diabetes, Diabetic Peripheral Neuropathy, Exercise
- Trial name
- NCT06033508
- Testing
- exercise with whole body vibration device
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Diabetic Foot Ulcer
RESPOND Restoring Equilibrium and Wound Stimulation to Promote Healing Of Non-healing DFUs
To evaluate the safety and effectiveness of MIST Therapy in conjunction with Standard of Care (SOC) compared to Standard of Care alone in the treatment of diabetic foot ulcers (DFU).
- Trial name
- NCT01608776
- Testing
- MIST Therapy, SOC - Standard of Care
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Celleration, Inc.
Diabetes Mellitus, Type 2
Efficacy and Safety of BI 1356 (Linagliptin) Versus Placebo in Type 2 Diabetic Patients With Insufficient Glycemic Control
To investigate efficacy, safety and tolerability of BI 1356 versus placebo
- Trial name
- NCT00621140
- Testing
- linagliptin
- Where
- 69 sites in Croatia, India and 9 more
- Volunteers
- 503 people
- Sponsor
- Boehringer Ingelheim
Diabetes, Diabetic Nephropathy
The Family Investigation of Nephropathy and Diabetes Study
The Family Investigation of Nephropathy and Diabetes (FIND)Study is a multi-center consortium. The charge of the consortium is to acquire sets of families with well-characterized diabetic nephropathy, establish a secure master…
- Trial name
- FIND (NCT00301249)
- Where
- 5 sites in United States
- Volunteers
- 9,031 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetic Foot Ulcer
Exercise Enhances Wound Healing in Patients With Diabetic Foot Ulcers
The overarching purpose of this study is to investigate the impact that exercise, as delivered through a medically supervised, outpatient cardiac rehabilitation program, has on the wound healing process in Type 2 diabetics having…
- Trial name
- NCT04791449
- Testing
- Structured exercise program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Diabetic Foot Ulcer, Diabetes Mellitus
Total Contact Soft Cast in Diabetic Foot Ulcers
To determine the effectiveness, compliance, patient tolerance, ease of use and safety of total contact soft cast in diabetic foot ulcers.
- Conditions
- Diabetic Foot Ulcer, Diabetes Mellitus, Foot Ulcer, Foot Ulcer, Diabetic
- Trial name
- NCT04210089
- Testing
- Total Contact Soft Cast, Cam Boot
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Minnesota
Pregnancy in Diabetic
Incidence of Hypoglycemia in Pregnant Ladies With or Without Gestational Diabetes Fasting Ramadan
The physiological change in food and sleep pattern during Ramadan impacted hypoglycemia risks among pregnant women. Few studies investigated the incidence of hypoglycemia pregnant women with or without diabetes during fasting in…
- Trial name
- NCT04862390
- Testing
- Continuous glucose monitoring
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Abdullah International Medical Research Center
Stargardt Disease, Diabetic Retinopathy
Oxidative Stress In Stargardt Disease, Age Related Macular Degeneration and Diabetic Retinopathy
In this study, markers of oxidative stress will be measured in the aqueous humour of stargardt disease, age related macular degeneration and diabetic retinopathy patients compared to controls.
- Conditions
- Stargardt Disease, Diabetic Retinopathy, Macular Degeneration (Age Related)
- Trial name
- NCT02875704
- Testing
- Anterior Chamber (AC) Tap
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Johns Hopkins University
Diabetic Polyneuropathy, Diabetic Foot Ulcer
TempTouch IR Thermometry & Diabetic Patient Self-Care
Foot ulcers develop in diabetics with neuropathy because of cumulative injury over the course of several days. These patients do not feel pain, and do not recognize their foot is being injured until a wound develops.
- Conditions
- Diabetic Polyneuropathy, Diabetic Foot Ulcer, Diabetes, Foot Infection
- Trial name
- NCT00289497
- Testing
- TempTouch®
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- Diabetica Solutions Inc.
Type 2 Diabetes
Effect of Rotating Magnetic Therapy on Blood Glucose Spectrum of Type 2 Diabetic Patients With Glargine Therapy
The aim of the study is to assess the effect of Rotating Magnetic Therapy on blood glucose spectrum of type 2 diabetic patients with glargine therapy using flash glucose monitors
- Trial name
- NCT03983187
- Testing
- Rotating Magnetic Therapy
- Volunteers
- 200 people
- Sponsor
- Majianhua
Prediabetes
Mitochondrial-related Platelet Transcript Expression Levels in Pre-diabetic Subjects Randomized to Metformin or Placebo
Diabetes mellitus (DM) imposes an approximate 2-fold increased risk of atherothrombosis. Patients with type 2 DM have a 2- to 4-fold increase in the risk of coronary artery disease (CAD) and atherothrombotic complications.
- Trial name
- MAP-2 (NCT02682121)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Utah
Diabetes Mellitus Type 2
A Clinical Trial Assessing The Impact Of Inhaled Insulin On Glucose Control In Patients With Type 2 Diabetes Mellitus
To assess the impact on glucose control by inhaled insulin in patients with type 2 diabetes who are not well controlled on 2 or more oral anti-diabetic agents
- Trial name
- NCT00282971
- Testing
- Inhaled Insulin (Exubera), Standard of Care
- Where
- 64 sites in Canada, France and 5 more
- Volunteers
- 354 people
- Sponsor
- Pfizer
Wound Heal, Diabetic Foot Ulcer
Effect of Topical Ozone on The Healing Diabetic Foot Ulcer
Despite conflicting and contradictory evidence regarding its efficacy, some wound care centres have advocated and adopted ozone for treating DFU. However, there are gaps in the application of topical ozone therapy.
- Conditions
- Wound Heal, Diabetic Foot Ulcer, Ozone
- Trial name
- NCT05977309
- Testing
- Topical ozone therapy
- Where
- Indonesia
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Asmat Burhan
Type 2 Diabetes Mellitus in Obese
Dietary Intake, Eating Behavior, Physical Activity Level and Their Relationships With Glycemic and Weight Control in Hong Kong Chinese Type 2 Diabetic Patients
The objective of this study is to describe and examine the dietary intake, eating behavior and physical activity level of a cohort of Hong Kong Chinese with T2DM and their association with weight and glycemic control at baseline…
- Trial name
- NCT02937987
- Volunteers
- 211 people
- Sponsor
- Chinese University of Hong Kong
Diabetes Mellitus, Type 2, Diabetic Retinopathy
Exploring the Effectiveness of AI Generative Models for Diabetic Patients
We plan to explore the usability of Generative AI-Chatbot for Diabetic Patient
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Retinopathy, Diabetes
- Trial name
- NCT05883072
- Testing
- Exploring AI-Chatbot
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- Pakistan Council of Scientific and Industrial Research
Macular Edema
A Study to Evaluate the Effectiveness of Intravitreal Aflibercept in Patients With Diabetic Macular Edema and/or Macular Edema Secondary to Retinal Vein Occlusion, Which Either Have or Have Not Been Pretreated for Their Disease
AURIGA is designed to collect data from routine clinical practice on the effectiveness and utilization of intravitreal aflibercept in the treatment of visual impairment due to diabetic macular edema (DME) or macula edema…
- Trial name
- AURIGA (NCT03161912)
- Testing
- Aflibercept (Eylea, BAY86-5321)
- Where
- 11 sites in China, Egypt and 9 more
- Volunteers
- 2,481 people
- Sponsor
- Bayer
Diabetes Complications
Pyridostigmine and Its Effects on Autonomic Modulation in Diabetic Patients
The purpose of the study is to determine if pyridostigmine bromide improves heart rate variability of type 2 diabetes mellitus subjects with cardiovascular autonomic neuropathy.
- Trial name
- NCT00953914
- Testing
- Pyridostigmine
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome
Among adult individuals with type 2 diabetes mellitus and at risk for heart failure with impaired relaxation of the heart mildly reduced kidney filtration function (Type 4 cardiorenal syndrome) this trial will evaluate the…
- Conditions
- Type 2 Diabetes Mellitus, Chronic Kidney Disease, Left Ventricular Diastolic Dysfunction
- Trial name
- NCT02251431
- Testing
- BYDUREON
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Baylor Research Institute
Nephropathy, Diabetic Nephropathies
Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose-coTransporter Inhibitors Avoiding Kidney hypOxia
Background: Sodium-glucose-cotransporter (SGLT) inhibition has been observed to reduce risk of cardiovascular events and kidney failure in persons with type 2 diabetes.
- Conditions
- Nephropathy, Diabetic Nephropathies, Diabetes Mellitus, Type 1, Albuminuria
- Trial name
- PLUTO (NCT06147232)
- Testing
- Sotagliflozin
- Where
- 2 sites in Denmark, United Kingdom
- Volunteers
- 69 people
- Sponsor
- Steno Diabetes Center Copenhagen