Clinical trials: Diabetic Neuropathy, Painful
Diabetic Foot, Plantar Fasciitis
Joints Mobilization Versus Myofascial Release on Diabetic Patients With Painful Heel
Diabetes mellitus (DM) increases stiffness and thickness of foot structures. This may alter the foot's biomechanics and increase plantar pressure distribution, mainly on the forefoot region.
- Trial name
- NCT03851848
- Testing
- Joint mobilization (JM), Myofascial release (MFR)
- Where
- Saudi Arabia
- Volunteers
- 46 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Carpal Tunnel Syndrome, Entrapment Neuropathies
Nerve Entrapment in Diabetic Patients
The aim of this study is in a prospective, consecutive series of diabetic patients with carpal tunnel syndrome, who are then age and gender matched with non-diabetic patients having idiopathic carpal tunnel syndrome to compare…
- Conditions
- Carpal Tunnel Syndrome, Entrapment Neuropathies, Nerve Compression Syndromes, Diabetes Complications
- Trial name
- NCT00775333
- Testing
- Outcome after carpal tunnel release
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Skane University Hospital
Diabetic Neuropathy
A Trial to Assess the Efficacy and Safety of SPM 927 (Lacosamide) in Subjects With Painful Distal Diabetic Neuropathy
This trial was conducted at about 50 sites in Europe and has been clinically completed. Patients had symptoms of painful diabetic neuropathy for 6 months up to 5 years with an optimized diabetic control and at least moderate…
- Trial name
- NCT00238524
- Testing
- SPM 927
- Where
- Germany
- Volunteers
- 357 people
- Sponsor
- UCB Pharma
Diabetic Polyneuropathy
Efficacy and Safety Study of Topical Capsaicin in Painful Diabetic Neuropathy
Painful diabetic neuropathy is the most common cause of neuropathic pain. 0.075% topical capsaicin has been used to treat the pain, but there is no data in lower concentration.
- Trial name
- NCT00993070
- Testing
- Capsaicin
- Where
- Thailand
- Volunteers
- 33 people
- Sponsor
- Thammasat University
Painful Diabetic Neuropathy, Diabetes
A Safety Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Painful Diabetic Neuropathy
Study CLO-311 is a multicenter, open-label, single-arm study to assess the long-term use of Clonidine Gel in the treatment of pain associated with PDN.
- Trial name
- NCT02355158
- Testing
- clonidine hydrochloride topical gel, 0.1%
- Where
- 20 sites in United States
- Volunteers
- 197 people
- Sponsor
- BioDelivery Sciences International
Painful Peripheral Diabetic Neuropathy
Nociceptive Pain Fiber Response
This study is designed to evaluate the effectiveness of the Provant Therapy System in improving localized nerve growth and skin perfusion in subjects with painful peripheral diabetic neuropathy of the foot.
- Trial name
- NCT02696070
- Testing
- Provant Therapy System
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Regenesis Biomedical, Inc.
Diabetes
Lidoderm® (Lidocaine Patch 5%) in Diabetic and Idiopathic Neuropathy
Patients with Type I or II diabetes and painful distal symmetric sensorimotor polyneuropathy with dynamic allodynia of the lower extremities, patients with Type I or II diabetes and pain distal symmetric sensorimotor…
- Trial name
- NCT00903851
- Testing
- Lidoderm
- Where
- 4 sites in United States
- Volunteers
- 76 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Diabetic Peripheral Neuropathy
Topical Menthol +/- Mannitol for Painful Diabetic Peripheral Neuropathy
Treatments for painful diabetic peripheral neuropathy (PDPN) are not very effective and have multiple side effects. To find out if a menthol cream alone or with added mannitol treats PDPN effectively, 90 participants with PDPN…
- Trial name
- NCT02728687
- Testing
- Mannitol, Menthol
- Where
- 5 sites in Canada
- Volunteers
- 72 people
- Sponsor
- University of British Columbia
Neuropathic Pain
Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults
The goal of this clinical trial is to learn if ASCT-83 is safe and well-tolerated and measure how ASCT-83 is absorbed, distributed, and eliminated from the body over time. The study will be conducted in healthy adults.
- Trial name
- NCT07363395
- Testing
- ASCT-83
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Alcamena Stem Cell Therapeutics
Peripheral Diabetic Neuropathy
0.075% Capsaicin Lotion for the Treatment of Painful Diabetic Neuropathy
To study that 0.075% capsaicin lotion is safe, well tolerated and provide significant pain relief in patients with PDN compared with placebo lotion as a randomized, double- Blind, crossover, placebo-controlled trial
- Trial name
- NCT03113448
- Testing
- 0.075% Capsaicin Lotion
- Where
- Thailand
- Volunteers
- 42 people
- Sponsor
- Thammasat University
Neuralgia, Neuralgia; Postherpetic
Evaluation of an Effectiveness and Safety of the Electroacupuncture in the Management of Intractable Neuropathic Pain
The investigators will evaluate the effectiveness and safety of acupuncture treatment in refractory neuropathic pain patients.
- Conditions
- Neuralgia, Neuralgia; Postherpetic, Diabetic Neuropathy, Painful, Failed Back Surgery Syndrome
- Trial name
- NCT03315598
- Testing
- Electroacupuncture
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Pain, Diabetic Peripheral Neuropathy
Asian Phase 2 Study for Treatment of Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to investigate the effectiveness and safety of DS-5565, compared to placebo, in subjects with pain associated with diabetic peripheral neuropathy.
- Trial name
- NCT01504412
- Testing
- DS-5565, Pregabalin capsules
- Where
- 3 sites in Japan, South Korea and 1 more
- Volunteers
- 450 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Neuropathy, Painful Diabetic
Neurofeedback for the Management of Neuropathic Pain in People With Diabetes
We will conduct a high-quality, blinded, randomized controlled trial (RCT) to rigorously test the effectiveness of EEG-based NF in patients with diabetes-related neuropathic pain.
- Trial name
- NCT06603792
- Testing
- EEG-neurofeedback
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Painful Peripheral Diabetic Neuropathy
A Study to Evaluate PEMF Therapy on Experimentally Inducted Pain in Subjects With Painful Peripheral Diabetic Neuropathy
Evaluate the effectiveness of the Provant Therapy System compared to sham on pain sensitivity and nervous system response to various qualities of experimentally induced pain in the upper and lower extremities of subjects with…
- Trial name
- NCT02809911
- Testing
- Provant
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Regenesis Biomedical, Inc.
Diabetic Pheripheral Neuropathy
COMPARISON OF MULTISENSORY EXERCISE AND TIBIAL NERVE MOBILIZATION IN PATIENTS WITH TYPE 2 DIABETIC PERIPHERAL NEUROPATHY
Diabetes mellitus is a chronic metabolic condition characterized by high blood glucose levels due to insufficient insulin production or the body's inability to respond properly to insulin.
- Trial name
- VAS-BBS (NCT07909707)
- Testing
- Tibial nerve mobilization, Multisensory Excercise
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Qurat Ul Ain Ashfaq
Neuropathic Pain From Spinal Cord Injury, Diabetic Peripheral Neuropathy
Validation Study of Neuropathic Pain
This study seeks to validate clinically evoked or obtained objective pain signs with the patient's corresponding quantified subjective pain symptoms.
- Conditions
- Neuropathic Pain From Spinal Cord Injury, Diabetic Peripheral Neuropathy, Post Herpetic Pain
- Trial name
- NCT00623961
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Wisconsin, Madison
Diabetic Polyneuropathy, Diabetic Neuralgia
A Study of Phyllanthus Niruri and Sida Cordifolia in Diabetic Peripheral Polyneuropathy
The purpose of the study is to determine whether phyllanthus niruri and sida cordifolia are effective in treatment of diabetic polyneuropathy compared to placebo.
- Conditions
- Diabetic Polyneuropathy, Diabetic Neuralgia, Diabetic Neuropathies, Diabetic Neuropathy
- Trial name
- VEDICINE (NCT02107469)
- Testing
- Sida cordifolia roots, Phyllanthus niruri, Sida cordifolia roots extract
- Where
- India
- Volunteers
- 98 people
- Sponsor
- Rosenberg European Academy of Ayurveda
Pain, Diabetic Neuropathy
A Study of Sativex® for Pain Relief Due to Diabetic Neuropathy
The purpose of this study is to evaluate the efficacy of Sativex® compared with placebo in relieving pain due to Diabetic Neuropathy.
- Trial name
- NCT00710424
- Testing
- Sativex
- Where
- United Kingdom
- Volunteers
- 297 people
- Sponsor
- Jazz Pharmaceuticals
Painful Diabetic Peripheral Neuropathy (PDPN)
Study to Assess Analgesic Efficacy and Safety of ASP3662 in Subjects With Painful Diabetic Peripheral Neuropathy
The purpose of this study is to assess analgesic efficacy of ASP3662 relative to placebo in subjects with painful diabetic peripheral neuropathy (PDPN) as well as assess the safety and tolerability of ASP3662 relative to placebo.
- Trial name
- NCT02372578
- Testing
- ASP3662, pregabalin
- Where
- 37 sites in United States
- Volunteers
- 115 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Diabetic Foot Ulcer, Lower Extremity Amputation
Comparison of Anesthetic Modalities on Hemodynamic Stability and Postoperative Pain in Diabetic Foot Patients Undergoing Minor Lower Extremity Amputation
Diabetic foot ulcer is the most common cause of non traumatic lower extremity amputations (LEA) associated with diabetes. Traditionally general and spinal anesthesia were the preferred modality of anesthesia.
- Trial name
- NCT02440282
- Volunteers
- 86 people
- Sponsor
- Yonsei University