Clinical trials: Diabetic Peripheral Neuropathy (DPN)
Diabetic Peripheral Neuropathy, Pain
Different Amounts of Moxibustion in the Treatment of DPN: A Clinical RCT Study
This study aims to provide moxibustion treatment for diabetic peripheral neuropathy (DPN) and a reference for clinical treatment of DPN moxibustion.
- Conditions
- Diabetic Peripheral Neuropathy, Pain, Moxibustion, Randomized Controlled Trial
- Trial name
- NCT06330233
- Testing
- Moxibustion
- Where
- 3 sites in China
- Volunteers
- 90 people
- Sponsor
- Zhejiang Chinese Medical University
Diabetic Peripheral Neuropathy
Metanx® P.L.U.S. Program (Progress Through Learning, Understanding & Support)
This study will be an observational study in which patients who have been prescribed Metanx® are invited to participate in surveys regarding their experiences with Metanx®.
- Trial name
- NCT01368549
- Testing
- Metanx® (a medical food)
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Pamlab, L.L.C.
Diabetic Peripheral Neuropathic Pain (DPN), Diabetic Peripheral Neuropathy
Transcutaneous Pulsed Radiofrequency for the Treatment of Diabetic Peripheral Neuropathy Pain
The purpose of this study is to determine if a non-invasive, electrical pulsed radio frequency (PRF) device can relieve pain and improve function in patients suffering from diabetic nerve pain in their feet, known as pedal…
- Conditions
- Diabetic Peripheral Neuropathic Pain (DPN), Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain
- Trial name
- NCT07725419
- Testing
- NMS 460 Pulsed Radio Frequency Device
- Where
- 5 sites in South Africa
- Volunteers
- 92 people
- Sponsor
- Algiamed Technologies USA, Inc.
Diabetic Peripheral Neuropathic Pain
Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy (DPN)
To evaluate the efficacy of NYX-2925 versus placebo in treating the neuropathic pain associated with diabetic peripheral neuropathy.
- Trial name
- NCT04146896
- Testing
- NYX-2925 50 mg
- Where
- 35 sites in United States
- Volunteers
- 228 people
- Sponsor
- Aptinyx
Diabetic Peripheral Neuropathy (DPN)
The Diagnostic Value of Shear Wave Elastography and Viscosity Imaging Techniques in Diabetic Peripheral Neuropathy
The main objective of this observational study is to evaluate the diagnostic value of multimodal ultrasound for diabetic peripheral neuropathy (DPN).
- Trial name
- NCT06773793
- Where
- 2 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Diabetic Neuropathy, Painful, Diabetic Polyneuropathy
A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN)
The purpose of this study is to evaluate the safety profile of orally administered tapentadol ER dosages of 100 to 250 mg twice daily in patients with chronic, painful diabetic peripheral neuropathy (DPN) over long-term exposure…
- Trial name
- NCT01063868
- Testing
- Tapentadol extended release (ER), Oxycodone controlled release (CR)
- Where
- 23 sites in United States
- Volunteers
- 47 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Diabetic Peripheral Neuropathic Pain (DPN)
Medtronic Inceptiv™ Closed-Loop DTM Spinal Cord Stimulation for Painful Diabetic Peripheral Neuropathy
This study is conducted to evaluate a new way of using spinal cord stimulation (SCS) in people with painful diabetic peripheral neuropathy (DPN).
- Trial name
- MED DPN (NCT07209514)
- Testing
- Implantable SCS with Closed Loop mechanism
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- TriCity Research Center
Diabetic Peripheral Neuropathy (DPN)
Thymoquinone as an add-on Therapy for the Management of Patients With Diabetic Peripheral Neuropathy
The goal of this clinical trial is to evaluate the efficacy of thymoquinone as an adjuvant treatment with pregabalin in the management of diabetic peripheral neuropathy for both sexes older than 18 years.
- Trial name
- TQDPN (NCT07313111)
- Testing
- stander treatment pregabalin, thymoquinone
- Where
- Iraq
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Diabetic Peripheral Neuropathy (DPN)
BRACE(Balance, Resistance, Aerobic and Cognitive Exercise) Protocol for Diabetic).Peripheral Neuropathic Patients.
The purpose of the study is to determine the effects of the BRACE( Balance, Resistance, Aerobic and Cognitive Exercise) protocol for balance training in patients with Diabetic Peripheral Neuropathy.
- Trial name
- NCT04832464
- Testing
- RACE Protocol: Balance training along with resistance, aerobic and cognitive exercises.
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Diabetic Peripheral Neuropathy
12-Month Efficacy and Safety of Diepalrestat in Adults With Diabetic Peripheral Neuropathy, a DB, Placebo-Controlled Study
An interventional study to investigate the efficacy and safety of diepalrestat (BNV-222) in diabetic patients with diabetic peripheral neuropathy.
- Trial name
- DE-DPN (NCT02332005)
- Testing
- diepalrestat choline
- Where
- 27 sites in Russia
- Volunteers
- 330 people
- Sponsor
- NeuromaxBionevia
Diabetic Peripheral Neuropathy (DPN), Electroacupuncture
Effect of Low-Frequency Electroacupuncture on Diabetic Peripheral Neuropathy
Diabetic peripheral neuropathy (DPN) is a common and disabling complication of diabetes. Many patients experience pain, numbness, and impaired quality of life, while currently available treatments may have limited benefit or…
- Trial name
- NCT07551726
- Testing
- EA
- Volunteers
- 92 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Diabetic Neuropathies
Effect of High-Dose NAC on Patients With DPN
The aim of the current study is to evaluate the efficacy and safety of high dose oral NAC (2400 mg/day divided into two doses) as an adjunct therapy on oxidative stress, inflammatory markers and clinical outcome in patients with…
- Trial name
- NAC (NCT04766450)
- Testing
- Acetyl cysteine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Diabetic Peripheral Neuropathy
Effects of Multisystem Exercise on Balance, Postural Stability, Mobility and Pain in Patients With DPN.
Upto the best knowledge of researcher, multisystem exercise program has been utilized in various populations, encompassing both healthy individuals and patients with diverse medical conditions.
- Trial name
- DPN (NCT06130917)
- Testing
- Multisystem Exercise, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Diabetic Peripheral Neuropathy
Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN)
The purpose of this study is to evaluate the efficacy and safety of VX-548 doses in treating Painful DPN.
- Trial name
- NCT05660538
- Testing
- Suzetrigine, Pregabalin
- Where
- 50 sites in United States
- Volunteers
- 194 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Diabetic Peripheral Neuropathy (DPN)
Effects of Insole Vibration With Proprioceptive Training in Patients With Diabetic Peripheral Neuropathy
Diabetic peripheral neuropathy (DPN) is a prevalent complication of diabetes, profoundly affecting quality of life with sensory disturbances and associated complications.
- Trial name
- NCT07128836
- Testing
- proprioceptive training exercise and receive insole vibrator, proprioceptive training exercise along with simple insoles without vibration
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Patient Compliance
A Randomized Controlled Trial to Assess the Effect of L-carnitine in Patients With Diabetic Peripheral Neuropathy to Relief Pain and Symptom Improvement
Diabetic Peripheral Neuropathy (DPN) is a common complication of diabetes mellitus. The prevalence rate is approaching towards a peak throughout the world including Bangladesh.
- Trial name
- NCT04145245
- Testing
- Levocarnitine
- Where
- Bangladesh
- Volunteers
- 104 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Painful Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain (DPN)
SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy.
The goal of this clinical trial is to determine whether quantitative sensory testing (QST) can be used to classify participants into pain sub-groups and predict who will respond best to certain pain treatments in participants…
- Conditions
- Painful Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain (DPN), Chemotherapy Induced Peripheral Neuropathy (CIPN), Idiopathic Peripheral Neuropathy
- Trial name
- NCT06614322
- Testing
- Pregabalin, Duloxetine
- Where
- 7 sites in United States
- Volunteers
- 190 people
- Sponsor
- University of Rochester
Diabetic Peripheral Neuropathy
Safety and Efficacy of Gabapentin in Diabetic Peripheral Neuropathy
The purpose of this study is to determine whether a new Gabapentin tablet, is safe and effective for the treatment of painful diabetic peripheral neuropathy.
- Trial name
- NCT00712439
- Testing
- Gabapentin Extended Release tablets
- Volunteers
- 147 people
- Sponsor
- Depomed
Diabetic Peripheral Neuropathy
Effect of Vitamin D in Patients With Diabetic Peripheral Neuropathy to Alleviate Pain and Improvement of Symptoms
Diabetic peripheral neuropathy(DPN) is one of the major complications of diabetes mellitus which accelerates the occurrence of ulceration of diabetic foot and amputation of lower extremities as well as severely affects the…
- Trial name
- NCT04984044
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 72 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Diabetic Neuropathy, Painful, Diabetic Neuralgia
Study for Safety and Effectiveness of RWJ-333369 (Carsibamate) for the Treatment of Diabetic Peripheral Neuropathy (DPN).
The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily by mouth compared with placebo in the treatment of Diabetic Peripheral Neuropathy (DPN).
- Conditions
- Diabetic Neuropathy, Painful, Diabetic Neuralgia, Diabetic Polyneuropathy, Diabetic Mononeuropathy
- Trial name
- NCT00501202
- Testing
- RWJ-333369 (carisbamate)
- Volunteers
- 132 people
- Sponsor
- SK Life Science, Inc.