Clinical trials: Diabetic Neuralgia
Diabetic Peripheral Neuropathy
Efficacy and Safety of CNV2197944 Versus Placebo in Patients With Diabetic Peripheral Neuropathy
To investigate the effect of repeat oral dosing of CNV2197944 75 mg tid on the pain experienced in diabetic peripheral neuropathy (DPN) as measured by changes in PI-NRS after three weeks of treatment compared to the baseline…
- Trial name
- NCT01893125
- Testing
- CNV2197944
- Where
- Hungary
- Volunteers
- 126 people
- Sponsor
- Convergence Pharmaceuticals
Diabetic Neuropathy, Chemotherapy Induced Neuropathy
A Clinical Outcomes Study to Measure Reduction in Pain and Numbness During Administration of an Amino Acid Formulation in Subjects Diagnosed With Peripheral Neuropathy
A clinical outcomes study measuring reduction in pain and numbness experienced in four types of peripheral neuropathy patients during 60 day administration of the an amino acid formulation.
- Conditions
- Diabetic Neuropathy, Chemotherapy Induced Neuropathy, HIV Neuropathy, Trauma Induced Neuropathy
- Trial name
- Neuron012703 (NCT01537705)
- Testing
- Neuron012703 (Medical Food)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Targeted Medical Pharma
Diabetic Neuropathies
Safety Study of TAK-128 in Subjects With Diabetic Peripheral Neuropathy
The purpose of this study is to determine the safety of TAK-128, once daily (QD), for treatment of diabetic peripheral neuropathy
- Trial name
- NCT00756041
- Testing
- TAK-128
- Volunteers
- 221 people
- Sponsor
- Takeda
Diabetic Neuropathy, Painful
Perineural Injections of Incobotulinumtoxin-A for Diabetic Neuropathic Pain of the Lower Extremities
The goal of this clinical trial is to test perineural injections (injections around a nerve) of incobotulinumtoxin-A in participants with diabetic nerve pain of the feet and lower legs.
- Trial name
- PINBOT (NCT05623111)
- Testing
- Incobotulinumtoxin-A 100 UNIT Injection, Saline
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetic Neuropathic Pain
A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain
People with diabetes can, over time develop nerve damage throughout the body with symptoms such as pain, tingling, or numbness (loss of feeling) in the hands, arms, feet and legs.
- Trial name
- NCT01345045
- Testing
- ABT-639, pregabalin
- Where
- 35 sites in United States, Czechia and 3 more
- Volunteers
- 193 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Painful Diabetic Neuropathy
Efficacy and Safety Study of ARC-4558 for Management of Pain Associated With Painful Diabetic Neuropathy
The purpose of this study is to determine whether ARC-4558 is effective in managing pain associated with painful diabetic neuropathy.
- Trial name
- NCT00695565
- Testing
- Clonidine Topical Gel (ARC-4558)
- Where
- 16 sites in United States
- Volunteers
- 180 people
- Sponsor
- Arcion Therapeutics Inc
Diabetic Polyneuropathy, Diabetic Neuralgia
A Study of Phyllanthus Niruri and Sida Cordifolia in Diabetic Peripheral Polyneuropathy
The purpose of the study is to determine whether phyllanthus niruri and sida cordifolia are effective in treatment of diabetic polyneuropathy compared to placebo.
- Conditions
- Diabetic Polyneuropathy, Diabetic Neuralgia, Diabetic Neuropathies, Diabetic Neuropathy
- Trial name
- VEDICINE (NCT02107469)
- Testing
- Sida cordifolia roots, Phyllanthus niruri, Sida cordifolia roots extract
- Where
- India
- Volunteers
- 98 people
- Sponsor
- Rosenberg European Academy of Ayurveda
Diabetic Neuropathic Pain
the Effectiveness of Intermittent Pneumatic Compression on Neuropathic Pain in Patients With Diabetic Polyneuropathy
In this study,the effectiveness of intermittent pneumatic compression therapy on neuropathic pain and quality of life in patients with neuropathic pain due to type 2 diabetes was investigated
- Trial name
- NCT06336486
- Testing
- intermittent pneumatic compression +pregabalin group, pregabalin group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Busra Gunes
Diabetic Neuropathy
An Open Label, Dose Finding Trial of Viagra for the Treatment of Neuropathic Pain (in Diabetes Mellitus)
The purpose of this study is to study if sildenafil (Viagra) is effective in improving neuropathic pain. This will be an open label study at 3 doses of sildenafil (25 mg, 50 mg and 100 mg).
- Trial name
- NCT00194909
- Testing
- sildenafil (Viagra)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Weill Medical College of Cornell University
Diabetic Neuropathies, Pain
Functional Imaging of the Therapeutic Effect of Pregabalin in Treatment for Neuropathic Pain
Functional Imaging of the therapeutic effect of Pregabalin in treatment for neuropathic pain in patients with Diabetic Polyneuropathy using proton Magnetic Resonance Spectroscopy (MRS): The aim of our study is to investigate the…
- Trial name
- NCT01180608
- Testing
- MR Spectroscopy
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Painful Diabetic Neuropathy
Eslicarbazepine Acetate as Therapy in Diabetic Neuropathic Pain
The primary objective of this study is to assess the efficacy of Eslicarbazepine acetate (ESL) as therapy in subjects with Diabetic Neuropathic Pain (DNP) over a 15 week treatment phase.
- Trial name
- NCT01129960
- Testing
- Eslicarbazepine acetate (BIA 2-093)
- Where
- Portugal
- Volunteers
- 332 people
- Sponsor
- Bial - Portela C S.A.
Diabetic Peripheral Neuropathic Pain
A Study of Duloxetine (LY248686) in Participants With Diabetic Peripheral Neuropathic Pain (DPNP)
The main purpose of this study is to evaluate the effectiveness and safety of the study drug known as duloxetine in participants with diabetic peripheral neuropathic pain.
- Trial name
- NCT02417935
- Testing
- Duloxetine, Pregabalin
- Volunteers
- 304 people
- Sponsor
- Eli Lilly and Company
Painful Diabetic Neuropathy
EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA
The purpose of this study is to investigate the safety and efficacy of the current hard gelatin capsule formulation of NRD135S.E1 80 mg once daily in the treatment of PDPN when administered for 13 weeks.
- Trial name
- EN21-01 (NCT05480228)
- Testing
- NRD135SE.1
- Where
- 26 sites in United States
- Volunteers
- 127 people
- Sponsor
- James P. Rathmell, MD
Diabetic Peripheral Neuropathic Pain (DPN)
Effect of Trimetazidine on Endothelin-1 and Clinical Outcomes of Patients With Diabetic Peripheral Neuropathy
The goal of this clinical trial is to investigate if trimetazidine can improve clinical outcomes of patients with diabetic peripheral neuropathy.
- Trial name
- NCT07794475
- Testing
- Trimetazidine Dihydrochloride Tablets
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sara Refaat Azab Metry
Healthy
Bioequivalence Study of Two Formulations of Pregabalin CR (Controlled-release) Table 150 mg
The purpose of this clinical trial is to (1) evaluate the bioequivalence(BE) of GLA5PR GLARS-NF3 tablet 150mg administered regular diet relative to GLA5PR GLARS-NF1 tablet 150mg administered regular diet and (2) determine the…
- Trial name
- NCT02955472
- Testing
- GLA5PR GLARS-NF3 tablet 150mg, GLA5PR GLARS-NF1 tablet 150mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Diabetic Polyneuropathy, Postherpetic Neuralgia
Efficacy, Safety, Tolerability and Pharmacokinetics of Concomitant Administration of Tramadol With Duloxetine or Pregabalin
Tramadol is an opioid analgesic, which is widely used in the treatment of acute and neuropathic pain. Treatment of neuropathic pain often requires a combination of pain medications due to the complex nature of neuropathic pain…
- Trial name
- NCT01116531
- Testing
- Tramadol, Duloxetine, Pregabalin
- Where
- Finland
- Sponsor
- Turku University Hospital
Diabetic Neuropathy
Understanding Risk Factors and Determinants for Neuropathic Pain
Understanding risk factors and determinants for neuropathic pain.
- Trial name
- Neuropathic (NCT02402361)
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rambam Health Care Campus
Diabetic Neuropathy
Vitamin D Treatment for Painful Diabetic Neuropathy
The main objective of the study is to assess the effect of vitamin D treatment on painful diabetic neuropathy in Pakistan. This is a prospective study of diabetic patients with a DN score ≥ 4, administered a single dose of…
- Trial name
- NCT02737423
- Testing
- cholecalciferol
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Baqai Institute of Diabetology and Endocrinology
Diabetic Neuropathies, Pain
The Effects of the Magnetic Molecular Energizer (MME) on Diabetic Peripheral Neuropathy
This study is intended to demonstrate that exposure to a high intensity, DC electromagnetic field, as supplied by the investigational device known as the Molecular Magnetic Energizer (MME), will create a clinically meaningful…
- Conditions
- Diabetic Neuropathies, Pain, Neuralgia
- Trial name
- NCT00134524
- Testing
- MME procedure
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- Advanced Magnetic Research Institute International
Diabetic Foot
A Sympathetic Ganglion, High-voltage Pulsed Radiofrequency Ablation of Peripheral Neuralgia
The Sham Operation Group was used as control, the patients were assessed with the Digital Rating Scale (NRS) , the quality of life-related scale (Euro Qol) , clinical outcome measures: physician's overall impression of changes in…
- Trial name
- NCT05831059
- Testing
- Pulsed radio frequency therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine